| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoping Yu, Jundong Zhu, Mantian Mi, Wei Chen, Qu Pan, Min We. Anti-angiogenic genistein inhibits VEGF-induced endothelial cell activation by decreasing PTK activity and MAPK activation. Medical oncology (Northwood, London, England). vol 29. issue 1. 2012-08-23. PMID:21132400. |
treatment of ecs with genistein induced vegf-loaded endothelial apoptosis by inhibiting production and activity of matrix metalloproteinases (mmps). |
2012-08-23 |
2023-08-12 |
human |
| Hyun-Kyung Park, Dae Jean J. Polymorphisms of integrin, alpha 6 contribute to the development and neurologic symptoms of intracerebral hemorrhage in korean population. Journal of Korean Neurosurgical Society. vol 50. issue 4. 2012-08-23. PMID:22200009. |
the extracellular matrix (ecm) and cell adhesion molecules play crucial roles in angiogenesis, apoptosis, thrombosis, and inflammation, and also contribute to the pathogenesis of stroke. |
2012-08-23 |
2023-08-12 |
Not clear |
| Tao Wang, Lucia R Languino, Jane Lian, Gary Stein, Michael Blute, Thomas J Fitzgeral. Molecular targets for radiation oncology in prostate cancer. Frontiers in oncology. vol 1. 2012-08-23. PMID:22645712. |
in this review, we focus on molecules of extracellular matrix component, apoptosis, androgen receptor, runx, and dna methylation. |
2012-08-23 |
2023-08-12 |
Not clear |
| Kostas Archontogeorgis, Paschalis Steiropoulos, Argyris Tzouvelekis, Evangelia Nena, Demosthenes Bouro. Lung cancer and interstitial lung diseases: a systematic review. Pulmonary medicine. vol 2012. 2012-08-23. PMID:22900168. |
different studies suggest a link between ilds and lung cancer, through different pathogenetic mechanisms, such as inflammation, coagulation, dysregulated apoptosis, focal hypoxia, activation, and accumulation of myofibroblasts as well as extracellular matrix accumulation. |
2012-08-23 |
2023-08-12 |
Not clear |
| X-M Jing, Y-J Wen, W Shi, Q-Q Tang, J Li, X-C Che. VSV-MP gene therapy strategy inhibits tumor growth in nude mice model of human lung adenocarcinoma. Cancer gene therapy. vol 19. issue 2. 2012-08-16. PMID:22052213. |
vesicular stomatitis virus (vsv) matrix protein (mp) can induce in vitro apoptosis of tumor cells in the absence of other viral components. |
2012-08-16 |
2023-08-12 |
mouse |
| Thor Ueland, Arne Yndestad, Christen P Dahl, Lars Gullestad, Pål Aukrus. TNF revisited: osteoprotegerin and TNF-related molecules in heart failure. Current heart failure reports. vol 9. issue 2. 2012-08-14. PMID:22453763. |
by activating the nuclear factor-κb (nf-κb) and death-related pathways, tnf ligands can induce a variety of effects within the myocardium, including apoptosis, hypertrophy, inflammation, and extracellular matrix remodeling. |
2012-08-14 |
2023-08-12 |
Not clear |
| Abu P Abraham, Frank Y Ma, William R Mulley, Elyce Ozols, David J Nikolic-Paterso. Macrophage infiltration and renal damage are independent of matrix metalloproteinase 12 in the obstructed kidney. Nephrology (Carlton, Vic.). vol 17. issue 4. 2012-08-13. PMID:22257277. |
to determine whether matrix metalloproteinase-12 (mmp-12) plays a functional role in renal interstitial macrophage accumulation, interstitial fibrosis or tubular apoptosis in the unilateral ureteric obstruction (uuo) model. |
2012-08-13 |
2023-08-12 |
Not clear |
| Rhonda M Perciavalle, Daniel P Stewart, Brian Koss, John Lynch, Sandra Milasta, Madhavi Bathina, Jamshid Temirov, Megan M Cleland, Stéphane Pelletier, John D Schuetz, Richard J Youle, Douglas R Green, Joseph T Opferma. Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration. Nature cell biology. vol 14. issue 6. 2012-08-13. PMID:22544066. |
on the outer mitochondrial membrane, an mcl-1 isoform acts like other anti-apoptotic bcl-2 molecules to antagonize apoptosis, whereas an amino-terminally truncated isoform of mcl-1 that is imported into the mitochondrial matrix is necessary to facilitate normal mitochondrial fusion, atp production, membrane potential, respiration, cristae ultrastructure and maintenance of oligomeric atp synthase. |
2012-08-13 |
2023-08-12 |
Not clear |
| Joshua L Andersen, Sally Kornblut. Mcl-1 rescues a glitch in the matrix. Nature cell biology. vol 14. issue 6. 2012-08-13. PMID:22643875. |
however, a cleaved form of mcl-1 localizes to the mitochondrial matrix and controls inner mitochondrial morphology and oxidative phosphorylation, without directly modulating apoptosis. |
2012-08-13 |
2023-08-12 |
Not clear |
| Yoshiteru Tada, Keiko T Kitazato, Kenji Yagi, Kenji Shimada, Nobuhisa Matsushita, Tomoya Kinouchi, Yasuhisa Kanematsu, Junichiro Satomi, Teruyoshi Kageji, Shinji Nagahir. Statins promote the growth of experimentally induced cerebral aneurysms in estrogen-deficient rats. Stroke. vol 42. issue 8. 2012-08-10. PMID:21737796. |
the pathogenesis of cerebral aneurysms is linked to inflammation, degradation of the extracellular matrix, and vascular wall apoptosis. |
2012-08-10 |
2023-08-12 |
rat |
| Claudia R de Andrade, Beatriz S Stolf, Victor Debbas, Daniela S Rosa, Jorge Kalil, Veronica Coelho, Francisco R M Laurind. Quiescin sulfhydryl oxidase (QSOX) is expressed in the human atheroma core: possible role in apoptosis. In vitro cellular & developmental biology. Animal. vol 47. issue 10. 2012-08-10. PMID:22069028. |
qsox1, the most extensively studied type, has been implicated in protein folding, production of extracellular matrix, redox regulation, protection from apoptosis, angiogenesis, and cell differentiation. |
2012-08-10 |
2023-08-12 |
human |
| Claudia R de Andrade, Beatriz S Stolf, Victor Debbas, Daniela S Rosa, Jorge Kalil, Veronica Coelho, Francisco R M Laurind. Quiescin sulfhydryl oxidase (QSOX) is expressed in the human atheroma core: possible role in apoptosis. In vitro cellular & developmental biology. Animal. vol 47. issue 10. 2012-08-10. PMID:22069028. |
atherosclerosis is an immunopathological condition in which redox processes, apoptosis, cell differentiation, and matrix secretion/maturation have critical roles. |
2012-08-10 |
2023-08-12 |
human |
| Emma Dean, Alastair Greystoke, Malcolm Ranson, Caroline Div. Biomarkers of cell death applicable to early clinical trials. Experimental cell research. vol 318. issue 11. 2012-08-10. PMID:22483936. |
tumor biopsies are an ideal matrix to measure apoptosis, but surrogate less invasive biomarkers such as blood samples and functional imaging are less challenging to acquire clinically. |
2012-08-10 |
2023-08-12 |
Not clear |
| S K Özel, H Emir, S Dervişoğlu, N Akpolat, B Şenel, A Kazez, Y Söylet, G Çetin, N Danişmend, S N C Büyüküna. The roles of extracellular matrix proteins, apoptosis and c-kit positive cells in the pathogenesis of ureteropelvic junction obstruction. Journal of pediatric urology. vol 6. issue 2. 2012-08-06. PMID:19716769. |
the roles of extracellular matrix proteins, apoptosis and c-kit positive cells in the pathogenesis of ureteropelvic junction obstruction. |
2012-08-06 |
2023-08-12 |
Not clear |
| Janice Gerloff, Vyacheslav A Korshuno. Immune modulation of vascular resident cells by Axl orchestrates carotid intima-media thickening. The American journal of pathology. vol 180. issue 5. 2012-08-06. PMID:22538191. |
our data suggest that axl contributes to carotid remodeling not only by inhibition of apoptosis but also via regulation of immune heterogeneity of vascular cells, cytokine/chemokine expression, and extracellular matrix remodeling. |
2012-08-06 |
2023-08-12 |
Not clear |
| Joel Gaston, Beatriz Quinchia Rios, Rebecca Bartlett, Craig Berchtold, Susan L Thibeaul. The response of vocal fold fibroblasts and mesenchymal stromal cells to vibration. PloS one. vol 7. issue 2. 2012-08-03. PMID:22359557. |
immunohistochemistry (ki-67 and tunel) was performed to examine cell proliferation and apoptosis respectively, while semi-quantitative rt-pcr was used to assess extracellular matrix related gene expression. |
2012-08-03 |
2023-08-12 |
human |
| Byong Hoon Yoo, Alexander Berezkin, Yanfei Wang, Anna Zagryazhskaya, Kirill V Rose. Tumor suppressor protein kinase Chk2 is a mediator of anoikis of intestinal epithelial cells. International journal of cancer. vol 131. issue 2. 2012-07-30. PMID:21834075. |
resistance of carcinoma cells to anoikis, apoptosis that is normally induced by detachment of nonmalignant epithelial cells from the extracellular matrix, is thought to be critical for carcinoma progression. |
2012-07-30 |
2023-08-12 |
Not clear |
| Yan Zhou, Xianshu Tan, Wenjuan Kuang, Litao Liu, Lihong Wa. Erythromycin ameliorates cigarette-smoke-induced emphysema and inflammation in rats. Translational research : the journal of laboratory and clinical medicine. vol 159. issue 6. 2012-07-27. PMID:22633097. |
erythromycin protected significantly against the alveolar enlargement levels (p = 0.0017), reduced the pathologic apoptosis (p = 0.0023) related with bcl-2 (p = 0.0002) and bax (p = 0.0002), and inhibited the expressions of matrix metalloproteinase (mmp)-9 (p = 0.0019) and timp-1 protein (p = 0.04) and the mmp-9/timp-1 ratio (p = 0.0002) in the lungs of cs-induced emphysema in rats. |
2012-07-27 |
2023-08-12 |
rat |
| Jennifer L Leight, Michele A Wozniak, Sophia Chen, Michelle L Lynch, Christopher S Che. Matrix rigidity regulates a switch between TGF-β1-induced apoptosis and epithelial-mesenchymal transition. Molecular biology of the cell. vol 23. issue 5. 2012-07-23. PMID:22238361. |
matrix rigidity regulates a switch between tgf-β1-induced apoptosis and epithelial-mesenchymal transition. |
2012-07-23 |
2023-08-12 |
Not clear |
| Hanna E Abbou. Mesangial cell biology. Experimental cell research. vol 318. issue 9. 2012-07-13. PMID:22414873. |
in response to metabolic, immunologic or hemodynamic injury, these cells undergo apoptosis or acquire an activated phenotype and undergo hypertrophy, proliferation with excessive production of matrix proteins, growth factors, chemokines and cytokines. |
2012-07-13 |
2023-08-12 |
Not clear |