| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ibrahim C Haznedaroglu, Yavuz Beyazi. Local bone marrow renin-angiotensin system in primitive, definitive and neoplastic haematopoiesis. Clinical science (London, England : 1979). vol 124. issue 5. 2013-01-24. PMID:23157407. |
the local tissue ras influences tumour growth and metastases in an autocrine and paracrine fashion via the modulation of numerous carcinogenic events, such as angiogenesis, apoptosis, cellular proliferation, immune responses, cell signalling and extracellular matrix formation. |
2013-01-24 |
2023-08-12 |
Not clear |
| Franziska Busch, Ali Mobasheri, Parviz Shayan, Cora Lueders, Ralf Stahlmann, Mehdi Shakibae. Resveratrol modulates interleukin-1β-induced phosphatidylinositol 3-kinase and nuclear factor κB signaling pathways in human tenocytes. The Journal of biological chemistry. vol 287. issue 45. 2013-01-23. PMID:22936809. |
treatment with resveratrol enhanced the production of matrix components collagen types i and iii, tenomodulin, and tenogenic transcription factor scleraxis, whereas it inhibited gene products involved in inflammation and apoptosis. |
2013-01-23 |
2023-08-12 |
human |
| Sanaz Sanii, Hiva Saffar, Hedieh M Tabriz, Mostafa Qorbani, Vahid Haghpanah, Seyed M Tavanga. Expression of matrix metalloproteinase-2, but not caspase-3, facilitates distinction between benign and malignant thyroid follicular neoplasms. Asian Pacific journal of cancer prevention : APJCP. vol 13. issue 5. 2013-01-22. PMID:22901190. |
matrix metalloproteinase-2 (mmp-2), by degrading extracellular matrix, and caspase-3, by induction of apoptosis, have been shown to play important roles in carcinogenesis and aggressive behavior in many tumor types. |
2013-01-22 |
2023-08-12 |
Not clear |
| P Ramachandran, J P Iredal. Liver fibrosis: a bidirectional model of fibrogenesis and resolution. QJM : monthly journal of the Association of Physicians. vol 105. issue 9. 2013-01-16. PMID:22647759. |
we will highlight some of the mechanisms responsible for fibrogenesis and fibrosis regression, focussing on the role of hepatic myofibroblast activation and apoptosis, the importance of matrix metalloproteinases and their tissue inhibitors and the central involvement of hepatic macrophages in orchestrating this process. |
2013-01-16 |
2023-08-12 |
human |
| Federico Carlos Blanco, Marcelo Soria, María Verónica Bianco, Fabiana Big. Transcriptional response of peripheral blood mononuclear cells from cattle infected with Mycobacterium bovis. PloS one. vol 7. issue 7. 2013-01-16. PMID:22815916. |
the highest differentially-expressed genes were related to immune and inflammatory responses, apoptosis, endocytosis, cellular trafficking and genes encoding proteins involved in cellular matrix degradation. |
2013-01-16 |
2023-08-12 |
cattle |
| S Yoshida, N Minematsu, S Chubachi, H Nakamura, M Miyazaki, K Tsuduki, S Takahashi, T Miyasho, T Iwabuchi, R Takamiya, H Tateno, M Mouded, S D Shapiro, K Asano, T Betsuyak. Annexin V decreases PS-mediated macrophage efferocytosis and deteriorates elastase-induced pulmonary emphysema in mice. American journal of physiology. Lung cellular and molecular physiology. vol 303. issue 10. 2013-01-15. PMID:22962014. |
cell profile, apoptosis, and mrna expression of matrix metalloproteinases (mmps) and growth factors were evaluated in bronchoalveolar lavage (bal) cells on day 15. |
2013-01-15 |
2023-08-12 |
mouse |
| Atsushi Tomokiyo, Hidefumi Maeda, Shinsuke Fujii, Satoshi Monnouchi, Naohisa Wada, Kiyomi Hori, Katsuaki Koori, Naohide Yamamoto, Yoko Teramatsu, Akifumi Akamin. Alternation of extracellular matrix remodeling and apoptosis by activation of the aryl hydrocarbon receptor pathway in human periodontal ligament cells. Journal of cellular biochemistry. vol 113. issue 10. 2013-01-07. PMID:22581694. |
alternation of extracellular matrix remodeling and apoptosis by activation of the aryl hydrocarbon receptor pathway in human periodontal ligament cells. |
2013-01-07 |
2023-08-12 |
human |
| Atsushi Tomokiyo, Hidefumi Maeda, Shinsuke Fujii, Satoshi Monnouchi, Naohisa Wada, Kiyomi Hori, Katsuaki Koori, Naohide Yamamoto, Yoko Teramatsu, Akifumi Akamin. Alternation of extracellular matrix remodeling and apoptosis by activation of the aryl hydrocarbon receptor pathway in human periodontal ligament cells. Journal of cellular biochemistry. vol 113. issue 10. 2013-01-07. PMID:22581694. |
here, we investigated the effects of benzo(a)pyrene (bap), a member of pah, on the extracellular matrix (ecm) remodeling-related molecules, collagen type i (col-i), matrix metalloproteinase-1 (mmp-1), alpha-smooth muscle actin (α-sma) expression, and apoptosis in two different human periodontal ligament cells (hpdlcs). |
2013-01-07 |
2023-08-12 |
human |
| Ceyda Acilan, Muge Serhatli, Omer Kacar, Zelal Adiguzel, Altug Tuncer, Mutlu Hayran, Kemal Baysa. Smooth muscle cells isolated from thoracic aortic aneurysms exhibit increased genomic damage, but similar tendency for apoptosis. DNA and cell biology. vol 31. issue 10. 2013-01-03. PMID:22871164. |
during the development of aa, two key structural changes are pronounced, one being degradation of extracellular matrix and the other loss of smooth muscle cells (smcs) through apoptosis. |
2013-01-03 |
2023-08-12 |
Not clear |
| Wesley M Jackson, Leon J Nesti, Rocky S Tua. Concise review: clinical translation of wound healing therapies based on mesenchymal stem cells. Stem cells translational medicine. vol 1. issue 1. 2013-01-03. PMID:23197639. |
these in vivo studies provide overwhelming evidence that mscs can accelerate wound closure by modulating the inflammatory environment, promoting the formation of a well-vascularized granulation matrix, encouraging the migration of keratinocytes, and inhibiting apoptosis of wound healing cells. |
2013-01-03 |
2023-08-12 |
Not clear |
| Leonard H Siga. Basic science for the clinician 57: transforming growth factor β. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. vol 18. issue 5. 2012-12-20. PMID:22832292. |
in general terms, transforming growth factor β (tgf-β) is intimately involved in a variety of differentiation and growth inhibition processes, in apoptosis, and in deposition of the extracellular matrix. |
2012-12-20 |
2023-08-12 |
Not clear |
| J W Hill, R Poddar, J F Thompson, G A Rosenberg, Y Yan. Intranuclear matrix metalloproteinases promote DNA damage and apoptosis induced by oxygen-glucose deprivation in neurons. Neuroscience. vol 220. 2012-12-14. PMID:22710064. |
intranuclear matrix metalloproteinases promote dna damage and apoptosis induced by oxygen-glucose deprivation in neurons. |
2012-12-14 |
2023-08-12 |
rat |
| Manoj Bhasin, Zhen Huang, Leena Pradhan-Nabzdyk, Junaid Y Malek, Philip J LoGerfo, Mauricio Contreras, Patrick Guthrie, Eva Csizmadia, Nicholas Andersen, Olivier Kocher, Christiane Ferran, Frank W LoGerf. Temporal network based analysis of cell specific vein graft transcriptome defines key pathways and hub genes in implantation injury. PloS one. vol 7. issue 6. 2012-12-13. PMID:22720046. |
our results demonstrate a robust genomic response beginning at 2 h, peaking at 12-24 h, declining by 7 d, and resolving by 30 d. gene ontology and pathway analyses of differentially expressed genes indicated that implantation injury affects inflammatory and immune responses, apoptosis, mitosis, and extracellular matrix reorganization in both cell types. |
2012-12-13 |
2023-08-12 |
Not clear |
| Yingmei Zhang, Nan Hu, Yinan Hua, Kacy L Richmond, Feng Dong, Jun Re. Cardiac overexpression of metallothionein rescues cold exposure-induced myocardial contractile dysfunction through attenuation of cardiac fibrosis despite cardiomyocyte mechanical anomalies. Free radical biology & medicine. vol 53. issue 2. 2012-12-11. PMID:22565031. |
cold exposure increased plasma levels of norepinephrine, endothelin-1, and tgf-β; reduced plasma no levels and cardiac antioxidant capacity; enlarged ventricular end-systolic diameter; compromised fractional shortening; promoted reactive oxygen species (ros) production and apoptosis; and suppressed the er stress markers bip, calregulin, and phospho-eif2α, accompanied by cardiac fibrosis and elevated levels of matrix metalloproteinases and smad-2/3 in fvb mice. |
2012-12-11 |
2023-08-12 |
mouse |
| Isabel L Jackson, Xiuwu Zhang, Caroline Hadley, Zahid N Rabbani, Yu Zhang, Sam Marks, Zeljko Vujaskovi. Temporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lung. Free radical biology & medicine. vol 53. issue 2. 2012-12-11. PMID:22588005. |
forty-four genes associated with metabolism, cell growth, apoptosis, inflammation, oxidative stress, and extracellular matrix synthesis were upregulated after radiation. |
2012-12-11 |
2023-08-12 |
mouse |
| Shigeru Kihira, Junpei Yoshida, Yukari Kawada, Yuriko Hitomi, Tomohisa Asada, Rie Hisatomi, Akina Ohta, Tetsushi Iwasaki, A K M Mahbub Hasan, Yasuo Fukami, Ken-Ichi Sat. Membrane microdomain-associated uroplakin IIIa contributes to Src-dependent mechanisms of anti-apoptotic proliferation in human bladder carcinoma cells. Biology open. vol 1. issue 10. 2012-12-06. PMID:23213380. |
gm6001, a potent inhibitor of matrix metalloproteinase (mmp), inhibits the proteolysis of upiiia and promotes apoptosis in serum-starved cells. |
2012-12-06 |
2023-08-12 |
human |
| Maneli Mozaffarieh, Stefan Fraenkl, Katarzyna Konieczka, Josef Flamme. Targeted preventive measures and advanced approaches in personalised treatment of glaucoma neuropathy. The EPMA journal. vol 1. issue 2. 2012-12-04. PMID:23199061. |
suppression of matrix metalloproteinase-9 inhibits apoptosis of retinal ganglion cells and tissue remodelling. |
2012-12-04 |
2023-08-12 |
Not clear |
| Olivia Fromigué, Julia Brun, Caroline Marty, Sophie Da Nascimento, Pascal Sonnet, Pierre J Mari. Peptide-based activation of alpha5 integrin for promoting osteogenesis. Journal of cellular biochemistry. vol 113. issue 9. 2012-11-16. PMID:22566152. |
in vitro, peptide-based activation of itga5 protected from cell apoptosis but did not affect cell adhesion or replication, while it enhanced the expression of the osteoblast marker genes runx2 and type i collagen and increased extracellular matrix (ecm) mineralization as also found with bone morphogenetic protein-2 (bmp2), a standard bone anabolic factor. |
2012-11-16 |
2023-08-12 |
mouse |
| Roman Thaler, Silvia Spitzer, Heidrun Karlic, Klaus Klaushofer, Franz Varg. DMSO is a strong inducer of DNA hydroxymethylation in pre-osteoblastic MC3T3-E1 cells. Epigenetics. vol 7. issue 6. 2012-11-09. PMID:22507896. |
at this time, up regulation of genes important for matrix synthesis suggests that dmso via hydroxymethylation of the fas promoter initially stimulates apoptosis in a subpopulation of the heterogeneous mc3t3-e1 cell line, leaving a cell population of extra-cellular matrix producing osteoblasts. |
2012-11-09 |
2023-08-12 |
Not clear |
| Maria V Nurminskaya, Alexey M Belki. Cellular functions of tissue transglutaminase. International review of cell and molecular biology. vol 294. 2012-11-07. PMID:22364871. |
a vast array of biochemical activities of tg2 accounts for its involvement in a variety of cellular processes, including adhesion, migration, growth, survival, apoptosis, differentiation, and extracellular matrix organization. |
2012-11-07 |
2023-08-12 |
Not clear |