| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Feifei Li, Yaojuan Lu, Ming Ding, Guojun Wu, Satrajit Sinha, Siying Wang, Qiping Zhen. Putative function of TAP63α during endochondral bone formation. Gene. vol 495. issue 2. 2012-04-10. PMID:22244744. |
tap63a may promote endochondral ossification through interaction with genes relevant to matrix mineralization and chondrocyte maturation or apoptosis. |
2012-04-10 |
2023-08-12 |
mouse |
| Wolfgang Kemmner, Pia Kessel, Hugo Sanchez-Ruderisch, Heinz Möller, Stephan Hinderlich, Peter M Schlag, Katharina Detje. Loss of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) induces apoptotic processes in pancreatic carcinoma cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 26. issue 2. 2012-04-09. PMID:22049060. |
early invasive growth and metastasis are features of pancreatic cancer that rely on its resistance to anoikis, an apoptosis program activated on loss of matrix anchorage. |
2012-04-09 |
2023-08-12 |
human |
| Ting-Ting Tang, Jing Yuan, Zheng-Feng Zhu, Wen-Cai Zhang, Hong Xiao, Ni Xia, Xin-Xin Yan, Shao-Fang Nie, Juan Liu, Su-Feng Zhou, Jing-Jing Li, Rui Yao, Meng-Yang Liao, Xin Tu, Yu-Hua Liao, Xiang Chen. Regulatory T cells ameliorate cardiac remodeling after myocardial infarction. Basic research in cardiology. vol 107. issue 1. 2012-04-09. PMID:22189560. |
interstitial fibrosis, myocardial matrix metalloproteinase-2 activity and cardiac apoptosis were attenuated in the rats that received treg cells transfer. |
2012-04-09 |
2023-08-12 |
rat |
| Juan R Velazque. The monocyte locomotion inhibitory factor an anti-inflammatory peptide; therapeutics originating from amebic abscess of the liver. Recent patents on endocrine, metabolic & immune drug discovery. vol 5. issue 1. 2012-04-06. PMID:22074573. |
microarray data from experimental arthritis revealed an mlif gene expression profile that includes genes that are involved in apoptosis, cell adhesion, extracellular matrix, and inflammation / chemotaxis. |
2012-04-06 |
2023-08-12 |
human |
| Virginia Egea, Stefan Zahler, Nicole Rieth, Peter Neth, Tanja Popp, Kai Kehe, Marianne Jochum, Christian Rie. Tissue inhibitor of metalloproteinase-1 (TIMP-1) regulates mesenchymal stem cells through let-7f microRNA and Wnt/β-catenin signaling. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 6. 2012-03-30. PMID:22223664. |
tissue inhibitor of metalloproteinases 1 (timp-1) is a matrix metalloproteinase (mmp)-independent regulator of growth and apoptosis in various cell types. |
2012-03-30 |
2023-08-12 |
human |
| Tibor Szarvas, Frank vom Dorp, Süleyman Ergün, Herbert Rübbe. Matrix metalloproteinases and their clinical relevance in urinary bladder cancer. Nature reviews. Urology. vol 8. issue 5. 2012-03-26. PMID:21487384. |
matrix metalloproteinases (mmps) have important roles in several cancer-supporting cellular processes, such as extracellular matrix (ecm) remodeling, angiogenesis, apoptosis, epithelial-to-mesenchymal transition and cell proliferation. |
2012-03-26 |
2023-08-12 |
human |
| Graham S T Smith, Janine A M Voyer-Grant, George Harau. Monitoring cleaved caspase-3 activity and apoptosis of immortalized oligodendroglial cells using live-cell imaging and cleaveable fluorogenic-dye substrates following potassium-induced membrane depolarization. Journal of visualized experiments : JoVE. issue 59. 2012-03-26. PMID:22294086. |
here, the n19-olg cell cultures were treated with either 80 mm potassium chloride or 100 mm sodium glutamate to mimic axonal leakage into the extracellular matrix to induce apoptosis. |
2012-03-26 |
2023-08-12 |
Not clear |
| Mohammad R Noori-Daloii, Majid Momeny, Mehdi Yousefi, Forough Golsaz Shirazi, Mehdi Yaseri, Nasrin Motamed, Nazanin Kazemialiakbar, Saeed Hashem. Multifaceted preventive effects of single agent quercetin on a human prostate adenocarcinoma cell line (PC-3): implications for nutritional transcriptomics and multi-target therapy. Medical oncology (Northwood, London, England). vol 28. issue 4. 2012-03-22. PMID:20596804. |
quercetin inhibited cell proliferation and modulated the expression of genes involved in dna repair, matrix degradation and tumor invasion, angiogenesis, apoptosis, cell cycle, metabolism and glycolysis. |
2012-03-22 |
2023-08-12 |
human |
| E Maquoi, D Assent, J Detilleux, C Pequeux, J-M Foidart, A Noë. MT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis. Oncogene. vol 31. issue 4. 2012-03-20. PMID:21706048. |
we demonstrate that membrane type-1 matrix metalloproteinase (mt1-mmp/mmp-14) confers breast cancer cells with the ability to escape apoptosis when embedded in a collagen gel and after orthotopic implantation in vivo. |
2012-03-20 |
2023-08-12 |
Not clear |
| Shiao-Ying Chang, Yun-Wen Chen, Isabelle Chenier, Stella Le Minh Tran, Shao-Ling Zhan. Angiotensin II type II receptor deficiency accelerates the development of nephropathy in type I diabetes via oxidative stress and ACE2. Experimental diabetes research. vol 2011. 2012-03-15. PMID:22110472. |
after 4 weeks of diabetes, compared to wt controls, at(2)rko mice clearly developed features of early diabetic nephropathy (dn), such as renal hypertrophy, tubular apoptosis, and progressive extracellular matrix (ecm) protein accumulation as well as increased gfr. |
2012-03-15 |
2023-08-12 |
mouse |
| Giancarlo Forte, Stefano Pietronave, Giorgia Nardone, Andrea Zamperone, Eugenio Magnani, Stefania Pagliari, Francesca Pagliari, Cristina Giacinti, Carmine Nicoletti, Antonio Musaró, Mauro Rinaldi, Marco Ribezzo, Chiara Comoglio, Enrico Traversa, Teruo Okano, Marilena Minieri, Maria Prat, Paolo Di Nard. Human cardiac progenitor cell grafts as unrestricted source of supernumerary cardiac cells in healthy murine hearts. Stem cells (Dayton, Ohio). vol 29. issue 12. 2012-03-12. PMID:22009661. |
in the engineered tissue, progenitor cells established proper three-dimensional intercellular relationships and were embedded in self-produced extracellular matrix preserving their phenotype and multipotency in the absence of significant apoptosis. |
2012-03-12 |
2023-08-12 |
human |
| Tingting Li, Hongbo Tian, Yuxia Zhao, Fengshuang An, Lei Zhang, Jianning Zhang, Jie Peng, Yun Zhang, Yuan Gu. Heme oxygenase-1 inhibits progression and destabilization of vulnerable plaques in a rabbit model of atherosclerosis. European journal of pharmacology. vol 672. issue 1-3. 2012-03-07. PMID:22004613. |
in addition, hemin treatment is associated with a reduction in matrix metalloproteinase-9, interleukin-6 and tumor necrosis factor-α production, an increase in interleukin-10 level, as well as a decrease of tunel labeled apoptosis of smooth muscle cells in lesions. |
2012-03-07 |
2023-08-12 |
rabbit |
| Claudia Nicolaije, Marijke Koedam, Johannes P T M van Leeuwe. Decreased oxygen tension lowers reactive oxygen species and apoptosis and inhibits osteoblast matrix mineralization through changes in early osteoblast differentiation. Journal of cellular physiology. vol 227. issue 4. 2012-03-05. PMID:21604266. |
decreased oxygen tension lowers reactive oxygen species and apoptosis and inhibits osteoblast matrix mineralization through changes in early osteoblast differentiation. |
2012-03-05 |
2023-08-12 |
human |
| Joanne Ngeow, Iain Beehuat Tan, Su Pin Cho. Targeted therapies in the treatment of gastric cancer. Asia-Pacific journal of clinical oncology. vol 7. issue 3. 2012-03-02. PMID:21884434. |
these therapeutic strategies include epidermal growth factor receptor inhibitors, antiangiogenic agents, cell cycle inhibitors, apoptosis, promoters and matrix metalloproteinases inhibitors. |
2012-03-02 |
2023-08-12 |
Not clear |
| Priya Prakash Karmali, Chris Brunquell, Hau Tram, Shubha Kale Ireland, Erkki Ruoslahti, Hector Bilira. Metastasis of tumor cells is enhanced by downregulation of Bit1. PloS one. vol 6. issue 8. 2012-02-24. PMID:21886829. |
resistance to anoikis, which is defined as apoptosis induced by loss of integrin-mediated cell attachment to the extracellular matrix, is a determinant of tumor progression and metastasis. |
2012-02-24 |
2023-08-12 |
Not clear |
| Neal L Millar, James H Reilly, Shauna C Kerr, Abigail L Campbell, Kevin J Little, William J Leach, Brian P Rooney, George A C Murrell, Iain B McInne. Hypoxia: a critical regulator of early human tendinopathy. Annals of the rheumatic diseases. vol 71. issue 2. 2012-02-21. PMID:21972243. |
to seek evidence for the role of hypoxia in early human tendinopathy, and thereafter to explore mechanisms whereby tissue hypoxia may regulate apoptosis, inflammatory mediator expression and matrix regulation in human tenocytes. |
2012-02-21 |
2023-08-12 |
human |
| Ming-Hui Sun, Kuan-Jen Chen, Yeou-Ping Tsao, Ling-Yuh Kao, Wen-Hwa Han, Ken-Kuo Lin, Jong-Hwei Su Pan. Down-regulation of matrix metalloproteinase-9 by pyrrolidine dithiocarbamate prevented retinal ganglion cell death after transection of optic nerve in rats. Current eye research. vol 36. issue 11. 2012-02-14. PMID:21999230. |
to investigate the effects of pyrrolidine dithiocarbamate (pdtc), a nuclear factor κ-light-chain-enhancer of activated b cells (nf-κb) inhibitor, on the expression of matrix metalloproteinases (mmp) and mmp-mediated apoptosis in retinal ganglion cells (rgcs) following the transection of the optic nerve (on) in rats. |
2012-02-14 |
2023-08-12 |
rat |
| Molly A Taylor, Yong-Hun Lee, William P Schieman. Role of TGF-β and the tumor microenvironment during mammary tumorigenesis. Gene expression. vol 15. issue 3. 2012-02-09. PMID:22268294. |
transforming growth factor-beta (tgf-beta) is a multifunctional cytokine that functions to inhibit mammary tumorigenesis by directly inducing mammary epithelial cells (mecs) to undergo cell cycle arrest or apoptosis, and to secrete a variety of cytokines, growth factors, and extracellular matrix proteins that maintain cell and tissue homeostasis. |
2012-02-09 |
2023-08-12 |
Not clear |
| Patricia J Keel. Mechanisms by which the extracellular matrix and integrin signaling act to regulate the switch between tumor suppression and tumor promotion. Journal of mammary gland biology and neoplasia. vol 16. issue 3. 2012-02-07. PMID:21822945. |
signaling from fak moreover regulates p53 and mir-200 members, which control apoptosis and epithelial phenotype, such that a compliant matrix is predicted to promote normal mammary gland architecture and suppress tumor formation. |
2012-02-07 |
2023-08-12 |
Not clear |
| Qichang Zheng, Shanglong Liu, Zifang Son. Mechanism of arterial remodeling in chronic allograft vasculopathy. Frontiers of medicine. vol 5. issue 3. 2012-01-31. PMID:21964706. |
cav is characterized by concentric and diffuse neointimal formation, medial apoptosis, infiltration of lymphocyte or inflammatory cells, and deposition of extracellular matrix both in arteries and veins. |
2012-01-31 |
2023-08-12 |
Not clear |