| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ian M Nordon, Robert J Hinchliffe, Amir H Malkawi, Grisha Pirianov, Evelyn Torsney, Ian M Loftus, Gillian W Cockerill, Matt M Thompso. Comparative proteomics reveals a systemic vulnerability in the vasculature of patients with abdominal aortic aneurysms. Journal of vascular surgery. vol 54. issue 4. 2011-11-18. PMID:21741794. |
abdominal aortic aneurysms (aaa) are associated with inflammation, apoptosis, and matrix degradation. |
2011-11-18 |
2023-08-12 |
Not clear |
| Kinga Musiał, Danuta Zwolińsk. Matrix metalloproteinases and soluble Fas/FasL system as novel regulators of apoptosis in children and young adults on chronic dialysis. Apoptosis : an international journal on programmed cell death. vol 16. issue 7. 2011-11-15. PMID:21516345. |
matrix metalloproteinases and soluble fas/fasl system as novel regulators of apoptosis in children and young adults on chronic dialysis. |
2011-11-15 |
2023-08-12 |
human |
| Sarina Meinen, Shuo Lin, Raphael Thurnherr, Michael Erb, Thomas Meier, Markus A Rüeg. Apoptosis inhibitors and mini-agrin have additive benefits in congenital muscular dystrophy mice. EMBO molecular medicine. vol 3. issue 8. 2011-11-15. PMID:21674808. |
studies in mouse models have shown that transgenic expression of a designed, miniaturized form of the extracellular matrix molecule agrin ('mini-agrin') or apoptosis inhibition by either overexpression of bcl2 or application of the pharmacological substance omigapil can ameliorate the disease. |
2011-11-15 |
2023-08-12 |
mouse |
| Juliana Silva Zanetti, Danilo Fiqueredo Soave, João Paulo Oliveira-Costa, Giórgia Gobbi da Silveira, Leandra Náira Zambelli Ramalho, Sérgio Britto Garcia, Sérgio Zucoloto, Alfredo Ribeiro-Silv. The role of tumor hypoxia in MUC1-positive breast carcinomas. Virchows Archiv : an international journal of pathology. vol 459. issue 4. 2011-11-15. PMID:21892751. |
muc1 is involved in cell signaling, inhibition of cell-cell and cell matrix adhesion, apoptosis, proliferation, and transcription. |
2011-11-15 |
2023-08-12 |
Not clear |
| Pierre H Vacho. Integrin signaling, cell survival, and anoikis: distinctions, differences, and differentiation. Journal of signal transduction. vol 2011. 2011-11-10. PMID:21785723. |
the same complex nature applies to anoikis, a form of caspase-dependent apoptosis that is largely regulated by integrin-mediated, cell-extracellular matrix interactions. |
2011-11-10 |
2023-08-12 |
Not clear |
| Irina Surgucheva, Kumaravel Chidambaram, David A Willoughby, Andrei Surgucho. Matrix metalloproteinase 9 expression: new regulatory elements. Journal of ocular biology, diseases, and informatics. vol 3. issue 2. 2011-11-10. PMID:21818406. |
retinal ganglion cells apoptosis is linked to matrix metalloproteinase 9 (mmp-9) controlled changes of extracellular matrix. |
2011-11-10 |
2023-08-12 |
Not clear |
| Michal Cohen-Naftaly, Scott L Friedma. Current status of novel antifibrotic therapies in patients with chronic liver disease. Therapeutic advances in gastroenterology. vol 4. issue 6. 2011-11-10. PMID:22043231. |
the cascade starts with hepatocyte necrosis and apoptosis, which instigate inflammatory signaling by chemokines and cytokines, recruitment of immune cell populations, and activation of fibrogenic cells, culminating in the deposition of extracellular matrix. |
2011-11-10 |
2023-08-12 |
Not clear |
| Christopher K Kepler, D Greg Anderson, Chadi Tannoury, Ravi K Ponnappa. Intervertebral disk degeneration and emerging biologic treatments. The Journal of the American Academy of Orthopaedic Surgeons. vol 19. issue 9. 2011-11-02. PMID:21885700. |
acceleration of cellular senescence and apoptosis in degenerative ivds and the depletion of matrix proteins have prompted the development of treatments based on replacing ivd cells using various cell sources. |
2011-11-02 |
2023-08-12 |
Not clear |
| Jingjing Xu, Haiyi Liu, Yuanyuan Wu, Xun Gong, Qiong Zhou, Fuyuan Qia. Proapoptotic effect of metalloproteinase 9 secreted by trophoblasts on endothelial cells. The journal of obstetrics and gynaecology research. vol 37. issue 3. 2011-10-28. PMID:21159039. |
in this study, we investigate the involvement of matrix metalloproteinase 9 (mmp-9) in trophoblast-induced endothelial apoptosis. |
2011-10-28 |
2023-08-12 |
Not clear |
| Catherine M Shanahan, Matthew H Crouthamel, Alexander Kapustin, Cecilia M Giachell. Arterial calcification in chronic kidney disease: key roles for calcium and phosphate. Circulation research. vol 109. issue 6. 2011-10-27. PMID:21885837. |
in addition, we highlight recent findings indicating that elevated ca and p have direct effects on vascular smooth muscle cells (vsmcs) that promote vascular calcification, including stimulation of osteogenic/chondrogenic differentiation, vesicle release, apoptosis, loss of inhibitors, and extracellular matrix degradation. |
2011-10-27 |
2023-08-12 |
Not clear |
| Xiumei Wang, Wenjing Sun, Chengren Zhang, Guohua Ji, Yana Ge, Ye Xu, Yuzhen Zha. TGF-β1 inhibits the growth and metastasis of tongue squamous carcinoma cells through Smad4. Gene. vol 485. issue 2. 2011-10-24. PMID:21726607. |
transforming growth factor-β1 (tgf-β1) is a multifunctional cytokine that regulates cell growth, differentiation, migration, apoptosis and extracellular matrix remodeling. |
2011-10-24 |
2023-08-12 |
Not clear |
| Mark J Hoenerhoff, Arun R Pandiri, Stephanie A Lahousse, Hu-Hua Hong, Tai-Vu Ton, Tiwanda Masinde, Scott S Auerbach, Kevin Gerrish, Pierre R Bushel, Keith R Shockley, Shyamal D Peddada, Robert C Sill. Global gene profiling of spontaneous hepatocellular carcinoma in B6C3F1 mice: similarities in the molecular landscape with human liver cancer. Toxicologic pathology. vol 39. issue 4. 2011-10-14. PMID:21571946. |
using global gene expression profiling, we identify the dysregulation of several mediators similarly altered in human hcc, including re-expression of fetal oncogenes, upregulation of protooncogenes, downregulation of tumor suppressor genes, and abnormal expression of cell cycle mediators, growth factors, apoptosis regulators, and angiogenesis and extracellular matrix remodeling factors. |
2011-10-14 |
2023-08-12 |
mouse |
| Lynetta M Phillips, Ying Wang, Tiane Dai, David L Feldman, Janine LaPage, Sharon G Adle. The renin inhibitor aliskiren attenuates high-glucose induced extracellular matrix synthesis and prevents apoptosis in cultured podocytes. Nephron. Experimental nephrology. vol 118. issue 3. 2011-10-07. PMID:21228599. |
the renin inhibitor aliskiren attenuates high-glucose induced extracellular matrix synthesis and prevents apoptosis in cultured podocytes. |
2011-10-07 |
2023-08-12 |
Not clear |
| Lynetta M Phillips, Ying Wang, Tiane Dai, David L Feldman, Janine LaPage, Sharon G Adle. The renin inhibitor aliskiren attenuates high-glucose induced extracellular matrix synthesis and prevents apoptosis in cultured podocytes. Nephron. Experimental nephrology. vol 118. issue 3. 2011-10-07. PMID:21228599. |
altered extracellular matrix (ecm) remodeling and podocyte apoptosis are characteristic features of diabetic nephropathy (dn). |
2011-10-07 |
2023-08-12 |
Not clear |
| Olivier DE Wever, Joëlle Sobczak-Thépot, Anne-Sophie Vercoutter-Edouart, Jean-Claude Michalski, Radia Ouelaa-Benslama, Dwayne G Stupack, Marc Bracke, Jean Y J Wang, Christian Gespach, Shahin Emam. Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts. International journal of oncology. vol 39. issue 2. 2011-10-07. PMID:21567080. |
we have previously shown that the genotoxin-induced apoptosis in mouse embryo fibroblasts was enhanced by the extracellular matrix protein fibronectin (fn). |
2011-10-07 |
2023-08-12 |
mouse |
| Ning Liu, Jingwei Shang, Fengfeng Tian, Hiroyoshi Nishi, Koji Ab. In vivo optical imaging for evaluating the efficacy of edaravone after transient cerebral ischemia in mice. Brain research. vol 1397. 2011-10-06. PMID:21571257. |
in this study, we have conducted an in vivo optical imaging for detecting apoptosis and activation of matrix metalloproteinases (mmps), then evaluated the protective effect of 2 package types of free radical scavenger edaravone (a and b) on apoptosis, autophagy and nvu in mice after transient middle cerebral artery occlusion (tmcao). |
2011-10-06 |
2023-08-12 |
mouse |
| Justine Elliott, Nadezhda N Zheleznova, Patricia D Wilso. c-Src inactivation reduces renal epithelial cell-matrix adhesion, proliferation, and cyst formation. American journal of physiology. Cell physiology. vol 301. issue 2. 2011-10-03. PMID:21508333. |
increased activity of c-src has been associated with cell proliferation, matrix adhesion, motility, and apoptosis in tumors. |
2011-10-03 |
2023-08-12 |
mouse |
| Kohei Harada, Nao Hiramoto-Yamaki, Manabu Negishi, Hironori Kato. Ephexin4 and EphA2 mediate resistance to anoikis through RhoG and phosphatidylinositol 3-kinase. Experimental cell research. vol 317. issue 12. 2011-10-03. PMID:21621533. |
disruption of cell-extracellular matrix interaction causes epithelial cells to undergo apoptosis called anoikis, and resistance to anoikis has been suggested to be a critical step for cancer cells to metastasize. |
2011-10-03 |
2023-08-12 |
human |
| Ellen Neven, Tineke M De Schutter, Marc E De Broe, Patrick C D'Haes. Cell biological and physicochemical aspects of arterial calcification. Kidney international. vol 79. issue 11. 2011-09-13. PMID:21412217. |
as in bone formation, apoptosis and matrix vesicles play an important role in the initiation of vascular calcification. |
2011-09-13 |
2023-08-12 |
Not clear |
| Christiane Rüster, Gunter Wol. Angiotensin II as a morphogenic cytokine stimulating renal fibrogenesis. Journal of the American Society of Nephrology : JASN. vol 22. issue 7. 2011-09-12. PMID:21719784. |
many, but not all, of the stimulatory effects of ang ii on fibrogenesis depend on the induction of tgfβ and its downstream mediators of matrix accumulation, inflammation, and apoptosis. |
2011-09-12 |
2023-08-12 |
Not clear |