| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aiqun Wei, Bojiang Shen, Lisa Williams, Ashish Diwa. Mesenchymal stem cells: potential application in intervertebral disc regeneration. Translational pediatrics. vol 3. issue 2. 2016-02-02. PMID:26835326. |
degeneration of the intervertebral disc (ivd) is a major pathological process implicated in low back pain, which is characterized by cellular apoptosis and senescence with reduced synthesis of extracellular matrix (ecm). |
2016-02-02 |
2023-08-13 |
Not clear |
| Chia-Jung Liao, Hsiang-Cheng Chi, Chung-Ying Tsai, Chi-De Chen, Sheng-Ming Wu, Yi-Hsin Tseng, Yang-Hsiang Lin, I-Hsiao Chung, Ching-Ying Chen, Syuan-Ling Lin, Shiu-Feng Huang, Ya-Hui Huang, Kwang-Huei Li. A novel small-form NEDD4 regulates cell invasiveness and apoptosis to promote tumor metastasis. Oncotarget. vol 6. issue 11. 2016-01-29. PMID:25823820. |
overexpression of snedd4 increased the invasive ability of sk cells through upregulation of matrix metalloproteinase 9 and inhibited serum deprivation-induced apoptosis via upregulation of myeloid cell leukemia 1. |
2016-01-29 |
2023-08-13 |
mouse |
| Delphine Assent, Isabelle Bourgot, Benoît Hennuy, Pierre Geurts, Agnès Noël, Jean-Michel Foidart, Erik Maquo. A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells. PloS one. vol 10. issue 3. 2016-01-27. PMID:25774665. |
a membrane-type-1 matrix metalloproteinase (mt1-mmp)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells. |
2016-01-27 |
2023-08-13 |
human |
| Delphine Assent, Isabelle Bourgot, Benoît Hennuy, Pierre Geurts, Agnès Noël, Jean-Michel Foidart, Erik Maquo. A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells. PloS one. vol 10. issue 3. 2016-01-27. PMID:25774665. |
using this experimental model, we have previously demonstrated that membrane type-1 matrix metalloproteinase (mt1-mmp), a proteinase overexpressed in many aggressive tumours, promotes tumour progression by circumventing the collagen-induced up-regulation of bik, a pro-apoptotic tumour suppressor, and hence apoptosis. |
2016-01-27 |
2023-08-13 |
human |
| A C Reis, A L Alessandri, R M Athayde, D A Perez, J P Vago, T V Ávila, T P T Ferreira, A C S de Arantes, D de Sá Coutinho, M A Rachid, L P Sousa, M A Martins, G B Menezes, A G Rossi, M M Teixeira, V Pinh. Induction of eosinophil apoptosis by hydrogen peroxide promotes the resolution of allergic inflammation. Cell death & disease. vol 6. 2016-01-25. PMID:25675292. |
inflammatory cell numbers, cytokine and chemokine levels, mucus production, inflammatory cell apoptosis and peribronchiolar matrix deposition was quantified in the lungs. |
2016-01-25 |
2023-08-13 |
mouse |
| Meiyan Shi, Xiaodan He, Wei Wei, Juan Wang, Ti Zhang, Xiaohong She. Tenascin-C induces resistance to apoptosis in pancreatic cancer cell through activation of ERK/NF-κB pathway. Apoptosis : an international journal on programmed cell death. vol 20. issue 6. 2016-01-04. PMID:25690319. |
the present study indicated tnc in cellular matrix induces an activation of erk1/2/nf-κb/p65 signaling cascade and thereby mediates resistance to apoptosis in pancreatic cancer. |
2016-01-04 |
2023-08-13 |
human |
| Dalton Dittz, Cinthia Figueiredo, Fernanda O Lemos, Celso T R Viana, Silvia P Andrade, Elaine M Souza-Fagundes, Ricardo T Fujiwara, Carlos E Salas, Miriam T P Lope. Antiangiogenesis, loss of cell adhesion and apoptosis are involved in the antitumoral activity of Proteases from V. cundinamarcensis (C. candamarcensis) in murine melanoma B16F1. International journal of molecular sciences. vol 16. issue 4. 2016-01-04. PMID:25826531. |
in treated b16f1 cells, apoptosis was induced along with decreased cell binding to extracellular matrix components (ecm) and anchorage, without impairing viability. |
2016-01-04 |
2023-08-13 |
mouse |
| Xiaozhen Zhao, Zhenye Xu, Zhongqi Wang, Zhonghua Wu, Yabin Gong, Lijuan Zhou, Yi Xian. RNA silencing of integrin-linked kinase increases the sensitivity of the A549 lung cancer cell line to cisplatin and promotes its apoptosis. Molecular medicine reports. vol 12. issue 1. 2015-12-31. PMID:25760437. |
the increased cell apoptosis and proliferation inhibition were attributed to abnormal downstream protein expression of ilk, including phospho-glycogen synthase kinase 3β, p-akt, activator protein-1, β-catenin, cyclin d1 and matrix metalloproteinase-9. |
2015-12-31 |
2023-08-13 |
Not clear |
| Monika Barteková, Petra Šimončíková, Mária Fogarassyová, Monika Ivanová, Ľudmila Okruhlicová, Narcisa Tribulová, Ima Dovinová, Miroslav Barančí. Quercetin improves postischemic recovery of heart function in doxorubicin-treated rats and prevents doxorubicin-induced matrix metalloproteinase-2 activation and apoptosis induction. International journal of molecular sciences. vol 16. issue 4. 2015-12-28. PMID:25872140. |
quercetin improves postischemic recovery of heart function in doxorubicin-treated rats and prevents doxorubicin-induced matrix metalloproteinase-2 activation and apoptosis induction. |
2015-12-28 |
2023-08-13 |
rat |
| Monika Barteková, Petra Šimončíková, Mária Fogarassyová, Monika Ivanová, Ľudmila Okruhlicová, Narcisa Tribulová, Ima Dovinová, Miroslav Barančí. Quercetin improves postischemic recovery of heart function in doxorubicin-treated rats and prevents doxorubicin-induced matrix metalloproteinase-2 activation and apoptosis induction. International journal of molecular sciences. vol 16. issue 4. 2015-12-28. PMID:25872140. |
we focused on the ultrastructure of myocardium, matrix metalloproteinases (mmps), biometric parameters, and apoptosis induction. |
2015-12-28 |
2023-08-13 |
rat |
| Claire Marionnet, Cécile Pierrard, Christelle Golebiewski, Françoise Berner. Diversity of biological effects induced by longwave UVA rays (UVA1) in reconstructed skin. PloS one. vol 9. issue 8. 2015-12-18. PMID:25140898. |
uva1 also affected a wide panel of pathways and functions including cancer, proliferation, apoptosis and development, extracellular matrix and metabolism of lipids and glucose. |
2015-12-18 |
2023-08-13 |
human |
| Victoria L Herrera, Julius L Decano, Nicholas Giordano, Ann Marie Moran, Nelson Ruiz-Opaz. Aortic and carotid arterial stiffness and epigenetic regulator gene expression changes precede blood pressure rise in stroke-prone Dahl salt-sensitive hypertensive rats. PloS one. vol 9. issue 9. 2015-12-17. PMID:25229245. |
instead, differential gene induction was detected implicating molecular-functional changes in extracellular matrix (ecm) structural constituents, modifiers, cell adhesion, and matricellular proteins, as well as in endothelial function, apoptosis balance, and epigenetic regulators. |
2015-12-17 |
2023-08-13 |
rat |
| C C Yang, K J L Bur. Designing a tunable 3D heterocellular breast cancer tissue test system. Journal of tissue engineering and regenerative medicine. vol 9. issue 3. 2015-12-15. PMID:23307775. |
components and properties of the microenvironment such as extracellular matrix, adhesion integrins, tissue architectures and tissue modulus regulate growth, differentiation and apoptosis of cells. |
2015-12-15 |
2023-08-12 |
Not clear |
| Hui Pang, Bing Han, Tao Yu, Zhen Pen. The complex regulation of tanshinone IIA in rats with hypertension-induced left ventricular hypertrophy. PloS one. vol 9. issue 3. 2015-12-14. PMID:24647357. |
compared with the sham rats, the heart tissues of h-lvh (5%gs) group suffered severely from the oxidative damage, apoptosis of cardiomyocytes and extracellular matrix (ecm) deposition. |
2015-12-14 |
2023-08-12 |
rat |
| Pio Conti, Yazdami Shaik-Dasthagirisae. Atherosclerosis: a chronic inflammatory disease mediated by mast cells. Central-European journal of immunology. vol 40. issue 3. 2015-12-09. PMID:26648785. |
activated mast cells can have detrimental effects, provoking matrix degradation, apoptosis, and enhancement as well as recruitment of inflammatory cells, which actively contributes to atherosclerosis and plaque formation. |
2015-12-09 |
2023-08-13 |
Not clear |
| B H Yoo, O Masson, Y Li, I A Khan, P S Gowda, K V Rose. Anoikis of colon carcinoma cells triggered by β-catenin loss can be enhanced by tumor necrosis factor receptor 1 antagonists. Oncogene. vol 34. issue 38. 2015-12-07. PMID:25531320. |
detachment of non-malignant epithelial cells from the extracellular matrix causes their apoptosis, a phenomenon called anoikis. |
2015-12-07 |
2023-08-13 |
Not clear |
| Hafiz Ahmed, Dina M M AlSade. Galectin-3 as a Potential Target to Prevent Cancer Metastasis. Clinical Medicine Insights. Oncology. vol 9. 2015-12-07. PMID:26640395. |
interactions between two cells or between cell and extracellular matrix mediated by protein-carbohydrate interactions play pivotal roles in modulating various biological processes such as growth regulation, immune function, cancer metastasis, and apoptosis. |
2015-12-07 |
2023-08-13 |
Not clear |
| Heegyum Moon, Xuexiu Zheng, Tiing Jen Loh, Ha Na Jang, Yongchao Liu, Da-Woon Jung, Darren R Williams, Haihong She. Identification of Regulatory-RNAs for Alternative Splicing of Ron Proto-Oncogene. Journal of Cancer. vol 6. issue 12. 2015-12-07. PMID:26640595. |
ronΔ160 protein, which is produced by exclusion of exon 5 and 6, promotes cell migration, matrix invasion and protection from apoptosis. |
2015-12-07 |
2023-08-13 |
Not clear |
| Svenja Hartmann, Anne J Ridley, Susanne Lut. The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease. Frontiers in pharmacology. vol 6. 2015-12-04. PMID:26635606. |
rocks are involved in diverse cellular activities including actin cytoskeleton organization, cell adhesion and motility, proliferation and apoptosis, remodeling of the extracellular matrix and smooth muscle cell contraction. |
2015-12-04 |
2023-08-13 |
mouse |
| Sashko Spassov, Dietmar Pfeifer, Karl Strosing, Stefan Ryter, Matthias Hummel, Simone Faller, Alexander Hoetze. Genetic targets of hydrogen sulfide in ventilator-induced lung injury--a microarray study. PloS one. vol 9. issue 7. 2015-12-03. PMID:25025333. |
in contrast, ventilation with h2s activated genes involved in extracellular matrix remodelling, angiogenesis, inhibition of apoptosis, and inflammation. |
2015-12-03 |
2023-08-13 |
mouse |