| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Yang, Xiao-Hua Yu, Cheng Wang, Wen-Si He, Shu-Jun Zhang, Yi-Guo Yan, Jian Zhang, Yong-Xiao Xiang, Wen-Jun Wan. Interleukin-1β in intervertebral disk degeneration. Clinica chimica acta; international journal of clinical chemistry. vol 450. 2016-05-03. PMID:26341894. |
il-1β is highly expressed in degenerative intervertebral disk (ivd) tissues and cells, and it has been shown to be involved in multiple pathological processes during disk degeneration, including inflammatory responses, matrix destruction, angiogenesis and innervation, cellular apoptosis, oxidative stress and cellular senescence. |
2016-05-03 |
2023-08-13 |
Not clear |
| Thekkuttuparambil Ananthanarayanan Ajith, Ranimeno. Homocysteine in ocular diseases. Clinica chimica acta; international journal of clinical chemistry. vol 450. 2016-05-03. PMID:26343924. |
the molecular mechanism underlying these ocular diseases has been reported as impaired vascular endothelial function, apoptosis of retinal ganglion cells, extracellular matrix alterations, decreased lysyl oxidase activity and oxidative stress. |
2016-05-03 |
2023-08-13 |
human |
| Cheng Wang, Wen-Jun Wang, Yi-Guo Yan, Yong-Xiao Xiang, Jian Zhang, Zhi-Han Tang, Zhi-Sheng Jian. MicroRNAs: New players in intervertebral disc degeneration. Clinica chimica acta; international journal of clinical chemistry. vol 450. 2016-05-03. PMID:26368266. |
chronic low back pain is generally attributed to intervertebral disc (ivd) degeneration (idd), which is closely associated with apoptosis, extracellular matrix (ecm) disruption, cell proliferation and inflammatory response. |
2016-05-03 |
2023-08-13 |
human |
| Wojciech Miltyk, Arkadiusz Surazyński, Wołczyński Sławomir, Jerzy A Pałk. Combined therapy with disintegrin and melphalan as a new strategy in inhibition of endometrial cancer cell line (Ishikawa) growth. Folia histochemica et cytobiologica. vol 47. issue 5. 2016-04-22. PMID:20067882. |
decreased biosynthesis of collagen in extracellular matrix may suppress cell growth and induce apoptosis. |
2016-04-22 |
2023-08-12 |
Not clear |
| P Spitalieri, M C Quitadamo, A Orlandi, E Puxeddu, G Curradi, F Sangiuol. Human embryonic stem cells recover in vivo acute lung inflammation bleomycin-induced. Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. vol 30. issue 3. 2016-04-22. PMID:24284290. |
idiopathic pulmonary fibrosis (ipf) is characterized by alveolar epithelial cell injury, type ii cell activation, apoptosis and bronchiolar epithelial cell proliferation, accumulation of extracellular matrix and fibroblasts. |
2016-04-22 |
2023-08-12 |
mouse |
| Bethan Alice Monk, Sarah Jane Georg. The Effect of Ageing on Vascular Smooth Muscle Cell Behaviour--A Mini-Review. Gerontology. vol 61. issue 5. 2016-04-22. PMID:25471382. |
in this review, we discuss the effect of age on vsmc behaviour, proliferation, migration, apoptosis, inflammation, extracellular matrix synthesis and calcification. |
2016-04-22 |
2023-08-13 |
Not clear |
| Yuval Ramot, Arianna Mastrofrancesco, Emanuela Camera, Pierre Desreumaux, Ralf Paus, Mauro Picard. The role of PPARγ-mediated signalling in skin biology and pathology: new targets and opportunities for clinical dermatology. Experimental dermatology. vol 24. issue 4. 2016-04-22. PMID:25644500. |
overall, however, selected pparγ modulators appear to act as hair growth inhibitors that reduce the proliferation and promote apoptosis of hair matrix keratinocytes. |
2016-04-22 |
2023-08-13 |
human |
| A de P R Júnior, G M Dos Reis, K S F E Silva, D A Rodrigues, M C S Gomes, J V M Martins, I R da Costa, G A Freitas, K K V O Mour. Analysis of the GSTM1-null polymorphism in patients with pterygium from Goiânia, Goiás Brazil. Genetics and molecular research : GMR. vol 14. issue 2. 2016-04-21. PMID:26125818. |
many physical and biological factors are associated with the pathogenesis of pterygium, including heat, dust, and other particles in the atmosphere, and immunological mechanisms, mechanisms involving extracellular matrix reorganization, growth factors, cytokines, apoptosis, and angiogenesis. |
2016-04-21 |
2023-08-13 |
human |
| Mario Notari, Julián Pulecio, Ángel Ray. Update on the Pathogenic Implications and Clinical Potential of microRNAs in Cardiac Disease. BioMed research international. vol 2015. 2016-04-21. PMID:26221581. |
for instance, acute myocardial infarction induces cardiac tissue necrosis and apoptosis but also initiates a pathological remodelling response of the left ventricle that includes hypertrophic growth of cardiomyocytes and fibrotic deposition of extracellular matrix components. |
2016-04-21 |
2023-08-13 |
Not clear |
| David H McDaniel, Iltefat H Hamzavi, Joshua A Zeichner, Sabrina G Fabi, Vivian W Bucay, Julie C Harper, Jody A Comstock, Elizabeth T Makino, Rahul C Mehta, Virginia L Veg. Total Defense + Repair: A Novel Concept in Solar Protection and Skin Rejuvenation. Journal of drugs in dermatology : JDD. vol 14. issue 7. 2016-04-18. PMID:26151795. |
thus, ir-a radiation regulates hundreds of genes in skin, with roles in extracellular matrix (ecm) homeostasis regulation, apoptosis, cell growth, and stress responses. |
2016-04-18 |
2023-08-13 |
Not clear |
| Andre A M Torricelli, Abirami Santhanam, Jiahui Wu, Vivek Singh, Steven E Wilso. The corneal fibrosis response to epithelial-stromal injury. Experimental eye research. vol 142. 2016-04-18. PMID:26675407. |
transparency is subsequently restored when the ebm is completely regenerated, myofibroblasts are deprived of tgfβ and undergo apoptosis, and the keratocytes re-occupy the anterior stroma and reabsorb disordered extracellular matrix. |
2016-04-18 |
2023-08-13 |
Not clear |
| Zongduo Guo, Liang Xu, Xiaoying Wang, Xiaochuan Su. MMP-9 expression and activity is concurrent with endothelial cell apoptosis in the basilar artery after subarachnoid hemorrhaging in rats. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 36. issue 7. 2016-04-14. PMID:25627354. |
while several studies have shown the role of matrix metalloproteinase 9 in cerebral tissues and microvasculature after subarachnoid hemorrhage the role of matrix metalloproteinase 9 in large cerebral vasculature is limited, the present study aimed at investigating the relationship between the expression and activity of matrix metalloproteinase 9 and vascular endothelial cell apoptosis in the basilar artery at early-stage post-subarachnoid hemorrhaging in rats. |
2016-04-14 |
2023-08-13 |
rat |
| Joshua T Mattila, Pauline Maiello, Tao Sun, Laura E Via, JoAnne L Flyn. Granzyme B-expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques. Cellular microbiology. vol 17. issue 8. 2016-04-14. PMID:25653138. |
purified grzb was not bactericidal or bacteriostatic, suggesting secreted neutrophil grzb acts on extracellular targets, potentially enhancing neutrophil migration through extracellular matrix and regulating apoptosis or activation in other cell types. |
2016-04-14 |
2023-08-13 |
human |
| Guobao Chen, Yonggang L. Immobilization and Application of Electrospun Nanofiber Scaffold-based Growth Factor in Bone Tissue Engineering. Current pharmaceutical design. vol 21. issue 15. 2016-04-08. PMID:25732663. |
in bone tissue engineering, growth factors are expected to transmit signals that stimulate cellular proliferation, migration, differentiation, metabolism, apoptosis and extracellular matrix (ecm) deposition. |
2016-04-08 |
2023-08-13 |
Not clear |
| Li Ying, Ziwei Zhu, Zhiyun Xu, Tianrui He, Encheng Li, Zhe Guo, Fen Liu, Chunmeng Jiang, Qi Wan. Cancer Associated Fibroblast-Derived Hepatocyte Growth Factor Inhibits the Paclitaxel-Induced Apoptosis of Lung Cancer A549 Cells by Up-Regulating the PI3K/Akt and GRP78 Signaling on a Microfluidic Platform. PloS one. vol 10. issue 6. 2016-04-06. PMID:26115510. |
moreover, treatment with the caf matrix inhibited spontaneous and medium or high dose of paclitaxel-induced a549 cell apoptosis. |
2016-04-06 |
2023-08-13 |
Not clear |
| Li Ying, Ziwei Zhu, Zhiyun Xu, Tianrui He, Encheng Li, Zhe Guo, Fen Liu, Chunmeng Jiang, Qi Wan. Cancer Associated Fibroblast-Derived Hepatocyte Growth Factor Inhibits the Paclitaxel-Induced Apoptosis of Lung Cancer A549 Cells by Up-Regulating the PI3K/Akt and GRP78 Signaling on a Microfluidic Platform. PloS one. vol 10. issue 6. 2016-04-06. PMID:26115510. |
our data indicated that hgf in the caf matrix activated the met/pi3k/akt and up-regulated grp78 expression, promoting chemoresistance to paclitaxel-mediated apoptosis in a549 cells. |
2016-04-06 |
2023-08-13 |
Not clear |
| Jingyin Yan, Zhengmao Zhang, Jun Yang, William E Mitch, Yanlin Wan. JAK3/STAT6 Stimulates Bone Marrow-Derived Fibroblast Activation in Renal Fibrosis. Journal of the American Society of Nephrology : JASN. vol 26. issue 12. 2016-03-28. PMID:26032813. |
treatment with cp690,550 also significantly reduced myofibroblast transformation, matrix protein expression, fibrosis development, and apoptosis in obstructed kidneys. |
2016-03-28 |
2023-08-13 |
mouse |
| Zoi Piperigkou, Konstantina Karamanou, Nikolaos A Afratis, Panagiotis Bouris, Chrysostomi Gialeli, Celso L R Belmiro, Mauro S G Pavão, Dimitrios H Vynios, Aristidis M Tsatsaki. Biochemical and toxicological evaluation of nano-heparins in cell functional properties, proteasome activation and expression of key matrix molecules. Toxicology letters. vol 240. issue 1. 2016-03-28. PMID:26476401. |
we determined whether these nano-heparins are able to affect cell proliferation, apoptosis and invasion, as well as proteasome activity and the expression of extracellular matrix molecules. |
2016-03-28 |
2023-08-13 |
Not clear |
| Zoi Piperigkou, Konstantina Karamanou, Nikolaos A Afratis, Panagiotis Bouris, Chrysostomi Gialeli, Celso L R Belmiro, Mauro S G Pavão, Dimitrios H Vynios, Aristidis M Tsatsaki. Biochemical and toxicological evaluation of nano-heparins in cell functional properties, proteasome activation and expression of key matrix molecules. Toxicology letters. vol 240. issue 1. 2016-03-28. PMID:26476401. |
moreover, nano-styela regulates cell apoptosis, expression of inflammatory molecules, such as il-6 and il-8 and reduces the expression levels of extracellular matrix macromolecules, such as the proteolytic enzymes mt1-mmp, upa and the cell surface proteoglycans syndecan-1 and -2, but not on syndecan-4. |
2016-03-28 |
2023-08-13 |
Not clear |
| Mojtaba Parvizi, Martin C Harmse. Therapeutic Prospect of Adipose-Derived Stromal Cells for the Treatment of Abdominal Aortic Aneurysm. Stem cells and development. vol 24. issue 13. 2016-03-24. PMID:25706330. |
in general, pathological features of aaa include inflammation, degradation of the extracellular matrix (ecm), and smooth muscle cell apoptosis. |
2016-03-24 |
2023-08-13 |
Not clear |