| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Philipp J Albert, Ulrich S Schwar. Dynamics of Cell Ensembles on Adhesive Micropatterns: Bridging the Gap between Single Cell Spreading and Collective Cell Migration. PLoS computational biology. vol 12. issue 4. 2016-08-15. PMID:27054883. |
the collective dynamics of multicellular systems arise from the interplay of a few fundamental elements: growth, division and apoptosis of single cells; their mechanical and adhesive interactions with neighboring cells and the extracellular matrix; and the tendency of polarized cells to move. |
2016-08-15 |
2023-08-13 |
Not clear |
| Chun-Ling Dong, Hao-Zhi Liu, Zhen-Chun Zhang, Huan-Li Zhao, Hui Zhao, Yan Huang, Jian-Hua Yao, Tian-Sheng Su. The influence of MicroRNA-150 in Osteoblast Matrix Mineralization. Journal of cellular biochemistry. vol 116. issue 12. 2016-08-09. PMID:26212040. |
matrix mineralization was detected by alizarin red s (ars) staining and flow cytometry was employed to quantify apoptosis in each group. |
2016-08-09 |
2023-08-13 |
mouse |
| Andreas Koch, Sven Arke Lang, Peter Johannes Wild, Susanne Gantner, Abdo Mahli, Gerrit Spanier, Mark Berneburg, Martina Müller, Anja Katrin Bosserhoff, Claus Hellerbran. Glucose transporter isoform 1 expression enhances metastasis of malignant melanoma cells. Oncotarget. vol 6. issue 32. 2016-08-09. PMID:26293674. |
glut1 suppressed melanoma cells revealed significantly reduced proliferation, apoptosis resistance, migratory activity and matrix metalloproteinase 2 (mmp2) expression. |
2016-08-09 |
2023-08-13 |
human |
| Jennifer Zieba, Kimberly Nicole Forlenza, Jagteshwar Singh Khatra, Anna Sarukhanov, Ivan Duran, Diana Rigueur, Karen M Lyons, Daniel H Cohn, Amy E Merrill, Deborah Krako. TGFβ and BMP Dependent Cell Fate Changes Due to Loss of Filamin B Produces Disc Degeneration and Progressive Vertebral Fusions. PLoS genetics. vol 12. issue 3. 2016-08-08. PMID:27019229. |
this change is characterized by hallmarks of endochondral-like ossification including alterations in collagen matrix, expression of collagen x, increased apoptosis, and inappropriate ossification of the disc tissue. |
2016-08-08 |
2023-08-13 |
mouse |
| Aaron H Morris, Julie Chang, Themis R Kyriakide. Inadequate Processing of Decellularized Dermal Matrix Reduces Cell Viability In Vitro and Increases Apoptosis and Acute Inflammation In Vivo. BioResearch open access. vol 5. issue 1. 2016-08-08. PMID:27500014. |
inadequate processing of decellularized dermal matrix reduces cell viability in vitro and increases apoptosis and acute inflammation in vivo. |
2016-08-08 |
2023-08-13 |
mouse |
| Guoliang Zhang, Yanhong Sun, Yuewen Wang, Rui Liu, Yimin Bao, Qi L. MiR-502-5p inhibits IL-1β-induced chondrocyte injury by targeting TRAF2. Cellular immunology. vol 302. 2016-07-28. PMID:26861148. |
mir-502-5p overexpression inhibited il-1β-induced reduction in cell viability and increase in cell apoptosis, and alleviated il-1β-induced extracellular matrix (ecm) metabolic imbalance and pro-inflammatory cytokine production. |
2016-07-28 |
2023-08-13 |
Not clear |
| Seiko Yoshino, Toshiro Hara, Hiroki J Nakaoka, Akane Kanamori, Yoshinori Murakami, Motoharu Seiki, Takeharu Sakamot. The ERK signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux. Cell discovery. vol 2. 2016-07-27. PMID:27462466. |
loss of anchorage to the extracellular matrix leads to apoptosis (anoikis) in normal cells, but cancerous cells are usually resistant to such stress. |
2016-07-27 |
2023-08-13 |
mouse |
| Matthew R Zeglinski, Jared J L Davies, Saeid Ghavami, Sunil G Rattan, Andrew J Halayko, Ian M C Dixo. Chronic expression of Ski induces apoptosis and represses autophagy in cardiac myofibroblasts. Biochimica et biophysica acta. vol 1863. issue 6 Pt A. 2016-07-19. PMID:27039037. |
as myofibroblasts are the sole mediators of matrix expansion in heart failure, we suggest that ski, or a putative ski-mimetic, may induce graded apoptosis in myofibroblasts within the failing heart and may be a novel therapeutic approach towards controlling cardiac fibrosis. |
2016-07-19 |
2023-08-13 |
rat |
| Zhaohong Wang, Huilin Yan. EMMPRIN, SP1 and microRNA-27a mediate physcion 8-O-β-glucopyranoside-induced apoptosis in osteosarcoma cells. American journal of cancer research. vol 6. issue 6. 2016-07-19. PMID:27429847. |
in addition, physcion treatment significantly inhibited extracellular matrix metalloproteinase inducer (emmprin) expression in mg-63 cells, in a dose-dependent manner; meanwhile, emmprin protein overexpression markedly reduced pg-induced apoptosis. |
2016-07-19 |
2023-08-13 |
human |
| Min Long, Montserrat Rojo de la Vega, Qing Wen, Manish Bharara, Tao Jiang, Rui Zhang, Shiwen Zhou, Pak K Wong, Georg T Wondrak, Hongting Zheng, Donna D Zhan. An Essential Role of NRF2 in Diabetic Wound Healing. Diabetes. vol 65. issue 3. 2016-07-06. PMID:26718502. |
in a streptozotocin-induced diabetes mouse model, nrf2(-/-) mice have delayed wound closure rates compared with nrf2(+/+) mice, which is, at least partially, due to greater oxidative dna damage, low transforming growth factor-β1 (tgf-β1) and high matrix metalloproteinase 9 (mmp9) expression, and increased apoptosis. |
2016-07-06 |
2023-08-13 |
mouse |
| Monica Di Giacomo, Antonella Camaioni, Francesca G Klinger, Rita Bonfiglio, Antonietta Salustr. Cyclic AMP-elevating Agents Promote Cumulus Cell Survival and Hyaluronan Matrix Stability, Thereby Prolonging the Time of Mouse Oocyte Fertilizability. The Journal of biological chemistry. vol 291. issue 8. 2016-07-01. PMID:26694612. |
cumulus cell apoptosis and matrix disassembly also occurred in ovulated cocs cultured in vitro. |
2016-07-01 |
2023-08-13 |
mouse |
| Torsten Lowin, Rainer H Strau. Synovial fibroblasts integrate inflammatory and neuroendocrine stimuli to drive rheumatoid arthritis. Expert review of clinical immunology. vol 11. issue 10. 2016-06-30. PMID:26163397. |
these changes manifest in resistance to fas-induced apoptosis and production of cytokines, chemokines and matrix metalloproteinases. |
2016-06-30 |
2023-08-13 |
Not clear |
| Jingwei Li, Kailei Jiang, Fujie Zha. Oxymatrine suppresses proliferation and facilitates apoptosis of human ovarian cancer cells through upregulating microRNA‑29b and downregulating matrix metalloproteinase‑2 expression. Molecular medicine reports. vol 12. issue 4. 2016-06-27. PMID:26099492. |
oxymatrine suppresses proliferation and facilitates apoptosis of human ovarian cancer cells through upregulating microrna‑29b and downregulating matrix metalloproteinase‑2 expression. |
2016-06-27 |
2023-08-13 |
human |
| Byong Hoon Yoo, Anna Zagryazhskaya, Yongling Li, Ananda Koomson, Iman Aftab Khan, Takehiko Sasazuki, Senji Shirasawa, Kirill V Rose. Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells. Autophagy. vol 11. issue 8. 2016-06-20. PMID:26061804. |
upregulation of atg3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells. |
2016-06-20 |
2023-08-13 |
Not clear |
| Byong Hoon Yoo, Anna Zagryazhskaya, Yongling Li, Ananda Koomson, Iman Aftab Khan, Takehiko Sasazuki, Senji Shirasawa, Kirill V Rose. Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells. Autophagy. vol 11. issue 8. 2016-06-20. PMID:26061804. |
detachment of nonmalignant intestinal epithelial cells from the extracellular matrix (ecm) triggers their growth arrest and, ultimately, apoptosis. |
2016-06-20 |
2023-08-13 |
Not clear |
| b' Alberto Izzotti, Chiara Ceccaroli, Maria G Longobardi, Rosanna T Micale, Alessandra Pulliero, Sebastiano La Maestra, Sergio C Sacc\\xc3\\xa. Molecular Damage in Glaucoma: from Anterior to Posterior Eye Segment. The MicroRNA Role. MicroRNA (Shariqah, United Arab Emirates). vol 4. issue 1. 2016-06-17. PMID:26149270.' |
released micrornas include mir-21 (apoptosis), mir-450 (cell aging, maintenance of contractile tone), mir-107 (nestin expression, apoptosis), mir-149 (endothelia and extracellular matrix homeostasis). |
2016-06-17 |
2023-08-13 |
Not clear |
| Christoph Meyer, Roman Liebe, Katja Breitkopf-Heinlein, Yan Liu, Alexandra Müller, Pia Rakoczy, Maria Thomas, Honglei Weng, Anastasia Bachmann, Matthias Ebert, Steven Doole. Hepatocyte fate upon TGF-β challenge is determined by the matrix environment. Differentiation; research in biological diversity. vol 89. issue 5. 2016-06-14. PMID:25982745. |
upon tgf-β challenge, hepatocytes either undergo an epithelial to mesenchymal transition (emt) or apoptosis: culture on stiff collagen (monolayer) results in emt whereas hepatocytes in a soft collagen matrix (sandwich) undergo programmed cell death. |
2016-06-14 |
2023-08-13 |
Not clear |
| Sandra Chrusciel, Maéva Zysman, Philippe Caramelle, Arnaud Tiendrebeogo, Indoumady Baskara, Sabine Le Gouvello, François Chabot, Stéphane Giraudier, Jorge Boczkowski, Laurent Boye. Lack of Transcription Factor p53 Exacerbates Elastase-Induced Emphysema in Mice. American journal of respiratory cell and molecular biology. vol 54. issue 2. 2016-06-14. PMID:26106979. |
we quantified emphysema (morphometric analysis), chemokine (c-c motif) ligand 2 (ccl2), and tnf-α in bronchoalveolar lavage (bal) (elisa), oxidative stress markers [heme oxygenase 1 (ho1), nad(p)h dehydrogenase quinone 1 (nqo1), and quantitative rt-pcr], matrix metalloproteinase 12 (mmp12) expression, and macrophage apoptosis (cleaved caspase-3, immunofluorescence). |
2016-06-14 |
2023-08-13 |
mouse |
| Fares Zeidán-Chuliá, Mervi Gürsoy, Ben-Hur Neves de Oliveira, Vural Özdemir, Eija Könönen, Ulvi K Gürso. A Systems Biology Approach to Reveal Putative Host-Derived Biomarkers of Periodontitis by Network Topology Characterization of MMP-REDOX/NO and Apoptosis Integrated Pathways. Frontiers in cellular and infection microbiology. vol 5. 2016-06-14. PMID:26793622. |
by using systems biology tools, we aimed to (1) identify an integrated interactome between matrix metalloproteinase (mmp)-redox/nitric oxide (no) and apoptosis upstream pathways of periodontal inflammation, and (2) characterize the attendant topological network properties to uncover putative biomarkers to be tested in saliva from patients with periodontitis. |
2016-06-14 |
2023-08-13 |
Not clear |
| Dominique Muschter, Nicole Schäfer, Hubert Stangl, Rainer H Straub, Susanne Grässe. Sympathetic Neurotransmitters Modulate Osteoclastogenesis and Osteoclast Activity in the Context of Collagen-Induced Arthritis. PloS one. vol 10. issue 10. 2016-06-08. PMID:26431344. |
therefore, bmms from dark agouti rats at different cia stages were differentiated into osteoclasts in vitro and osteoclast number, cathepsin k activity, matrix resorption and apoptosis were analyzed in the presence of acetylcholine (ach), noradrenaline (na) vasoactive intestinal peptide (vip) and assay-dependent, adenylyl cyclase activator nkh477. |
2016-06-08 |
2023-08-13 |
rat |