| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shaofeng An, Yan Gao, Yihua Huang, Xiaoqiong Jiang, Ke Ma, Junqi Lin. Short-term effects of calcium ions on the apoptosis and onset of mineralization of human dental pulp cells in vitro and in vivo. International journal of molecular medicine. vol 36. issue 1. 2016-03-24. PMID:25999211. |
the results showed that 5.4 and 9.0 mm ca2+ accelerated the onset of mineralized matrix nodule formation, promoted osteopontin mrna expression and induced marked cell apoptosis and necrosis, but had no obvious effect on cell proliferation. |
2016-03-24 |
2023-08-13 |
human |
| Ningning He, Yang Xu, Wei Du, Xin Qi, Lu Liang, Yuebing Wang, Guowei Feng, Yan Fan, Zhongchao Han, Deling Kong, Zhen Cheng, Joseph C Wu, Zuoxiang He, Zongjin L. Extracellular Matrix can Recover the Downregulation of Adhesion Molecules after Cell Detachment and Enhance Endothelial Cell Engraftment. Scientific reports. vol 5. 2016-03-24. PMID:26039874. |
we demonstrated that cell detachment can cause downregulation of cell adhesion and extracellular matrix (ecm) molecules, but no obvious cell anoikis, a form of apoptosis after cell detachment, was observed. |
2016-03-24 |
2023-08-13 |
mouse |
| Valérian Bunel, Marie-Hélène Antoine, Joëlle Nortier, Pierre Duez, Caroline Stévign. Nephroprotective effects of ferulic acid, Z-ligustilide and E-ligustilide isolated from Angelica sinensis against cisplatin toxicity in vitro. Toxicology in vitro : an international journal published in association with BIBRA. vol 29. issue 3. 2016-03-21. PMID:25561245. |
five phenomena involved in acute kidney injury and subsequent fibrosis were investigated: (i) modulation of cell survival via reduction of the apoptosis rate; (ii) reduction of oxidative stress; (iii) improvement of tubular regeneration capacities through proliferation and migration; (iv) limitation of extracellular matrix and collagen deposition; and (v) prevention of the dedifferentiation processes via the β-catenin pathway. |
2016-03-21 |
2023-08-13 |
Not clear |
| Ellen K Quarles, Dao-Fu Dai, Autumn Tocchi, Nathan Basisty, Lemuel Gitari, Peter S Rabinovitc. Quality control systems in cardiac aging. Ageing research reviews. vol 23. issue Pt A. 2016-03-21. PMID:25702865. |
these mechanisms include autophagy, ubiquitin-mediated turnover, apoptosis, mitochondrial quality control and cardiac matrix homeostasis. |
2016-03-21 |
2023-08-13 |
Not clear |
| Eleftheria Barlaka, Anikó Görbe, Renáta Gáspár, János Pálóczi, Péter Ferdinandy, Antigone Lazo. Activation of PPARβ/δ protects cardiac myocytes from oxidative stress-induced apoptosis by suppressing generation of reactive oxygen/nitrogen species and expression of matrix metalloproteinases. Pharmacological research. vol 95-96. 2016-03-21. PMID:25828396. |
activation of pparβ/δ protects cardiac myocytes from oxidative stress-induced apoptosis by suppressing generation of reactive oxygen/nitrogen species and expression of matrix metalloproteinases. |
2016-03-21 |
2023-08-13 |
rat |
| Jun Tashiro, Sharon J Elliot, David J Gerth, Xiaomei Xia, Simone Pereira-Simon, Rhea Choi, Paola Catanuto, Shahriar Shahzeidi, Rebecca L Toonkel, Rahil H Shah, Fadi El Salem, Marilyn K Glassber. Therapeutic benefits of young, but not old, adipose-derived mesenchymal stem cells in a chronic mouse model of bleomycin-induced pulmonary fibrosis. Translational research : the journal of laboratory and clinical medicine. vol 166. issue 6. 2016-03-21. PMID:26432923. |
lung tissue from aged blm mice receiving young ascs exhibited decreased fibrosis, matrix metalloproteinase (mmp)-2 activity, oxidative stress, and markers of apoptosis vs blm controls. |
2016-03-21 |
2023-08-13 |
mouse |
| Yange Ma, Airong Shen, Canyu Li, Shengnan Xu, Huanhuan Guo, Shunhong Zo. [Targeted interruption of COX-2 gene by siRNA inhibits the expression of VEGF, MMP-9, the activity of COX-2 and stimulates the apoptosis in eutopic, ectopic endometrial stromal cells of women with endometriosis]. Zhonghua fu chan ke za zhi. vol 50. issue 10. 2016-03-16. PMID:26675577. |
to investigate the effect of targeted interruption of cyclooxygenase-2 (cox-2) gene by small interference rna (sirna) on the expression of cox-2, vascular endothelial growth factor (vegf) and matrix metalloproteinase-9 (mmp-9) in eutopic and ectopic endometrial stromal cells (esc) with endometriosis, and the effect on the content of 6-keto-prostaglandin-f1α (6-keto-pgf1α, metabolites of cox) and the apoptosis of eutopic and ectopic esc with endometriosis. |
2016-03-16 |
2023-08-13 |
Not clear |
| Ana Cristina Lira Sobral, Victor Moreschi Neto, Gabriela Traiano, Ana Paula Percicote, Elizabeth Schneider Gugelmin, Cleber Machado de Souza, Lia Nakao, Luiz Fernando Bleggi Torres, Lucia de Noronh. Immunohistochemical expression of sulfhydryl oxidase (QSOX1) in pediatric medulloblastomas. Diagnostic pathology. vol 10. 2016-03-14. PMID:25908093. |
qsox1, whose functions include formation of disulphide bridges, which are needed for correct protein folding and stability, formation of the extracellular matrix, regulation of the redox status and cell cycle control, appears to be involved in apoptosis in pathological states such as cancer. |
2016-03-14 |
2023-08-13 |
Not clear |
| Daniela Kraljevic, Katarina Vukojevic, Dragana Karan, Borko Rajic, Jelena Todorovic, Josip Miskovic, Vajdana Tomic, Mario Kordic, Violeta Solji. Proliferation, apoptosis and expression of matrix metalloproteinase-9 in human fetal lung. Acta histochemica. vol 117. issue 4-5. 2016-03-10. PMID:25722035. |
proliferation, apoptosis and expression of matrix metalloproteinase-9 in human fetal lung. |
2016-03-10 |
2023-08-13 |
human |
| Weihua Li, Zhonghua Qi, Zhenqing Wei, Siwei Liu, Pin Wang, Yanwei Chen, Yongshun Zha. Paeoniflorin inhibits proliferation and induces apoptosis of human glioma cells via microRNA-16 upregulation and matrix metalloproteinase-9 downregulation. Molecular medicine reports. vol 12. issue 2. 2016-03-10. PMID:25954855. |
paeoniflorin inhibits proliferation and induces apoptosis of human glioma cells via microrna-16 upregulation and matrix metalloproteinase-9 downregulation. |
2016-03-10 |
2023-08-13 |
human |
| Jianheng Zhou, Jiumao Lin, Liya Liu, Yuqing Zheng, Zhenfeng Hon. Qianliening capsules influence the apoptosis of benign prostatic hyperplasia epithelial-1 cells by regulating the extracellular matrix. Molecular medicine reports. vol 11. issue 5. 2016-03-04. PMID:25592406. |
qianliening capsules influence the apoptosis of benign prostatic hyperplasia epithelial-1 cells by regulating the extracellular matrix. |
2016-03-04 |
2023-08-13 |
Not clear |
| Jianheng Zhou, Jiumao Lin, Liya Liu, Yuqing Zheng, Zhenfeng Hon. Qianliening capsules influence the apoptosis of benign prostatic hyperplasia epithelial-1 cells by regulating the extracellular matrix. Molecular medicine reports. vol 11. issue 5. 2016-03-04. PMID:25592406. |
the present study investigated whether qianliening capsules (qc) affected the apoptosis of benign prostatic hyperplastia epithelial (bph‑1) cells by regulating the extracellular matrix (ecm). |
2016-03-04 |
2023-08-13 |
Not clear |
| Jianheng Zhou, Jiumao Lin, Liya Liu, Yuqing Zheng, Zhenfeng Hon. Qianliening capsules influence the apoptosis of benign prostatic hyperplasia epithelial-1 cells by regulating the extracellular matrix. Molecular medicine reports. vol 11. issue 5. 2016-03-04. PMID:25592406. |
therefore, one of the mechanisms underlying the anti‑bph action of qc involves promoting apoptosis by regulating the expression of the extracellular matrix. |
2016-03-04 |
2023-08-13 |
Not clear |
| Li Li, Xiang Li, Erlinda The, Li-Jie Wang, Tian-You Yuan, Shi-Yi Wang, Jing Feng, Jing Wang, Yuan Liu, Ya-Han Wu, Xiu-E Ma, Jin Ge, Ying-Yu Cui, Xiao-Yan Jian. Low expression of lncRNA-GAS5 is implicated in human primary varicose great saphenous veins. PloS one. vol 10. issue 3. 2016-03-04. PMID:25806802. |
the cellular mechanisms of primary varicose great saphenous veins (gsvs) involve inflammation, apoptosis, and proliferation of local cells and extracellular matrix degradation. |
2016-03-04 |
2023-08-13 |
human |
| Andrew Filer, Philipp Antczak, Greg N Parsonage, Holly M Legault, Margot O'Toole, Mark J Pearson, Andrew M Thomas, Dagmar Scheel-Toellner, Karim Raza, Christopher D Buckley, Francesco Falcian. Stromal transcriptional profiles reveal hierarchies of anatomical site, serum response and disease and identify disease specific pathways. PloS one. vol 10. issue 3. 2016-03-04. PMID:25807374. |
we have demonstrated that fibroblast serum response signatures define disease at the tissue level, and that an oa specific, serum dependent repression of genes involved in cell adhesion, extracellular matrix remodelling and apoptosis is a critical discriminator between cultured oa and ra synovial fibroblasts. |
2016-03-04 |
2023-08-13 |
Not clear |
| Xiaoshuang Zhou, Chen Wang, Jihua Tian, Yanhong Wang, Yafeng Li, Zhaoyong Hu, Rongshan L. Mitogen-activated protein kinase mediates mevalonate-stimulated human mesangial cell proliferation. Molecular medicine reports. vol 12. issue 2. 2016-03-04. PMID:25936991. |
to investigate the role of mva in hmc proliferation, apoptosis, cell cycle and accumulation of extracellular matrix (ecm), the effects of mva on hmcs at different durations and at various doses were evaluated. |
2016-03-04 |
2023-08-13 |
human |
| Julhiany de Fátima da Silva, Juliana Vicentim, Haroldo Cesar de Oliveira, Caroline Maria Marcos, Patricia Akemi Assato, Patrícia Ferrari Andreotti, Juliana Leal Monteiro da Silva, Christiane Pienna Soares, Gil Benard, Ana Marisa Fusco Almeida, Maria José Soares Mendes-Giannin. Influence of the Paracoccidioides brasiliensis 14-3-3 and gp43 proteins on the induction of apoptosis in A549 epithelial cells. Memorias do Instituto Oswaldo Cruz. vol 110. issue 4. 2016-03-04. PMID:26038961. |
thus, this study evaluated the contribution of two p. brasiliensis molecules, the 14-3-3 and glycoprotein of 43 kda proteins, which had been previously described as extracellular matrix adhesins and apoptosis inductors in human pneumocytes. |
2016-03-04 |
2023-08-13 |
human |
| Dmitry L Aminin, Ekaterina S Menchinskaya, Evgeny A Pisliagin, Alexandra S Silchenko, Sergey A Avilov, Vladimir I Kalini. Anticancer activity of sea cucumber triterpene glycosides. Marine drugs. vol 13. issue 3. 2016-03-03. PMID:25756523. |
the anticancer molecular mechanisms include the induction of tumor cell apoptosis through the activation of intracellular caspase cell death pathways, arrest of the cell cycle at s or g2/m phases, influence on nuclear factors, nf-κb, and up-down regulation of certain cellular receptors and enzymes participating in cancerogenesis, such as egfr (epidermal growth factor receptor), akt (protein kinase b), erk (extracellular signal-regulated kinases), fak (focal adhesion kinase), mmp-9 (matrix metalloproteinase-9) and others. |
2016-03-03 |
2023-08-13 |
human |
| J Furuzawa-Carballeda, D Aguilar-León, A Gamboa-Domínguez, M A Valdovinos, C Nuñez-Álvarez, L A Martín-del-Campo, A B Enríquez, E Coss-Adame, A E Svarch, A Flores-Nájera, A Villa-Baños, J C Ceballos, G Torres-Villalobo. Achalasia--An Autoimmune Inflammatory Disease: A Cross-Sectional Study. Journal of immunology research. vol 2015. 2016-03-03. PMID:26078981. |
achalasia tissue exhibited an increase in the expression of proteins involved in extracellular matrix turnover, apoptosis, proinflammatory and profibrogenic cytokines, and tregs and bregs versus controls (p < 0.001). |
2016-03-03 |
2023-08-13 |
Not clear |
| Ioannis Andreou, Antonios P Antoniadis, Koki Shishido, Michail I Papafaklis, Konstantinos C Koskinas, Yiannis S Chatzizisis, Ahmet U Coskun, Elazer R Edelman, Charles L Feldman, Peter H Ston. How do we prevent the vulnerable atherosclerotic plaque from rupturing? Insights from in vivo assessments of plaque, vascular remodeling, and local endothelial shear stress. Journal of cardiovascular pharmacology and therapeutics. vol 20. issue 3. 2016-03-01. PMID:25336461. |
specifically, low ess augments lipid uptake and catabolism, induces plaque inflammation and oxidation, downregulates the production, upregulates the degradation of extracellular matrix, and increases cellular apoptosis ultimately leading to thin-cap fibroatheromas and/or endothelial erosions. |
2016-03-01 |
2023-08-13 |
Not clear |