| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andreas S Barth, Gordon F Tomasell. Gene scanning and heart attack risk. Trends in cardiovascular medicine. vol 26. issue 3. 2016-12-15. PMID:26277204. |
additional clusters were significantly enriched for pathways, which play prominent roles during ami and the development of atherosclerotic plaques in vascular tissue, including focal adhesion/extracellular matrix interaction, tgf-β signaling, apoptosis, regulation of vascular smooth muscle contraction, angiogenesis, calcium ion binding, and transcription factors. |
2016-12-15 |
2023-08-13 |
Not clear |
| Tu Hu, Qiuting You, Dan Chen, Jianbin Tong, Lei Shang, Jia Luo, Yi Qiu, Huimin Yu, Leping Zeng, Jufang Huan. Inhibiting Matrix Metalloproteinase 3 Ameliorates Neuronal Loss in the Ganglion Cell Layer of Rats in Retinal Ischemia/Reperfusion. Neurochemical research. vol 41. issue 5. 2016-12-13. PMID:26830289. |
it has been demonstrated that matrix metalloproteinase 3 (mmp3) is integrally involved in the neuronal degeneration of the central nervous system by promoting glial activation, neuronal apoptosis and damage to the brain-blood barrier. |
2016-12-13 |
2023-08-13 |
rat |
| Li Wang, Rui-Zhi Tan, Yue Chen, Hong-Lian Wang, Yu-Hang Liu, Dan Wen, Jun-Ming Fa. CagA promotes proliferation and secretion of extracellular matrix by inhibiting signaling pathway of apoptosis in rat glomerular mesangial cells. Renal failure. vol 38. issue 3. 2016-12-13. PMID:26837331. |
caga promotes proliferation and secretion of extracellular matrix by inhibiting signaling pathway of apoptosis in rat glomerular mesangial cells. |
2016-12-13 |
2023-08-13 |
rat |
| Li Wang, Rui-Zhi Tan, Yue Chen, Hong-Lian Wang, Yu-Hang Liu, Dan Wen, Jun-Ming Fa. CagA promotes proliferation and secretion of extracellular matrix by inhibiting signaling pathway of apoptosis in rat glomerular mesangial cells. Renal failure. vol 38. issue 3. 2016-12-13. PMID:26837331. |
we found that caga promoted cell proliferation and extracellular matrix secretion by inhibiting signaling pathway of apoptosis. |
2016-12-13 |
2023-08-13 |
rat |
| b' A Piek, R A de Boer, H H W Sillj\\xc3\\xa. The fibrosis-cell death axis in heart failure. Heart failure reviews. vol 21. issue 2. 2016-12-13. PMID:26883434.' |
whereas pathological and physiological (exercise, pregnancy) overload both stimulate cardiomyocyte growth (hypertrophy), only pathological remodeling is characterized by increased deposition of extracellular matrix proteins, termed fibrosis, and loss of cardiomyocytes by necrosis, apoptosis and/or phagocytosis. |
2016-12-13 |
2023-08-13 |
Not clear |
| Sonia Y Velásquez, Doreen Killian, Jutta Schulte, Carsten Sticht, Manfred Thiel, Holger A Lindne. Short Term Hypoxia Synergizes with Interleukin 15 Priming in Driving Glycolytic Gene Transcription and Supports Human Natural Killer Cell Activities. The Journal of biological chemistry. vol 291. issue 25. 2016-11-14. PMID:27129235. |
unexpectedly, hypoxia also stimulated migration of nk cells through the extracellular matrix and shifted amounts of susceptible leukemia target cells toward late apoptosis in a cell killing assay. |
2016-11-14 |
2023-08-13 |
human |
| Kristine Y DeLeon-Pennell, Yuan Tian, Bai Zhang, Courtney A Cates, Rugmani Padmanabhan Iyer, Presley Cannon, Punit Shah, Paul Aiyetan, Ganesh V Halade, Yonggang Ma, Elizabeth Flynn, Zhen Zhang, Yu-Fang Jin, Hui Zhang, Merry L Lindse. CD36 Is a Matrix Metalloproteinase-9 Substrate That Stimulates Neutrophil Apoptosis and Removal During Cardiac Remodeling. Circulation. Cardiovascular genetics. vol 9. issue 1. 2016-11-10. PMID:26578544. |
cd36 is a matrix metalloproteinase-9 substrate that stimulates neutrophil apoptosis and removal during cardiac remodeling. |
2016-11-10 |
2023-08-13 |
Not clear |
| Ilea T Swinehart, Stephen F Badyla. Extracellular matrix bioscaffolds in tissue remodeling and morphogenesis. Developmental dynamics : an official publication of the American Association of Anatomists. vol 245. issue 3. 2016-11-10. PMID:26699796. |
during normal morphogenesis the extracellular matrix (ecm) influences cell motility, proliferation, apoptosis, and differentiation. |
2016-11-10 |
2023-08-13 |
Not clear |
| Pawel Szul. Abdominal aortic calcification: A reappraisal of epidemiological and pathophysiological data. Bone. vol 84. 2016-11-07. PMID:26688274. |
vitamin k-dependent proteins protect vascular tunica media against formation of calcified deposits (matrix gla protein, gla-rich protein) and against vsmc apoptosis (gas6). |
2016-11-07 |
2023-08-13 |
Not clear |
| Lorell N Discenza, Georgia Cornelius, Jinping Gan, Nicolas Szapiel, Randy L Talbott, Charu Chaudhry, Anirban Roy, Robert M Borzilleri, Ragini Vuppugalla, Kevin Stefanski, Robin Moore, Celia J D'Arienzo, Timothy V Olah, John T Meh. Ultrasensitive quantitative LC-MS/MS of an inhibitor of apoptosis protein's antagonist in plasma using protein target affinity extraction. Bioanalysis. vol 8. issue 4. 2016-11-07. PMID:26807991. |
methodology & results: affinity extraction (ae) utilizing immobilized target protein bir2/bir3 was used to selectively capture the inhibitor of apoptosis proteins molecule from dog plasma and enable removal of background matrix components. |
2016-11-07 |
2023-08-13 |
dog |
| Annie Pardo, Sandra Cabrera, Mariel Maldonado, Moisés Selma. Role of matrix metalloproteinases in the pathogenesis of idiopathic pulmonary fibrosis. Respiratory research. vol 17. 2016-11-02. PMID:26944412. |
thus, these enzymes can not only degrade all the components of the extracellular matrix, but they are also able to release, cleave and activate a wide range of growth factors, cytokines, chemokines and cell surface receptors affecting numerous cell functions including adhesion, proliferation, differentiation, recruiting and transmigration, and apoptosis. |
2016-11-02 |
2023-08-13 |
mouse |
| Jun Wang, Clay Rouse, Jeff S Jasper, Ann Marie Pendergas. ABL kinases promote breast cancer osteolytic metastasis by modulating tumor-bone interactions through TAZ and STAT5 signaling. Science signaling. vol 9. issue 413. 2016-10-24. PMID:26838548. |
abl kinases protected tumor cells from apoptosis induced by trail (tnf-related apoptosis-inducing ligand), activated the transcription factor stat5, and promoted osteolysis through the stat5-dependent expression of genes encoding the osteoclast-activating factors interleukin-6 (il-6) and matrix metalloproteinase 1 (mmp1). |
2016-10-24 |
2023-08-13 |
mouse |
| Anna Lundmark, Haleh Davanian, Tove Båge, Gunnar Johannsen, Catalin Koro, Joakim Lundeberg, Tülay Yucel-Lindber. Transcriptome analysis reveals mucin 4 to be highly associated with periodontitis and identifies pleckstrin as a link to systemic diseases. Scientific reports. vol 5. 2016-10-21. PMID:26686060. |
the up-regulated genes in periodontitis were related to inflammation, wounding and defense response, and apoptosis, whereas down-regulated genes were related to extracellular matrix organization and structural support. |
2016-10-21 |
2023-08-13 |
human |
| Jiaying Zhao, Yuankun Cai, Chenqing Yin, You Lv, Wanmin Wei, Xin Wang, Zong Hao, Chenxia Shen, Huipeng Wang, Jun Che. Study on the inhibition of hyperthermic CO₂ pneumoperitoneum on the proliferation and migration of colon cancer cells and its mechanism. Oncology reports. vol 35. issue 2. 2016-10-17. PMID:26718327. |
the growth and morphology of cells were observed under a microscope, the inhibition on cell proliferation was measured using wst-8 test, cell apoptosis and the cell cycle were monitored using fluorescence-activated cell sorting analysis, the migration of cells was tested using the scratch assay, and the expression of hsp-70, caspase-3, hypoxia-inducible factor-1α (hif-1α) and matrix metalloproteinase-9 (mmp-9) proteins and genes was investigated using western blotting and reverse transcription polymerase chain reaction. |
2016-10-17 |
2023-08-13 |
Not clear |
| Robert Domitrović, Iva Potočnja. A comprehensive overview of hepatoprotective natural compounds: mechanism of action and clinical perspectives. Archives of toxicology. vol 90. issue 1. 2016-10-14. PMID:26377694. |
additionally, antifibrotic properties of phytochemicals have been closely associated with apoptosis of hepatic stellate cells and stimulation of extracellular matrix degradation. |
2016-10-14 |
2023-08-13 |
Not clear |
| Qi Hu, Jing Chen, Jing Zhang, Changwu Xu, Shuo Yang, Hong Jian. IOX1, a JMJD2A inhibitor, suppresses the proliferation and migration of vascular smooth muscle cells induced by angiotensin II by regulating the expression of cell cycle-related proteins. International journal of molecular medicine. vol 37. issue 1. 2016-10-14. PMID:26530537. |
the epigenetic modification of vascular smooth muscle cell (vsmc) phenotypic switching, proliferation, migration, apoptosis and extracellular matrix synthesis is known to occur in atherosclerosis. |
2016-10-14 |
2023-08-13 |
Not clear |
| Svetlana Farberov, Rina Meida. Thrombospondin-1 Affects Bovine Luteal Function via Transforming Growth Factor-Beta1-Dependent and Independent Actions. Biology of reproduction. vol 94. issue 1. 2016-10-14. PMID:26658711. |
their gene products can promote vascular instability, apoptosis, and matrix remodeling during luteolysis. |
2016-10-14 |
2023-08-13 |
cattle |
| Jonathan A Kirk, Oscar H Cingolan. Thrombospondins in the transition from myocardial infarction to heart failure. Journal of molecular and cellular cardiology. vol 90. 2016-10-11. PMID:26686988. |
in the present review, we provide basic as well as clinical evidence linking the thrombospondin proteins with the post myocardial infarction response, including inflammation, fibrotic matrix remodeling, angiogenesis, as well as myocyte hypertrophy, apoptosis, and contractile dysfunction in heart failure. |
2016-10-11 |
2023-08-13 |
Not clear |
| Xianyong Cao, Lin He, Yanhua L. Effects of PPARγ agonistrosiglitazone on human retinoblastoma cell in vitro and in vivo. International journal of clinical and experimental pathology. vol 8. issue 10. 2016-10-06. PMID:26722443. |
the cell biological behavior was detected, specifically, the effects of rosiglitazone on cell viability and apoptosis of the human retinoblastoma y79 cells were investigated by mtt assay and hochest 33258 staining and the migration assay showed that rosiglitazone blocked the invasion and migration of the carcinoma cells through the reconstituted extracellular matrix (matrigel). |
2016-10-06 |
2023-08-13 |
mouse |
| Bo Li, Song Su, Meng-Yu Zhang, Lei He, Qing-Da Wang, Kai H. Effect of GnT-V knockdown on the proliferation, migration and invasion of the SMMC7721/R human hepatocellular carcinoma drug-resistant cell line. Molecular medicine reports. vol 13. issue 1. 2016-09-26. PMID:26531171. |
furthermore, the possible mechanism underlying these phenomena may be associated with the induction of mitochondria‑mediated apoptosis, inhibition of the degradation of the extracellular matrix and an enhancement of the drug-sensitivity. |
2016-09-26 |
2023-08-13 |
human |