| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hanlei Zhou, Chuangang You, Xingang Wang, Ronghua Jin, Pan Wu, Qiong Li, Chunmao Ha. The progress and challenges for dermal regeneration in tissue engineering. Journal of biomedical materials research. Part A. vol 105. issue 4. 2017-11-03. PMID:28063210. |
it is a complex process involving cell migration, proliferation, differentiation, apoptosis, and the synthesis and remodeling of the extracellular matrix (ecm). |
2017-11-03 |
2023-08-13 |
Not clear |
| Agnieszka Strzelecka-Kiliszek, Saida Mebarek, Monika Roszkowska, René Buchet, David Magne, Slawomir Pikul. Functions of Rho family of small GTPases and Rho-associated coiled-coil kinases in bone cells during differentiation and mineralization. Biochimica et biophysica acta. General subjects. vol 1861. issue 5 Pt A. 2017-10-26. PMID:28188861. |
rocks have multiple functions that include regulation of cellular contraction and polarity, adhesion, motility, proliferation, apoptosis, differentiation, maturation and remodeling of the extracellular matrix (ecm). |
2017-10-26 |
2023-08-13 |
Not clear |
| Yanhai Chang, Xiao Wang, Zhengming Sun, Zhankui Jin, Ming Chen, Xiaoqing Wang, Mikko J Lammi, Xiong Gu. Inflammatory cytokine of IL-1β is involved in T-2 toxin-triggered chondrocyte injury and metabolism imbalance by the activation of Wnt/β-catenin signaling. Molecular immunology. vol 91. 2017-10-26. PMID:28963928. |
mycotoxin t-2 exerts a causative role in kashin-beck disease (kbd) suffering chondrocyte apoptosis and cartilage matrix homeostasis disruption. |
2017-10-26 |
2023-08-13 |
Not clear |
| Kamil Vural, Funda Kosova, Feyzan Özdal Kurt, İbrahim Tuğl. In vitro investigation of the effect of matrix molecules on the behavior of colon cancer cells under the effect of geldanamycin derivative. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 10. 2017-10-20. PMID:29034805. |
we applied 17-allylamino-17-demethoxygeldanamycin to colon cancer cell line (colo 205) on matrix molecules to investigate the relationship of apoptosis with terminal deoxynucleotidyl transferase dutp nick end labeling immunocytochemistry and related gene expression. |
2017-10-20 |
2023-08-13 |
Not clear |
| Amina M Medhat, Khaled Sh Azab, Mahmoud M Said, Neama M El Fatih, Nermeen M El Bakar. Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 10. 2017-10-19. PMID:29022496. |
these effects were achieved through downregulating the expression of angiogenic and lymphangiogenic regulators, including signal transducer and activator of transcription 3, vascular endothelial growth factor c, and tumor necrosis factor alpha, suppressing matrix metalloproteinase-2 and -9 activities, which play a key role in tumor invasion and metastasis, and enhancing apoptosis via inducing cleaved caspase-3 and granzyme b levels. |
2017-10-19 |
2023-08-13 |
mouse |
| René G Feichtinger, Monika Oláhová, Yoshihito Kishita, Caterina Garone, Laura S Kremer, Mikako Yagi, Takeshi Uchiumi, Alexis A Jourdain, Kyle Thompson, Aaron R D'Souza, Robert Kopajtich, Charlotte L Alston, Johannes Koch, Wolfgang Sperl, Elisa Mastantuono, Tim M Strom, Saskia B Wortmann, Thomas Meitinger, Germaine Pierre, Patrick F Chinnery, Zofia M Chrzanowska-Lightowlers, Robert N Lightowlers, Salvatore DiMauro, Sarah E Calvo, Vamsi K Mootha, Maurizio Moggio, Monica Sciacco, Giacomo P Comi, Dario Ronchi, Kei Murayama, Akira Ohtake, Pedro Rebelo-Guiomar, Masakazu Kohda, Dongchon Kang, Johannes A Mayr, Robert W Taylor, Yasushi Okazaki, Michal Minczuk, Holger Prokisc. Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies. American journal of human genetics. vol 101. issue 4. 2017-10-16. PMID:28942965. |
it is an evolutionary conserved multifunctional protein localized primarily in the mitochondrial matrix and has roles in inflammation and infection processes, mitochondrial ribosome biogenesis, and regulation of apoptosis and nuclear transcription. |
2017-10-16 |
2023-08-13 |
Not clear |
| Suresh Ranga Rao, Rajasekaran Subbarayan, Supraja Ajitkumar, Dinesh Murugan Girij. 4PBA strongly attenuates endoplasmic reticulum stress, fibrosis, and mitochondrial apoptosis markers in cyclosporine treated human gingival fibroblasts. Journal of cellular physiology. vol 233. issue 1. 2017-10-10. PMID:28158898. |
after 24 hr of incubation, mrna expression of er stress markers (grp78, chop, xbp1, and xbps) and matrix protein markers (like α-sma, vegf, tgf-β, ctgf), and mitochondrial apoptosis markers estimated and compared with housekeeping gene gapdh. |
2017-10-10 |
2023-08-13 |
human |
| Livia Manzella, Elena Tirrò, Maria Stella Pennisi, Michele Massimino, Stefania Stella, Chiara Romano, Silvia Rita Vitale, Paolo Vigner. Roles of Interferon Regulatory Factors in Chronic Myeloid Leukemia. Current cancer drug targets. vol 16. issue 7. 2017-10-04. PMID:26728039. |
bcr-abl displays constitutive tyrosine kinase activity that favors cell proliferation, inhibits apoptosis and allows cell survival even in the absence of proper adhesion to the extracellular matrix. |
2017-10-04 |
2023-08-13 |
Not clear |
| Chulwon Kim, Jong Hyun Lee, Seung Ho Baek, Jeong-Hyeon Ko, Dongwoo Nam, Kwang Seok Ah. Korean Red Ginseng Extract Enhances the Anticancer Effects of Sorafenib through Abrogation of CREB and c-Jun Activation in Renal Cell Carcinoma. Phytotherapy research : PTR. vol 31. issue 7. 2017-10-04. PMID:28544385. |
korean red ginseng extract suppressed the proliferation of two rcc cell lines; activated caspase-3; caused poly(adp-ribose) polymerase cleavage; abrogated the expression of b-cell lymphoma 2, b-cell lymphoma extra large, survivin, inhibitors of apoptosis proteins-1/2, cyclooxygenase-2, cyclin d1, matrix metallopeptidase-9, and vascular endothelial growth factor; and upregulated pro-apoptotic gene products. |
2017-10-04 |
2023-08-13 |
human |
| Brandon W Heimer, Brooke E Tam, Alissa Minkovsky, Hadley D Sike. Using nanobiotechnology to increase the prevalence of epigenotyping assays in precision medicine. Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. vol 9. issue 1. 2017-10-02. PMID:27126368. |
epigenetic silencing of genes that are important for dna repair, cell cycle control, apoptosis, and cellular interactions with the extracellular matrix has been causally linked to several subtypes of cancer. |
2017-10-02 |
2023-08-13 |
Not clear |
| Fubiao Ye, Hua Wang, Zhaomin Zheng, Peiheng He, Shilabant Sen Sribastav, Huafeng Wang, Jianru Wang, Hui Liu, Victor Y L Leun. Role of SHOX2 in the development of intervertebral disc degeneration. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 35. issue 5. 2017-09-26. PMID:26697824. |
first, we detected the expression of shox2 in different stages of human ivd degeneration; then explored the role of shox2 on nucleus pulposus (np) cells proliferation and apoptosis, finally we evaluated the effect of shox2 on the production of extracellular matrix in np cells. |
2017-09-26 |
2023-08-13 |
human |
| Liwei Guo, Duan Li, Mengting Li, Lin Li, Yanmei Huan. Variant in GALNT3 Gene Linked with Reduced Coronary Artery Disease Risk in Chinese Population. DNA and cell biology. vol 36. issue 7. 2017-09-20. PMID:28453302. |
our previous study found expression of galnt3 gene was reduced in coronary artery disease (cad) patients, and it contributed to endothelial injury by regulating apoptosis and matrix metalloproteinase (mmp) expression. |
2017-09-20 |
2023-08-13 |
Not clear |
| Hui Yin Nam, Hanumantha Rao Balaji Raghavendran, Belinda Pingguan-Murphy, Azlina A Abbas, Azhar M Merican, Tunku Kamaru. Fate of tenogenic differentiation potential of human bone marrow stromal cells by uniaxial stretching affected by stretch-activated calcium channel agonist gadolinium. PloS one. vol 12. issue 6. 2017-09-20. PMID:28654695. |
analyses include image observations of immunochemistry and immunofluorescence staining from extracellular matrix (ecm) production, and measuring related tenogenic and apoptosis gene marker expression. |
2017-09-20 |
2023-08-13 |
human |
| Besra Özmen Yelken, Tuğçe Balcı, Sunde Yılmaz Süslüer, Çağla Kayabaşı, Çığır Biray Avcı, Petek Ballar Kırmızıbayrak, Cumhur Gündü. The effect of tomatine on metastasis related matrix metalloproteinase (MMP) activities in breast cancer cell model. Gene. vol 627. 2017-09-20. PMID:28669925. |
in this study, it was aimed to evaluate the effect of tomatine on cytotoxicity, apoptosis and matrix metalloproteinase inhibition in mcf-7 cell lines. |
2017-09-20 |
2023-08-13 |
human |
| Xin Duan, Muhammad Farooq Rai, Nilsson Holguin, Matthew J Silva, Debabrata Patra, Weiming Liao, Linda J Sandel. Early changes in the knee of healer and non-healer mice following non-invasive mechanical injury. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 35. issue 3. 2017-09-18. PMID:27591401. |
histological changes in cartilage and synovium, immunofluorescence pattern of cd44, aggrecan, type-ii collagen, cartilage oligomeric matrix protein and the aggrecan neo-epitope nitege, and cell apoptosis (by tunel) were examined. |
2017-09-18 |
2023-08-13 |
mouse |
| Xin Duan, Muhammad Farooq Rai, Nilsson Holguin, Matthew J Silva, Debabrata Patra, Weiming Liao, Linda J Sandel. Early changes in the knee of healer and non-healer mice following non-invasive mechanical injury. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 35. issue 3. 2017-09-18. PMID:27591401. |
we showed that tibial compression resulted in rupture of anterior cruciate ligament, cartilage matrix loss and chondrocyte apoptosis at the injury site. |
2017-09-18 |
2023-08-13 |
mouse |
| Tengfei Song, Jun Ma, Lei Guo, Peng Yang, Xuhui Zhou, Tianwen Y. Regulation of chondrocyte functions by transient receptor potential cation channel V6 in osteoarthritis. Journal of cellular physiology. vol 232. issue 11. 2017-09-18. PMID:28063212. |
furthermore, to investigate the effects of trpv6 on chondrocyte extracellular matrix secretion, the release of matrix degrading enzymes, cell proliferation, and apoptosis, we decreased and increased trpv6 expression in chondrocytes with lentiviral constructs encoding shrna targeting trpv6 and encoding trpv6, respectively. |
2017-09-18 |
2023-08-13 |
mouse |
| Tengfei Song, Jun Ma, Lei Guo, Peng Yang, Xuhui Zhou, Tianwen Y. Regulation of chondrocyte functions by transient receptor potential cation channel V6 in osteoarthritis. Journal of cellular physiology. vol 232. issue 11. 2017-09-18. PMID:28063212. |
in addition, deficiency of trpv6 clearly affected chondrocyte function, such as extracellular matrix secretion, the release of matrix degrading enzymes, cell proliferation, and apoptosis. |
2017-09-18 |
2023-08-13 |
mouse |
| Agnieszka Owczarczyk-Saczonek, Waldemar Place. Interleukin-17 as a factor linking the pathogenesis of psoriasis with metabolic disorders. International journal of dermatology. vol 56. issue 3. 2017-09-15. PMID:27696392. |
based on the studies performed so far, it is assumed that il-17 contributes to development of atherosclerosis by means of: stimulation of production of proinflammatory compounds; induction of apoptosis of endothelial cells and heart muscle cells; stimulation of von willebrand factor production; and induction of the matrix metalloproteinase-9 (atherosclerotic plaque rupture). |
2017-09-15 |
2023-08-13 |
Not clear |
| N Godin-Heymann, S Brabetz, M M Murillo, M Saponaro, C R Santos, A Lobley, P East, P Chakravarty, N Matthews, G Kelly, S Jordan, E Castellano, J Downwar. Tumour-suppression function of KLF12 through regulation of anoikis. Oncogene. vol 35. issue 25. 2017-09-11. PMID:26455320. |
knockdown of klf12 in parental cells results in decreased apoptosis following cell detachment from matrix. |
2017-09-11 |
2023-08-13 |
Not clear |