| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhu-Qing He, Peng-Fei Huan, Li Wang, Jian-Cheng H. Paeoniflorin ameliorates cognitive impairment in Parkinson's disease via JNK/p53 signaling. Metabolic brain disease. 2022-03-01. PMID:35230626. |
additionally, pf improved 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced neuronal injury by inhibiting apoptosis in hippocampal neurons of the ca1 and ca3, and upregulating psd-95 as well as syn protein levels. |
2022-03-01 |
2023-08-13 |
mouse |
| Asli Aykac, Kerem Teralı, Dilek Özbeyli, Seren Ede, Ömercan Albayrak, Kemal Hüsnü Can Başer, Göksel Şene. A multi-parameter evaluation of the neuroprotective and cognitive-enhancing effects of Origanum onites L. (Turkish Oregano) essential oil on scopolamine-induced amnestic rats. Metabolic brain disease. 2022-02-24. PMID:35201555. |
the observed effects could be attributed to inhibition of acetylcholinesterase activity, attenuation of oxidative stress and prevention of neuronal apoptosis in the hippocampus and frontal cortex of ad rats. |
2022-02-24 |
2023-08-13 |
rat |
| Monika Herian, Adam Wojtas, Marzena Maćkowiak, Agnieszka Wawrzczak-Bargiela, Anna Solarz, Agnieszka Bysiek, Katarzyna Madej, Krystyna Gołembiowsk. Neurotoxicological profile of the hallucinogenic compound 25I-NBOMe. Scientific reports. vol 12. issue 1. 2022-02-22. PMID:35190675. |
in this article 25i-nbome-crossing through the blood-brain barrier (bbb), the impact on dna damage, apoptosis induction, and changes in the number of cortical and hippocampal cells were studied. |
2022-02-22 |
2023-08-13 |
rat |
| Statement of Retraction: Silencing of PTEN inhibits the oxidative stress damage and hippocampal cell apoptosis induced by Sevoflurane through activating MEK1/ERK signaling pathway in infant rats. Cell cycle (Georgetown, Tex.). 2022-02-22. PMID:35191822. |
statement of retraction: silencing of pten inhibits the oxidative stress damage and hippocampal cell apoptosis induced by sevoflurane through activating mek1/erk signaling pathway in infant rats. |
2022-02-22 |
2023-08-13 |
rat |
| Behzad Dehqanizadeh, Ziya Fallah Mohammadi, Abdol Hossein Taheri Kalani, Seyed Javad Mirghan. Effect of Early Exercise on Inflammatory Parameters and Apoptosis in CA1 Area of the Hippocampus Following Cerebral Ischemia-reperfusion in Rats. Brain research bulletin. 2022-02-21. PMID:35189318. |
effect of early exercise on inflammatory parameters and apoptosis in ca1 area of the hippocampus following cerebral ischemia-reperfusion in rats. |
2022-02-21 |
2023-08-13 |
rat |
| Behzad Dehqanizadeh, Ziya Fallah Mohammadi, Abdol Hossein Taheri Kalani, Seyed Javad Mirghan. Effect of Early Exercise on Inflammatory Parameters and Apoptosis in CA1 Area of the Hippocampus Following Cerebral Ischemia-reperfusion in Rats. Brain research bulletin. 2022-02-21. PMID:35189318. |
the purpose of this study was to evaluate the effect of early exercise on inflammatory parameters and apoptosis in the ca1 area of the hippocampus following cerebral i/r in adult male rats. |
2022-02-21 |
2023-08-13 |
rat |
| Yolanda Diz-Chaves, Salvador Herrera-Pérez, Lucas C González-Matías, Federico Mall. Effects of Glucagon-like peptide 1 (GLP-1) analogs in the hippocampus. Vitamins and hormones. vol 118. 2022-02-19. PMID:35180937. |
glp-1 enhances learning and memory in the hippocampus, promotes neurogenesis, decreases inflammation and apoptosis, modulates reward behavior, and reduces food intake. |
2022-02-19 |
2023-08-13 |
Not clear |
| Hui Yao, Dalin Zhang, Hao Yu, Hui Shen, Xinze Lan, Hao Liu, Xiaohuan Chen, Xu Wu, Guohua Zhang, Xiaolong Wan. AMPAkine CX516 alleviated chronic ethanol exposure-induced neurodegeneration and depressive-like behavior in mice. Toxicology and applied pharmacology. 2022-02-19. PMID:35181401. |
in addition, cx516 attenuated the levels of pro-inflammatory (il-6, il-1β), apoptosis (bax, bcl-2), and neurodegeneration (fjc) in the mouse hippocampus induced by cee. |
2022-02-19 |
2023-08-13 |
mouse |
| Rukmani Pandey, Asmita Garg, Keerti Gupta, Pallavi Shukla, Kapil Mandrah, Somendu Roy, Naibedya Chattopadhyay, Sanghamitra Bandyopadhya. Arsenic Induces Differential Neurotoxicity in Male, Female, and E2-Deficient Females: Comparative Effects on Hippocampal Neurons and Cognition in Adult Rats. Molecular neurobiology. 2022-02-17. PMID:35175559. |
supporting this, arsenic-treated male rats demonstrated larger reduction in the hippocampal neun and %-surviving neurons, together with increased apoptosis and altered bmp2/smad and bdnf/trkb pathways compared to their female counterparts. |
2022-02-17 |
2023-08-13 |
rat |
| Chengzhi Zhang, Yanmei Yang, Yanhui Gao, Dianjun Su. NaF-induced neurotoxicity via activation of the IL-1β/JNK signaling pathway. Toxicology. 2022-02-16. PMID:35172196. |
therefore, our study demonstrates that the il-1β/jnk signaling pathway is involved in naf-induced apoptosis of hippocampal neurons and cognitive dysfunction. |
2022-02-16 |
2023-08-13 |
rat |
| Seyed Mehdi Vatandoust, Gholam Hossein Meftah. The Effect of Sericin on the Cognitive Impairment, Depression, and Anxiety Caused by Learned Helplessness in Male Mice. Journal of molecular neuroscience : MN. 2022-02-15. PMID:35165850. |
at molecular levels, sericin increased the levels of synaptophysin, synapsin-1, and psd-95, and decreased apoptosis in the hippocampus. |
2022-02-15 |
2023-08-13 |
mouse |
| Dan Chen, Yi Zhang, Lian Ji, Yubin W. CREG mitigates neonatal HIE injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating AKT signaling. Cell biology international. 2022-02-10. PMID:35143104. |
creg mitigates neonatal hie injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating akt signaling. |
2022-02-10 |
2023-08-13 |
rat |
| Dan Chen, Yi Zhang, Lian Ji, Yubin W. CREG mitigates neonatal HIE injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating AKT signaling. Cell biology international. 2022-02-10. PMID:35143104. |
besides, creg overexpression promoted survival while inhibited apoptosis in ogd/r-induced hippocampal neurons accompanied by akt signaling activation, which could be reversed by creg silence. |
2022-02-10 |
2023-08-13 |
rat |
| Dan Chen, Yi Zhang, Lian Ji, Yubin W. CREG mitigates neonatal HIE injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating AKT signaling. Cell biology international. 2022-02-10. PMID:35143104. |
collectedly, we demonstrated that creg protected hippocampal neurons from hypoxic ischemia-induced injury through regulating survival and apoptosis via activating akt signaling pathway. |
2022-02-10 |
2023-08-13 |
rat |
| Chunyan Fu, Qincui Shuang, Yonghui Liu, Li Zeng, Wen S. Baihe Extracts Reduce the Activation and Apoptosis of Microglia in the Hippocampus of Mice with Depression-like Behaviors by Downregulating MYC. ACS chemical neuroscience. 2022-02-09. PMID:35139304. |
baihe extracts reduce the activation and apoptosis of microglia in the hippocampus of mice with depression-like behaviors by downregulating myc. |
2022-02-09 |
2023-08-13 |
mouse |
| Huiqing Lu, Lili Gong, Huangfang Xu, Qiongjie Zhou, Huanqiang Zhao, Suwen Wu, Rong Hu, Xiaotian L. Environmental Enrichment Protects Offspring of a Rat Model of Preeclampsia from Cognitive Decline. Cellular and molecular neurobiology. 2022-02-04. PMID:35119541. |
immunofluorescence was performed to evaluate cell proliferation and apoptosis in the dg region of the hippocampus. |
2022-02-04 |
2023-08-13 |
rat |
| Huiqing Lu, Lili Gong, Huangfang Xu, Qiongjie Zhou, Huanqiang Zhao, Suwen Wu, Rong Hu, Xiaotian L. Environmental Enrichment Protects Offspring of a Rat Model of Preeclampsia from Cognitive Decline. Cellular and molecular neurobiology. 2022-02-04. PMID:35119541. |
furthermore, cell apoptosis in the hippocampus was increased in the l-name group. |
2022-02-04 |
2023-08-13 |
rat |
| Huiqing Lu, Lili Gong, Huangfang Xu, Qiongjie Zhou, Huanqiang Zhao, Suwen Wu, Rong Hu, Xiaotian L. Environmental Enrichment Protects Offspring of a Rat Model of Preeclampsia from Cognitive Decline. Cellular and molecular neurobiology. 2022-02-04. PMID:35119541. |
ee improved the cognitive ability of offspring in the l-name group and resulted in increased hippocampal neurogenesis and synaptic protein expression levels and decreased apoptosis and inflammatory cytokine levels. |
2022-02-04 |
2023-08-13 |
rat |
| Huiqing Lu, Lili Gong, Huangfang Xu, Qiongjie Zhou, Huanqiang Zhao, Suwen Wu, Rong Hu, Xiaotian L. Environmental Enrichment Protects Offspring of a Rat Model of Preeclampsia from Cognitive Decline. Cellular and molecular neurobiology. 2022-02-04. PMID:35119541. |
environmental enrichment resolves cognitive impairment in the offspring of a rat model of preeclampsia by improving hippocampal neurogenesis and synaptic plasticity and normalizing the apoptosis level and the inflammatory balance. |
2022-02-04 |
2023-08-13 |
rat |
| Suchan Liao, Ying Luo, Jun Wu, Titikorn Chunchai, Busarin Arunsak, Juthipong Benjanuwattra, Nattayaporn Apaijai, Nipon Chattipakorn, Siriporn C Chattipakor. Apoptosis inhibitor attenuates cardiac ischemia/reperfusion injury-induced amyloid beta aggregation and dendritic spine loss in rats. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35108940. |
mechanistically, dendritic spine loss in hippocampus, due to oxidative stress/inflammation induced apoptosis, is proposed as one of responsible mechanisms underlying cognitive impairments. |
2022-02-03 |
2023-08-13 |
rat |