| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ping Zheng, Qingke Bai, Jiugeng Feng, Bing Zhao, Jian Duan, Lin Zhao, Ning Liu, Dabin Ren, Shufeng Zou, Wei Che. Neonatal microglia and proteinase inhibitors-treated adult microglia improve traumatic brain injury in rats by resolving the neuroinflammation. Bioengineering & translational medicine. vol 7. issue 1. 2022-01-26. PMID:35079627. |
the injection of neonatal microglia inhibited cell apoptosis, reduced astrocytosis and microgliosis, decreased the level of chemokines and cytokines in cortex and ipsilateral hippocampus, and improved cognitive function of tbi rat model. |
2022-01-26 |
2023-08-13 |
rat |
| Yujing Huang, Yinshi Jin, Shuai Yao, Guangxian Nan, Ying Ma. LncRNA NEAT1 Inhibits Neuronal Apoptosis and Induces Neuronal Viability of Depressed Rats Via microRNA-320-3p/CRHR1 Axis. Neurochemical research. 2022-01-25. PMID:35075548. |
cell viability and apoptosis were measured in cort-induced hippocampal neurons. |
2022-01-25 |
2023-08-13 |
rat |
| Yujing Huang, Yinshi Jin, Shuai Yao, Guangxian Nan, Ying Ma. LncRNA NEAT1 Inhibits Neuronal Apoptosis and Induces Neuronal Viability of Depressed Rats Via microRNA-320-3p/CRHR1 Axis. Neurochemical research. 2022-01-25. PMID:35075548. |
silencing neat1 or elevating mir-320-3p improved behavioral functions, attenuated pathological damage and apoptosis in the hippocampus, and increased monoamine neurotransmitter in depressed rats. |
2022-01-25 |
2023-08-13 |
rat |
| Yujing Huang, Yinshi Jin, Shuai Yao, Guangxian Nan, Ying Ma. LncRNA NEAT1 Inhibits Neuronal Apoptosis and Induces Neuronal Viability of Depressed Rats Via microRNA-320-3p/CRHR1 Axis. Neurochemical research. 2022-01-25. PMID:35075548. |
repression of neat1 or promotion of mir-320-3p enhanced viability and suppressed apoptosis of cort-treated hippocampal neurons. |
2022-01-25 |
2023-08-13 |
rat |
| Lihua Yang, Hongfei Chen, Lina Guan, Yucan X. Sevoflurane Offers Neuroprotection in a Cerebral Ischemia/Reperfusion Injury Rat Model Through the E2F1/EZH2/TIMP2 Regulatory Axis. Molecular neurobiology. 2022-01-22. PMID:35064540. |
a rat model of cerebral i/r injury was established and pre-treated with sevoflurane, in which hippocampal neuron apoptosis was found to be repressed and the level of e2f transcription factor 1 (e2f1) was observed to be down-regulated. |
2022-01-22 |
2023-08-13 |
rat |
| Lihua Yang, Hongfei Chen, Lina Guan, Yucan X. Sevoflurane Offers Neuroprotection in a Cerebral Ischemia/Reperfusion Injury Rat Model Through the E2F1/EZH2/TIMP2 Regulatory Axis. Molecular neurobiology. 2022-01-22. PMID:35064540. |
after that, it was substantiated in vivo that sevoflurane suppressed the apoptosis of hippocampal neurons in rats with cerebral i/r injury by down-regulating e2f1 to activate the ezh2/timp2 axis. |
2022-01-22 |
2023-08-13 |
rat |
| Lida Farhadi, Vida Hojati, Mehdi Khaksari, Golamhassan Vaez. Neuroprotective Effects of Crocin Against Ethanol Neurotoxicity in the Animal Model of Fetal Alcohol Spectrum Disorders. Neurochemical research. 2022-01-18. PMID:35040027. |
this study evaluated the crocin protective impact on ethanol-related neuroinflammation and neuronal apoptosis in the hippocampus of rat pups exposed to alcohol over postnatal days. |
2022-01-18 |
2023-08-13 |
rat |
| Dongze Li, Na Xu, Yanyan Hou, Wenjing Ren, Na Zhang, Xi Wang, Yeying Sun, Wenxue Lu, Guiwu Qu, Yan Yu, Changjun Lv, Fang Ha. Abnormal lipid droplets accumulation induced cognitive deficits in obstructive sleep apnea syndrome mice via JNK/SREBP/ACC pathway but not through PDP1/PDC pathway. Molecular medicine (Cambridge, Mass.). vol 28. issue 1. 2022-01-15. PMID:35030992. |
here, our study found that about 3 months cih treatment induced lipid droplets (lds) accumulation in hippocampal nerve and glia cells of c57bl/6 mice, and caused severe neuro damage including neuron lesions, neuroblast (nb) apoptosis and abnormal glial activation. |
2022-01-15 |
2023-08-13 |
mouse |
| Bagher Pourheydar, Mojgan Abar, Gholamhossein Farjah, Maryam Pourheydar, Leila Derafshpou. Curcumin alleviates restraint stress-induced learning and memory deficit and activity via modulation of biochemical, morphology changes, and apoptosis in the prefrontal cortex and hippocampus. Behavioral neuroscience. 2022-01-13. PMID:35025528. |
curcumin alleviates restraint stress-induced learning and memory deficit and activity via modulation of biochemical, morphology changes, and apoptosis in the prefrontal cortex and hippocampus. |
2022-01-13 |
2023-08-13 |
rat |
| Bagher Pourheydar, Mojgan Abar, Gholamhossein Farjah, Maryam Pourheydar, Leila Derafshpou. Curcumin alleviates restraint stress-induced learning and memory deficit and activity via modulation of biochemical, morphology changes, and apoptosis in the prefrontal cortex and hippocampus. Behavioral neuroscience. 2022-01-13. PMID:35025528. |
the present study is designed to investigate the effects of curcumin on learning and memory, activity, biochemical, morphology changes, and apoptosis in the hippocampus and prefrontal cortex of restraint stress rats. |
2022-01-13 |
2023-08-13 |
rat |
| Hui Wang, Yanbing Liu, Ziyu Guo, Kexin Wu, Yunhao Zhang, Yanan Tian, Baoyu Zhao, Hao L. Aconitine induces cell apoptosis via mitochondria and death receptor signaling pathways in hippocampus cell line. Research in veterinary science. vol 143. 2022-01-13. PMID:35026629. |
aconitine induces cell apoptosis via mitochondria and death receptor signaling pathways in hippocampus cell line. |
2022-01-13 |
2023-08-13 |
Not clear |
| Natalija Arsenijevic, Dragica Selakovic, Jelena S Katanic Stankovic, Vladimir Mihailovic, Slobodanka Mitrovic, Jovana Milenkovic, Pavle Milanovic, Miroslav Vasovic, Aleksandra Nikezic, Olivera Milosevic-Djordjevic, Marko Zivanovic, Nenad Filipovic, Vladimir Jakovljevic, Nemanja Jovicic, Gvozden Rosi. Variable neuroprotective role of Filipendula ulmaria extract in rat hippocampus. Journal of integrative neuroscience. vol 20. issue 4. 2022-01-08. PMID:34997711. |
appropriate behavioral tests were performed to assess anxiety levels, while oxidative status and apoptosis parameters were determined in the hippocampus samples. |
2022-01-08 |
2023-08-13 |
rat |
| Lihui Wang, Jinjin Cao, Qianqian Xu, Xiaomei Lu, Xin Yang, Qiong Song, Shuai Chen, Kechen Du, Renbin Huang, Chunlin Zo. 2-Dodecyl-6-Methoxycyclohexa-2,5-Diene-1,4-Dione Ameliorates Diabetic Cognitive Impairment Through Inhibiting Hif3α and Apoptosis. Frontiers in pharmacology. vol 12. 2022-01-03. PMID:34975464. |
although the etiology of diabetic cognitive impairment is complex and multifactorial, the hippocampus neuronal apoptosis is recognized as a main cause of diabetes-induced cognitive impairment. |
2022-01-03 |
2023-08-13 |
Not clear |
| Kun Yang, Xiao-Ge Song, Jing-Ru Ruan, Sheng-Chao Cai, Cai-Feng Zhu, Xiao-Feng Qin, Meng-Meng Wu, Cheng-Gong H. [Effect of moxibustion on cognitive function and proteins related with apoptosis of hippocampal neurons in rats with vascular dementia]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 41. issue 12. 2021-12-22. PMID:34936277. |
[effect of moxibustion on cognitive function and proteins related with apoptosis of hippocampal neurons in rats with vascular dementia]. |
2021-12-22 |
2023-08-13 |
rat |
| Kun Yang, Xiao-Ge Song, Jing-Ru Ruan, Sheng-Chao Cai, Cai-Feng Zhu, Xiao-Feng Qin, Meng-Meng Wu, Cheng-Gong H. [Effect of moxibustion on cognitive function and proteins related with apoptosis of hippocampal neurons in rats with vascular dementia]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 41. issue 12. 2021-12-22. PMID:34936277. |
to observe the effect of moxibustion on proteins related with apoptosis of hippocampal neurons in rats with vascular dementia (vd), and to explore the possible mechanism of moxibustion on improving vd. |
2021-12-22 |
2023-08-13 |
rat |
| Xiao-Tong Zhang, Yuan Zhang, Yuan-Xiang Zhang, Zhen-Yi Jiang, Hui Yang, Lan Jiang, Bin Yang, Jiu-Cui Ton. Helicid Reverses the Effect of Overexpressing Journal of healthcare engineering. vol 2021. 2021-12-21. PMID:34931140. |
helicid reverses the effect of overexpressing increasing evidence has shown that apoptosis in the hippocampus is closely related to depressive-like behavior. |
2021-12-21 |
2023-08-13 |
Not clear |
| Ghasem Majdi Yazdi, Gholamhasan Vaezi, Vida Hojati, Mohammad Mohammad-Zade. The Effect of 6-gingerol on Growth Factors and Apoptosis Indices in Rats Exposed to Gold Nanoparticles. Basic and clinical neuroscience. vol 12. issue 3. 2021-12-17. PMID:34917289. |
given the antioxidant properties of gingerol (ging), this study aimed to determine the protective effect of 6-gingerol on hippocampal levels of brain-derived neurotrophic factor (bdnf), nerve growth factor (ngf), dna oxidative damage, and the amount of bax and bcl2 apoptosis indices of rats exposed to aunps. |
2021-12-17 |
2023-08-13 |
rat |
| Fengming Shen, Juan Wang, Feng Gao, Jingji Wang, Guoqi Zh. Ginsenoside Rg1 Prevents Cognitive Impairment and Hippocampal Neuronal Apoptosis in Experimental Vascular Dementia Mice by Promoting GPR30 Expression. Neural plasticity. vol 2021. 2021-12-13. PMID:34899899. |
ginsenoside rg1 prevents cognitive impairment and hippocampal neuronal apoptosis in experimental vascular dementia mice by promoting gpr30 expression. |
2021-12-13 |
2023-08-13 |
mouse |
| Fengming Shen, Juan Wang, Feng Gao, Jingji Wang, Guoqi Zh. Ginsenoside Rg1 Prevents Cognitive Impairment and Hippocampal Neuronal Apoptosis in Experimental Vascular Dementia Mice by Promoting GPR30 Expression. Neural plasticity. vol 2021. 2021-12-13. PMID:34899899. |
this study is aimed at investigating the potential roles of g protein-coupled estrogen receptor 1 (gper, also known as gpr30) in the preventive effect of ginsenoside rg1 against cognitive impairment and hippocampal cell apoptosis in experimental vascular dementia (vd) in mice. |
2021-12-13 |
2023-08-13 |
mouse |
| Malk Eun Pak, You-Chang Oh, Yeo Jin Park, Jae Kwang Kim, Min-Gyeong Shin, Jong Hyuk Yoon, Younghoon G. Banhasasim-Tang Ameliorates Spatial Memory by Suppressing Oxidative Stress through Regulation of ERK/p38 Signaling in Hippocampus of Mice. Oxidative medicine and cellular longevity. vol 2021. 2021-12-13. PMID:34900088. |
in hippocampal cells, bhs treatment rescued glutamate-induced cytotoxicity, apoptosis, and oxidative stress. |
2021-12-13 |
2023-08-13 |
mouse |