| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Behzad Dehqanizadeh, Ziya Fallah Mohammadi, Abdol Hossein Taheri Kalani, Seyed Javad Mirghan. Effect of Early Exercise on Inflammatory Parameters and Apoptosis in CA1 Area of the Hippocampus Following Cerebral Ischemia-reperfusion in Rats. Brain research bulletin. 2022-02-21. PMID:35189318. |
the purpose of this study was to evaluate the effect of early exercise on inflammatory parameters and apoptosis in the ca1 area of the hippocampus following cerebral i/r in adult male rats. |
2022-02-21 |
2023-08-13 |
rat |
| Yolanda Diz-Chaves, Salvador Herrera-Pérez, Lucas C González-Matías, Federico Mall. Effects of Glucagon-like peptide 1 (GLP-1) analogs in the hippocampus. Vitamins and hormones. vol 118. 2022-02-19. PMID:35180937. |
glp-1 enhances learning and memory in the hippocampus, promotes neurogenesis, decreases inflammation and apoptosis, modulates reward behavior, and reduces food intake. |
2022-02-19 |
2023-08-13 |
Not clear |
| Hui Yao, Dalin Zhang, Hao Yu, Hui Shen, Xinze Lan, Hao Liu, Xiaohuan Chen, Xu Wu, Guohua Zhang, Xiaolong Wan. AMPAkine CX516 alleviated chronic ethanol exposure-induced neurodegeneration and depressive-like behavior in mice. Toxicology and applied pharmacology. 2022-02-19. PMID:35181401. |
in addition, cx516 attenuated the levels of pro-inflammatory (il-6, il-1β), apoptosis (bax, bcl-2), and neurodegeneration (fjc) in the mouse hippocampus induced by cee. |
2022-02-19 |
2023-08-13 |
mouse |
| Rukmani Pandey, Asmita Garg, Keerti Gupta, Pallavi Shukla, Kapil Mandrah, Somendu Roy, Naibedya Chattopadhyay, Sanghamitra Bandyopadhya. Arsenic Induces Differential Neurotoxicity in Male, Female, and E2-Deficient Females: Comparative Effects on Hippocampal Neurons and Cognition in Adult Rats. Molecular neurobiology. 2022-02-17. PMID:35175559. |
supporting this, arsenic-treated male rats demonstrated larger reduction in the hippocampal neun and %-surviving neurons, together with increased apoptosis and altered bmp2/smad and bdnf/trkb pathways compared to their female counterparts. |
2022-02-17 |
2023-08-13 |
rat |
| Chengzhi Zhang, Yanmei Yang, Yanhui Gao, Dianjun Su. NaF-induced neurotoxicity via activation of the IL-1β/JNK signaling pathway. Toxicology. 2022-02-16. PMID:35172196. |
therefore, our study demonstrates that the il-1β/jnk signaling pathway is involved in naf-induced apoptosis of hippocampal neurons and cognitive dysfunction. |
2022-02-16 |
2023-08-13 |
rat |
| Seyed Mehdi Vatandoust, Gholam Hossein Meftah. The Effect of Sericin on the Cognitive Impairment, Depression, and Anxiety Caused by Learned Helplessness in Male Mice. Journal of molecular neuroscience : MN. 2022-02-15. PMID:35165850. |
at molecular levels, sericin increased the levels of synaptophysin, synapsin-1, and psd-95, and decreased apoptosis in the hippocampus. |
2022-02-15 |
2023-08-13 |
mouse |
| Dan Chen, Yi Zhang, Lian Ji, Yubin W. CREG mitigates neonatal HIE injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating AKT signaling. Cell biology international. 2022-02-10. PMID:35143104. |
creg mitigates neonatal hie injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating akt signaling. |
2022-02-10 |
2023-08-13 |
rat |
| Dan Chen, Yi Zhang, Lian Ji, Yubin W. CREG mitigates neonatal HIE injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating AKT signaling. Cell biology international. 2022-02-10. PMID:35143104. |
besides, creg overexpression promoted survival while inhibited apoptosis in ogd/r-induced hippocampal neurons accompanied by akt signaling activation, which could be reversed by creg silence. |
2022-02-10 |
2023-08-13 |
rat |
| Dan Chen, Yi Zhang, Lian Ji, Yubin W. CREG mitigates neonatal HIE injury through survival promotion and apoptosis inhibition in hippocampal neurons via activating AKT signaling. Cell biology international. 2022-02-10. PMID:35143104. |
collectedly, we demonstrated that creg protected hippocampal neurons from hypoxic ischemia-induced injury through regulating survival and apoptosis via activating akt signaling pathway. |
2022-02-10 |
2023-08-13 |
rat |
| Chunyan Fu, Qincui Shuang, Yonghui Liu, Li Zeng, Wen S. Baihe Extracts Reduce the Activation and Apoptosis of Microglia in the Hippocampus of Mice with Depression-like Behaviors by Downregulating MYC. ACS chemical neuroscience. 2022-02-09. PMID:35139304. |
baihe extracts reduce the activation and apoptosis of microglia in the hippocampus of mice with depression-like behaviors by downregulating myc. |
2022-02-09 |
2023-08-13 |
mouse |
| Huiqing Lu, Lili Gong, Huangfang Xu, Qiongjie Zhou, Huanqiang Zhao, Suwen Wu, Rong Hu, Xiaotian L. Environmental Enrichment Protects Offspring of a Rat Model of Preeclampsia from Cognitive Decline. Cellular and molecular neurobiology. 2022-02-04. PMID:35119541. |
immunofluorescence was performed to evaluate cell proliferation and apoptosis in the dg region of the hippocampus. |
2022-02-04 |
2023-08-13 |
rat |
| Huiqing Lu, Lili Gong, Huangfang Xu, Qiongjie Zhou, Huanqiang Zhao, Suwen Wu, Rong Hu, Xiaotian L. Environmental Enrichment Protects Offspring of a Rat Model of Preeclampsia from Cognitive Decline. Cellular and molecular neurobiology. 2022-02-04. PMID:35119541. |
furthermore, cell apoptosis in the hippocampus was increased in the l-name group. |
2022-02-04 |
2023-08-13 |
rat |
| Huiqing Lu, Lili Gong, Huangfang Xu, Qiongjie Zhou, Huanqiang Zhao, Suwen Wu, Rong Hu, Xiaotian L. Environmental Enrichment Protects Offspring of a Rat Model of Preeclampsia from Cognitive Decline. Cellular and molecular neurobiology. 2022-02-04. PMID:35119541. |
ee improved the cognitive ability of offspring in the l-name group and resulted in increased hippocampal neurogenesis and synaptic protein expression levels and decreased apoptosis and inflammatory cytokine levels. |
2022-02-04 |
2023-08-13 |
rat |
| Huiqing Lu, Lili Gong, Huangfang Xu, Qiongjie Zhou, Huanqiang Zhao, Suwen Wu, Rong Hu, Xiaotian L. Environmental Enrichment Protects Offspring of a Rat Model of Preeclampsia from Cognitive Decline. Cellular and molecular neurobiology. 2022-02-04. PMID:35119541. |
environmental enrichment resolves cognitive impairment in the offspring of a rat model of preeclampsia by improving hippocampal neurogenesis and synaptic plasticity and normalizing the apoptosis level and the inflammatory balance. |
2022-02-04 |
2023-08-13 |
rat |
| Suchan Liao, Ying Luo, Jun Wu, Titikorn Chunchai, Busarin Arunsak, Juthipong Benjanuwattra, Nattayaporn Apaijai, Nipon Chattipakorn, Siriporn C Chattipakor. Apoptosis inhibitor attenuates cardiac ischemia/reperfusion injury-induced amyloid beta aggregation and dendritic spine loss in rats. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35108940. |
mechanistically, dendritic spine loss in hippocampus, due to oxidative stress/inflammation induced apoptosis, is proposed as one of responsible mechanisms underlying cognitive impairments. |
2022-02-03 |
2023-08-13 |
rat |
| Titikorn Chunchai, Nattayaporn Apaijai, Juthipong Benjanuwattra, Aysha Petel, Busarin Arunsak, Wichwara Nawara, Thidarat Jaiwongkam, Sasiwan Kerdphoo, Wasana Pratchayasakul, Nipon Chattipakorn, Siriporn C Chattipakor. Erythropoietin exerted neuroprotection against cardiac ischemic/reperfusion injury by ameliorating oxidative stress, mitochondrial dysfunction, microglial activation, apoptosis and necroptosis. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109054. |
acute cardiac ischemic/reperfusion (i/r) injury not only caused cardiac dysfunction, but also caused the development of brain dysfunction and pathology, including blood brain barrier breakdown, increased brain oxidative stress, brain mitochondrial dysfunction, brain mitochondrial dynamic imbalance, hippocampal dysplasticity, and hippocampal apoptosis. |
2022-02-03 |
2023-08-13 |
Not clear |
| Xiaoqian Peng, Li Chen, Zijuan Wang, Yingying He, John Bosco Ruganzu, Hongsong Guo, Xiao Zhang, Shengfeng Ji, Liming Zheng, Weina Yan. Tanshinone IIA regulates glycogen synthase kinase-3β-related signaling pathway and ameliorates memory impairment in APP/PS1 transgenic mice. European journal of pharmacology. 2022-01-29. PMID:35090935. |
additionally, tan iia markedly attenuated tau hyperphosphorylation and prevented neuronal loss and apoptosis in the parietal cortex and hippocampus. |
2022-01-29 |
2023-08-13 |
mouse |
| Zhongcheng Wang, Yaxin Su, Lei Zhang, Ting Lan, Li Li, Suhua Q. GSK-126 Protects CA1 Neurons from H3K27me3-Mediated Apoptosis in Cerebral Ischemia. Molecular neurobiology. 2022-01-29. PMID:35091962. |
the administration of gsk-126 to rat brains decreased the levels of h3k27me3 in the hippocampus and reduced neuronal apoptosis after experimental stroke. |
2022-01-29 |
2023-08-13 |
rat |
| Gangli Yan, Zhiwei Tao, Xiaobing Xing, Ziying Zhou, Xinghua Wang, Xing Li, Fengguang L. Down-Regulated microRNA-192-5p Protects Against Hypoxic-Ischemic Brain Damage via Regulation of YAP1-Mediated Hippo Signaling Pathway. Neurochemical research. 2022-01-27. PMID:35084661. |
the viability, apoptosis and vegf expression of hippocampal neurons in each group were also examined. |
2022-01-27 |
2023-08-13 |
rat |
| Gangli Yan, Zhiwei Tao, Xiaobing Xing, Ziying Zhou, Xinghua Wang, Xing Li, Fengguang L. Down-Regulated microRNA-192-5p Protects Against Hypoxic-Ischemic Brain Damage via Regulation of YAP1-Mediated Hippo Signaling Pathway. Neurochemical research. 2022-01-27. PMID:35084661. |
reduced mir-192-5p or augmented yap1 decelerated the neuron apoptosis, decreased the p-taz level and vegf level and promoted cell viability of ogd hippocampal neurons in vitro. |
2022-01-27 |
2023-08-13 |
rat |