| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Afsaneh Asgari Taei, Leila Dargahi, Pariya Khodabakhsh, Mehdi Kadivar, Maryam Farahmandfa. Hippocampal neuroprotection mediated by secretome of human mesenchymal stem cells against experimental stroke. CNS neuroscience & therapeutics. 2022-06-18. PMID:35715988. |
here, we explored the effects of secretome or conditioned medium (cm) derived from human embryonic stem cell-derived mscs (hesc-mscs) on hippocampal neurogenesis, inflammation, and apoptosis in experimental stroke. |
2022-06-18 |
2023-08-14 |
human |
| Hakan Sahin, Oguz Yucel, Serkan Emik, Gozde Erkanli Sentur. Protective Effects of Intranasally Administrated Oxytocin-Loaded Nanoparticles on Pentylenetetrazole-Kindling Epilepsy in Terms of Seizure Severity, Memory, Neurogenesis, and Neuronal Damage. ACS chemical neuroscience. 2022-06-17. PMID:35713692. |
hippocampus histopathology, neurogenesis, and apoptosis were demonstrated. |
2022-06-17 |
2023-08-14 |
human |
| Hakan Sahin, Oguz Yucel, Serkan Emik, Gozde Erkanli Sentur. Protective Effects of Intranasally Administrated Oxytocin-Loaded Nanoparticles on Pentylenetetrazole-Kindling Epilepsy in Terms of Seizure Severity, Memory, Neurogenesis, and Neuronal Damage. ACS chemical neuroscience. 2022-06-17. PMID:35713692. |
a significant increase of neurogenesis and decrease of apoptosis in the hippocampus of the ptz + np-ot group were observed, while ots and np-ots had protective effects against ptz-induced damage to hippocampal neurons. |
2022-06-17 |
2023-08-14 |
human |
| Hakan Sahin, Oguz Yucel, Serkan Emik, Gozde Erkanli Sentur. Protective Effects of Intranasally Administrated Oxytocin-Loaded Nanoparticles on Pentylenetetrazole-Kindling Epilepsy in Terms of Seizure Severity, Memory, Neurogenesis, and Neuronal Damage. ACS chemical neuroscience. 2022-06-17. PMID:35713692. |
our results indicate that the chronic administration of np-ots may have positive effects on hippocampal damage via increasing neurogenesis and decreasing apoptosis and seizure severity. |
2022-06-17 |
2023-08-14 |
human |
| Xiaoli Liu, Zhenfang Wang, Xi Zhang, Dingxiang Zhang, Qinghua Yang, Pengjuan Hu, Feng L. LncRNA MEG3 activates CDH2 expression by recruitment of EP300 in valproic acid-induced autism spectrum disorder. Neuroscience letters. 2022-06-13. PMID:35697159. |
the aim of the present study is to investigate the effects of lncrna maternally expressed gene 3 (meg3) on viability and apoptosis of hippocampal neurons from asd rats. |
2022-06-13 |
2023-08-14 |
mouse |
| Xiaoli Liu, Zhenfang Wang, Xi Zhang, Dingxiang Zhang, Qinghua Yang, Pengjuan Hu, Feng L. LncRNA MEG3 activates CDH2 expression by recruitment of EP300 in valproic acid-induced autism spectrum disorder. Neuroscience letters. 2022-06-13. PMID:35697159. |
after upregulation of cdh2 in neurons with sh-meg3, we found diminished viability and increased apoptosis in hippocampal neurons of asd rats. |
2022-06-13 |
2023-08-14 |
mouse |
| Chunxia Huang, John Man Tak Chu, Yan Liu, Vivian Suk Wai Kwong, Raymond Chuen Chung Chang, Gordon Tin Chun Won. Sevoflurane Induces Neurotoxicity in the Animal Model with Alzheimer's Disease Neuropathology via Modulating Glutamate Transporter and Neuronal Apoptosis. International journal of molecular sciences. vol 23. issue 11. 2022-06-10. PMID:35682930. |
our findings indicate that sevoflurane-induced cognitive deterioration in 3 × tg mice, which was accompanied with the modulation of glutamate transporter, mapk signaling, and neuronal apoptosis in the cortical and hippocampal regions. |
2022-06-10 |
2023-08-14 |
mouse |
| Amany Mohamed Shalaby, Heba E M Sharaf Eldin, Ahmed Ahmed Abdelsameea, Hanim Magdy Abdelnour, Mohamed Ali Alabiad, Mahmoud Ramadan Elkholy, Adel Mohamed Aboregel. Betahistine Attenuates Seizures, Neurodegeneration, Apoptosis, and Gliosis in the Cerebral Cortex and Hippocampus in a Mouse Model of Epilepsy: A Histological, Immunohistochemical, and Biochemical Study. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 2022-06-10. PMID:35686434. |
betahistine attenuates seizures, neurodegeneration, apoptosis, and gliosis in the cerebral cortex and hippocampus in a mouse model of epilepsy: a histological, immunohistochemical, and biochemical study. |
2022-06-10 |
2023-08-14 |
mouse |
| Malwina Lisek, Joanna Mackiewicz, Marta Sobolczyk, Bozena Ferenc, Feng Guo, Ludmila Zylinska, Tomasz Bocze. Early Developmental PMCA2b Expression Protects From Ketamine-Induced Apoptosis and GABA Impairments in Differentiating Hippocampal Progenitor Cells. Frontiers in cellular neuroscience. vol 16. 2022-06-09. PMID:35677757. |
early developmental pmca2b expression protects from ketamine-induced apoptosis and gaba impairments in differentiating hippocampal progenitor cells. |
2022-06-09 |
2023-08-14 |
Not clear |
| Yuxiang Jia, Yu Yao, Limin Zhuo, Xingxing Chen, Cuina Yan, Yonghua Ji, Jie Tao, Yudan Zh. Aerobic Physical Exercise as a Non-medical Intervention for Brain Dysfunction: State of the Art and Beyond. Frontiers in neurology. vol 13. 2022-06-01. PMID:35645958. |
we concluded that aerobic physical exercise helps to maintain the regulatory mechanisms of brain homeostasis through anti-inflammatory mechanisms and enhanced synaptic plasticity and inhibition of hippocampal atrophy and neuronal apoptosis. |
2022-06-01 |
2023-08-13 |
Not clear |
| Qin Zhou, Qiong Wang, Baomei He, Haibo Kong, Huanjun Luo, Xiaowei Wang, Wenlan Wan. MicroRNA 322-5p reduced neuronal inflammation via the TLR4/TRAF6/NF-κB axis in a rat epilepsy model. Open medicine (Warsaw, Poland). vol 17. issue 1. 2022-06-01. PMID:35647304. |
tunel detects hippocampal neuron apoptosis. |
2022-06-01 |
2023-08-13 |
rat |
| Qin Zhou, Qiong Wang, Baomei He, Haibo Kong, Huanjun Luo, Xiaowei Wang, Wenlan Wan. MicroRNA 322-5p reduced neuronal inflammation via the TLR4/TRAF6/NF-κB axis in a rat epilepsy model. Open medicine (Warsaw, Poland). vol 17. issue 1. 2022-06-01. PMID:35647304. |
exogenous mir-322-5p reduced the expression of inflammatory molecules and increased the gaba levels in se rats, and also reduced hippocampal neuronal cell apoptosis caused by epilepsy. |
2022-06-01 |
2023-08-13 |
rat |
| Jinghui Zhang, Nana Qiao, Jiwen Wang, Baomin L. Nuclear translocation of GluA2/ GAPDH promotes neurotoxicity after pilocarpine-induced epilepsy. Epilepsy research. vol 183. 2022-05-31. PMID:35636277. |
in this study, induced status epilepticus (se) in rats by the systemic administration of pilocarpine, collected hippocampal tissues at different time points after se, and assessed the relationship between glua2/gapdh coupling and neuronal apoptosis in se rats. |
2022-05-31 |
2023-08-13 |
rat |
| Jinghui Zhang, Nana Qiao, Jiwen Wang, Baomin L. Nuclear translocation of GluA2/ GAPDH promotes neurotoxicity after pilocarpine-induced epilepsy. Epilepsy research. vol 183. 2022-05-31. PMID:35636277. |
we found that the apoptosis of hippocampal neurons was most significant at 72 h after se, which was also the peak time of glua2/gapdh coupling expression and glua2 consumption. |
2022-05-31 |
2023-08-13 |
rat |
| Jinghui Zhang, Nana Qiao, Jiwen Wang, Baomin L. Nuclear translocation of GluA2/ GAPDH promotes neurotoxicity after pilocarpine-induced epilepsy. Epilepsy research. vol 183. 2022-05-31. PMID:35636277. |
after interruption of glua2/gapdh coupling, the apoptosis and memorial function of hippocampal neurons were improved and nuclear translocation of glua2/gapdh coupling was reduced. |
2022-05-31 |
2023-08-13 |
rat |
| Tae-Woon Kim, Sang-Seo Park, Hye-Sang Par. Effects of Exercise Training during Advanced Maternal Age on the Cognitive Function of Offspring. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628329. |
this study aimed to elucidate the effects of exercise training among old female animals on the cognitive function, hippocampal neuroplasticity, mitochondrial function, and apoptosis in the offspring. |
2022-05-28 |
2023-08-13 |
Not clear |
| Shan Jiang, Yong-Qiang Wang, Yi-Fei Tang, Xi Lu, Dan Gu. Pre-Exposure to Environmental Enrichment Protects against Learning and Memory Deficits Caused by Infrasound Exposure. Oxidative medicine and cellular longevity. vol 2022. 2022-05-27. PMID:35620581. |
changes to neuroinflammation, apoptosis, and oxidative stress in the hippocampus were also detected. |
2022-05-27 |
2023-08-13 |
rat |
| Xiao-Ye Lu, Hao-Long He, Qian-Yi Lü, Qi-Long Li, Ming Xu, Hao-Mei Tian, Hong Zhan. [Acupuncture mediated miR-34c-5p regulates the autophagy of hippocampal neurons in rats with cerebral ischemia/reperfusion injury]. Zhen ci yan jiu = Acupuncture research. vol 47. issue 5. 2022-05-26. PMID:35616415. |
to observe the effect of acupuncture on the expression of mir-34c-5p, autophagy-related proteins and apoptosis rate in hippocampus of rats with cerebral ischemia/reperfusion injury (ci/ri), so as to explore its mechanism in regulating autophagy in hippocampal neurons in ci/ri rats. |
2022-05-26 |
2023-08-13 |
rat |
| Carlos Henrique Rocha Catalão, Anderson de Oliveira Souza, Nilton Nascimento Santos-Junior, Luis Henrique Angenendt da Costa, Jonathas Rodrigo Dos Santos, Luciane Carla Alberici, Maria José Alves Roch. Pre-treatment and continuous administration of simvastatin during sepsis improve metabolic parameters and prevent CNS injuries in survivor rats. Molecular and cellular biochemistry. 2022-05-23. PMID:35604517. |
the clp-rats treated with simvastatin showed a reduction in plasma cytokines and improvement in metabolic parameters and locomotor activity, followed by minor alterations compatible with apoptosis and astrogliosis in the hippocampus and prefrontal cortex. |
2022-05-23 |
2023-08-13 |
rat |
| Wei Zhang, Yuewang Yang, Zifei Xiang, Jinping Cheng, Zhijun Yu, Wen Wang, Ling Hu, Fuyun Ma, Youping Deng, Zhigang Jin, Xiamin H. MRTF-A-mediated protection against amyloid-β-induced neuronal injury correlates with restoring autophagy via miR-1273g-3p/mTOR axis in Alzheimer models. Aging. vol 14. issue undefined. 2022-05-23. PMID:35604830. |
myocardia-related transcription factors-a (mrtf-a), which is enriched in the hippocampus and cerebral cortex, has been shown to have a protective function against ischemia hypoxia-induced neuronal apoptosis. |
2022-05-23 |
2023-08-13 |
mouse |