| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jianan Li, Haoran B. Integrated Strategy of Network Pharmacology and in vitro Screening to Identify Mechanism of Diazinon-induced Hippocampal Neurotoxicity. Neurotoxicology. 2022-08-07. PMID:35934178. |
dzn-induced hippocampal neurotoxicity was associated with the altered activity of multiple signaling pathways (including pi3k-akt, tnf, and apoptosis signaling). |
2022-08-07 |
2023-08-14 |
mouse |
| Haogang Sun, Xinxin Li, Qi Guo, Songyan Li. Research progress on oxidative stress regulating different types of neuronal death caused by epileptic seizures. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2022-08-04. PMID:35927358. |
the histological characteristics of hippocampal structure determine its high sensitivity to excitotoxicity and present different types of neuronal death, including apoptosis, necroptosis, autophagy, pyroptosis, and ferroptosis. |
2022-08-04 |
2023-08-14 |
Not clear |
| Z Junde, L Tingting, Z Lu, C Shan, Y Da. Lithium chloride promotes neural functional recovery after local cerebral ischemia injury in rats through Wnt signaling pathway activation. Folia morphologica. 2022-08-02. PMID:35916382. |
apoptosis of the hippocampal neurons was tested by western blot. |
2022-08-02 |
2023-08-14 |
human |
| Mengxi Lu, Xia He, Zhexiao Jiao, Zewen Hu, Zijing Guo, Shiyun Dai, Hui Wang, Dan X. The upregulation of glutamate decarboxylase 67 against hippocampal excitability damage in male fetal rats by prenatal caffeine exposure. Environmental toxicology. 2022-08-02. PMID:35917217. |
compared with the control group, hippocampal neurons of male fetal rats by pce displayed increased apoptosis and reduced synaptic plasticity, whereas glutamate decarboxylase 67 (gad67) expression was increased. |
2022-08-02 |
2023-08-14 |
rat |
| Gulin Ozdamar Unal, Arif Demirdas, Mustafa Nazıroglu, Ishak Suat Ove. Agomelatine attenuates calcium signaling and apoptosis via the inhibition of TRPV1 channel in the hippocampal neurons of rats with chronic mild stress depression model. Behavioural brain research. 2022-08-01. PMID:35914635. |
agomelatine attenuates calcium signaling and apoptosis via the inhibition of trpv1 channel in the hippocampal neurons of rats with chronic mild stress depression model. |
2022-08-01 |
2023-08-14 |
rat |
| Fernanda B Lorena, Juliana M Sato, Beatriz Martin Coviello, Alexandre J T Arnold, Alice Batistuzzo, Laís M Yamanouchi, Eduardo Dias Junior, Bruna P P do Nascimento, Tatiana de L Fonseca, Antonio C Bianco, Miriam O Ribeir. Age Worsens the Cognitive Phenotype in Mice Carrying the Thr92Ala-DIO2 Polymorphism. Metabolites. vol 12. issue 7. 2022-07-27. PMID:35888752. |
nonetheless, in both male and female pfc, there was an enrichment in genes associated with th-dependent processes, er stress, and golgi apparatus, while in the hippocampus there was additional enrichment in genes associated with inflammation and apoptosis. |
2022-07-27 |
2023-08-14 |
mouse |
| Fernanda B Lorena, Juliana M Sato, Beatriz Martin Coviello, Alexandre J T Arnold, Alice Batistuzzo, Laís M Yamanouchi, Eduardo Dias Junior, Bruna P P do Nascimento, Tatiana de L Fonseca, Antonio C Bianco, Miriam O Ribeir. Age Worsens the Cognitive Phenotype in Mice Carrying the Thr92Ala-DIO2 Polymorphism. Metabolites. vol 12. issue 7. 2022-07-27. PMID:35888752. |
in addition to reduced th signaling, er-stress, and involvement of the golgi apparatus, hippocampal inflammation and apoptosis were identified as potentially important mechanisms of a disease. |
2022-07-27 |
2023-08-14 |
mouse |
| Yuru Du, Yun Shi, Xi Wang, Han Song, Xinhao Wang, Ying Hao, Ye Zhao, Xiangfei Guo, Mengxu Shi, Miao Gong, Li Song, Sheng Wang, Yuan Gao, Haishui Sh. Hippocampal Semaphorin 3B Improves Depression-like Behaviours in Mice by Upregulating Synaptic Plasticity and Inhibiting Neuronal Apoptosis. Journal of neurochemistry. 2022-07-27. PMID:35892177. |
hippocampal semaphorin 3b improves depression-like behaviours in mice by upregulating synaptic plasticity and inhibiting neuronal apoptosis. |
2022-07-27 |
2023-08-14 |
mouse |
| Mohammad Rumman, Shivani Pandey, Babita Singh, Mrinal Gupta, Abbas Ali Mahd. Genistein suppresses microglial activation and inhibits apoptosis in different brain regions of hypoxia-exposed mice model of amnesia. Metabolic brain disease. 2022-07-27. PMID:35895244. |
moreover, hypoxia-exposed mice showed increased expression of microglial activation markers and enhanced apoptosis in the hippocampus, amygdala, and pfc. |
2022-07-27 |
2023-08-14 |
mouse |
| Titikorn Chunchai, Apiwan Arinno, Benjamin Ongnok, Patcharapong Pantiya, Thawatchai Khuanjing, Nanthip Prathumsap, Chayodom Maneechote, Nipon Chattipakorn, Siriporn C Chattipakor. Ranolazine alleviated cardiac/brain dysfunction in doxorubicin-treated rats. Experimental and molecular pathology. 2022-07-26. PMID:35882281. |
dox also caused brain pathologies as indicated by increased brain inflammation, impaired blood-brain barrier integrity, brain mitochondrial dysfunction, microglial dysmorphology, hippocampal dysplasticity, and increased apoptosis, resulting in cognitive decline. |
2022-07-26 |
2023-08-14 |
rat |
| Gaofeng Wu, Jiaqi Zhou, Maohong Yang, Chang Xu, Huiping Pang, Xia Qin, Shumei Lin, Jiancheng Yang, Jianmin H. The Regulatory Effects of Taurine on Neurogenesis and Apoptosis of Neural Stem Cells in the Hippocampus of Rats. Advances in experimental medicine and biology. vol 1370. 2022-07-26. PMID:35882810. |
the regulatory effects of taurine on neurogenesis and apoptosis of neural stem cells in the hippocampus of rats. |
2022-07-26 |
2023-08-14 |
rat |
| Fatemeh Navaei, Fatemeh Fadaei Fathabadi, Meysam Hassani Moghaddam, Mobina Fathi, Kimia Vakili, Mohammad-Amin Abdollahifar, Mahdi Eskandarian Boroujeni, Naghmeh Zamani, Nasim Zamani, Mohsen Norouzian, Abbas Aliaghae. Chronic exposure to methadone impairs memory, induces microgliosis, astrogliosis and neuroinflammation in the hippocampus of adult male rats. Journal of chemical neuroanatomy. 2022-07-25. PMID:35872237. |
according to the findings, methadone administration exerts a neurodegenerative effect on the hippocampus via dysregulation of microgliosis, astrogliosis, apoptosis, and neuro-inflammation. |
2022-07-25 |
2023-08-14 |
rat |
| Amir-Hossein Bayat, Helia Azimi, Meysam Hassani Moghaddam, Vahid Ebrahimi, Mobina Fathi, Kimia Vakili, Gholam-Reza Mahmoudiasl, Mahdi Forouzesh, Mahdi Eskandarian Boroujeni, Zahra Nariman, Hojjat-Allah Abbaszadeh, Arefeh Aryan, Abbas Aliaghaei, Mohammad-Amin Abdollahifa. COVID-19 causes neuronal degeneration and reduces neurogenesis in human hippocampus. Apoptosis : an international journal on programmed cell death. 2022-07-25. PMID:35876935. |
the results showed that in hippocampus of the studied brains there were morphological changes in pyramidal cells, an increase in apoptosis, a drop in neurogenesis, and change in spatial distribution of neurons in the pyramidal and granular layer. |
2022-07-25 |
2023-08-14 |
human |
| Zuo-Long Liu, Miao Bian, Li Pan. LncRNA CRNDE Deteriorates Delayed Encephalopathy After Acute Carbon Monoxide Poisoning to Inactivate AKT/GSK3β/β-catenin Pathway via miR-212-5p. Neurotoxicity research. 2022-07-19. PMID:35852716. |
crnde knockdown repressed the histopathological damage and apoptosis of brain and hippocampus tissues. |
2022-07-19 |
2023-08-14 |
rat |
| Zuo-Long Liu, Miao Bian, Li Pan. LncRNA CRNDE Deteriorates Delayed Encephalopathy After Acute Carbon Monoxide Poisoning to Inactivate AKT/GSK3β/β-catenin Pathway via miR-212-5p. Neurotoxicity research. 2022-07-19. PMID:35852716. |
collectively, crnde, serving as a sponge of mir-212-5p, aggravated the injury and apoptosis of brain and hippocampus tissues through regulating akt/gsk3β/β-catenin signaling pathway under the co-poisoning and ogd-treated model, suggesting a selected therapeutic target of deacmp. |
2022-07-19 |
2023-08-14 |
rat |
| Behzad Garmabi, Reza Mohaddes, Fatemeh Rezvani, Fahimeh Mohseni, Hossein Khastar, Mehdi Khaksar. Erythropoietin improve spatial memory impairment following methamphetamine neurotoxicity by inhibition of apoptosis, oxidative stress and neuroinflammation in CA1 area of hippocampus. Journal of chemical neuroanatomy. 2022-07-16. PMID:35842017. |
erythropoietin improve spatial memory impairment following methamphetamine neurotoxicity by inhibition of apoptosis, oxidative stress and neuroinflammation in ca1 area of hippocampus. |
2022-07-16 |
2023-08-14 |
Not clear |
| Ramazan Çınar, Mustafa Nazıroğl. TRPM2 Channel Inhibition Attenuates Amyloid β42-Induced Apoptosis and Oxidative Stress in the Hippocampus of Mice. Cellular and molecular neurobiology. 2022-07-15. PMID:35840808. |
trpm2 channel inhibition attenuates amyloid β42-induced apoptosis and oxidative stress in the hippocampus of mice. |
2022-07-15 |
2023-08-14 |
mouse |
| Nazanin Mozafari, Jalal Hassanshahi, Hamid Ostadebrahimi, Ali Shamsizadeh, Fatemeh Ayoobi, Elham Hakimizadeh, Mohammad Pak-Hashemi, Ayat Kaeid. Neuroprotective effect of Achillea millefolium aqueous extract against oxidative stress and apoptosis induced by chronic morphine in rat hippocampal CA1 neurons. Acta neurobiologiae experimentalis. vol 82. issue 2. 2022-07-14. PMID:35833817. |
this study evaluates the neuroprotective effect of achillea millefolium (ach) on chronic morphine‑induced learning and memory impairment, oxidative stress, and neuronal apoptosis in the ca1 region of the rat hippocampus. |
2022-07-14 |
2023-08-14 |
human |
| Xiaoyan Ren, Jiangang Yu, Lili Guo, Zaili Zhan. CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway. Metabolic brain disease. 2022-07-12. PMID:35819709. |
cdgsh iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in ht22 hippocampal neurons by akt-nrf2-activated pathway. |
2022-07-12 |
2023-08-14 |
Not clear |
| Saereh Hosseindoost, Ardeshir Akbarabadi, Mitra-Sadat Sadat-Shirazi, Seyed M Mousavi, Solmaz Khalifeh, Azarakhsh Mokri, Mahmoudreza Hadjighassem, Mohammad-Reza Zarrindas. Effect of tramadol on apoptosis and synaptogenesis in hippocampal neurons: The possible role of µ-opioid receptor. Drug development research. 2022-07-09. PMID:35808942. |
effect of tramadol on apoptosis and synaptogenesis in hippocampal neurons: the possible role of µ-opioid receptor. |
2022-07-09 |
2023-08-14 |
rat |