| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Razie Mirjalili, Elahe Shokouh, Niloufar Sayah Dehkordi, Reza Afsari, Sakineh Shafia, Ali Rashidy-Pou. Prior short-term exercise prevents behavioral and biochemical abnormalities induced by single prolonged stress in a rat model of posttraumatic stress disorder. Behavioural brain research. 2022-04-11. PMID:35405172. |
sedentary male and female sps rats significantly (ps ranging <0.05 to <0.0001) exhibited increased anxiety levels in the elevated plus maze, enhanced serum corticosterone, reduced serum and hippocampal bdnf and enhanced hippocampal apoptosis than the corresponding control group. |
2022-04-11 |
2023-08-13 |
rat |
| Maryam Sabzali, Akram Eidi, Mehdi Khaksari, Hossein Khasta. Anti-inflammatory, Antioxidant, and Antiapoptotic Action of Metformin Attenuates Ethanol Neurotoxicity in the Animal Model of Fetal Alcohol Spectrum Disorders. Neurotoxicity research. 2022-04-07. PMID:35386022. |
in this study, we evaluated the protective effects of metformin on ethanol-related neuroinflammation, as well as neuron apoptosis in the hippocampus of adult male rat in animal model of fetal alcohol spectrum disorders. |
2022-04-07 |
2023-08-13 |
rat |
| Maryam Sabzali, Akram Eidi, Mehdi Khaksari, Hossein Khasta. Anti-inflammatory, Antioxidant, and Antiapoptotic Action of Metformin Attenuates Ethanol Neurotoxicity in the Animal Model of Fetal Alcohol Spectrum Disorders. Neurotoxicity research. 2022-04-07. PMID:35386022. |
in the metformin group, there was a reduction in cell apoptosis in the hippocampus, as well as gfap-positive cells (p < 0.01). |
2022-04-07 |
2023-08-13 |
rat |
| Xiaofang Wei, Juan Tan, Hui Ga. Role of sirtuin 1 in the brain development in congenital hypothyroidism rats via the regulation of p53 signaling pathway. Bioengineered. vol 13. issue 4. 2022-04-06. PMID:35383535. |
moreover, overexpression of sirt1 in the hippocampal tissues of rats with ch and improved rat behavior, while reducing the ch-induced nerve cell apoptosis. |
2022-04-06 |
2023-08-13 |
rat |
| Canelif Yilmaz, Thanasis Rogdakis, Alessia Latorrata, Evangelia Thanou, Eleftheria Karadima, Eleni Papadimitriou, Eleni Siapi, Ka Wan Li, Theodora Katsila, Theodora Calogeropoulou, Ioannis Charalampopoulos, Vasileia Ismini Alexak. ENT-A010, a Novel Steroid Derivative, Displays Neuroprotective Functions and Modulates Microglial Responses. Biomolecules. vol 12. issue 3. 2022-03-25. PMID:35327616. |
ent-a010 protected pc12 cells against serum starvation-induced cell death, dorsal root ganglia (drg) neurons against ngf deprivation-induced apoptosis and hippocampal neurons against aβ-induced apoptosis. |
2022-03-25 |
2023-08-13 |
mouse |
| Yamei Li, Bo Peng, Yi Li, Airu Huang, Yinian Peng, Qian Yu, Yufeng L. MiR-203a-3p/153-3p improves cognitive impairments induced by ischemia/reperfusion via blockade of SRC-mediated MAPK signaling pathway in ischemic stroke. Chemico-biological interactions. 2022-03-20. PMID:35305977. |
moreover, mir-203a-3p and mir-153-3p relieved the apoptosis, decreases nlrp3 inflammasome activity, decreases oxidative stress and inflammation in hippocampal neuron through targeting src. |
2022-03-20 |
2023-08-13 |
rat |
| Statement of Retraction: NF-κB signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via RCAN1 in neonatal rats with hypoxic-ischemic brain damage. Cell cycle (Georgetown, Tex.). 2022-03-17. PMID:35297309. |
statement of retraction: nf-κb signaling pathway inhibition suppresses hippocampal neuronal apoptosis and cognitive impairment via rcan1 in neonatal rats with hypoxic-ischemic brain damage. |
2022-03-17 |
2023-08-13 |
rat |
| Saeed Samarghandian, Fahimeh Ghasemi, Hamed Aramjoo, Fariborz Samini, Michael Aschner, Babak Roshanravan, Tahereh Farkhonde. Effects of exposure Toxicology reports. vol 9. 2022-03-14. PMID:35284239. |
our study indicated that bup may potentiate antioxidant system and inhibit apoptosis and oxidative stress in the hippocampus of neonates received this drug during the fetal stage. |
2022-03-14 |
2023-08-13 |
rat |
| Shi-Rong Lin, Qing-Ming Lin, Yu-Jia Lin, Xin Qian, Xiao-Ping Wang, Zheng Gong, Feng Chen, Bin Son. Bradykinin postconditioning protects rat hippocampal neurons after restoration of spontaneous circulation following cardiac arrest via activation of the AMPK/mTOR signaling pathway. Neural regeneration research. vol 17. issue 10. 2022-03-09. PMID:35259843. |
we found that bk postconditioning effectively promoted the recovery of rat neurological function after rosc following cardiac arrest, increased the amount of autophagosomes in the hippocampal tissue, inhibited neuronal cell apoptosis, up-regulated the expression of autophagy-related proteins lc3 and nbr1 and down-regulated p62, inhibited the expression of the brain injury marker s100β and apoptosis-related protein caspase-3, and affected the expression of adenosine monophosphate-activated protein kinase/mechanistic target of rapamycin pathway-related proteins. |
2022-03-09 |
2023-08-13 |
rat |
| Qi Zhang, Yanan Li, Chunping Yin, Jiaxu Yu, Juan Zhao, Lirong Yan, Qiujun Wan. Electro-Acupuncture Pretreatment Ameliorates Anesthesia and Surgery-Induced Cognitive Dysfunction Via Inhibiting Mitochondrial Injury and nEuroapoptosis in Aged Rats. Neurochemical research. 2022-03-08. PMID:35258777. |
then hippocampal tissues were stripped and hippocampal neuronal amount, expression level of cleaved caspase-9 level, cytochrome c (cyt c), cleaved caspase-3 level, bcl-2, bax, ros expression level, apoptosis rate, mitochondrial membrane potential (mmp), cytosolic calcium concentration ([ca |
2022-03-08 |
2023-08-13 |
rat |
| Yu-Lu Chen, Lei Tong, Yao Chen, Chang-Hai Fu, Jun-Bo Peng, Li-Li J. MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress. Experimental neurology. 2022-03-08. PMID:35259352. |
mir-153 downregulation alleviates ptsd-like behaviors and reduces cell apoptosis by upregulating the sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress. |
2022-03-08 |
2023-08-13 |
rat |
| Yu-Lu Chen, Lei Tong, Yao Chen, Chang-Hai Fu, Jun-Bo Peng, Li-Li J. MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress. Experimental neurology. 2022-03-08. PMID:35259352. |
furthermore, anti-mir-153 could also increase the dendritic spine density and reduce cell apoptosis in the hippocampus of sps rats. |
2022-03-08 |
2023-08-13 |
rat |
| Yu-Lu Chen, Lei Tong, Yao Chen, Chang-Hai Fu, Jun-Bo Peng, Li-Li J. MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress. Experimental neurology. 2022-03-08. PMID:35259352. |
the results of this study indicated that mir-153 might alleviate ptsd-like behaviors by regulating cell morphology and reducing cell apoptosis in the hippocampus of rats exposed to sps by targeting σ-1r, which might be related to the mtor signaling pathway. |
2022-03-08 |
2023-08-13 |
rat |
| Yujiao Yang, Debo Yun, Biqian Dong, Yuan Geng, Yong Wa. VIP alleviates sepsis-induced cognitive dysfunction as the TLR-4/NF-κB signaling pathway is inhibited in the hippocampus of rats. Journal of molecular histology. 2022-03-03. PMID:35239068. |
additionally, we examined apoptosis and inflammation in rats' hippocampus. |
2022-03-03 |
2023-08-13 |
rat |
| Yujiao Yang, Debo Yun, Biqian Dong, Yuan Geng, Yong Wa. VIP alleviates sepsis-induced cognitive dysfunction as the TLR-4/NF-κB signaling pathway is inhibited in the hippocampus of rats. Journal of molecular histology. 2022-03-03. PMID:35239068. |
it is worth noting that vip inhibited the apoptosis in the hippocampus and reduced the productions of proinflammatory cytokines tnf-α, il-6 and il-1β. |
2022-03-03 |
2023-08-13 |
rat |
| Zhu-Qing He, Peng-Fei Huan, Li Wang, Jian-Cheng H. Paeoniflorin ameliorates cognitive impairment in Parkinson's disease via JNK/p53 signaling. Metabolic brain disease. 2022-03-01. PMID:35230626. |
additionally, pf improved 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced neuronal injury by inhibiting apoptosis in hippocampal neurons of the ca1 and ca3, and upregulating psd-95 as well as syn protein levels. |
2022-03-01 |
2023-08-13 |
mouse |
| Asli Aykac, Kerem Teralı, Dilek Özbeyli, Seren Ede, Ömercan Albayrak, Kemal Hüsnü Can Başer, Göksel Şene. A multi-parameter evaluation of the neuroprotective and cognitive-enhancing effects of Origanum onites L. (Turkish Oregano) essential oil on scopolamine-induced amnestic rats. Metabolic brain disease. 2022-02-24. PMID:35201555. |
the observed effects could be attributed to inhibition of acetylcholinesterase activity, attenuation of oxidative stress and prevention of neuronal apoptosis in the hippocampus and frontal cortex of ad rats. |
2022-02-24 |
2023-08-13 |
rat |
| Monika Herian, Adam Wojtas, Marzena Maćkowiak, Agnieszka Wawrzczak-Bargiela, Anna Solarz, Agnieszka Bysiek, Katarzyna Madej, Krystyna Gołembiowsk. Neurotoxicological profile of the hallucinogenic compound 25I-NBOMe. Scientific reports. vol 12. issue 1. 2022-02-22. PMID:35190675. |
in this article 25i-nbome-crossing through the blood-brain barrier (bbb), the impact on dna damage, apoptosis induction, and changes in the number of cortical and hippocampal cells were studied. |
2022-02-22 |
2023-08-13 |
rat |
| Statement of Retraction: Silencing of PTEN inhibits the oxidative stress damage and hippocampal cell apoptosis induced by Sevoflurane through activating MEK1/ERK signaling pathway in infant rats. Cell cycle (Georgetown, Tex.). 2022-02-22. PMID:35191822. |
statement of retraction: silencing of pten inhibits the oxidative stress damage and hippocampal cell apoptosis induced by sevoflurane through activating mek1/erk signaling pathway in infant rats. |
2022-02-22 |
2023-08-13 |
rat |
| Behzad Dehqanizadeh, Ziya Fallah Mohammadi, Abdol Hossein Taheri Kalani, Seyed Javad Mirghan. Effect of Early Exercise on Inflammatory Parameters and Apoptosis in CA1 Area of the Hippocampus Following Cerebral Ischemia-reperfusion in Rats. Brain research bulletin. 2022-02-21. PMID:35189318. |
effect of early exercise on inflammatory parameters and apoptosis in ca1 area of the hippocampus following cerebral ischemia-reperfusion in rats. |
2022-02-21 |
2023-08-13 |
rat |