| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hui Yong, Gangming Wu, Jingyuan Chen, Xueru Liu, Yiping Bai, Ni Tang, Li Liu, Jicheng We. lncRNA MALAT1 Accelerates Skeletal Muscle Cell Apoptosis and Inflammatory Response in Sepsis by Decreasing BRCA1 Expression by Recruiting EZH2. Molecular therapy. Nucleic acids. vol 19. 2021-01-10. PMID:31830649. |
silencing lncrna malat1 resulted in reduced serum levels of interleukin (il)-6, il-8, and tumor necrosis factor alpha (tnf-α), neutrophil migration, skeletal muscle cell apoptosis, and akt-1 phosphorylation. |
2021-01-10 |
2023-08-13 |
mouse |
| Jing Li, Qiong Zhang, Weiwei Zeng, Yuxin Wu, Mei Luo, Yanhong Zhu, An-Yuan Guo, Xiangliang Yan. Integrating Transcriptome and Experiments Reveals the Anti-diabetic Mechanism of Cyclocarya paliurus Formula. Molecular therapy. Nucleic acids. vol 13. 2021-01-09. PMID:30388616. |
biochemical studies also demonstrated cpe treatment decreased pro-inflammatory cytokines (tumor necrosis factor alpha [tnf-α], interleukin [il]-1β, and il-6) and reduced β cell apoptosis. |
2021-01-09 |
2023-08-13 |
rat |
| Yu Tanaka, Akira Kuwahara, Kenjiro Ushigoe, Yuya Yano, Yuka Taniguchi, Yuri Yamamoto, Toshiya Matsuzaki, Toshiyuki Yasui, Minoru Irahar. Expression of cytokine-induced neutrophil chemoattractant suppresses tumor necrosis factor alpha expression and thereby prevents the follicles from undergoing atresia and apoptosis. Reproductive medicine and biology. vol 16. issue 2. 2021-01-09. PMID:29259464. |
expression of cytokine-induced neutrophil chemoattractant suppresses tumor necrosis factor alpha expression and thereby prevents the follicles from undergoing atresia and apoptosis. |
2021-01-09 |
2023-08-13 |
rat |
| Lifeng Jiang, Kai Xu, Jin Li, Xindie Zhou, Langhai Xu, Zhipeng Wu, Chiyuan Ma, Jisheng Ran, Pengfei Hu, Jiapeng Bao, Lidong Wu, Yan Xion. Nesfatin-1 suppresses interleukin-1β-induced inflammation, apoptosis, and cartilage matrix destruction in chondrocytes and ameliorates osteoarthritis in rats. Aging. vol 12. issue 2. 2021-01-08. PMID:32003758. |
the results showed that nesfatin-1 increased significantly the expression of collagen type ii alpha 1 chain (col2a1), and reduced the expression of mmps, adamts5, cyclooxygenase (cox)-2, caspase-3, nitric oxide (no), inducible nitric oxide synthase (inos), prostaglandin e2 (pge2), interleukin (il)-6, and chondrocyte apoptosis rate, which may be induced by il-1β in rat chondrocytes. |
2021-01-08 |
2023-08-13 |
rat |
| Ji Young Kim, Chan Hyung Kim, Eun Young Lee, Je Hoon Se. Alpha B-Crystallin Overexpression Protects Oligodendrocyte Precursor Cells Against Oxidative Stress-Induced Apoptosis Through the Akt Pathway. Journal of molecular neuroscience : MN. vol 70. issue 5. 2021-01-04. PMID:31970633. |
alpha b-crystallin overexpression protects oligodendrocyte precursor cells against oxidative stress-induced apoptosis through the akt pathway. |
2021-01-04 |
2023-08-13 |
Not clear |
| Feiyu Mao, Duguang Li, Zechang Xin, Yan Du, Xiaodong Wang, Peng Xu, Zhennan Li, Jianjun Qian, Jie Ya. High Expression of COL17A1 Predicts Poor Prognosis and Promotes the Tumor Progression via NF- Journal of oncology. vol 2020. 2021-01-01. PMID:33381179. |
high expression of col17a1 predicts poor prognosis and promotes the tumor progression via nf- col17a1 (collagen type xvii alpha 1 chain) is known to be upregulated and has a prognostic role in many malignancies, as well as contributing to cell proliferation, apoptosis, and invasion. |
2021-01-01 |
2023-08-13 |
Not clear |
| Wenfu Xu, Zhujun Wang, Kun Li, Runming Ji. Huai Qi Huang Potentiates Dexamethasone-Mediated Lethality in Acute Lymphoblastic Leukemia Cells by Upregulating Glucocorticoid Receptor α. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-12-11. PMID:32065117. |
results the results revealed that cell survival was reduced and apoptosis was increased as the hqh concentration was increased, and this was accompanied with increases in the levels of bax, cleaved-caspase-3 and glucocorticoid receptor alpha (gralpha) and decreases in the levels of bcl-2 and phospho-erk (perk). |
2020-12-11 |
2023-08-13 |
Not clear |
| Qiong Man, Yi Deng, Pengjie Li, Jun Ma, Zhijun Yang, Xiujuan Yang, Yan Zhou, Xiao Ya. Licorice Ameliorates Cisplatin-Induced Hepatotoxicity Through Antiapoptosis, Antioxidative Stress, Anti-Inflammation, and Acceleration of Metabolism. Frontiers in pharmacology. vol 11. 2020-11-27. PMID:33240085. |
the experimental results indicated that gc can recover functional indices and pathological liver injury, inhibit hepatocyte apoptosis, upregulate b-cell lymphoma/leukemia 2 (bcl-2) and superoxide dismutase (sod) levels, and downregulate cellular tumor antigen p53 (p53), caspase-3, malondialdehyde high mobility group protein b1 (hmgb1), tumor necrosis factor alpha (tnf-α), and interleukin 1β (il-1β) levels. |
2020-11-27 |
2023-08-13 |
Not clear |
| Geun-Young Kim, Hyun-Joung Lim, Won-Ho Kim, Hyun-Young Par. Coronin 1B regulates the TNFα-induced apoptosis of HUVECs by mediating the interaction between TRADD and FADD. Biochemical and biophysical research communications. vol 526. issue 4. 2020-11-24. PMID:32303335. |
however, the role of coronin 1b in tumor necrosis factor alpha (tnfα)-induced endothelial cell apoptosis remained unknown. |
2020-11-24 |
2023-08-13 |
human |
| Soo-Min Kim, Kyung-Chul Cho. Acrylonitrile induced cell cycle arrest and apoptosis by promoting the formation of reactive oxygen species in human choriocarcinoma cells. The Journal of toxicological sciences. vol 45. issue 11. 2020-11-23. PMID:33132245. |
moreover, western blot assay confirmed that an treatment of jeg-3 and bewo cells for 4 hr promoted the expression of phosphorylated eukaryotic initiation factor 2 alpha protein (p-eif2α), c/ebp homologous protein (chop) and caspase 12, which are known to be involved in ros-mediated endoplasmic reticulum stress (er-stress)-related apoptosis. |
2020-11-23 |
2023-08-13 |
human |
| Shan Xiao, Yanping Wang, Yuwen Ma, Jue Liu, Can'e Tang, Aiping Deng, Chunxiang Fan. Dimethylation of eEF1A at Lysine 55 Plays a Key Role in the Regulation of eEF1A2 on Malignant Cell Functions of Acute Myeloid Leukemia. Technology in cancer research & treatment. vol 19. 2020-11-20. PMID:32347192. |
this study aimed to explore whether eukaryotic translation elongation factor 1 alpha 2 affected cell proliferation, migration, and apoptosis via regulating the dimethylation of eukaryotic translation elongation factor 1 alpha at lysine 55 in acute myeloid leukemia. |
2020-11-20 |
2023-08-13 |
Not clear |
| Yu Feng, Qingchu Li, Yinxiang Wu, Nana Zhao, Lu Li, Li Li, Liming Zha. Blocking C/EBP β protects vascular endothelial cells from injury induced by intermittent hypoxia. Sleep & breathing = Schlaf & Atmung. vol 23. issue 3. 2020-11-02. PMID:30680681. |
hypoxia induces apoptosis in endothelial cells via upregulation of endothelin-1 (et-1) and hypoxia inducible factor-1 alpha (hif-1α) plays a key role in the hypoxic stress response. |
2020-11-02 |
2023-08-13 |
Not clear |
| Wenwei Jiang, Xinyu Cai, Tianyang Xu, Kaiyuan Liu, Dong Yang, Lin Fan, Guodong Li, Xiao Y. Tripartite Motif-Containing 46 Promotes Viability and Inhibits Apoptosis of Osteosarcoma Cells by Activating NF-B Signaling Through Ubiquitination of PPAR. Oncology research. vol 28. issue 4. 2020-10-28. PMID:32295675. |
trim46 knockdown inhibits os cell viability and cell cycle progression and induces apoptosis, while trim46 overexpression exerts inverse effects, which are inhibited by peroxisome proliferator-activated receptor alpha (ppar) overexpression and the nuclear factor kappa b (nf-b) inhibitor, pyrrolidine dithiocarbamate (pdtc). |
2020-10-28 |
2023-08-13 |
Not clear |
| Núria Arcarons, Meritxell Vendrell-Flotats, Marc Yeste, Elena Mercade, Manel López-Béjar, Teresa Moga. Cryoprotectant role of exopolysaccharide of Pseudomonas sp. ID1 in the vitrification of IVM cow oocytes. Reproduction, fertility, and development. vol 31. issue 9. 2020-10-19. PMID:31092307. |
however, supplementation with 10 and 100µgml-1 eps id1 led to increased expression of genes involved in epigenetic modifications (dna methyltransferase 3 alpha (dnmt3a) and k (lysine) acetyltransferase 2a (kat2a)) and apoptosis (bcl2 associated x apoptosis regulator (bax) and bcl2-like 1 (bcl2l1)). |
2020-10-19 |
2023-08-13 |
cattle |
| Shawn T Beug, Stephanie J Pichette, Martine St-Jean, Janelle Holbrook, Danielle E Walker, Eric C LaCasse, Robert G Kornelu. Combination of IAP Antagonists and TNF-α-Armed Oncolytic Viruses Induce Tumor Vascular Shutdown and Tumor Regression. Molecular therapy oncolytics. vol 10. 2020-10-01. PMID:30101187. |
smac mimetic compounds (smcs) are anti-cancer drugs that antagonize inhibitor of apoptosis proteins, which consequently sensitize cancer cells to death in the presence of proinflammatory ligands such as tumor necrosis factor alpha (tnf-α). |
2020-10-01 |
2023-08-13 |
Not clear |
| Chen Qian, Zhongluan Wu, Roy Chun-Laam Ng, Maria-Mercè Garcia-Barceló, Zheng-Wei Yuan, Kenneth Kak Yuen Wong, Paul Kwong Hang Tam, Vincent Chi Hang Lu. Conditional deletion of platelet derived growth factor receptor alpha (Pdgfra) in urorectal mesenchyme causes mesenchyme apoptosis and urorectal developmental anomalies in mice. Cell death and differentiation. vol 26. issue 8. 2020-10-01. PMID:30323271. |
conditional deletion of platelet derived growth factor receptor alpha (pdgfra) in urorectal mesenchyme causes mesenchyme apoptosis and urorectal developmental anomalies in mice. |
2020-10-01 |
2023-08-13 |
mouse |
| Shasha Song, Liang Chu, Huifang Liang, Jin Chen, Junnan Liang, Zhao Huang, Bixiang Zhang, Xiaoping Che. Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31572199. |
in this study, the results showed that dioscin significantly ameliorated dox-induced cell injury, reduced reactive oxygen species (ros) level, and suppressed cell apoptosis in alpha mouse liver 12 (aml-12) cells caused by dox. |
2020-10-01 |
2023-08-13 |
mouse |
| Xiao Wu, Meng-Yao Wu, Min Jiang, Qiaoming Zhi, Xiaojie Bian, Meng-Dan Xu, Fei-Ran Gong, Juan Hou, Min Tao, Liu-Mei Shou, Weiming Duan, Kai Chen, Meng Shen, Wei L. TNF-α sensitizes chemotherapy and radiotherapy against breast cancer cells. Cancer cell international. vol 17. 2020-10-01. PMID:28127258. |
tumor necrosis factor alpha (tnf-α) exerts multiple functions in cell proliferation, differentiation and apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Altaf A Kondkar, Tahira Sultan, Faisal A Almobarak, Hatem Kalantan, Saleh A Al-Obeidan, Khaled K Abu-Amer. Association of increased levels of plasma tumor necrosis factor alpha with primary open-angle glaucoma. Clinical ophthalmology (Auckland, N.Z.). vol 12. 2020-10-01. PMID:29695893. |
elevated levels of tumor necrosis factor alpha (tnf-α), a pro-inflammatory cytokine, can induce rgc apoptosis and play a critical role in glaucomatous neurodegeneration. |
2020-10-01 |
2023-08-13 |
Not clear |
| Rosalba D'Alessandro, Maria Grazia Refolo, Palma Aurelia Iacovazzi, Pasqua Letizia Pesole, Caterina Messa, Brian Irving Car. Ramucirumab and GSK1838705A Enhance the Inhibitory Effects of Low Concentration Sorafenib and Regorafenib Combination on HCC Cell Growth and Motility. Cancers. vol 11. issue 6. 2020-09-30. PMID:31181647. |
in these experimental conditions cell growth and migration were potently inhibited and apoptosis induced even in hcc cells producing high alpha fetoprotein (afp) levels (clinically worse prognosis). |
2020-09-30 |
2023-08-13 |
Not clear |