| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vyron A Gorgogietas, Ioannis Tsialtas, Natalie Sotiriou, Vasiliki C Laschou, Aikaterini G Karra, Demetres D Leonidas, George P Chrousos, Evagelia Protopapa, Anna-Maria G Psarr. Potential interference of aluminum chlorohydrate with estrogen receptor signaling in breast cancer cells. Journal of molecular biochemistry. vol 7. issue 1. 2020-09-29. PMID:30148119. |
moreover, ach caused increase in the perinuclear localization of estrogen receptor alpha in mcf-7 breast cancer cells and increase in the mitochondrial bcl-2 protein, possibly affecting receptors-mediated mitochondrial actions and mitochondrial-dependent apoptosis. |
2020-09-29 |
2023-08-13 |
Not clear |
| Chrysoula-Evangelia Karachaliou, Ioannis V Kostopoulos, Vyronia Vassilakopoulou, Persefoni Klimentzou, Maria Paravatou-Petsotas, Wolfgang Voelter, Hubert Kalbacher, Christos Zikos, Ourania Tsitsilonis, Evangelia Livanio. Development of a specific IgY-based ELISA for prothymosin alpha, a bioactive polypeptide with diagnostic and therapeutic potential. Heliyon. vol 5. issue 10. 2020-09-29. PMID:31720448. |
prothymosin alpha (protα) is a highly conserved polypeptide (109 amino acids in humans) with diagnostic and therapeutic potential; protα exerts intra- and extra-cellular biological functions associated with cell proliferation, apoptosis and immune regulation, while it has been suggested to act as a damage-associated molecular pattern (damp) or alarmin. |
2020-09-29 |
2023-08-13 |
chicken |
| Meng-Ru Wang, Xiao-Jian Zhang, Hong-Chun Liu, Wen-Di Ma, Ming-Liang Zhang, Yuan Zhang, Xing Li, Meng-Meng Dou, Yi-Lei Jing, Yao-Juan Chu, Lin Zh. Matrine protects oligodendrocytes by inhibiting their apoptosis and enhancing mitochondrial autophagy. Brain research bulletin. vol 153. 2020-09-24. PMID:31404585. |
in the present study, we show that mat effectively suppressed ongoing eae, and significantly reduced the expression of caspase-3 and alpha b-crystallin in olgs, therefore lessen olg apoptosis, microglial activation and inflammatory factors secretion. |
2020-09-24 |
2023-08-13 |
Not clear |
| Jaw Long Sun, A M Abd El-Aty, Ji Hoon Jeong, Tae Woo Jun. Ginsenoside Rb2 Ameliorates LPS-Induced Inflammation and ER Stress in HUVECs and THP-1 Cells via the AMPK-Mediated Pathway. The American journal of Chinese medicine. vol 48. issue 4. 2020-09-17. PMID:32431178. |
concentrations of tumor necrosis factor alpha (tnf[formula: see text]) and monocyte chemoattractant protein-1 (mcp-1) in culture media were assessed by enzyme-linked immunosorbent assay (elisa) and apoptosis was evaluated by a cell viability assay and a caspase-3 activity measurement kit. |
2020-09-17 |
2023-08-13 |
Not clear |
| Huihui Jiang, Peili Hou, Hongbin He, Hongmei Wan. Cell apoptosis regulated by interaction between viral gene alpha 3 and host heterogeneous nuclear ribonucleoprotein K facilitates bovine ephemeral fever virus replication. Veterinary microbiology. vol 240. 2020-09-16. PMID:31902512. |
cell apoptosis regulated by interaction between viral gene alpha 3 and host heterogeneous nuclear ribonucleoprotein k facilitates bovine ephemeral fever virus replication. |
2020-09-16 |
2023-08-13 |
cattle |
| Duo Peng, Meili Lv, Zhilong Li, Huan Tian, ShengQiu Qu, Bo Jin, Bing Long, Weibo Liang, Lin Zhan. Postmortem interval determination using mRNA markers and DNA normalization. International journal of legal medicine. vol 134. issue 1. 2020-09-14. PMID:31773316. |
we then coextracted the dna and rna in one tube with bioteke coextraction kits and selected some mrna markers associated with cell oxygen deprivation and apoptosis as target genes, such as hypoxia-associated factor (haf), apoptosis-inducing factor (aif), hypoxia-inducible factor 2 alpha (hif2a), and factor inhibiting hif (fih). |
2020-09-14 |
2023-08-13 |
mouse |
| Shunsuke Uchida, Mierxiati Saimi, Zhong-Lian Li, Hidenobu Miyaso, Kenta Nagahori, Shinichi Kawata, Takuya Omotehara, Yuki Ogawa, Masahiro Ito. Effects of phosphorylated estrogen receptor alpha on apoptosis in human endometrial epithelial cells. Anatomical science international. vol 95. issue 2. 2020-09-11. PMID:31823335. |
effects of phosphorylated estrogen receptor alpha on apoptosis in human endometrial epithelial cells. |
2020-09-11 |
2023-08-13 |
human |
| Li Wenzhao, Ni Jiangdong, Song Deye, Ding Muliang, Wang Junjie, Huang Xianzhe, Yan Mingming, Huang Ju. Dual regulatory roles of HMGB1 in inflammatory reaction of chondrocyte cells and mice. Cell cycle (Georgetown, Tex.). vol 18. issue 18. 2020-09-01. PMID:31313630. |
in the current study, we used quantitative real-time pcr(q-pcr) to detect them rna levels of collagen type ii alpha 1(col2a1), aggrecan, mmp3(matrix metallopeptidase 3), mmp13, adamts4 and adamts5; enzyme-linked immunosorbent assay(elisa) was used to detect the content of il-1β and calpain protein; cell apoptosis was evaluated by terminal deoxynucleotidyl transferase-mediated dutp-biotin nick end labeling(tunel) assay and flow cytometryanalysis; western blot and immunofluorescence assays were applied to assess the expression of hmgb1; lastly autophagic activity was mainly verified by monodansylcadaverine (mdc) staining. |
2020-09-01 |
2023-08-13 |
mouse |
| Da-Peng Wang, Hang Yin, Qi Lin, Shu-Ping Fang, Jian-Hua Shen, Yi-Fang Wu, Shao-Hua Su, Jian Ha. Andrographolide enhances hippocampal BDNF signaling and suppresses neuronal apoptosis, astroglial activation, neuroinflammation, and spatial memory deficits in a rat model of chronic cerebral hypoperfusion. Naunyn-Schmiedeberg's archives of pharmacology. vol 392. issue 10. 2020-08-31. PMID:31187188. |
astrocyte activation was examined by immunohistochemical staining and western blotting for glial fibrillary acid protein (gfap), while expression levels of the pro-inflammatory cytokine-tumor necrosis factor alpha (tnf-α) and interleukin 1 beta (il-1β), the apoptosis effector cysteinyl aspartate specific proteinase-3 (caspase-3), and the neuroprotectant brain-derived neurotrophic factor (bdnf) and the trkb receptor were estimated by western blotting. |
2020-08-31 |
2023-08-13 |
rat |
| Robyn A Wong, Xujun Luo, Mimi Lu, Zhenyi An, Daphne A Haas-Kogan, Joanna J Phillips, Kevan M Shokat, William A Weiss, Qi Wen Fa. Cooperative Blockade of PKCα and JAK2 Drives Apoptosis in Glioblastoma. Cancer research. vol 80. issue 4. 2020-08-21. PMID:31806641. |
apoptosis induced by pp242 resulted from off-target cooperative inhibition of jak2 and protein kinase c alpha (pkcα). |
2020-08-21 |
2023-08-13 |
human |
| Dong-Kyu Kim, Seung Ah Choi, Kyoung Mi Eun, Seung-Ki Kim, Dae Woo Kim, Ji Hoon Ph. Tumour necrosis factor alpha and interleukin-5 inhibit olfactory regeneration via apoptosis of olfactory sphere cells in mice models of allergic rhinitis. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. vol 49. issue 8. 2020-08-19. PMID:30980570. |
tumour necrosis factor alpha and interleukin-5 inhibit olfactory regeneration via apoptosis of olfactory sphere cells in mice models of allergic rhinitis. |
2020-08-19 |
2023-08-13 |
mouse |
| Dayong Xia, Xiaofu Zhai, Honglian Wang, Zhiyong Chen, Chuanjing Fu, Meihua Zh. Alpha lipoic acid inhibits oxidative stress-induced apoptosis by modulating of Nrf2 signalling pathway after traumatic brain injury. Journal of cellular and molecular medicine. vol 23. issue 6. 2020-07-31. PMID:30989783. |
alpha lipoic acid inhibits oxidative stress-induced apoptosis by modulating of nrf2 signalling pathway after traumatic brain injury. |
2020-07-31 |
2023-08-13 |
rat |
| Wei-Huang Liu, Qiao-Na Wang, Ying Zhou, Yan-Jun Wang, Zan Ton. Divergent effects of lycopene on pancreatic alpha and beta cells. Sheng li xue bao : [Acta physiologica Sinica]. vol 72. issue 2. 2020-07-30. PMID:32328606. |
in this study, different concentrations of lycopene were used to treat pancreatic alpha and beta cell lines, and the changes of cell growth, cell apoptosis, cell cycle, reactive oxygen species (ros), atp levels and expression of related cytokines were determined. |
2020-07-30 |
2023-08-13 |
Not clear |
| Wei-Huang Liu, Qiao-Na Wang, Ying Zhou, Yan-Jun Wang, Zan Ton. Divergent effects of lycopene on pancreatic alpha and beta cells. Sheng li xue bao : [Acta physiologica Sinica]. vol 72. issue 2. 2020-07-30. PMID:32328606. |
the results exhibited that lycopene did not affect cell growth, cell apoptosis, cell cycle, ros and atp levels of alpha cells, while it promoted the growth of beta cells, increased the ratio of s phase, reduced the ros levels and increased the atp levels of beta cells. |
2020-07-30 |
2023-08-13 |
Not clear |
| Philipp Y Maximov, Balkees Abderrahman, Yousef M Hawsawi, Yue Chen, Charles E Foulds, Antrix Jain, Anna Malovannaya, Ping Fan, Ramona F Curpan, Ross Han, Sean W Fanning, Bradley M Broom, Daniela M Quintana Rincon, Jeffery A Greenland, Geoffrey L Greene, V Craig Jorda. The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells. Molecular pharmacology. vol 98. issue 1. 2020-07-30. PMID:32362585. |
the structure-function relationship of angular estrogens and estrogen receptor alpha to initiate estrogen-induced apoptosis in breast cancer cells. |
2020-07-30 |
2023-08-13 |
Not clear |
| Xiaobao Fan, Zhenjiang Li, Xiaoming Wang, Jing Wang, Zhiming Ha. Silencing of KPNA2 inhibits high glucose-induced podocyte injury via inactivation of mTORC1/p70S6K signaling pathway. Biochemical and biophysical research communications. vol 521. issue 4. 2020-07-27. PMID:31727365. |
it has been reported that karyopherin alpha 2 (kpna2) contributes to apoptosis and autophagy in various cells, but its role in dn development remains unknown. |
2020-07-27 |
2023-08-13 |
Not clear |
| Touseef Rehan, David MacEwan, Nasrullah Shah, Tabassum Rehan, Riffat Tahira, Sheeba Murad, Mariam Anees, Iram Murtaza, Muhammad Farman, Obaid-Ur-Rahman Abid, Aneesa Sulta. Apoptosis of Leukemia Cells by Ocimum basilicum Fractions Following TNF alpha Induced Activation of JNK and Caspase 3. Current pharmaceutical design. vol 25. issue 34. 2020-06-15. PMID:31604407. |
apoptosis of leukemia cells by ocimum basilicum fractions following tnf alpha induced activation of jnk and caspase 3. |
2020-06-15 |
2023-08-13 |
Not clear |
| Mingzheng Peng, Lei Qiang, Yan Xu, Cuidi Li, Tao Li, Jinwu Wan. IL-35 ameliorates collagen-induced arthritis by promoting TNF-α-induced apoptosis of synovial fibroblasts and stimulating M2 macrophages polarization. The FEBS journal. vol 286. issue 10. 2020-05-22. PMID:30834683. |
in this study, we investigated the effect of il-35 on the cia microenvironment and, specifically, the tumor necrosis factor alpha (tnf-α)-induced macrophage inflammatory response and apoptosis of fibroblast-like synoviocytes (flss). |
2020-05-22 |
2023-08-13 |
mouse |
| Neena Lala-Tabbert, Rim Lejmi-Mrad, Kristen Timusk, Marina Fukano, Janelle Holbrook, Martine St-Jean, Eric C LaCasse, Robert G Kornelu. Targeted ablation of the cellular inhibitor of apoptosis 1 (cIAP1) attenuates denervation-induced skeletal muscle atrophy. Skeletal muscle. vol 9. issue 1. 2020-05-04. PMID:31126323. |
the cellular inhibitor of apoptosis 1 (ciap1) protein is a positive regulator of tumor necrosis factor alpha (tnfα)-mediated classical nf-κb signaling, and ciap1 loss has been shown to enhance muscle regeneration during acute and chronic injury. |
2020-05-04 |
2023-08-13 |
Not clear |
| Tomonaga Ichikawa, Obeid Shanab, Shingo Nakahata, Shunsuke Shimosaki, Nawin Manachai, Masaya Ono, Hidekatsu Iha, Kazuya Shimoda, Kazuhiro Morishit. Novel PRMT5-mediated arginine methylations of HSP90A are essential for maintenance of HSP90A function in NDRG2 Biochimica et biophysica acta. Molecular cell research. vol 1867. issue 2. 2020-04-20. PMID:31765670. |
to investigate how the apoptosis is induced by the knockdown prmt5 expression, heat shock protein 90 alpha (hsp90a) was identified as a binding protein for ndrg2 or prmt5 by immunoprecipitation-mass analysis. |
2020-04-20 |
2023-08-13 |
human |