| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Neslihan Çoban, Çağrı Güleç, Bilge Özsait Selçuk, Nihan Erginel-Ünaltun. Role of simvastatin and RORα activity in the macrophage apoptotic pathway. Anatolian journal of cardiology. vol 17. issue 5. 2019-04-18. PMID:28613211. |
this study was conducted to explore the effects of simvastatin and retinoic acid receptor-related orphan receptor alpha (rorα) ligands on apoptosis in human acute monocytic leukemia (thp-1) macrophage cells. |
2019-04-18 |
2023-08-13 |
human |
| Marie Ménard, Clélia Costechareyre, Gabriel Ichim, Jonathan Blachier, David Neves, Loraine Jarrosson-Wuilleme, Reinhard Depping, Jan Koster, Pierre Saintigny, Patrick Mehlen, Servane Tauszig-Delamasur. Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth. PLoS biology. vol 16. issue 5. 2019-04-18. PMID:29750782. |
by investigating interacting partners that might facilitate trkc-induced cell death, we have identified the basic helix-loop-helix (bhlh) transcription factor hey1 and importin-α3 (karyopherin alpha 4 [kpna4]) as direct interactors of trkc intracellular domain, and we show that hey1 is required for trkc-induced apoptosis. |
2019-04-18 |
2023-08-13 |
mouse |
| Gabriel H Campolina-Silva, Rex A Hess, Cleida A Oliveir. Seasonal variation of cell proliferation and apoptosis in the efferent ductules and epididymis of the Neotropical bat Artibeus lituratus (Chiroptera, Phyllostomidae). General and comparative endocrinology. vol 273. 2019-04-08. PMID:29427632. |
the increased proliferative activity at this phase was positively correlated with the expression of estrogen receptor alpha (erα), whereas the variation in apoptosis appears to be unrelated to the local expression of androgen and estrogen receptors. |
2019-04-08 |
2023-08-13 |
Not clear |
| Kathryn Ondricek, Peter Thoma. Effects of hypoxia exposure on apoptosis and expression of membrane steroid receptors, ZIP9, mPRα, and GPER in Atlantic croaker ovaries. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 224. 2019-04-05. PMID:30025815. |
conversely, apoptosis is inhibited in these cells by non-classical steroid mechanisms through membrane progestin receptor alpha (mprα) and g protein-coupled estrogen receptor (gper). |
2019-04-05 |
2023-08-13 |
Not clear |
| Miran Rada, Sameera Nallanthighal, Jennifer Cha, Kerry Ryan, Jessica Sage, Catherine Eldred, Maria Ullo, Sandra Orsulic, Dong-Joo Cheo. Inhibitor of apoptosis proteins (IAPs) mediate collagen type XI alpha 1-driven cisplatin resistance in ovarian cancer. Oncogene. vol 37. issue 35. 2019-02-27. PMID:29769618. |
inhibitor of apoptosis proteins (iaps) mediate collagen type xi alpha 1-driven cisplatin resistance in ovarian cancer. |
2019-02-27 |
2023-08-13 |
mouse |
| Xinrui Zhao, Lidong Liu, Rui Li, Xuan Wei, Wenqing Luan, Peishu Liu, Jing Zha. Hypoxia-Inducible Factor 1-α (HIF-1α) Induces Apoptosis of Human Uterosacral Ligament Fibroblasts Through the Death Receptor and Mitochondrial Pathways. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2019-02-13. PMID:30504760. |
cell apoptosis and expression of apoptosis-associated proteins and collagen type i alpha 1 (col1a1) were measured by flow cytometry, tunel and western blot, respectively. |
2019-02-13 |
2023-08-13 |
human |
| Leah Persaud, Jason Mighty, Xuelin Zhong, Ashleigh Francis, Marifer Mendez, Hilal Muharam, Stephen M Redenti, Dibash Das, Bertal Huseyin Aktas, Moira Sauan. IL-24 Promotes Apoptosis through cAMP-Dependent PKA Pathways in Human Breast Cancer Cells. International journal of molecular sciences. vol 19. issue 11. 2019-02-08. PMID:30424508. |
we have shown that il-24 regulates apoptosis through phosphorylated eukaryotic initiation factor 2 alpha (eif2α) during endoplasmic reticulum (er) stress in cancer. |
2019-02-08 |
2023-08-13 |
human |
| Sang-Soo Kim, Antonina Rait, Emilio R Garrido-Sanabria, Kathleen F Pirollo, Joe B Harford, Esther H Chan. Nanotherapeutics for Gene Modulation that Prevents Apoptosis in the Brain and Fatal Neuroinflammation. Molecular therapy : the journal of the American Society of Gene Therapy. vol 26. issue 1. 2019-01-15. PMID:29103910. |
as proof of concept for the therapeutic potential of our delivery system, we employed scl delivering an sirna targeting tumor necrosis factor alpha to suppress neuroinflammation and neuronal apoptosis and to protect mice in lethal endotoxemia triggered by bacterial lipopolysaccharide. |
2019-01-15 |
2023-08-13 |
mouse |
| Li-Li Liu, Dahu Li, Yun-Ling He, Yan-Zhao Zhou, Sheng-Hui Gong, Li-Ying Wu, Yong-Qi Zhao, Xin Huang, Tong Zhao, Lun Xu, Kui-Wu Wu, Ming-Gao Li, Ling-Ling Zhu, Ming Fa. miR-210 protects renal cell against hypoxia-induced apoptosis by targeting HIF-1 alpha. Molecular medicine (Cambridge, Mass.). vol 23. 2019-01-04. PMID:29387863. |
mir-210 protects renal cell against hypoxia-induced apoptosis by targeting hif-1 alpha. |
2019-01-04 |
2023-08-13 |
human |
| Shugo Suzuki, Samuel M Cohen, Lora L Arnold, Hiroyuki Kato, Satoshi Fuji, Karen L Pennington, Yuko Nagayasu, Aya Naiki-Ito, Yoriko Yamashita, Satoru Takahash. Orally administered nicotine effects on rat urinary bladder proliferation and carcinogenesis. Toxicology. vol 398-399. 2018-12-28. PMID:29501575. |
ki67 and pstat3 labeling indices and expression of nicotinic acetylcholine receptor alpha 7 (nachrα7) in non-tumor bladder urothelial lesions were significantly increased by nicotine, but the tunel assay for apoptosis showed no increase. |
2018-12-28 |
2023-08-13 |
mouse |
| Jinghan Wang, Yuan Sun, Xing-Yu Meng, Lian-Feng Li, Yongfeng Li, Yuzi Luo, Wenjing Wang, Shaoxiong Yu, Caixia Yin, Su Li, Hua-Ji Qi. Comprehensive evaluation of the host responses to infection with differentially virulent classical swine fever virus strains in pigs. Virus research. vol 255. 2018-12-18. PMID:29953916. |
furthermore, leukopenia, lymphocytopenia, differentiation of t-cells, and the secretion of cytokines associated with inflammation or apoptosis such as interferon alpha (ifn-α), tumor necrosis factor alpha (tnf-α), interleukin 2 (il-2), il-4, il-6, and il-10 were induced by the virulent csfv infection, the differences reflected in onset and extent of the regulation. |
2018-12-18 |
2023-08-13 |
Not clear |
| Ramasamy Karthikeyan, Govindasamy Kanimozhi, Nagarajan Rajendra Prasad, Balupillai Agilan, Muthusamy Ganesan, Gunaseelan Sritha. Alpha pinene modulates UVA-induced oxidative stress, DNA damage and apoptosis in human skin epidermal keratinocytes. Life sciences. vol 212. 2018-12-14. PMID:30292828. |
alpha pinene modulates uva-induced oxidative stress, dna damage and apoptosis in human skin epidermal keratinocytes. |
2018-12-14 |
2023-08-13 |
human |
| Daniel E Rensetti, Maia S Marin, Pedro E Morán, Anselmo C Odeón, Andrea E Verna, Sandra E Pére. Bovine herpesvirus type 5 replication and induction of apoptosis in vitro and in the trigeminal ganglion of experimentally-infected cattle. Comparative immunology, microbiology and infectious diseases. vol 57. 2018-10-30. PMID:30017083. |
these findings suggest that the induction of apoptosis and the innate immune response orchestrate the final outcome of alpha herpesviruses infection of the bovine nervous system. |
2018-10-30 |
2023-08-13 |
cattle |
| Young Sik Ch. The role of necroptosis in the treatment of diseases. BMB reports. vol 51. issue 5. 2018-10-01. PMID:29636122. |
necroptosis is mainly unmasked when apoptosis is compromised in response to tumor necrosis factor alpha. |
2018-10-01 |
2023-08-13 |
Not clear |
| Xiao-Ping Liu, Xiao-Hong Yin, Xin-Hui Yan, Xian-Tao Zeng, Xing-Huan Wan. The Clinical Relevance of Fragile Histidine Triad Protein (FHIT) in Patients with Bladder Cancer. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-10-01. PMID:29752880. |
gsea results indicated that bc samples in the fhit low expression group were enriched in interferon alpha response, apoptosis, androgen response, interferon gamma response, heme metabolism, and transforming growth facto r(tgf) beta signaling. |
2018-10-01 |
2023-08-13 |
Not clear |
| X W Dong, Z H Zheng, J Ding, X Luo, Z Q Li, Y Li, M Y Rong, Y L Fu, J H Shi, L C Yu, Z B Wu, P Zh. Combined detection of uMCP-1 and uTWEAK for rapid discrimination of severe lupus nephritis. Lupus. vol 27. issue 6. 2018-09-25. PMID:29451067. |
to determine a better tool for kidney damage detection, the present study compared the evaluation ability of novel urinary cytokines and chemokines (namely urinary monocyte chemoattractant protein 1 (umcp-1), tumor necrosis factor-like weak inducer of apoptosis (utweak)) with traditional serum or urinary markers (namely urinary alpha 1-microgrobulin (uα1-mg), beta 2-microglobulin (uβ2-mg) and serum complement c3 (c3), complement c4 (c4), creatinine (cr), blood urea nitrogen (bun) and cystatin c (cys c)) in discriminating ln renal damage. |
2018-09-25 |
2023-08-13 |
Not clear |
| M Bu. New biological agents in the treatment of multiple sclerosis. Bratislavske lekarske listy. vol 119. issue 4. 2018-09-11. PMID:29663814. |
they are represented by monoclonal antibodies binding to molecules vla4 (natalizumab), cd20 (ocrelizumab), cd52 (alemtuzumab) or alpha subunit of il-2 receptor (daclizumab) or by small molecules such as those modulating the receptors involved in regulation of lymphocyte migration (fingolimod, ozanimod) or in induction of lymphopenia by apoptosis (dimethyl fumarate, cladribine). |
2018-09-11 |
2023-08-13 |
Not clear |
| Bih-Cheng Chen, Yi-Jiun Weng, Marthandam Asokan Shibu, Chien-Kuo Han, Yueh-Sheng Chen, Chia-Yao Shen, Yueh-Min Lin, Vijaya Padma Viswanadha, Hsin-Yueh Liang, Chih-Yang Huan. Estrogen and/or Estrogen Receptor α Inhibits BNIP3-Induced Apoptosis and Autophagy in H9c2 Cardiomyoblast Cells. International journal of molecular sciences. vol 19. issue 5. 2018-09-11. PMID:29701696. |
estrogen (e2) and estrogen receptor (er) alpha (erα) have been shown to protect the heart against mitochondria-dependent apoptosis. |
2018-09-11 |
2023-08-13 |
Not clear |
| Bih-Cheng Chen, Yi-Jiun Weng, Marthandam Asokan Shibu, Chien-Kuo Han, Yueh-Sheng Chen, Chia-Yao Shen, Yueh-Min Lin, Vijaya Padma Viswanadha, Hsin-Yueh Liang, Chih-Yang Huan. Estrogen and/or Estrogen Receptor α Inhibits BNIP3-Induced Apoptosis and Autophagy in H9c2 Cardiomyoblast Cells. International journal of molecular sciences. vol 19. issue 5. 2018-09-11. PMID:29701696. |
the aim of the present study is to investigate the mechanisms by which erα regulates bnip3-induced apoptosis and autophagy, which is associated with hypoxic injury, in cardiomyoblast cells. |
2018-09-11 |
2023-08-13 |
Not clear |
| Bih-Cheng Chen, Yi-Jiun Weng, Marthandam Asokan Shibu, Chien-Kuo Han, Yueh-Sheng Chen, Chia-Yao Shen, Yueh-Min Lin, Vijaya Padma Viswanadha, Hsin-Yueh Liang, Chih-Yang Huan. Estrogen and/or Estrogen Receptor α Inhibits BNIP3-Induced Apoptosis and Autophagy in H9c2 Cardiomyoblast Cells. International journal of molecular sciences. vol 19. issue 5. 2018-09-11. PMID:29701696. |
further, the effects of e2 and erα in bnip3-induced apoptosis and autophagy were determined in bnip3 expressing h9c2 cells. |
2018-09-11 |
2023-08-13 |
Not clear |