| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Soo-Min Kim, Hae-Miru Lee, Kyung-A Hwang, Kyung-Chul Cho. Benzo(a)pyrene induced cell cycle arrest and apoptosis in human choriocarcinoma cancer cells through reactive oxygen species-induced endoplasmic reticulum-stress pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 107. issue Pt A. 2018-01-23. PMID:28673838. |
wb assay also confirmed that each b(a)p treatment of jeg-3 and bewo cells for 4 h promoted the expression of phosphorylated eukaryotic initiation factor 2 alpha protein (p-eif2α) and c/ebp homologous protein (chop), which are known to be involved in ros-mediated endoplasmic reticulum stress (er-stress) related apoptosis. |
2018-01-23 |
2023-08-13 |
human |
| M M Yurinskaya, O Yu Kochetkova, L I Shabarchina, O Yu Antonova, A V Suslikov, M B Evgen'ev, M G Vinokuro. Encapsulated Hsp70 decreases endotoxin-induced production of ROS and TNFα in human phagocytes. Cell stress & chaperones. vol 22. issue 1. 2018-01-17. PMID:27783274. |
encapsulated recombinant hsp70 was studied in terms of its effects on neutrophil apoptosis, the production of reactive oxygen species, and the secretion of tumor necrosis factor alpha by promonocytic thp-1 cells. |
2018-01-17 |
2023-08-13 |
human |
| Lubica Horvathova, Alexandra Padova, Andrej Tillinger, Jana Osacka, Jozef Bizik, Boris Mrave. Sympathectomy reduces tumor weight and affects expression of tumor-related genes in melanoma tissue in the mouse. Stress (Amsterdam, Netherlands). vol 19. issue 5. 2018-01-09. PMID:27416924. |
in tumor tissue from sympathectomized mice, we found significantly increased gene expression (measured by real-time pcr), relative to veh-injected controls, of tyrosine hydroxylase, neuropeptide y and glucocorticoid receptor (all p < 0.05), and alpha1, beta1 and beta3 adrenergic receptors (all p < 0.025), and factors related to apoptosis (bcl-2 and caspase-3; p < 0.05) and hypoxia (hypoxia inducible factor 1 alpha) (p = 0.005). |
2018-01-09 |
2023-08-13 |
mouse |
| El-Sayed M El-Sayed, Ahmed M Mansour, Waleed S El-Saw. Alpha lipoic acid prevents doxorubicin-induced nephrotoxicity by mitigation of oxidative stress, inflammation, and apoptosis in rats. Journal of biochemical and molecular toxicology. vol 31. issue 9. 2018-01-02. PMID:28598563. |
alpha lipoic acid prevents doxorubicin-induced nephrotoxicity by mitigation of oxidative stress, inflammation, and apoptosis in rats. |
2018-01-02 |
2023-08-13 |
rat |
| An Hue Vy Tran, Se Hee Han, Joon Kim, Francesca Grasso, In San Kim, Ye Sun Ha. MutY DNA Glycosylase Protects Cells From Tumor Necrosis Factor Alpha-Induced Necroptosis. Journal of cellular biochemistry. vol 118. issue 7. 2017-12-27. PMID:28059467. |
the association between myh and tradd is reversed during tumor necrosis factor alpha (tnf-α)- and camptothecin (cpt)-induced apoptosis, and enhanced during tnf-α-induced survival. |
2017-12-27 |
2023-08-13 |
mouse |
| Nicola Alessio, Giuseppe Esposito, Giovanni Galano, Roberto De Rosa, Pasquale Anello, Gianfranco Peluso, Maria Antonella Tabocchini, Umberto Galderis. Irradiation of Mesenchymal Stromal Cells With Low and High Doses of Alpha Particles Induces Senescence and/or Apoptosis. Journal of cellular biochemistry. vol 118. issue 9. 2017-12-21. PMID:28252222. |
irradiation of mesenchymal stromal cells with low and high doses of alpha particles induces senescence and/or apoptosis. |
2017-12-21 |
2023-08-13 |
Not clear |
| Li Zhang, Feng Ren, Xiangying Zhang, Xinxin Wang, Hongbo Shi, Li Zhou, Sujun Zheng, Yu Chen, Dexi Chen, Liying Li, Caiyan Zhao, Zhongping Dua. Peroxisome proliferator-activated receptor alpha acts as a mediator of endoplasmic reticulum stress-induced hepatocyte apoptosis in acute liver failure. Disease models & mechanisms. vol 9. issue 7. 2017-12-04. PMID:27482818. |
peroxisome proliferator-activated receptor alpha acts as a mediator of endoplasmic reticulum stress-induced hepatocyte apoptosis in acute liver failure. |
2017-12-04 |
2023-08-13 |
Not clear |
| Xuhong Chang, Fangfang Liu, Minmin Tian, Hongjun Zhao, Aijie Han, Yingbiao Su. Nickel oxide nanoparticles induce hepatocyte apoptosis via activating endoplasmic reticulum stress pathways in rats. Environmental toxicology. vol 32. issue 12. 2017-11-27. PMID:28945320. |
nano nio exposure contributed to the increased protein contents of inositol-requiring enzyme 1 (ire-1)α, p-ire-1α, x box protein-1s, pancreatic er kinase (perk), p-perk, eukaryotic initiation factor-2 alpha (eif-2α), p-eif-2α, caspase-12, -9, and -3, implicating that nano nio can activate the pathways of er stress-mediated apoptosis. |
2017-11-27 |
2023-08-13 |
rat |
| Yu-Chao Hsu, Hung-Jen Wang, Yao-Chi Chuan. Intraprostatic Botulinum Neurotoxin Type A Injection for Benign Prostatic Hyperplasia-A Spotlight in Reality. Toxins. vol 8. issue 5. 2017-11-03. PMID:27128942. |
bont-a has been shown to induce prostate apoptosis, downregulation of alpha 1a receptors, and reduce contractile function of prostate in animal studies. |
2017-11-03 |
2023-08-13 |
human |
| M Sapmaz-Metin, Y Topcu-Tarladacalisir, I Kurt-Omurlu, B Karaoz Weller, S Unsal-Ata. A morphological study of uterine alterations in mice due to exposure to cadmium. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 92. issue 4. 2017-11-02. PMID:28426261. |
we assessed uterine morphometric measurements, eosinophilia, mast cell numbers, endometrial apoptosis, proliferation and estrogen receptor alpha (erα) immunoreactivity. |
2017-11-02 |
2023-08-13 |
mouse |
| Xiukun Cui, Huiyuan Liu, Jing Li, Kangwen Guo, Wenxiu Han, Yi Dong, Simin Wan, Xuance Wang, Panpan Jia, Shulian Li, Yuanfang Ma, Jun Zhang, Hongmei Mu, Yanzhong H. Heat shock factor 4 regulates lens epithelial cell homeostasis by working with lysosome and anti-apoptosis pathways. The international journal of biochemistry & cell biology. vol 79. 2017-10-31. PMID:27586257. |
hsf4 and alpha b-crystallin can selectively protect lens epithelial cells from cisplatin and h2o2 induced apoptosis by stabilizing mitochondrial membrane potential (Δy |
2017-10-31 |
2023-08-13 |
mouse |
| Rui Hou, Yanjun Xu, Qijie Lu, Yang Zhang, Bing H. Effect of low-frequency low-intensity ultrasound with microbubbles on prostate cancer hypoxia. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 10. 2017-10-17. PMID:28974155. |
it is well established that prostate cancer is exposed to fluctuating oxygen tensions and both acute and chronic hypoxia exist, and these conditions can upregulate angiogenesis-associated proteins such as hypoxia-inducible factor 1 alpha and vascular endothelial growth factor a. low-frequency low-intensity ultrasound with microbubbles can induce obvious microvessel damage in tumors, cause cell necrosis or apoptosis. |
2017-10-17 |
2023-08-13 |
Not clear |
| Rui Hou, Yanjun Xu, Qijie Lu, Yang Zhang, Bing H. Effect of low-frequency low-intensity ultrasound with microbubbles on prostate cancer hypoxia. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 10. 2017-10-17. PMID:28974155. |
therefore, we investigated the impact of different low-frequency low-intensity ultrasound with microbubbles radiation times on prostate tumors, observed the change in the hypoxia-inducible factor 1 alpha and vascular endothelial growth factor a protein levels, as well as cell proliferation, apoptosis, and tumor volume. |
2017-10-17 |
2023-08-13 |
Not clear |
| Rui Hou, Yanjun Xu, Qijie Lu, Yang Zhang, Bing H. Effect of low-frequency low-intensity ultrasound with microbubbles on prostate cancer hypoxia. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 39. issue 10. 2017-10-17. PMID:28974155. |
the results indicated that as the radiation was repeated four times on each treatment day, the effects of interruption were durable, the cell proliferation was inhibited, and apoptosis was promoted, and the hypoxia-inducible factor 1 alpha and vascular endothelial growth factor a expression levels were lower in the treatment group than in the control group. |
2017-10-17 |
2023-08-13 |
Not clear |
| Jianfeng Han, Wei Wan. Effects of tanshinol on markers of bone turnover in ovariectomized rats and osteoblast cultures. PloS one. vol 12. issue 7. 2017-10-13. PMID:28746340. |
mc3t3-e1 cells were pretreated with 0-400 μg/ml tanshinol, and then cell viability, apoptosis, alkaline phosphatase (alp) activity and the expressions of collagen type i alpha 1 (col1a1), runt related transcription factor 2 (runx2) and osteocalcin (ocn) were respectively detected. |
2017-10-13 |
2023-08-13 |
rat |
| Aubrey Converse, Chenan Zhang, Peter Thoma. Membrane Androgen Receptor ZIP9 Induces Croaker Ovarian Cell Apoptosis via Stimulatory G Protein Alpha Subunit and MAP Kinase Signaling. Endocrinology. vol 158. issue 9. 2017-10-02. PMID:28633436. |
membrane androgen receptor zip9 induces croaker ovarian cell apoptosis via stimulatory g protein alpha subunit and map kinase signaling. |
2017-10-02 |
2023-08-13 |
human |
| Xiao Xu, Di Lu, Runzhou Zhuang, Xuyong Wei, Haiyang Xie, Chao Wang, Yangbo Zhu, Jianguo Wang, Cheng Zhong, Xuanyu Zhang, Qiang Wei, Zenglei He, Lin Zhou, Shusen Zhen. The phospholipase A2 activity of peroxiredoxin 6 promotes cancer cell death induced by tumor necrosis factor alpha in hepatocellular carcinoma. Molecular carcinogenesis. vol 55. issue 9. 2017-09-06. PMID:26293541. |
when treated with tumor necrosis factor alpha (tnf-α), prdx6 promoted apoptosis. |
2017-09-06 |
2023-08-13 |
mouse |
| Stephanie Franz, Paul Rennert, Maria Woznik, Josephine Grützke, Amy Lüdde, Eva Maria Arriero Pais, Tim Finsterbusch, Henriette Geyer, Annette Mankertz, Nicole Friedric. Mumps Virus SH Protein Inhibits NF-κB Activation by Interacting with Tumor Necrosis Factor Receptor 1, Interleukin-1 Receptor 1, and Toll-Like Receptor 3 Complexes. Journal of virology. vol 91. issue 18. 2017-09-01. PMID:28659487. |
sh has been reported to interfere with innate immunity by inhibiting tumor necrosis factor alpha (tnf-α)-mediated apoptosis and nf-κb activation. |
2017-09-01 |
2023-08-13 |
Not clear |
| Dan Li, Jing Fu, Min Du, Haibin Zhang, Lu Li, Jin Cen, Weiyun Li, Xiaotao Chen, Yunfei Lin, Edward M Conway, Eli Pikarsky, Hongyan Wang, Guoyu Pan, Yuan Ji, Hong-Yang Wang, Lijian Hu. Hepatocellular carcinoma repression by TNFα-mediated synergistic lethal effect of mitosis defect-induced senescence and cell death sensitization. Hepatology (Baltimore, Md.). vol 64. issue 4. 2017-07-31. PMID:27177758. |
here, by genetic targeting of survivin, an inhibitor of apoptosis protein (iap) that plays dual roles in mitosis and cell survival, we identified a tumor necrosis factor alpha (tnfα)-mediated synergistic lethal effect between senescence and apoptosis sensitization in malignant hccs. |
2017-07-31 |
2023-08-13 |
Not clear |
| Zhengguang Wang, Fangyuan Xiong, Xiaoshan Wang, Yijun Qi, Haoyuan Yu, Yong Zhu, Huaqing Zh. Nuclear receptor retinoid-related orphan receptor alpha promotes apoptosis but is reduced in human gastric cancer. Oncotarget. vol 8. issue 7. 2017-07-31. PMID:28052040. |
nuclear receptor retinoid-related orphan receptor alpha promotes apoptosis but is reduced in human gastric cancer. |
2017-07-31 |
2023-08-13 |
human |