| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xingzhen Lao, Bin Li, Meng Liu, Chen Shen, Tingting Yu, Xiangdong Gao, Heng Zhen. A modified thymosin alpha 1 inhibits the growth of breast cancer both in vitro and in vivo: suppressment of cell proliferation, inducible cell apoptosis and enhancement of targeted anticancer effects. Apoptosis : an international journal on programmed cell death. vol 20. issue 10. 2016-06-21. PMID:26283169. |
a modified thymosin alpha 1 inhibits the growth of breast cancer both in vitro and in vivo: suppressment of cell proliferation, inducible cell apoptosis and enhancement of targeted anticancer effects. |
2016-06-21 |
2023-08-13 |
mouse |
| Alessandro Cinti, Marco De Giorgi, Elisa Chisci, Claudia Arena, Gloria Galimberti, Laura Farina, Cristina Bugarin, Ilaria Rivolta, Giuseppe Gaipa, Ryszard Tom Smolenski, Maria Grazia Cerrito, Marialuisa Lavitrano, Roberto Giovannon. Simultaneous Overexpression of Functional Human HO-1, E5NT and ENTPD1 Protects Murine Fibroblasts against TNF-α-Induced Injury In Vitro. PloS one. vol 10. issue 10. 2016-06-21. PMID:26513260. |
we produced an f2a system-based multicistronic construct to express three human proteins in nih3t3 cells exposed to an inflammatory stimulus represented by tumor necrosis factor alpha (tnf-α), a pro-inflammatory cytokine which plays an important role during inflammation, cell proliferation, differentiation and apoptosis and in the inflammatory response during ischemia/reperfusion injury in several organ transplantation settings. |
2016-06-21 |
2023-08-13 |
human |
| Takeshi Kaizuka, Noboru Mizushim. Atg13 Is Essential for Autophagy and Cardiac Development in Mice. Molecular and cellular biology. vol 36. issue 4. 2016-06-21. PMID:26644405. |
in addition, sensitivity to tumor necrosis factor alpha (tnf-α)-induced apoptosis is enhanced by deletion of atg13 or fip200, but not by other atg proteins, as well as by simultaneous deletion of ulk1 and ulk2. |
2016-06-21 |
2023-08-13 |
mouse |
| Seung Hyeok Han, Laura Malaga-Dieguez, Frank Chinga, Hyun Mi Kang, Jianling Tao, Kimberly Reidy, Katalin Suszta. Deletion of Lkb1 in Renal Tubular Epithelial Cells Leads to CKD by Altering Metabolism. Journal of the American Society of Nephrology : JASN. vol 27. issue 2. 2016-06-07. PMID:26054542. |
treatment of lkb1-deficient cells with an amp-activated protein kinase (ampk) agonist (a769662) or a peroxisome proliferative activated receptor alpha agonist (fenofibrate) restored the fatty oxidation defect and reduced apoptosis. |
2016-06-07 |
2023-08-13 |
mouse |
| Wuting Wei, Handong Wang, Yong Wu, Ke Ding, Tao Li, Zixiang Cong, Jianguo Xu, Mengliang Zhou, Litian Huang, Hui Ding, Heming W. Alpha lipoic acid inhibits neural apoptosis via a mitochondrial pathway in rats following traumatic brain injury. Neurochemistry international. vol 87. 2016-05-24. PMID:26055972. |
alpha lipoic acid inhibits neural apoptosis via a mitochondrial pathway in rats following traumatic brain injury. |
2016-05-24 |
2023-08-13 |
rat |
| Ke Shang, Junfeng Zhang, Touseef Amna, Jieun Yang, Xiangchao Cheng, Chunjie Zhang, Inho Hwan. Attenuation of cellular toxicity by calpain inhibitor induced by bacterial endotoxin: a mechanistic study using muscle precursor cells as a model system. Molecular biology reports. vol 42. issue 8. 2016-05-23. PMID:25813209. |
additionally, lps induced apoptosis in c2c12 cells were determined by mrna expression of µ-calpain, caspase-3 and tumor necrosis factor alpha (tnf-α) and were quantified by qrt-pcr. |
2016-05-23 |
2023-08-13 |
mouse |
| Huixiang Ju, Yubao Cui, Zhiqiang Chen, Qinping Fu, Mingzhong Sun, Ying Zho. Effects of combined delivery of extremely low frequency electromagnetic field and magnetic Fe3O4 nanoparticles on hepatic cell lines. American journal of translational research. vol 8. issue 4. 2016-05-17. PMID:27186307. |
flow cytometry for anti-afp (alpha fetal protein) antibody, which coated the mnps, indicated that the combined treatment induced bel-7402 and hepg2 hepatoma cells lines into early apoptosis, without significant effects on healthy hepatic cells. |
2016-05-17 |
2023-08-13 |
Not clear |
| Cemil Bilir, Huseyin Engin, Murat Can, Yasemin Bakkal Temi, Derya Demirta. The prognostic role of inflammation and hormones in patients with metastatic cancer with cachexia. Medical oncology (Northwood, London, England). vol 32. issue 3. 2016-04-25. PMID:25638467. |
serum total testosterone, free testosterone, interleukin 1 (il) alpha and beta, il6, tumor necrosis factor (tnf) alpha, orexin, galanin, neuropeptide y, tumor necrosis factor-like weak inducer of apoptosis and tumor necrosis factor receptor-associated factor 6, and c-reactive protein (crp) levels were investigated. |
2016-04-25 |
2023-08-13 |
Not clear |
| Watcharin Loilome, Sirinun Juntana, Chadamas Pinitsoontorn, Nisana Namwat, Wichittra Tassaneeyakul, Puangrat Yongvani. Suppression of PRKAR1A expression enhances anti-proliferative and apoptotic effects of protein kinase inhibitors and chemotherapeutic drugs on cholangiocarcinoma cells. Asian Pacific journal of cancer prevention : APJCP. vol 13 Suppl. 2016-04-22. PMID:23480756. |
suppression of protein kinase a regulatory subunit 1 alpha (prkar1a) has been proven to inhibit cholangiocarcinoma (cca) cell growth and enhance apoptosis. |
2016-04-22 |
2023-08-12 |
Not clear |
| Elisabeth Holen, Juyun He, Marit Espe, Liqiou Chen, Pedro Arauj. Combining eicosapentaenoic acid, decosahexaenoic acid and arachidonic acid, using a fully crossed design, affect gene expression and eicosanoid secretion in salmon head kidney cells in vitro. Fish & shellfish immunology. vol 45. issue 2. 2016-04-07. PMID:26003739. |
the combined effect of aa + epa resulted in up-regulation of eicosanoid pathway genes and the pro-inflammatory cytokine, tumor necrosis factor alpha (tnf-α), bclx (an inducer of apoptosis) and fatty acid translocase (cd36) as well as increased cell secretion of pge2 into the media. |
2016-04-07 |
2023-08-13 |
Not clear |
| Mona Abdel Hamid, Leqaa Moemen, Hany Labib, Hazem Helmy, Tarek Elsergan. Risk of open angle glaucoma due to tumor necrosis factor alpha gene polymorphisms. Electronic physician. vol 8. issue 2. 2016-04-07. PMID:27054008. |
axonal degeneration and retinal ganglion cell apoptosis in glaucoma is associated with tumor necrosis factor alpha (tnf-α), which is an important pro-inflammatory cytokine. |
2016-04-07 |
2023-08-13 |
Not clear |
| Teresa Riegler, Marzieh Nejabat, Johannes Eichner, Melanie Stiebellehner, Sandra Subosits, Martin Bilban, Andreas Zell, Wolfgang W Huber, Rolf Schulte-Hermann, Bettina Grasl-Kraup. Proinflammatory mesenchymal effects of the non-genotoxic hepatocarcinogen phenobarbital: a novel mechanism of antiapoptosis and tumor promotion. Carcinogenesis. vol 36. issue 12. 2016-03-24. PMID:26378027. |
pb treatment in vivo or in vitro elevated the production and release of tumor necrosis factor alpha from mc, which was identified as mainly responsible for the inhibition of apoptosis in hc. |
2016-03-24 |
2023-08-13 |
human |
| Kathleen Boesze-Battaglia, Lisa P Walker, Ali Zekavat, Mensur Dlakić, Monika Damek Scuron, Patrik Nygren, Bruce J Shenke. The Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Active Subunit CdtB Contains a Cholesterol Recognition Sequence Required for Toxin Binding and Subunit Internalization. Infection and immunity. vol 83. issue 10. 2016-02-18. PMID:26216427. |
a concomitant reduction in cdt-induced toxicity was also noted, indicated by reduced cell cycle arrest and apoptosis in jurkat cells and a reduction in the proinflammatory response in macrophages (interleukin 1β [il-1β] and tumor necrosis factor alpha [tnf-α] release). |
2016-02-18 |
2023-08-13 |
human |
| Chrysoula-Evangelia Karachaliou, Christos Liolios, Charalampos Triantis, Christos Zikos, Pinelopi Samara, Ourania E Tsitsilonis, Hubert Kalbacher, Wolfgang Voelter, Minas Papadopoulos, Ioannis Pirmettis, Evangelia Livanio. Specific in vitro binding of a new (99m)Tc-radiolabeled derivative of the C-terminal decapeptide of prothymosin alpha on human neutrophils. International journal of pharmaceutics. vol 486. issue 1-2. 2016-02-04. PMID:25796124. |
prothymosin alpha (protα) is a conserved mammalian polypeptide with intracellular functions associated with cell proliferation and apoptosis and an extracellular role associated with immunopotentiation. |
2016-02-04 |
2023-08-13 |
human |
| Chih-Hsiang Hsu, Ching-Lung Lin, Sheue-Er Wang, Shuenn-Jyi Sheu, Chiang-Ting Chien, Chung-Hsin W. Oral treatment with herbal formula B401 alleviates penile toxicity in aging mice with manganism. Clinical interventions in aging. vol 10. 2016-02-04. PMID:26064043. |
nitric oxide (no) production, levels of neuronal nitric oxide synthase (nnos) and endothelial nitric oxide synthase (enos), expression levels of factors governing angiogenesis (vascular endothelial growth factor), oxidative stress (catalase, superoxide dismutase 2,4-hydroxynonenal), inflammation (tumor necrosis factor alpha), apoptosis (b-cell lymphoma 2 [bcl-2], bcl-2-associated x protein [bax], cleaved poly(adenosine diphosphate-ribose) polymerase [c-parp], cytochrome c, caspase-12, and caspase-3) were evaluated in penile corpus cavernosum of the mice. |
2016-02-04 |
2023-08-13 |
mouse |
| Richard W Smith, Phil Cash, David W Hogg, Leslie T Buc. Proteomic changes in the brain of the western painted turtle (Chrysemys picta bellii) during exposure to anoxia. Proteomics. vol 15. issue 9. 2016-01-19. PMID:25583675. |
in terms of neural protection programed cell death 6 interacting protein (pdcd6ip; a protein associated with apoptosis), dihydropyrimidinase-like protein, t-complex protein, and guanine nucleotide protein g(o) subunit alpha (go alpha; proteins associated with neural degradation and impaired cognitive function) also declined. |
2016-01-19 |
2023-08-13 |
Not clear |
| Jia-Yi Wei, Wan-Ming Li, Lin-Lin Zhou, Qiu-Nan Lu, Wei H. Melatonin induces apoptosis of colorectal cancer cells through HDAC4 nuclear import mediated by CaMKII inactivation. Journal of pineal research. vol 58. issue 4. 2016-01-11. PMID:25752481. |
moreover, constitutively active ca(2+) /calmodulin-dependent protein kinase ii alpha (camkiiα) abrogated the melatonin-induced hdac4 nuclear import and apoptosis of lovo cells. |
2016-01-11 |
2023-08-13 |
Not clear |
| Yongjia Feng, Yu-Hwai Tsai, Weidong Xiao, Matthew W Ralls, Alex Stoeck, Carole L Wilson, Elaine W Raines, Daniel H Teitelbaum, Peter J Dempse. Loss of ADAM17-Mediated Tumor Necrosis Factor Alpha Signaling in Intestinal Cells Attenuates Mucosal Atrophy in a Mouse Model of Parenteral Nutrition. Molecular and cellular biology. vol 35. issue 21. 2016-01-11. PMID:26283731. |
using a mouse tpn model, removing enteral nutrition leads to decreased crypt proliferation, increased intestinal epithelial cell (iec) apoptosis and increased mucosal tumor necrosis factor alpha (tnf-α) expression that ultimately produces mucosal atrophy. |
2016-01-11 |
2023-08-13 |
mouse |
| Yan Guo, Hui Chang, Jing Li, Xin-yuan Xu, Lan Shen, Zhi-bin Yu, Wen-chao Li. Thymosin alpha 1 suppresses proliferation and induces apoptosis in breast cancer cells through PTEN-mediated inhibition of PI3K/Akt/mTOR signaling pathway. Apoptosis : an international journal on programmed cell death. vol 20. issue 8. 2016-01-04. PMID:26002438. |
thymosin alpha 1 suppresses proliferation and induces apoptosis in breast cancer cells through pten-mediated inhibition of pi3k/akt/mtor signaling pathway. |
2016-01-04 |
2023-08-13 |
human |
| Yan Guo, Hui Chang, Jing Li, Xin-yuan Xu, Lan Shen, Zhi-bin Yu, Wen-chao Li. Thymosin alpha 1 suppresses proliferation and induces apoptosis in breast cancer cells through PTEN-mediated inhibition of PI3K/Akt/mTOR signaling pathway. Apoptosis : an international journal on programmed cell death. vol 20. issue 8. 2016-01-04. PMID:26002438. |
thymosin alpha 1 (tα1), an immunoactive peptide, has been shown to inhibit cell proliferation and induce apoptosis in human leukemia, non-small cell lung cancer, melanoma, and other human cancers. |
2016-01-04 |
2023-08-13 |
human |