Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Jorge U Carmona, Diana L Ríos, Catalina López, María E Álvarez, Jorge E Pérez, Mabel E Bohórque. In vitro effects of platelet-rich gel supernatants on histology and chondrocyte apoptosis scores, hyaluronan release and gene expression of equine cartilage explants challenged with lipopolysaccharide. BMC veterinary research. vol 12. issue 1. 2017-01-09. PMID:27369779. |
the aims were to study the influence of leukocyte- and platelet-rich gel (l-prg) and pure platelet-rich gel (p-prg) supernatants on the histological changes of cartilage, the degree of chondrocyte apoptosis, the production of hyaluronan (ha) and the gene expression of nuclear factor kappa beta (nfkβ), matrix metalloproteinase 13 (mmp-13), a disintegrin and metalloproteinase with thrombospondin motifs 4 (adamts-4), collagen type i alpha 1 (col1a1), collagen type ii alpha 1 (col2a1) and cartilage oligomeric matrix protein (comp) in normal cartilage explants (ces) challenged with lipopolysaccharide (lps). |
2017-01-09 |
2023-08-13 |
Not clear |
Dexiu Chen, Junshan Liu, Lu Lu, Yanfeng Huang, Yanjing Wang, Mingqing Wang, Yangyang Liu, Dandan Xie, Jiebing Chen, Jianxin Diao, Lianbo Wei, Ming Wan. Emodin attenuates TNF-α-induced apoptosis and autophagy in mouse C2C12 myoblasts though the phosphorylation of Akt. International immunopharmacology. vol 34. 2016-12-30. PMID:26943728. |
in this study, we investigated the protective effects and the underlying mechanisms by which emodin acts on tumor necrosis factor alpha (tnf-α)-induced apoptosis and autophagy in mouse c2c12 myoblasts. |
2016-12-30 |
2023-08-13 |
mouse |
Bruna Vasconcelos Oliveira, Paulo Goberlânio Barros Silva, Jacqueline de Santiago Nojosa, Luiz André Cavalcante Brizeno, Jamile Magalhães Ferreira, Fabrício Bitú Sousa, Mário Rogério Lima Mota, Ana Paula Negreiros Nunes Alve. TNF-alpha expression, evaluation of collagen, and TUNEL of Matricaria recutita L. extract and triamcinolone on oral ulcer in diabetic rats. Journal of applied oral science : revista FOB. vol 24. issue 3. 2016-12-22. PMID:27383710. |
to evaluate the influence of tumor necrosis factor alpha (tnf-α) and apoptosis in rats with dm treated with chamomile extract or triamcinolone. |
2016-12-22 |
2023-08-13 |
rat |
Jin Zhang, Gongxiong Wu, Haibin Da. The matricellular protein CCN1 regulates TNF-α induced vascular endothelial cell apoptosis. Cell biology international. vol 40. issue 1. 2016-12-13. PMID:25820828. |
during the development of atherosclerosis, vascular endothelial cell (ec) apoptosis induced by the adipokine tumor necrosis factor alpha (tnf-α), is an early event in the plaque formation. |
2016-12-13 |
2023-08-13 |
Not clear |
Hacer Muratoglu, Remziye Nalcacioglu, Basil M Arif, Zihni Demirba. Genome-wide analysis of differential mRNA expression of Amsacta moorei entomopoxvirus, mediated by the gene encoding a viral protein kinase (AMV197). Virus research. vol 215. 2016-12-13. PMID:26820433. |
furthermore, transcription of all studied cellular genes including metabolism of apoptosis (nedd2-like caspase, hemolin and elongation factor-1 alpha (ef1a) gene) was downregulated in the absence of amv197. |
2016-12-13 |
2023-08-13 |
human |
Dongsheng Nie, Dong Zhang, Jingbo Dai, Meixing Zhang, Xianglong Zhao, Wangjie Xu, Zhong Chen, Lianyun Wang, Zhaoxia Wang, Zhongdong Qia. Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation. Biology of reproduction. vol 94. issue 2. 2016-11-04. PMID:26607717. |
out of the 86 genes related to apoptosis, tnf (tumor necrosis factor alpha) was screened to be the most significant varied transcript, and the onto-pathway analysis indicated that the tnf apoptotic pathway was especially activated by nicotine exposure. |
2016-11-04 |
2023-08-13 |
mouse |
Xiaodu Wang, Chunyan Shao, Luyan Wang, Qunjing Li, Houhui Song, Weihuan Fan. The viral non-structural protein 1 alpha (Nsp1α) inhibits p53 apoptosis activity by increasing murine double minute 2 (mdm2) expression in porcine reproductive and respiratory syndrome virus (PRRSV) early-infected cells. Veterinary microbiology. vol 184. 2016-10-11. PMID:26854347. |
the viral non-structural protein 1 alpha (nsp1α) inhibits p53 apoptosis activity by increasing murine double minute 2 (mdm2) expression in porcine reproductive and respiratory syndrome virus (prrsv) early-infected cells. |
2016-10-11 |
2023-08-13 |
Not clear |
Jialin Duan, Ying Yin, Jia Cui, Jiajia Yan, Yanrong Zhu, Yue Guan, Guo Wei, Yan Weng, Xiaoxiao Wu, Chao Guo, Yanhua Wang, Miaomiao Xi, Aidong We. Chikusetsu Saponin IVa Ameliorates Cerebral Ischemia Reperfusion Injury in Diabetic Mice via Adiponectin-Mediated AMPK/GSK-3β Pathway In Vivo and In Vitro. Molecular neurobiology. vol 53. issue 1. 2016-10-07. PMID:25636683. |
in vitro test, chs treatment also alleviated pc12 cell injury and apoptosis, evidenced by reduced tumor necrosis factor alpha (tnf-α), malondialdehyde (mda) and caspase-3 expression, and bax/bcl-2 ratio in i/r injured cells. |
2016-10-07 |
2023-08-13 |
mouse |
Devi Kalyan Karumanchi, Nuwan Karunaratne, Laurence Lurio, James P Dillon, Elizabeth R Gaillar. Non-enzymatic glycation of α-crystallin as an in vitro model for aging, diabetes and degenerative diseases. Amino acids. vol 47. issue 12. 2016-10-05. PMID:26215735. |
alpha crystallin subunits are expressed in stress conditions and have been found to prevent apoptosis by inhibiting the activation of caspase pathway. |
2016-10-05 |
2023-08-13 |
Not clear |
Yuxuan He, Ke Wang, Xingxu Zhao, Yong Zhang, Youji Ma, Junjie H. Differential proteome association study of freeze-thaw damage in ram sperm. Cryobiology. vol 72. issue 1. 2016-09-26. PMID:26617253. |
casein kinase ii subunit alpha (csnk2a2), a serine/threonine-selective protein kinase, is associated with sperm apoptosis. |
2016-09-26 |
2023-08-13 |
Not clear |
Fukashi Yamamichi, Katsumi Shigemura, Hosny M Behnsawy, Masuo Yamashita, Toshiro Shirakawa, Masato Fujisaw. Beta-3 adrenergic receptors could be significant factors for overactive bladder-related symptoms. International journal of clinical and experimental pathology. vol 8. issue 9. 2016-09-26. PMID:26617941. |
they were investigated quantitatively by immunohistochemical (ihc) stainings for inflammatory or immune-system (interleukin (il)-6 and cyclooxygenase-2 (cox-2)), caspase-3 apoptosis markers, angiogenesis (cd-31), epithelial-mesenchymal transition (e-cadherin) and muscarinic receptor (muscarine-2 (m)-2), adrenergic receptors (ars) (alpha 1-d (α1-d) and beta-3 (β-3)). |
2016-09-26 |
2023-08-13 |
Not clear |
b' Pietro Rizza, Michele Pellegrino, Anna Caruso, Domenico Iacopetta, Maria Stefania Sinicropi, Sylvain Rault, Jean Charles Lancelot, Hussein El-Kashef, Aurelien Lesnard, Christophe Rochais, Patrick Dallemagne, Carmela Saturnino, Francesca Giordano, Stefania Catalano, Sebastiano And\\xc3\\xb. 3-(Dipropylamino)-5-hydroxybenzofuro[2,3-f]quinazolin-1(2H)-one (DPA-HBFQ-1) plays an inhibitory role on breast cancer cell growth and progression. European journal of medicinal chemistry. vol 107. 2016-09-20. PMID:26599533.' |
in particular, the latter was able to inhibit anchorage-dependent and -independent cell growth and to induce apoptosis in estrogen receptor alpha (erα)-positive and -negative breast cancer cells. |
2016-09-20 |
2023-08-13 |
human |
Hui Yang, Rui Yang, Hao Liu, Zhongqian Ren, Cuicui Wang, Da Li, Xiaoxin M. Knockdown of peroxisome proliferator-activated receptor gamma coactivator-1 alpha increased apoptosis of human endometrial cancer HEC-1A cells. OncoTargets and therapy. vol 9. 2016-09-07. PMID:27601924. |
knockdown of peroxisome proliferator-activated receptor gamma coactivator-1 alpha increased apoptosis of human endometrial cancer hec-1a cells. |
2016-09-07 |
2023-08-13 |
human |
Thangavelu Soundara Rajan, Gina Rosalinda De Nicola, Renato Iori, Patrick Rollin, Placido Bramanti, Emanuela Mazzo. Anticancer activity of glucomoringin isothiocyanate in human malignant astrocytoma cells. Fitoterapia. vol 110. 2016-09-06. PMID:26882972. |
in addition, oxidative stress related nrf2 transcription factor and its upstream regulator ck2 alpha expressions were modulated at higher doses, which indicated the involvement of oxidative stress-mediated apoptosis induced by moringin. |
2016-09-06 |
2023-08-13 |
human |
Yojiro Kotake, Kyoko Kitagawa, Tatsuya Ohhata, Satoshi Sakai, Chiharu Uchida, Hiroyuki Niida, Madoka Naemura, Masatoshi Kitagaw. Long Non-coding RNA, PANDA, Contributes to the Stabilization of p53 Tumor Suppressor Protein. Anticancer research. vol 36. issue 4. 2016-08-30. PMID:27069137. |
p21-associated noncoding rna dna damage-activated (panda) is induced in response to dna damage and represses apoptosis by inhibiting the function of nuclear transcription factor y subunit alpha (nf-ya) transcription factor. |
2016-08-30 |
2023-08-13 |
Not clear |
Ning Liu, Ke Wei, Yu Xun, Xiaoxu Yang, Shiquan Gan, Hui Xiao, Ye Xiao, Feng Yan, Guie Xie, Tingting Wang, Yinke Yang, Jian Zhang, Xiang Hu, Shuanglin Xian. Transcription factor cyclic adenosine monophosphate responsive element binding protein negatively regulates tumor necrosis factor alpha-induced protein 1 expression. Molecular medicine reports. vol 12. issue 5. 2016-08-15. PMID:26398148. |
tumor necrosis factor alpha (tnfα)-induced protein 1 (tnfaip1) was originally identified as a protein involved in dna replication, dna damage repair, apoptosis and the progression of certain diseases, such as alzheimer's disease. |
2016-08-15 |
2023-08-13 |
human |
Hyeon Jeong Lee, Eun Jig Lee, MiRan Se. Galpha12 Protects Vascular Endothelial Cells from Serum Withdrawal-Induced Apoptosis through Regulation of miR-155. Yonsei medical journal. vol 57. issue 1. 2016-08-15. PMID:26632408. |
heterotrimeric gtp-binding proteins (g proteins), including the alpha 12 subunit of g protein (gα12), have been found to modulate cellular proliferation, differentiation, and apoptosis of numerous cell types. |
2016-08-15 |
2023-08-13 |
human |
Julia Hüttmann, Eva Krause, Tim Schommartz, Wolfram Brun. Functional Comparison of Molluscum Contagiosum Virus vFLIP MC159 with Murine Cytomegalovirus M36/vICA and M45/vIRA Proteins. Journal of virology. vol 90. issue 6. 2016-07-22. PMID:26719271. |
when expressed by mcmv, mc159 blocked tumor necrosis factor alpha (tnf-α)-induced apoptosis of infected cells and partially restored mcmv replication in macrophages. |
2016-07-22 |
2023-08-13 |
mouse |
Hee-Sun Moon, Boyun Kim, HyeRan Gwak, Dong Hoon Suh, Yong Sang Son. Autophagy and protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic initiation factor 2 alpha kinase (eIF2α) pathway protect ovarian cancer cells from metformin-induced apoptosis. Molecular carcinogenesis. vol 55. issue 4. 2016-07-20. PMID:25663310. |
autophagy and protein kinase rna-like endoplasmic reticulum kinase (perk)/eukaryotic initiation factor 2 alpha kinase (eif2α) pathway protect ovarian cancer cells from metformin-induced apoptosis. |
2016-07-20 |
2023-08-13 |
Not clear |
R Rivabene, E Straface, A M Giammarioli, G Rainaldi, W Malorn. Combined effect of 3-aminobenzamide and N-acetylcysteine on HIV replication in chronically infected U937 cells. Redox report : communications in free radical research. vol 3. issue 3. 2016-07-14. PMID:27406960. |
the present investigation was designed to study the role of the nuclear enzyme poly-(adp-ribose)-polymerase (parp) when hiv- infected cells are treated with tumour necrosis factor alpha (tnfα), a cytokine capable of inducing both apoptosis and intracellular oxygen free radical production. |
2016-07-14 |
2023-08-13 |
Not clear |