| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao-Lan Qian, Wei Zhang, Ming-Zheng Liu, Yu-Bing Zhou, Jing-Min Zhang, Li Han, You-Mei Peng, Jin-hua Jiang, Qing-Duan Wan. Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice. European journal of pharmacology. vol 746. 2015-08-31. PMID:25460022. |
these results suggest that hippocampal inflammatory response and neuronal apoptosis may contribute to pocd, and selective alpha 2 adrenal receptor excitation play a protective role. |
2015-08-31 |
2023-08-13 |
mouse |
| Xiaojun Yu, Bo'an Zheng, Rui Cha. Lentivirus-mediated knockdown of eukaryotic translation initiation factor 3 subunit D inhibits proliferation of HCT116 colon cancer cells. Bioscience reports. vol 34. issue 6. 2015-08-24. PMID:25370813. |
signalling pathways responsible for cell growth and apoptosis have also been found altered after eif3d silencing, such as ampkα (amp-activated protein kinase alpha), bad, pras40 [proline-rich akt (pkb) substrate of 40 kda], sapk (stress-activated protein kinase)/jnk (c-jun n-terminal kinase), gsk3β and parp [poly(adp-ribose) polymerase]. |
2015-08-24 |
2023-08-13 |
human |
| Hsiao-Yue Wee, Sher-Wei Lim, Chung-Ching Chio, Ko-Chi Niu, Che-Chuan Wang, Jinn-Rung Ku. Hyperbaric oxygen effects on neuronal apoptosis associations in a traumatic brain injury rat model. The Journal of surgical research. vol 197. issue 2. 2015-08-24. PMID:25982374. |
the neuroprotective mechanisms of hyperbaric oxygen (hbo) therapy on traumatic brain injury (tbi) remain unclear, especially neuronal apoptosis associations such as the expression of tumor necrosis factor alpha (tnf-α), transforming growth-interacting factor (tgif), and tgf-β1 after tbi. |
2015-08-24 |
2023-08-13 |
rat |
| Ying Han, Wenxia Yi, Jiong Qin, Yang Zhao, Jing Zhang, Xingzhi Chan. Carbon monoxide offers neuroprotection from hippocampal cell damage induced by recurrent febrile seizures through the PERK-activated ER stress pathway. Neuroscience letters. vol 585. 2015-08-19. PMID:25434873. |
in the present study, using a rat model of recurrent febrile seizures (fss), we found an increase in plasma co, evidence of neuronal damage and apoptosis, an increase in the expression of the endoplasmic reticulum stress (ers) marker glucose-regulated protein 78 (grp78) and c/ebp homologous binding protein (chop), and an increase in phosphorylated protein kinase rna-like endoplasmic reticulum kinase (p-perk)/eukaryotic translation initiation factor 2 alpha (p-eif2α) in the hippocampus after 10 fss. |
2015-08-19 |
2023-08-13 |
rat |
| Gisele A D Lopes, William Y C Fan, Heloisa Ciol, Lucas T Bidinotto, Maria A M Rodrigues, Luís F Barbisa. Maternal western style diet increases susceptibility to chemically-induced mammary carcinogenesis in female rats offspring. Nutrition and cancer. vol 66. issue 8. 2015-08-05. PMID:25333700. |
immunohistochemical analysis for cell proliferation (pcna), apoptosis (cleaved caspase-3) and estrogen receptor alpha (er-α) was performed in mammary terminal end buds (tebs) at pnd 21, and pcna, er-α, and p63 analysis in mammary tumors at pnd 110. |
2015-08-05 |
2023-08-13 |
rat |
| Jun Guo, Dong Zheng, Wen-feng Li, Hai-rui Li, Ai-dong Zhang, Zi-cheng L. Insulin-like growth factor 1 treatment of MSCs attenuates inflammation and cardiac dysfunction following MI. Inflammation. vol 37. issue 6. 2015-07-20. PMID:24942913. |
in this study, we demonstrated that igf-1-treated mscs' transplantation attenuate cardiac dysfunction, increase the survival of engrafted cells in the ischemic heart, decrease myocardium cells apoptosis, and inhibit protein production and gene expression of inflammation cytokines tumor necrosis factor alpha (tnf-α), interleukin (il)-1β, and il-6. |
2015-07-20 |
2023-08-13 |
Not clear |
| Zhiqiang Zhang, Wencheng Lin, Xiaoqi Li, Hong Cao, Yongqiang Wang, Shijun J Zhen. Critical role of eukaryotic elongation factor 1 alpha 1 (EEF1A1) in avian reovirus sigma-C-induced apoptosis and inhibition of viral growth. Archives of virology. vol 160. issue 6. 2015-07-20. PMID:25854689. |
critical role of eukaryotic elongation factor 1 alpha 1 (eef1a1) in avian reovirus sigma-c-induced apoptosis and inhibition of viral growth. |
2015-07-20 |
2023-08-13 |
Not clear |
| Carlo Cenciarelli, Hany E S Marei, Manuela Zonfrillo, Pasquale Pierimarchi, Emanuela Paldino, Patrizia Casalbore, Armando Felsani, Angelo Luigi Vescovi, Giulio Maira, Annunziato Mangiol. PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment. Molecular cancer. vol 13. 2015-07-13. PMID:25380967. |
pdgf receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-notch and anti-egfr treatment. |
2015-07-13 |
2023-08-13 |
Not clear |
| Bo Yu, Lili Wen, Bing Xiao, Fang Han, Yuxiu Sh. Single Prolonged Stress induces ATF6 alpha-dependent Endoplasmic reticulum stress and the apoptotic process in medial Frontal Cortex neurons. BMC neuroscience. vol 15. 2015-07-08. PMID:25331812. |
the aim of this study was to investigate whether endoplasmic reticulum-related pathway is involved in single-prolonged stress (sps) induced apoptosis in the mpfc of ptsd rats by examining the expression levels of atf6 alpha (atf6α), two important downstream molecular chaperones of atf6α in the er stress: glucose-regulated protein (grp) 78 and erp57, and apoptotic factors caspase 12, caspase 9, and caspase 3. |
2015-07-08 |
2023-08-13 |
rat |
| Samia E Etewa, Naglaa F Abd El-Aal, Sara A Abdel-Rahman, Eman H Abd El Bary, Mahmoud A El-Shafe. Studies on the role of tumor necrosis factor- alpha (TNF-α) in hepatocytes induced apoptosis in vaccinated, Schistosoma mansoni-challenged mice. Journal of the Egyptian Society of Parasitology. vol 45. issue 1. 2015-07-02. PMID:26012218. |
studies on the role of tumor necrosis factor- alpha (tnf-α) in hepatocytes induced apoptosis in vaccinated, schistosoma mansoni-challenged mice. |
2015-07-02 |
2023-08-13 |
mouse |
| Seyedeh Nazanin Seyed Saadat, Fahimeh Mohammadghasemi, Sina Khajeh Jahromi, Mohammad Amin Homafar, Mostafa Haghir. Melatonin protects uterus and oviduct exposed to nicotine in mice. Interdisciplinary toxicology. vol 7. issue 1. 2015-06-03. PMID:26038675. |
immunohistochemistry was recruited for studying apoptosis and for detection of estrogen receptor (er) alpha in luminal epithelium of the uterus and oviduct. |
2015-06-03 |
2023-08-13 |
mouse |
| Edmond E Creppy, Aboudoulatif Diallo, Serge Moukha, Christophe Eklu-Gadegbeku, Daniel Cro. Study of epigenetic properties of Poly(HexaMethylene Biguanide) hydrochloride (PHMB). International journal of environmental research and public health. vol 11. issue 8. 2015-03-31. PMID:25111876. |
phmb does not induce significant production of mitogenic cytokines such as tnf-α (tumor necrosis factor), interleukins (il-1 alpha), and the transcription factor nuclear factor kappa b (nf-κb) which can cause either apoptosis or stimulate the growth of transformed cells or tumors. |
2015-03-31 |
2023-08-13 |
mouse |
| Guojiang Jin, Yan Zhao, Shuang Sun, Hui Kan. Association between the tumor necrosis factor alpha gene -308G> A polymorphism and the risk of breast cancer: a meta-analysis. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 12. 2015-03-10. PMID:25149156. |
the multifunctional cytokine tumor necrosis factor alpha (tnf-α) plays an important role in cell proliferation, differentiation, apoptosis, lipid metabolism, and endothelial function. |
2015-03-10 |
2023-08-13 |
Not clear |
| Dongil Kim, Seulki Lim, Minjung Park, Joohee Choi, Jongchoon Kim, Hojae Han, Kyungchul Yoon, Kwonseop Kim, Jaehyang Lim, Soohyun Par. Ubiquitination-dependent CARM1 degradation facilitates Notch1-mediated podocyte apoptosis in diabetic nephropathy. Cellular signalling. vol 26. issue 9. 2015-03-03. PMID:24726896. |
here, we demonstrate that amp-activated protein kinase alpha (ampkα) and cannabinoid receptor 1 (cb1r) are regulated by carm1 and that high-glucose-induced podocyte apoptosis is mediated by a carm1-ampkα-notch1-cb1r signaling axis. |
2015-03-03 |
2023-08-13 |
rat |
| Pierre-François Cartron, Elise Petit, Grégory Bellot, Lisa Oliver, François M Vallett. Metaxins 1 and 2, two proteins of the mitochondrial protein sorting and assembly machinery, are essential for Bak activation during TNF alpha triggered apoptosis. Cellular signalling. vol 26. issue 9. 2015-03-03. PMID:24794530. |
metaxins 1 and 2, two proteins of the mitochondrial protein sorting and assembly machinery, are essential for bak activation during tnf alpha triggered apoptosis. |
2015-03-03 |
2023-08-13 |
Not clear |
| Y Cui, Z Ma, H Zhao, X Chen, Y Zhang, H Guo, Y Zhao, Z-J Che. Activation of eIF2α signaling cascade is associated with testosterone-induced cell apoptosis in INS-1 cells. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 46. issue 8. 2015-03-03. PMID:24799026. |
testosterone/ar could not only initiate cell apoptosis but also induce the activation of eukaryotic initiation factor 2 alpha (eif2α) cascades in ins-1 cells. |
2015-03-03 |
2023-08-13 |
Not clear |
| Peng Chen, Haibin Wang, Zhijian Duan, June X Zou, Hongwu Chen, Wei He, Junjian Wan. Estrogen-related receptor alpha confers methotrexate resistance via attenuation of reactive oxygen species production and P53 mediated apoptosis in osteosarcoma cells. BioMed research international. vol 2014. 2015-02-12. PMID:24967384. |
estrogen-related receptor alpha confers methotrexate resistance via attenuation of reactive oxygen species production and p53 mediated apoptosis in osteosarcoma cells. |
2015-02-12 |
2023-08-13 |
Not clear |
| Yue Yuan, Guiyong Peng, Xiufeng Kang, Yunjie Liu, Jianhua Dai, Hongbo W. Effects of lentiviral vector-mediated TRADD expression on the inhibition of hypertrophic scar formation. Experimental biology and medicine (Maywood, N.J.). vol 239. issue 12. 2015-02-10. PMID:24962175. |
the tumor necrosis factor receptor-associated death domain protein (tradd) regulates cell proliferation and apoptosis via tumor necrosis factor alpha (tnf-α)-mediated signaling pathways. |
2015-02-10 |
2023-08-13 |
human |
| Baofeng Yang, Kaiwen He, Fangfang Zheng, Lin Wan, Xiangru Yu, Xuelian Wang, Dan Zhao, Yunlong Bai, Wenfeng Chu, Yan Sun, Yanjie L. Over-expression of hypoxia-inducible factor-1 alpha in vitro protects the cardiac fibroblasts from hypoxia-induced apoptosis. Journal of cardiovascular medicine (Hagerstown, Md.). vol 15. issue 7. 2015-01-27. PMID:24583668. |
over-expression of hypoxia-inducible factor-1 alpha in vitro protects the cardiac fibroblasts from hypoxia-induced apoptosis. |
2015-01-27 |
2023-08-12 |
rat |
| S A H de Poot, K W Lai, L van der Wal, K Plasman, P Van Damme, A C Porter, K Gevaert, N Bovensche. Granzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis. Cell death and differentiation. vol 21. issue 3. 2015-01-15. PMID:24185622. |
granzyme m targets topoisomerase ii alpha to trigger cell cycle arrest and caspase-dependent apoptosis. |
2015-01-15 |
2023-08-12 |
human |