Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Amir Kalafi, Farideh Jowka. Evaluation of the Efficacy of Topical Tetracycline in Enhancing the Effect of Narrow Band UVB against Vitiligo: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial. ISRN dermatology. vol 2014. 2014-03-25. PMID:24665368. |
increased levels of tumor necrosis factor alpha and interleukin-1 in the epidermis of lesions may play a role in keratinocyte apoptosis and less production of melanogenic cytokines. |
2014-03-25 |
2023-08-12 |
Not clear |
D S Meyer, N Aceto, N Sausgruber, H Brinkhaus, U Müller, C J Pallen, M Bentires-Al. Tyrosine phosphatase PTPα contributes to HER2-evoked breast tumor initiation and maintenance. Oncogene. vol 33. issue 3. 2014-03-14. PMID:23318421. |
protein tyrosine phosphatase alpha (ptpα/ptpra) was shown previously to be overexpressed in human primary breast cancers, and to suppress apoptosis in estrogen receptor-negative breast cancer cells in vitro. |
2014-03-14 |
2023-08-12 |
mouse |
A I Raya, J C Gomez-Villamandos, P J Sánchez-Cordón, M J Bautist. Virus distribution and role of thymic macrophages during experimental infection with noncytopathogenic bovine viral diarrhea virus type 1. Veterinary pathology. vol 49. issue 5. 2014-02-19. PMID:21768605. |
furthermore, the results imply that, in contrast to the situation with classical swine fever virus, the lymphocyte apoptosis resulting from bovine viral diarrhea virus infection is not mediated by tnf-α or interleukin-1 alpha (il-1α) production by virus-infected macrophages. |
2014-02-19 |
2023-08-12 |
cattle |
Musa Mulongo, Tracy Prysliak, Erin Scruten, Scott Napper, Jose Perez-Casa. In vitro infection of bovine monocytes with Mycoplasma bovis delays apoptosis and suppresses production of gamma interferon and tumor necrosis factor alpha but not interleukin-10. Infection and immunity. vol 82. issue 1. 2014-02-19. PMID:24126524. |
in vitro infection of bovine monocytes with mycoplasma bovis delays apoptosis and suppresses production of gamma interferon and tumor necrosis factor alpha but not interleukin-10. |
2014-02-19 |
2023-08-12 |
cattle |
Musa Mulongo, Tracy Prysliak, Erin Scruten, Scott Napper, Jose Perez-Casa. In vitro infection of bovine monocytes with Mycoplasma bovis delays apoptosis and suppresses production of gamma interferon and tumor necrosis factor alpha but not interleukin-10. Infection and immunity. vol 82. issue 1. 2014-02-19. PMID:24126524. |
here, we show that infection of bovine blood monocytes with m. bovis delays spontaneous or tumor necrosis factor alpha (tnf-α)/staurosporine-driven apoptosis, activates the nf-κb p65 subunit, and inhibits caspase-9 activity. |
2014-02-19 |
2023-08-12 |
cattle |
Patricia Rivera, Margarita Pérez-Martín, Francisco J Pavón, Antonia Serrano, Ana Crespillo, Manuel Cifuentes, María-Dolores López-Ávalos, Jesús M Grondona, Margarita Vida, Pedro Fernández-Llebrez, Fernando Rodríguez de Fonseca, Juan Suáre. Pharmacological administration of the isoflavone daidzein enhances cell proliferation and reduces high fat diet-induced apoptosis and gliosis in the rat hippocampus. PloS one. vol 8. issue 5. 2014-02-18. PMID:23741384. |
then, plasma levels of metabolites and metabolic hormones, cell proliferation in the subgranular zone of the dentate gyrus (sgz), and immunohistochemical markers of hippocampal cell apoptosis (caspase-3), gliosis (gfap and iba-1), food reward factor fosb and estrogen receptor alpha (erα) were analyzed. |
2014-02-18 |
2023-08-12 |
rat |
Hung Chuan Pan, Cheng Ning Yang, Yi Wen Hung, Wen Jane Lee, Hsing Ru Tien, Chin Chang Shen, Jason Sheehan, Chiang Ting Chou, Meei Ling She. Reciprocal modulation of C/EBP-α and C/EBP-β by IL-13 in activated microglia prevents neuronal death. European journal of immunology. vol 43. issue 11. 2014-02-06. PMID:23881867. |
in response to aggravation by activated microglia, il-13 can significantly enhance er stress induction, apoptosis, and death via reciprocal signaling through ccaat/enhancer-binding protein alpha (c/ebp-α) and c/ebp-beta (c/ebp-β). |
2014-02-06 |
2023-08-12 |
Not clear |
Mohammad Mahabub-Uz Zaman, Teruaki Nomura, Tsuyoshi Takagi, Tomoo Okamura, Wanzhu Jin, Toshie Shinagawa, Yasunori Tanaka, Shunsuke Ishi. Ubiquitination-deubiquitination by the TRIM27-USP7 complex regulates tumor necrosis factor alpha-induced apoptosis. Molecular and cellular biology. vol 33. issue 24. 2014-01-28. PMID:24144979. |
tumor necrosis factor alpha (tnf-α) plays a role in apoptosis and proliferation in multiple types of cells, and defects in tnf-α-induced apoptosis are associated with various autoimmune diseases. |
2014-01-28 |
2023-08-12 |
mouse |
Xiao-Yan Jiang, De-Bin Lu, You-Zhao Jiang, Li-Na Zhou, Li-Qing Cheng, Bing Che. PGC-1α prevents apoptosis in adipose-derived stem cells by reducing reactive oxygen species production in a diabetic microenvironment. Diabetes research and clinical practice. vol 100. issue 3. 2014-01-10. PMID:23618552. |
to examine whether overexpression of peroxisome proliferator activated receptor-gamma coactivator-1 alpha (pgc-1α) can prevent apoptosis in adipose-derived stem cells (ascs) by reducing reactive oxygen species (ros) production and enhancing mitochondrial function in a diabetic environment. |
2014-01-10 |
2023-08-12 |
Not clear |
Ahmad Fawzi Hussain, Mehmet Kemal Tur, Stefan Bart. An aptamer-siRNA chimera silences the eukaryotic elongation factor 2 gene and induces apoptosis in cancers expressing αvβ3 integrin. Nucleic acid therapeutics. vol 23. issue 3. 2013-12-09. PMID:23544955. |
we therefore joined an aptamer-recognizing alpha v and integrin beta 3 (αvβ3) integrin to a sirna that targets eukaryotic elongation factor 2 and achieved for the first time the targeted delivery of a sirna to tumor cells expressing αvβ3 integrin, causing the inhibition of cell proliferation and the induction of apoptosis specifically in tumor cells. |
2013-12-09 |
2023-08-12 |
Not clear |
Krithika Lingappan, Weiwu Jiang, Lihua Wang, Xanthi I Couroucli, Roberto Barrios, Bhagavatula Moorth. Sex-specific differences in hyperoxic lung injury in mice: implications for acute and chronic lung disease in humans. Toxicology and applied pharmacology. vol 272. issue 2. 2013-11-26. PMID:23792423. |
after exposure to hyperoxia, lung injury, levels of 8-iso-prostaglandin f2 alpha (8-iso-pgf 2α) (lc-ms/ms), apoptosis (tunel) and inflammatory markers (suspension bead array) were determined. |
2013-11-26 |
2023-08-12 |
mouse |
b' Tatjana Radjenovi\\xc4\\x87 Petkovi\\xc4\\x87, Tatjana Pejci\\xc4\\x87, Jelica Videnovi\\xc4\\x87-Ivanov, Tatjana Jevtovi\\xc4\\x87 Stoimenov, Irena Jankovi\\xc4\\x87, Desa Nastasijevi\\xc4\\x87 Borovac, Danijela Radojkovi\\xc4\\x8. Tumor necrosis factor alpha gene polymorphism in serbian patients with sarcoidosis. Srpski arhiv za celokupno lekarstvo. vol 141. issue 3-4. 2013-11-22. PMID:23745338.' |
tumor necrosis factor alpha (tnf-a) is a proinflammatory cytokine which plays an important role in the pathogenesis of the disease and the formation of granuloma by regulating cellular proliferation and apoptosis. |
2013-11-22 |
2023-08-12 |
Not clear |
Zahra Nasiri-Toosi, Simin Dashti-Khavidaki, Hossein Khalili, Mahboob Lessan-Pezeshk. A review of the potential protective effects of pentoxifylline against drug-induced nephrotoxicity. European journal of clinical pharmacology. vol 69. issue 5. 2013-11-19. PMID:23179178. |
some possible pharmacologic mechanisms of pentoxifylline (ptx) that suggest it as a candidate to ameliorate aki include interaction at the level of the adenosine receptors, increase in erythrocyte deformability, stimulation of vasodilatory prostaglandins production and prevention of vascular congestion, and suppression of tumor necrosis factor alpha (tnf-α) and apoptosis. |
2013-11-19 |
2023-08-12 |
Not clear |
Lei Guo, Jiping Xu, Jin Qi, Lianfang Zhang, Jinsheng Wang, Jing Liang, Niandong Qian, Hanbing Zhou, Li Wei, Lianfu Den. MicroRNA-17-92a upregulation by estrogen leads to Bim targeting and inhibition of osteoblast apoptosis. Journal of cell science. vol 126. issue Pt 4. 2013-11-19. PMID:23264746. |
the microrna cluster mir-17-92a, a post-transcriptional regulator, was significantly reduced during dexamethasone, etoposide and tumor necrosis factor alpha (tnf-α)-induced osteoblasts apoptosis. |
2013-11-19 |
2023-08-12 |
Not clear |
Seong-Hui Eo, Hongsik Cho, Song-Ja Ki. Resveratrol Inhibits Nitric Oxide-Induced Apoptosis via the NF-Kappa B Pathway in Rabbit Articular Chondrocytes. Biomolecules & therapeutics. vol 21. issue 5. 2013-11-18. PMID:24244824. |
snp-induced degradation of i-kappa b alpha (iκb-α) was rescued by resveratrol treatment, and the sn50 peptide-mediated inhibition of nf-kappa b (nf-κb) activity potently blocked snp-induced caspase-3 activation and apoptosis. |
2013-11-18 |
2023-08-12 |
rabbit |
Pinelopi Samara, Hubert Kalbacher, Kyriaki Ioannou, Dorel L Radu, Evangelia Livaniou, Vasilis J Promponas, Wolfgang Voelter, Ourania Tsitsiloni. Development of an ELISA for the quantification of the C-terminal decapeptide prothymosin α(100-109) in sera of mice infected with bacteria. Journal of immunological methods. vol 395. issue 1-2. 2013-11-13. PMID:23831611. |
apoptosis is characterized by a series of discrete biochemical events, among which is the truncation of the nuclear polypeptide prothymosin alpha (protα) by activated caspase-3. |
2013-11-13 |
2023-08-12 |
mouse |
Juen-Haur Hwang, Chuan-Jen Hsu, Wei-Hsuan Yu, Tien-Chen Liu, Wei-Shiung Yan. Diet-induced obesity exacerbates auditory degeneration via hypoxia, inflammation, and apoptosis signaling pathways in CD/1 mice. PloS one. vol 8. issue 4. 2013-11-11. PMID:23637762. |
immunohistochemical staining showed that hypoxia-induced factor 1 (hif-1), tumor necrosis factor alpha (tnf-α), nuclear factor kappa b (nf-κb), caspase 3, poly(adp-ribose) polymerase-1, and apoptosis inducing factor were all significantly more dense in the spiral ganglion and spiral ligament at the basal turn of cochlea in the dio group. |
2013-11-11 |
2023-08-12 |
mouse |
Yun Wang, Meng Cao, Aiqin Liu, Wenyu Di, Fen Zhao, Yunjiao Tian, Jianwei Ji. Changes of inflammatory cytokines and neurotrophins emphasized their roles in hypoxic-ischemic brain damage. The International journal of neuroscience. vol 123. issue 3. 2013-10-31. PMID:23110519. |
in this article, we compared the levels of tumor necrosis factor alpha (tnf-α), intercellular adhesion molecule-1 (icam-1), interleukin 1beta (il-1β), nerve growth factor (ngf), and brain-derived neurotrophic factor (bdnf) in the progression of hibd and analyzed their correlations with apoptosis. |
2013-10-31 |
2023-08-12 |
rat |
Yun Li, Ya-Zhen Liu, Jing-Ming Shi, Song-Bai Ji. Alpha lipoic acid protects lens from H(2)O(2)-induced cataract by inhibiting apoptosis of lens epithelial cells and inducing activation of anti-oxidative enzymes. Asian Pacific journal of tropical medicine. vol 6. issue 7. 2013-10-17. PMID:23768827. |
alpha lipoic acid protects lens from h(2)o(2)-induced cataract by inhibiting apoptosis of lens epithelial cells and inducing activation of anti-oxidative enzymes. |
2013-10-17 |
2023-08-12 |
Not clear |
Alexander Brendel, Vanessa Felzen, Tobias Morawe, Dieter Manthey, Christian Beh. Differential regulation of apoptosis-associated genes by estrogen receptor alpha in human neuroblastoma cells. Restorative neurology and neuroscience. vol 31. issue 2. 2013-09-20. PMID:23271418. |
here we investigated potential targets of the er subtype alpha that may mediate neuroprotection and focused on direct modulators and downstream executors of apoptosis. |
2013-09-20 |
2023-08-12 |
human |