| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tri Wibawa, Lisa Pangemanan, Farida J Rachmawaty, Ning Rintiswati, Mustofa, Marsetyawan H N E Soesaty. Isoniazid (INH) treatment of INH-resistant Mycobacterium tuberculosis inhibits infected macrophage to produce TNF-alpha. The Southeast Asian journal of tropical medicine and public health. vol 45. issue 5. 2015-01-08. PMID:25417512. |
macrophages undergo apoptosis after infected by mycobacterium tuber- culosis (m.tb), which is regulated by tumor necrosis factor alpha (tnf-alpha) and has a direct correlation with killing of intracellular bacilli. |
2015-01-08 |
2023-08-13 |
Not clear |
| Li Wang, Xin-Mei Kang, Ying Song, Wen-Jie Ma, Hong Zhao, Qing-Yuan Zhan. [Effect of genistein combined with anastrozole on mammary tumors in ovariectomized rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 34. issue 4. 2015-01-05. PMID:24812910. |
to evaluate the inhibitory effect of genistin combined with anastrozole on the growth and apoptosis of breast tumor tissue, and to study their anti-cancer mechanism by using the model of 7,12-dimethylbenz [alpha] anthracene (dmba)-induced mammary tumors following ovariectomy in sprague-dawley (sd) rats. |
2015-01-05 |
2023-08-13 |
rat |
| Tian Xia, Hao Cheng, Yu Zh. Knockdown of hypoxia-inducible factor-1 alpha reduces proliferation, induces apoptosis and attenuates the aggressive phenotype of retinoblastoma WERI-Rb-1 cells under hypoxic conditions. Annals of clinical and laboratory science. vol 44. issue 2. 2014-12-17. PMID:24795051. |
knockdown of hypoxia-inducible factor-1 alpha reduces proliferation, induces apoptosis and attenuates the aggressive phenotype of retinoblastoma weri-rb-1 cells under hypoxic conditions. |
2014-12-17 |
2023-08-13 |
Not clear |
| Seung Yeon Park, Jung Hyun Shim, Young Sik Ch. Distinctive roles of receptor-interacting protein kinases 1 and 3 in caspase-independent cell death of L929. Cell biochemistry and function. vol 32. issue 1. 2014-10-23. PMID:23584955. |
upon tumour necrosis factor alpha (tnfα) stimulation, cells respond actively by way of cell survival, apoptosis or programmed necrosis. |
2014-10-23 |
2023-08-12 |
Not clear |
| Aracely Angulo-Molina, Julio Reyes-Leyva, Aurelio López-Malo, Jesús Hernánde. The role of alpha tocopheryl succinate (α-TOS) as a potential anticancer agent. Nutrition and cancer. vol 66. issue 2. 2014-10-15. PMID:24364743. |
alpha tocopheryl succinate (α-tos) is the most effective form of vitamin e analogues causing inhibition of proliferation and apoptosis of cancer cells. |
2014-10-15 |
2023-08-12 |
Not clear |
| Paulina Gómez-Lomelí, Alejandro Bravo-Cuellar, Georgina Hernández-Flores, Luis Felipe Jave-Suárez, Adriana Aguilar-Lemarroy, José Manuel Lerma-Díaz, Jorge Ramiro Domínguez-Rodríguez, Karina Sánchez-Reyes, Pablo Cesar Ortiz-Lazaren. Increase of IFN-γ and TNF-α production in CD107a + NK-92 cells co-cultured with cervical cancer cell lines pre-treated with the HO-1 inhibitor. Cancer cell international. vol 14. issue 1. 2014-10-10. PMID:25302050. |
natural killer (nk) cells eliminate virus-infected and tumor cells through the release of perforins and granzymes; they also produce interferon gamma (ifn-γ) and tumor necrosis factor alpha (tnf-α), which induce apoptosis in target cells. |
2014-10-10 |
2023-08-13 |
Not clear |
| Jintapat Nateewattana, Suman Dutta, Somrudee Reabroi, Rungnapha Saeeng, Sakkasem Kasemsook, Arthit Chairoungdua, Jittima Weerachayaphorn, Sopit Wongkham, Pawinee Piyachaturawa. Induction of apoptosis in cholangiocarcinoma by an andrographolide analogue is mediated through topoisomerase II alpha inhibition. European journal of pharmacology. vol 723. 2014-10-07. PMID:24360936. |
induction of apoptosis in cholangiocarcinoma by an andrographolide analogue is mediated through topoisomerase ii alpha inhibition. |
2014-10-07 |
2023-08-12 |
human |
| Harina Vin, Grace Ching, Sandra S Ojeda, Charles H Adelmann, Vida Chitsazzadeh, David W Dwyer, Haiching Ma, Karin Ehrenreiter, Manuela Baccarini, Rosamaria Ruggieri, Jonathan L Curry, Ana M Ciurea, Madeleine Duvic, Naifa L Busaidy, Nizar M Tannir, Kenneth Y Tsa. Sorafenib suppresses JNK-dependent apoptosis through inhibition of ZAK. Molecular cancer therapeutics. vol 13. issue 1. 2014-09-29. PMID:24170769. |
here, we report that sorafenib suppresses uv-induced apoptosis specifically by inhibiting c-jun-nh(2)-kinase (jnk) activation through the off-target inhibition of leucine zipper and sterile alpha motif-containing kinase (zak). |
2014-09-29 |
2023-08-12 |
Not clear |
| Xiqing Chai, Weina Kong, Lingyun Liu, Wenguo Yu, Zhenqing Zhang, Yimin Su. A viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis. Neural regeneration research. vol 9. issue 11. 2014-09-10. PMID:25206774. |
a viral vector expressing hypoxia-inducible factor 1 alpha inhibits hippocampal neuronal apoptosis. |
2014-09-10 |
2023-08-13 |
human |
| S Sengupta, I Obiorah, P Y Maximov, R Curpan, V C Jorda. Molecular mechanism of action of bisphenol and bisphenol A mediated by oestrogen receptor alpha in growth and apoptosis of breast cancer cells. British journal of pharmacology. vol 169. issue 1. 2014-09-05. PMID:23373633. |
molecular mechanism of action of bisphenol and bisphenol a mediated by oestrogen receptor alpha in growth and apoptosis of breast cancer cells. |
2014-09-05 |
2023-08-12 |
Not clear |
| Chad R Sethman, Jacek Hawige. The innate immunity adaptor SARM translocates to the nucleus to stabilize lamins and prevent DNA fragmentation in response to pro-apoptotic signaling. PloS one. vol 8. issue 7. 2014-08-21. PMID:23923041. |
sterile alpha and armadillo-motif containing protein (sarm), a highly conserved and structurally unique member of the myd88 family of toll-like receptor adaptors, plays an important role in innate immunity signaling and apoptosis. |
2014-08-21 |
2023-08-12 |
human |
| Tao Zhang, Zhichao Zheng, Yanqing Liu, Jianjun Zhang, Yan Zhao, Yong Liu, Haitao Zhu, Guohua Zhao, Jiwang Liang, Qiang Li, Huimian X. Overexpression of methionine adenosyltransferase II alpha (MAT2A) in gastric cancer and induction of cell cycle arrest and apoptosis in SGC-7901 cells by shRNA-mediated silencing of MAT2A gene. Acta histochemica. vol 115. issue 1. 2014-08-12. PMID:22542325. |
overexpression of methionine adenosyltransferase ii alpha (mat2a) in gastric cancer and induction of cell cycle arrest and apoptosis in sgc-7901 cells by shrna-mediated silencing of mat2a gene. |
2014-08-12 |
2023-08-12 |
Not clear |
| Guixiang Sun, Yanni Zhou, Hongsheng Li, Yingjia Guo, Juan Shan, Mengjuan Xia, Youping Li, Shengfu Li, Dan Long, Li Fen. Over-expression of microRNA-494 up-regulates hypoxia-inducible factor-1 alpha expression via PI3K/Akt pathway and protects against hypoxia-induced apoptosis. Journal of biomedical science. vol 20. 2014-07-09. PMID:24364919. |
over-expression of microrna-494 up-regulates hypoxia-inducible factor-1 alpha expression via pi3k/akt pathway and protects against hypoxia-induced apoptosis. |
2014-07-09 |
2023-08-12 |
Not clear |
| Elena Donadio, Laura Giusti, Veronica Seccia, Federica Ciregia, Ylenia da Valle, Iacopo Dallan, Tiziana Ventroni, Gino Giannaccini, Stefano Sellari-Franceschini, Antonio Lucacchin. New insight into benign tumours of major salivary glands by proteomic approach. PloS one. vol 8. issue 8. 2014-06-26. PMID:24205396. |
intriguingly, all warthin's tumour up-regulated proteins such as ig gamma-1 chain c region, ig kappa chain c region and ig alpha-1 chain c region and s100a9 were correlated to immunological and inflammatory diseases, while pleomorphic adenomas such as annexin a1, annexin a4, macrophage-capping protein, apolipoprotein e and alpha crystalline b chain were associated with cell death, apoptosis and tumorigenesis, showing different features of two benign tumours. |
2014-06-26 |
2023-08-12 |
Not clear |
| Kazunori Hamamura, Nancy Tanjung, Hiroki Yokot. Suppression of osteoclastogenesis through phosphorylation of eukaryotic translation initiation factor 2 alpha. Journal of bone and mineral metabolism. vol 31. issue 6. 2014-06-24. PMID:23536193. |
in response to various stresses including viral infection, nutrient deprivation, and stress to the endoplasmic reticulum, eukaryotic translation initiation factor 2 alpha (eif2α) is phosphorylated to cope with stress induced apoptosis. |
2014-06-24 |
2023-08-12 |
Not clear |
| Natik Piri, Jacky M K Kwong, Joseph Capriol. Crystallins in retinal ganglion cell survival and regeneration. Molecular neurobiology. vol 48. issue 3. 2014-06-18. PMID:23709342. |
alpha crystallins (alpha a and alpha b) share significant homology with small heat shock proteins and have chaperone-like properties, including the ability to bind and prevent the precipitation of denatured proteins and to increase cellular resistance to stress-induced apoptosis. |
2014-06-18 |
2023-08-12 |
Not clear |
| Lamia Hamdan, Zoheir Arrar, Yacoub Al Muataz, Lutfi Suleiman, Claude Négrier, Joseph Kajima Mulengi, Habib Boukerch. Alpha cyano-4-hydroxy-3-methoxycinnamic acid inhibits proliferation and induces apoptosis in human breast cancer cells. PloS one. vol 8. issue 9. 2014-06-15. PMID:24039831. |
alpha cyano-4-hydroxy-3-methoxycinnamic acid inhibits proliferation and induces apoptosis in human breast cancer cells. |
2014-06-15 |
2023-08-12 |
human |
| Tarkan Karakan, Mustafa Kerem, Mehmet Cindoruk, Doruk Engin, Murat Alper, Okan Akı. PPAR-alpha agonist treatment increases trefoil factor family-3 expression and attenuates apoptosis in the liver tissue of bile duct-ligated rats. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology. vol 24. issue 2. 2014-05-12. PMID:23934460. |
we evaluated the effect of short-term administration of fenofibrate, a peroxisome proliferators activated receptor alpha agonist, on trefoil factor family-3 expression, degree of apoptosis, generation of free radicals, and levels of proinflammatory cytokines in the liver tissue of bile duct-ligated rats. |
2014-05-12 |
2023-08-12 |
rat |
| Jisen Huai, F-Nora Vögtle, Lars Jöckel, Yunbo Li, Thomas Kiefer, Jean-Ehrland Ricci, Christoph Borne. TNFα-induced lysosomal membrane permeability is downstream of MOMP and triggered by caspase-mediated NDUFS1 cleavage and ROS formation. Journal of cell science. vol 126. issue Pt 17. 2014-04-25. PMID:23788428. |
when nf-κb activation or protein synthesis is inhibited, tumor necrosis factor alpha (tnfα) can induce apoptosis through bax- and bak-mediated mitochondrial outer membrane permeabilization (momp) leading to caspase-3 activation. |
2014-04-25 |
2023-08-12 |
Not clear |
| Andrew J M Campbell-Lloyd, Julie Mundy, Rajeev Deva, Guy Lampe, Carmel Hawley, Glen Boyle, Rayleene Griffin, Charles Thompson, Pallav Sha. Is alpha-B crystallin an independent marker for prognosis in lung cancer? Heart, lung & circulation. vol 22. issue 9. 2014-04-18. PMID:23582651. |
alpha b-crystallin (cryab) is an oncogene that increases tumour survival by promoting angiogenesis and preventing apoptosis. |
2014-04-18 |
2023-08-12 |
Not clear |