| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T W Salcedo, H B Flei. Detection of tumor necrosis factor induced nuclear damage with p-phenylenediamine. Journal of immunological methods. vol 148. issue 1-2. 1992-05-19. PMID:1373426. |
using the intercalating dye p-phenylenediamine to stain nuclei, we detected tnf alpha-induced nuclear alterations which characteristically occur during apoptosis in the tnf alpha sensitive u937 cell line. |
1992-05-19 |
2023-08-11 |
Not clear |
| G Bellomo, M Perotti, F Taddei, F Mirabelli, G Finardi, P Nicotera, S Orreniu. Tumor necrosis factor alpha induces apoptosis in mammary adenocarcinoma cells by an increase in intranuclear free Ca2+ concentration and DNA fragmentation. Cancer research. vol 52. issue 5. 1992-03-18. PMID:1737395. |
tumor necrosis factor alpha induces apoptosis in mammary adenocarcinoma cells by an increase in intranuclear free ca2+ concentration and dna fragmentation. |
1992-03-18 |
2023-08-11 |
human |
| G Bellomo, M Perotti, F Taddei, F Mirabelli, G Finardi, P Nicotera, S Orreniu. Tumor necrosis factor alpha induces apoptosis in mammary adenocarcinoma cells by an increase in intranuclear free Ca2+ concentration and DNA fragmentation. Cancer research. vol 52. issue 5. 1992-03-18. PMID:1737395. |
our findings suggest that tumor necrosis factor alpha can promote an increase in intranuclear free ca2+ which, in turn, may stimulate ca(2+)-dependent endonuclease activity, resulting in dna fragmentation and apoptosis. |
1992-03-18 |
2023-08-11 |
human |
| M J Holder, Y J Liu, T Defrance, L Flores-Romo, I C MacLennan, J Gordo. Growth factor requirements for the stimulation of germinal center B cells: evidence for an IL-2-dependent pathway of development. International immunology. vol 3. issue 12. 1992-03-12. PMID:1723294. |
germinal center (gc) b cells readily undergo apoptosis, a tendency which can be suppressed in vitro by immobilized anti-ig; mab to cd40 and soluble cd23 (in synergy with il-1 alpha) also effect rescue of gc cells from programmed cell death. |
1992-03-12 |
2023-08-11 |
Not clear |
| T Shinagawa, K Yoshioka, S Kakumu, T Wakita, T Ishikawa, Y Itoh, M Takayanag. Apoptosis in cultured rat hepatocytes: the effects of tumour necrosis factor alpha and interferon gamma. The Journal of pathology. vol 165. issue 3. 1992-02-07. PMID:1762032. |
apoptosis in cultured rat hepatocytes: the effects of tumour necrosis factor alpha and interferon gamma. |
1992-02-07 |
2023-08-11 |
rat |
| T Shinagawa, K Yoshioka, S Kakumu, T Wakita, T Ishikawa, Y Itoh, M Takayanag. Apoptosis in cultured rat hepatocytes: the effects of tumour necrosis factor alpha and interferon gamma. The Journal of pathology. vol 165. issue 3. 1992-02-07. PMID:1762032. |
tnf alpha killed cultured rat hepatocytes by increasing apoptosis, and this effect was potentiated by the addition of ifn gamma, which by itself was also weakly cytotoxic. |
1992-02-07 |
2023-08-11 |
rat |
| P Golstein, D M Ojcius, J D Youn. Cell death mechanisms and the immune system. Immunological reviews. vol 121. 1991-12-13. PMID:1937533. |
cell death is strikingly polymorphic: it can proceed via necrosis (as in complement-mediated cell death) or apoptosis, but the latter displays different patterns (in the receptor-mediated death of some thymocytes, in cell death mediated by tnf alpha or by cytotoxic t cells), perhaps reflecting different pathways of control of a common core mechanism. |
1991-12-13 |
2023-08-11 |
Not clear |
| M J Lenard. Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis. Nature. vol 353. issue 6347. 1991-12-02. PMID:1944559. |
interleukin-2 programs mouse alpha beta t lymphocytes for apoptosis. |
1991-12-02 |
2023-08-11 |
mouse |
| D M Ojcius, A Zychlinsky, L M Zheng, J D Youn. Ionophore-induced apoptosis: role of DNA fragmentation and calcium fluxes. Experimental cell research. vol 197. issue 1. 1991-11-21. PMID:1915662. |
two ionophores specific for k+, valinomycin and beauvericin, induce a type of cell death very similar to apoptosis due to tumor necrosis factor (tnf alpha). |
1991-11-21 |
2023-08-11 |
Not clear |
| K A Hogquist, M A Nett, E R Unanue, D D Chapli. Interleukin 1 is processed and released during apoptosis. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 19. 1991-10-31. PMID:1924307. |
in contrast, when cells undergo apoptosis, maturation of both il-1 alpha and il-1 beta is efficient. |
1991-10-31 |
2023-08-11 |
Not clear |
| K Fehsel, V Kolb-Bachofen, H Kol. Analysis of TNF alpha-induced DNA strand breaks at the single cell level. The American journal of pathology. vol 139. issue 2. 1991-09-06. PMID:1867316. |
treatment of l929 cells with tnf alpha initiates apoptosis and subsequent cell death. |
1991-09-06 |
2023-08-11 |
Not clear |
| S R Sambhara, R G Mille. Programmed cell death of T cells signaled by the T cell receptor and the alpha 3 domain of class I MHC. Science (New York, N.Y.). vol 252. issue 5011. 1991-07-18. PMID:1828618. |
deletion by programmed cell death (apoptosis) is triggered if a t cell that has received a signal through its t cell receptor complex also receives a signal through the alpha 3 domain of its class i major histocompatibility complex (mhc) molecule. |
1991-07-18 |
2023-08-11 |
Not clear |
| Y J Liu, J A Cairns, M J Holder, S D Abbot, K U Jansen, J Y Bonnefoy, J Gordon, I C MacLenna. Recombinant 25-kDa CD23 and interleukin 1 alpha promote the survival of germinal center B cells: evidence for bifurcation in the development of centrocytes rescued from apoptosis. European journal of immunology. vol 21. issue 5. 1991-06-28. PMID:1828027. |
recombinant 25-kda cd23 and interleukin 1 alpha promote the survival of germinal center b cells: evidence for bifurcation in the development of centrocytes rescued from apoptosis. |
1991-06-28 |
2023-08-11 |
Not clear |
| M K Newell, L J Haughn, C R Maroun, M H Juliu. Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen. Nature. vol 347. issue 6290. 1990-10-19. PMID:2144894. |
here we report that when preceded by ligation of cd4, signalling through tcr alpha beta results in t cell unresponsiveness due to the induction of activation dependent cell death by apoptosis. |
1990-10-19 |
2023-08-11 |
Not clear |