| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W D Jarvis, R N Kolesnick, F A Fornari, R S Traylor, D A Gewirtz, S Gran. Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 1. 1994-02-04. PMID:8278410. |
the potential involvement of ceramide-related signaling processes in the induction of apoptosis by tumor necrosis factor alpha was assessed by multiple biochemical strategies in the human leukemic cell lines hl-60 and u937 and the murine fibrosarcoma cell lines l929/lm and wehi 164/13. |
1994-02-04 |
2023-08-12 |
human |
| W D Jarvis, R N Kolesnick, F A Fornari, R S Traylor, D A Gewirtz, S Gran. Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 1. 1994-02-04. PMID:8278410. |
exposure of these cells to tumor necrosis factor alpha resulted in internucleosomal cleavage of genomic dna, yielding laddered patterns of oligonucleosomal fragments characteristic of apoptosis when resolved by agarose gel electrophoresis; similar responses were observed after exposure to exogenous sphingomyelinase or synthetic ceramides. |
1994-02-04 |
2023-08-12 |
human |
| K Kuwakado, M Kubota, H Hirota, S Adachi, K Matsubara, Y Kasai, Y Akiyama, H Mikaw. Aphidicolin potentiates apoptosis induced by arabinosyl nucleosides in human myeloid leukemia cell lines. Biochemical pharmacology. vol 46. issue 11. 1994-01-24. PMID:8267640. |
we investigated the effect of aphidicolin, an inhibitor of dna polymerase alpha and delta, on the induction of apoptosis by arabinosyl nucleosides in a human promyelocytic leukemia cell line, hl-60. |
1994-01-24 |
2023-08-12 |
human |
| Y H Zhang, K Takahashi, G Z Jiang, M Kawai, M Fukada, T Yokoch. In vivo induction of apoptosis (programmed cell death) in mouse thymus by administration of lipopolysaccharide. Infection and immunity. vol 61. issue 12. 1993-12-22. PMID:8225580. |
this apoptosis in the thymus might be mediated mainly by the adrenal hormones, but it is likely that tumor necrosis factor alpha might also participate in it. |
1993-12-22 |
2023-08-12 |
mouse |
| M Sarih, V Souvannavong, S C Brown, A Ada. Silica induces apoptosis in macrophages and the release of interleukin-1 alpha and interleukin-1 beta. Journal of leukocyte biology. vol 54. issue 5. 1993-12-10. PMID:8228619. |
silica induces apoptosis in macrophages and the release of interleukin-1 alpha and interleukin-1 beta. |
1993-12-10 |
2023-08-12 |
Not clear |
| K Ober. Interferons in the management of neuroendocrine tumors and their possible mechanism of action. The Yale journal of biology and medicine. vol 65. issue 5. 1993-11-16. PMID:1340065. |
alpha interferons induce several nuclear enzymes such as 2'-5'-a synthetase, p-68 kinase, and mx-a proteins, which are involved in a downregulation of expression of growth factors, oncogenes, and peptide hormones, leading to anti-proliferation and/or apoptosis. |
1993-11-16 |
2023-08-11 |
Not clear |
| S T Palayoor, J L Humm, R W Atcher, J J Hines, R M Mackli. G2M arrest and apoptosis in murine T lymphoma cells following exposure to 212Bi alpha particle irradiation. Nuclear medicine and biology. vol 20. issue 6. 1993-11-16. PMID:8401380. |
g2m arrest and apoptosis in murine t lymphoma cells following exposure to 212bi alpha particle irradiation. |
1993-11-16 |
2023-08-12 |
Not clear |
| V A Illera, C E Perandones, L L Stunz, D A Mower, R F Ashma. Apoptosis in splenic B lymphocytes. Regulation by protein kinase C and IL-4. Journal of immunology (Baltimore, Md. : 1950). vol 151. issue 6. 1993-10-20. PMID:8376764. |
unstimulated cultures showed spontaneous apoptosis increasing gradually and monotonically from < 2 to 32% of b cells by 16 h. the rate of accumulation of apoptotic cells was reduced by the addition of il-4 or pma, but not by the inactive phorbol ester, 4 alpha pdd. |
1993-10-20 |
2023-08-12 |
mouse |
| M L Gougeon, S Garcia, J Heeney, R Tschopp, H Lecoeur, D Guetard, V Rame, C Dauguet, L Montagnie. Programmed cell death in AIDS-related HIV and SIV infections. AIDS research and human retroviruses. vol 9. issue 6. 1993-09-10. PMID:8102239. |
prevention of apoptosis could be obtained in the presence of a mixture of cytokines and the minimal signal necessary for this prevention was il-1 alpha and il-2. |
1993-09-10 |
2023-08-12 |
human |
| Y Yang, M S Vacchio, J D Ashwel. 9-cis-retinoic acid inhibits activation-driven T-cell apoptosis: implications for retinoid X receptor involvement in thymocyte development. Proceedings of the National Academy of Sciences of the United States of America. vol 90. issue 13. 1993-08-06. PMID:8392190. |
here we report that although retinoic acid has little inhibitory effect on activation-induced t-cell proliferation, it specifically prevents activation-induced apoptosis of t-cell hybridomas and antigen-specific deletion of immature cd4+cd8+ thymocytes from alpha beta t-cell receptor transgenic mice. |
1993-08-06 |
2023-08-12 |
mouse |
| O K Vintermyr, B T Gjertsen, M Lanotte, S O Døskelan. Microinjected catalytic subunit of cAMP-dependent protein kinase induces apoptosis in myeloid leukemia (IPC-81) cells. Experimental cell research. vol 206. issue 1. 1993-05-28. PMID:8387020. |
this made it possible to study the effect on apoptosis of microinjected catalytic (c alpha) and regulatory (ri alpha d199) subunits of camp-dependent protein kinase as well as of phosphatase inhibitors. |
1993-05-28 |
2023-08-12 |
rat |
| E Monti, E G Mimnaugh, B K Sinh. Synergistic interactions of etoposide and interleukin-1 alpha are not due to DNA damage in human melanoma cells. Biochimica et biophysica acta. vol 1180. issue 3. 1993-02-25. PMID:8422427. |
furthermore, il-1 alpha by itself or in combination with vp-16 did not cause significant fragmentation of cellular dna into oligomers, indicating programmed cell death (apoptosis) was not involved in the mechanism of synergy. |
1993-02-25 |
2023-08-12 |
human |
| J L Juengel, H A Garverick, A L Johnson, R S Youngquist, M F Smit. Apoptosis during luteal regression in cattle. Endocrinology. vol 132. issue 1. 1993-02-05. PMID:8419126. |
the present studies were conducted to evaluate whether apoptosis occurs during spontaneous and prostaglandin f2 alpha (pgf2 alpha)-induced luteolysis and, if so, to determine the relationship between the onset of luteolysis and oligonucleosome formation (a characteristic of apoptosis). |
1993-02-05 |
2023-08-12 |
cattle |
| M A Valentine, K A Licciard. Rescue from anti-IgM-induced programmed cell death by the B cell surface proteins CD20 and CD40. European journal of immunology. vol 22. issue 12. 1992-12-29. PMID:1280225. |
in contrast to the effect of pma, the 4 alpha pma isomer of pma neither activated protein kinase c (pkc) nor rescued the cells from anti-igm-induced pcd, confirming a role for pkc in negating apoptosis. |
1992-12-29 |
2023-08-11 |
human |
| M P Pender, P A McCombe, G Yoong, K B Nguye. Apoptosis of alpha beta T lymphocytes in the nervous system in experimental autoimmune encephalomyelitis: its possible implications for recovery and acquired tolerance. Journal of autoimmunity. vol 5. issue 4. 1992-12-17. PMID:1384526. |
light microscopic immunocytochemistry using the monoclonal antibodies ox-34 (cd2) and r73 (alpha beta t-cell receptor) revealed that 10% of the cd2+ cells and 5% of the alpha beta t lymphocytes in the parenchyma of the spinal cord were dying by apoptosis. |
1992-12-17 |
2023-08-11 |
rat |
| M P Pender, P A McCombe, G Yoong, K B Nguye. Apoptosis of alpha beta T lymphocytes in the nervous system in experimental autoimmune encephalomyelitis: its possible implications for recovery and acquired tolerance. Journal of autoimmunity. vol 5. issue 4. 1992-12-17. PMID:1384526. |
apoptosis of alpha beta t lymphocytes in the nervous system in experimental autoimmune encephalomyelitis: its possible implications for recovery and acquired tolerance. |
1992-12-17 |
2023-08-11 |
rat |
| H Pircher, K P Müller, B A Kyewski, H Hengartne. Thymocytes can tolerize thymocytes by clonal deletion in vitro. International immunology. vol 4. issue 9. 1992-11-16. PMID:1390437. |
antigen-induced apoptosis of immature thymocytes was inhibited by antibodies specific for the alpha beta tcr, cd3, cd8, and lfa-1 molecules. |
1992-11-16 |
2023-08-11 |
mouse |
| J Lotem, L Sach. Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor beta 1 and cancer chemotherapy compounds in myeloid leukemic cells. Blood. vol 80. issue 7. 1992-10-29. PMID:1382703. |
in the m1 myeloid leukemia, this induction of apoptosis was inhibited by granulocyte colony-stimulating factor (g-csf) or interleukin-6 (il-6) and to a lesser extent by il-1 alpha. |
1992-10-29 |
2023-08-11 |
Not clear |
| D M Brown, G L Warner, J E Alés-Martínez, D W Scott, R P Phipp. Prostaglandin E2 induces apoptosis in immature normal and malignant B lymphocytes. Clinical immunology and immunopathology. vol 63. issue 3. 1992-08-11. PMID:1623642. |
finally, using a recently devised flow cytometric method to study apoptosis in heterogeneous cell populations, we compared the ability of anti-igm, pge2, or pgf2 alpha to induce apoptosis in b lymphocytes from neonatal or adult mice. |
1992-08-11 |
2023-08-11 |
mouse |
| G Migliorati, C Pagliacci, R Moraca, F Crocicchio, I Nicoletti, C Riccard. Interleukins modulate glucocorticoid-induced thymocyte apoptosis. International journal of clinical & laboratory research. vol 21. issue 4. 1992-06-26. PMID:1591384. |
dose-response experiments indicated that interleukin-4 is more potent than interleukin-1 alpha and interleukin-2 in inhibiting dexamethasone-induced apoptosis. |
1992-06-26 |
2023-08-11 |
mouse |