| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V A Polunovsky, C H Wendt, D H Ingbar, M S Peterson, P B Bitterma. Induction of endothelial cell apoptosis by TNF alpha: modulation by inhibitors of protein synthesis. Experimental cell research. vol 214. issue 2. 1994-11-04. PMID:7925652. |
tnf alpha was able to induce bovine pulmonary artery endothelial cell apoptosis in a dose-dependent fashion. |
1994-11-04 |
2023-08-12 |
cattle |
| V A Polunovsky, C H Wendt, D H Ingbar, M S Peterson, P B Bitterma. Induction of endothelial cell apoptosis by TNF alpha: modulation by inhibitors of protein synthesis. Experimental cell research. vol 214. issue 2. 1994-11-04. PMID:7925652. |
inhibition of transcription with actinomycin d or translation with cycloheximide also resulted in apoptosis, which reached a maximum value of approximately 35 to 40% of cells after 24 h. tnf alpha induction of apoptosis was either potentiated or abrogated by cycloheximide, depending on the timing of tnf alpha exposure in relation to inhibition of protein synthesis. |
1994-11-04 |
2023-08-12 |
cattle |
| V A Polunovsky, C H Wendt, D H Ingbar, M S Peterson, P B Bitterma. Induction of endothelial cell apoptosis by TNF alpha: modulation by inhibitors of protein synthesis. Experimental cell research. vol 214. issue 2. 1994-11-04. PMID:7925652. |
when cycloheximide was added concomitantly with midrange concentrations of tnf alpha, there was both a dramatic acceleration and a synergistic increase in the observed apoptotic response, with all endothelial cells dying within 24 h. when cycloheximide was added as a function of time after termination of tnf alpha exposure, the synergistic induction of apoptosis was maintained at > 70% of its maximum value for 1 h, declining monotonically in a time-dependent fashion to baseline values after 6 h. in contrast, when tnf alpha was added after protein synthesis was inhibited, no additional increase in apoptosis above that observed with inhibition of protein synthesis alone was observed. |
1994-11-04 |
2023-08-12 |
cattle |
| V A Polunovsky, C H Wendt, D H Ingbar, M S Peterson, P B Bitterma. Induction of endothelial cell apoptosis by TNF alpha: modulation by inhibitors of protein synthesis. Experimental cell research. vol 214. issue 2. 1994-11-04. PMID:7925652. |
our results are consistent with the concept that endothelial cell viability depends on an interaction of inducers and suppressors of apoptosis, which are susceptible to modulation by tnf alpha. |
1994-11-04 |
2023-08-12 |
cattle |
| J F Zagury, A Lachgar, A Achour, V Chams-Harvey, Y Y Cho, H Le Coq, B Bizzini, M Feldman, A Burny, D Zagur. Pathogenic disorders involved in immunosuppression and T cell depletion characterizing AIDS. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 48. issue 1. 1994-10-25. PMID:7919098. |
furthermore, ifn alpha overproduction may also render circulating memory t cells competent to apoptosis by upregulating the cascade of metabolic events leading to programmed cell death. |
1994-10-25 |
2023-08-12 |
Not clear |
| A M Montgomery, R A Reisfeld, D A Cheres. Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 19. 1994-10-14. PMID:7522323. |
variant melanoma cells, lacking the alpha v subunit, progressed rapidly to apoptosis within this matrix, whereas transfection of these cells with an alpha v cdna restored alpha v beta 3 expression and prevented apoptosis. |
1994-10-14 |
2023-08-12 |
human |
| A M Montgomery, R A Reisfeld, D A Cheres. Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 19. 1994-10-14. PMID:7522323. |
integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. |
1994-10-14 |
2023-08-12 |
human |
| A M Montgomery, R A Reisfeld, D A Cheres. Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 19. 1994-10-14. PMID:7522323. |
apoptosis of alpha v(-) cells within this matrix could be overcome by the addition of insulin or serum. |
1994-10-14 |
2023-08-12 |
human |
| A Zychlinsky, C Fitting, J M Cavaillon, P J Sansonett. Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri. The Journal of clinical investigation. vol 94. issue 3. 1994-10-13. PMID:8083373. |
peritoneal macrophages undergoing apoptosis induced by shigella flexneri infection release the inflammatory cytokine interleukin 1 (il-1), but not il-6 or tumor necrosis factor alpha (tnf alpha). |
1994-10-13 |
2023-08-12 |
Not clear |
| S K Chiou, C C Tseng, L Rao, E Whit. Functional complementation of the adenovirus E1B 19-kilodalton protein with Bcl-2 in the inhibition of apoptosis in infected cells. Journal of virology. vol 68. issue 10. 1994-10-13. PMID:8083992. |
expression of bcl-2 in hela cells also conferred resistance to apoptosis mediated by tumor necrosis factor alpha and fas antigen, which is also an established function of the e1b 19k protein. |
1994-10-13 |
2023-08-12 |
human |
| G Fejer, I Gyory, J Tufariello, M S Horwit. Characterization of transgenic mice containing adenovirus early region 3 genomic DNA. Journal of virology. vol 68. issue 9. 1994-09-09. PMID:8057467. |
three other e3 proteins are involved in the inhibition of apoptosis by tumor necrosis factor alpha. |
1994-09-09 |
2023-08-12 |
mouse |
| C Borner, I Martinou, C Mattmann, M Irmler, E Schaerer, J C Martinou, J Tschop. The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis. The Journal of cell biology. vol 126. issue 4. 1994-09-06. PMID:8051205. |
the protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis. |
1994-09-06 |
2023-08-12 |
Not clear |
| C Borner, I Martinou, C Mattmann, M Irmler, E Schaerer, J C Martinou, J Tschop. The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis. The Journal of cell biology. vol 126. issue 4. 1994-09-06. PMID:8051205. |
a truncation mutant of bcl-2 alpha lacking the last 33 amino acids (t3.1) including the hydrophobic cooh terminus shows full activity in blocking apoptosis of nerve growth factor-deprived sympathetic neurons or tnf-alpha-treated l929 fibroblasts. |
1994-09-06 |
2023-08-12 |
Not clear |
| A Haimovitz-Friedman, C C Kan, D Ehleiter, R S Persaud, M McLoughlin, Z Fuks, R N Kolesnic. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. The Journal of experimental medicine. vol 180. issue 2. 1994-08-30. PMID:8046331. |
recent investigations provided evidence that the sphingomyelin signal transduction pathway mediates apoptosis for tumor necrosis factor alpha (tnf-alpha) in several hematopoietic and nonhematopoietic cells. |
1994-08-30 |
2023-08-12 |
cattle |
| T P Arstila, P Toivanen, O Vainio, O Lassil. Gamma delta and alpha beta T cells are equally susceptible to apoptosis. Scandinavian journal of immunology. vol 40. issue 2. 1994-08-30. PMID:8047843. |
gamma delta and alpha beta t cells are equally susceptible to apoptosis. |
1994-08-30 |
2023-08-12 |
chicken |
| T P Arstila, P Toivanen, O Vainio, O Lassil. Gamma delta and alpha beta T cells are equally susceptible to apoptosis. Scandinavian journal of immunology. vol 40. issue 2. 1994-08-30. PMID:8047843. |
these results indicate that gamma delta t cells are susceptible to apoptosis in a manner similar to alpha beta t cells, and suggest that apoptosis plays an important role in the regulation of the development and function of both thymic and peripheral gamma delta t cells. |
1994-08-30 |
2023-08-12 |
chicken |
| L Huang, K Sye, I N Crisp. Proliferation and apoptosis of B220+CD4-CD8-TCR alpha beta intermediate T cells in the liver of normal adult mice: implication for lpr pathogenesis. International immunology. vol 6. issue 4. 1994-08-04. PMID:7517176. |
proliferation and apoptosis of b220+cd4-cd8-tcr alpha beta intermediate t cells in the liver of normal adult mice: implication for lpr pathogenesis. |
1994-08-04 |
2023-08-12 |
mouse |
| J Gómez, A de la Hera, A Silva, C Pitton, A Garcia, A Rebell. Implication of protein kinase C in IL-2-mediated proliferation and apoptosis in a murine T cell clone. Experimental cell research. vol 213. issue 1. 1994-08-01. PMID:8020589. |
the use of the phorbol ester pma, a protein kinase c activator, allows a bypass of the il-2/il-2r interaction in the suppression of apoptosis mediated by dexamethasone or il-2 withdrawal in ts1 beta cells but not in ts1 alpha beta cells. |
1994-08-01 |
2023-08-12 |
Not clear |
| M Yamamoto, K Fujihashi, M Amano, J R McGhee, K W Beagley, H Kiyon. Cytokine synthesis and apoptosis by intestinal intraepithelial lymphocytes: signaling of high density alpha beta T cell receptor+ and gamma delta T cell receptor+ T cells via T cell receptor-CD3 complex results in interferon-gamma and interleukin-5 production, while low density T cells undergo DNA fragmentation. European journal of immunology. vol 24. issue 6. 1994-07-08. PMID:8206090. |
cytokine synthesis and apoptosis by intestinal intraepithelial lymphocytes: signaling of high density alpha beta t cell receptor+ and gamma delta t cell receptor+ t cells via t cell receptor-cd3 complex results in interferon-gamma and interleukin-5 production, while low density t cells undergo dna fragmentation. |
1994-07-08 |
2023-08-12 |
Not clear |
| S Cui, J S Reichner, R B Mateo, J E Albin. Activated murine macrophages induce apoptosis in tumor cells through nitric oxide-dependent or -independent mechanisms. Cancer research. vol 54. issue 9. 1994-05-24. PMID:8162595. |
macrophages also induced apoptosis in l929 cells but, in this case, apoptosis was no independent and partially inhibited in cocultures by an antitumor necrosis factor alpha monoclonal antibody. |
1994-05-24 |
2023-08-12 |
Not clear |