Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
T Mainou-Fowler, V A Craig, A J Copplestone, M D Hamon, A G Prentic. Effect of anti-APO1 on spontaneous apoptosis of B cells in chronic lymphocytic leukaemia: the role of bcl-2 and interleukin 4. Leukemia & lymphoma. vol 19. issue 3-4. 1996-02-08. PMID:8535223. |
we examined the effect of anti (alpha) apo1 ab on spontaneous apoptosis (sa) and bcl-2 expression in b cell chronic lymphocytic leukaemia (b-cll) in vitro. |
1996-02-08 |
2023-08-12 |
Not clear |
T Mainou-Fowler, V A Craig, A J Copplestone, M D Hamon, A G Prentic. Effect of anti-APO1 on spontaneous apoptosis of B cells in chronic lymphocytic leukaemia: the role of bcl-2 and interleukin 4. Leukemia & lymphoma. vol 19. issue 3-4. 1996-02-08. PMID:8535223. |
although expression of apo1 on b-cll cells was not detectable by immunofluorescence, alpha apo1 ab induced apoptosis in these cells. |
1996-02-08 |
2023-08-12 |
Not clear |
T Mainou-Fowler, V A Craig, A J Copplestone, M D Hamon, A G Prentic. Effect of anti-APO1 on spontaneous apoptosis of B cells in chronic lymphocytic leukaemia: the role of bcl-2 and interleukin 4. Leukemia & lymphoma. vol 19. issue 3-4. 1996-02-08. PMID:8535223. |
interleukin 4 significantly protected b-cll cells against alpha apo1-induced apoptosis by a mean of 53% (range: 28-76) (p < .001). |
1996-02-08 |
2023-08-12 |
Not clear |
T Mainou-Fowler, V A Craig, A J Copplestone, M D Hamon, A G Prentic. Effect of anti-APO1 on spontaneous apoptosis of B cells in chronic lymphocytic leukaemia: the role of bcl-2 and interleukin 4. Leukemia & lymphoma. vol 19. issue 3-4. 1996-02-08. PMID:8535223. |
thus alpha apo1 ab induced apoptosis in b-cll cells by a pathway that is independent of bcl-2 expression and partially blocked by il4. |
1996-02-08 |
2023-08-12 |
Not clear |
T Fernandes-Alnemri, A Takahashi, R Armstrong, J Krebs, L Fritz, K J Tomaselli, L Wang, Z Yu, C M Croce, G Salveso. Mch3, a novel human apoptotic cysteine protease highly related to CPP32. Cancer research. vol 55. issue 24. 1996-01-22. PMID:8521391. |
the high degree of conservation in structure and specific activity and the coexistence of mch3 alpha and cpp32 in the same cell suggests that the parp cleavage activity observed during apoptosis cannot solely be attributed to cpp32 but could also be an activity of mch3 alpha. |
1996-01-22 |
2023-08-12 |
human |
A Büssing, M Klotz, K Suzart, T Efferth, D Gerlach, N Schnitzler, R Osieka, K Schweizer, A Kaufhol. Sister chromatid exchange-inducing DNA lesions and depression of activation markers on the surface of cultured peripheral blood mononuclear cells after the addition of streptococcal pyrogenic exotoxins A and C. Medical microbiology and immunology. vol 184. issue 2. 1996-01-17. PMID:7500916. |
concomitantly, the expression of interleukin-2 receptor alpha chain (il-2r alpha chain), transferrin receptor (tfr), and major histocompatibility complex class ii molecule hla-dr on the surface of phytohemagglutinin-activated t cells from whole blood culture cells (wbcc) significantly decreased within 72 h, that is at least two cell cycles, whereas unstimulated t cells from wbcc did not express these markers but had lost their cd3 molecules, an effect reported to precede apoptosis as part of a t cell inactivation pathway. |
1996-01-17 |
2023-08-12 |
Not clear |
H Zhu, Y Shen, T Shen. Human cytomegalovirus IE1 and IE2 proteins block apoptosis. Journal of virology. vol 69. issue 12. 1996-01-11. PMID:7494309. |
the ie1 and ie2 proteins each inhibit the induction of apoptosis by tumor necrosis factor alpha or by the e1b 19-kda-protein-deficient adenovirus but not by irradiation with uv light. |
1996-01-11 |
2023-08-12 |
human |
L B King, M S Vacchio, K Dixon, R Hunziker, D H Margulies, J D Ashwel. A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development. Immunity. vol 3. issue 5. 1995-12-26. PMID:7584154. |
while an enhanced susceptibility to t cell receptor (tcr)-mediated apoptosis appeared to be partially responsible for this reduction, thymocyte loss could also be detected before thymocytes progressed to the cd4+cd8+ tcr alpha beta-expressing stage. |
1995-12-26 |
2023-08-12 |
mouse |
A T Baldé, J L Sarthou, C Roussilho. Acute Plasmodium falciparum infection is associated with increased percentages of apoptotic cells. Immunology letters. vol 46. issue 1-2. 1995-12-07. PMID:7590929. |
selective immunomagnetic cell isolations carried out immediately before apoptosis quantitation showed that this process affected not only the alpha beta t cells (cd4+ t cells as well as cd8+ t cells) but also the gamma delta t cells and the b-lymphocyte subset. |
1995-12-07 |
2023-08-12 |
human |
X R Yao, D W Scot. Independent signaling for growth arrest and apoptosis by Ig alpha and Ig beta subunits of the B-cell antigen receptor complex. Annals of the New York Academy of Sciences. vol 766. 1995-12-06. PMID:7486705. |
independent signaling for growth arrest and apoptosis by ig alpha and ig beta subunits of the b-cell antigen receptor complex. |
1995-12-06 |
2023-08-12 |
Not clear |
P Després, J W Griffin, D E Griffi. Antiviral activity of alpha interferon in Sindbis virus-infected cells is restored by anti-E2 monoclonal antibody treatment. Journal of virology. vol 69. issue 11. 1995-12-01. PMID:7474167. |
pretreatment of at3 rat prostatic carcinoma cells expressing the inhibitor of apoptosis bcl-2 (at3-bcl-2 cells) with alpha interferon (ifn-alpha) affected replication of a virulent strain of sindbis virus (sv) but did not protect against virus-induced cell death. |
1995-12-01 |
2023-08-12 |
rat |
J A Flaws, K Kugu, A M Trbovich, A DeSanti, K I Tilly, A N Hirshfield, J L Till. Interleukin-1 beta-converting enzyme-related proteases (IRPs) and mammalian cell death: dissociation of IRP-induced oligonucleosomal endonuclease activity from morphological apoptosis in granulosa cells of the ovarian follicle. Endocrinology. vol 136. issue 11. 1995-11-27. PMID:7588240. |
granulosa cells within follicles incubated in medium alone exhibited extensive levels of apoptosis, and this onset of apoptosis was prevented by the inclusion of tgf alpha. |
1995-11-27 |
2023-08-12 |
rat |
R Fuller, M Johnson, A By. Fluticasone propionate--an update on preclinical and clinical experience. Respiratory medicine. vol 89 Suppl A. 1995-11-22. PMID:7569173. |
in vitro, fp has been shown to potently inhibit t lymphocyte proliferation, cytokine generation, tumour necrosis factor alpha (tnf-alpha)-induced adhesion molecule expression, interleukin-5-induced eosinophilia, mucosal oedema and toluene 2,4-diisocyanate-induced mast cell proliferation, while promoting secretory leucocyte protease inhibitor production and eosinophil apoptosis. |
1995-11-22 |
2023-08-12 |
human |
A S Clarke, M M Lotz, C Chao, A M Mercuri. Activation of the p21 pathway of growth arrest and apoptosis by the beta 4 integrin cytoplasmic domain. The Journal of biological chemistry. vol 270. issue 39. 1995-11-06. PMID:7559386. |
in this study, we report that subclones that expressed the full-length beta 4 cdna in association with endogenous alpha 6 exhibited partial g1 arrest and apoptosis, properties that were not evident in rko cells transfected with either the cytoplasmic domain mutant or the expression vector alone. |
1995-11-06 |
2023-08-12 |
Not clear |
W J Murdoc. Temporal relationships between stress protein induction, progesterone withdrawal, and apoptosis in corpora lutea of ewes treated with prostaglandin F2 alpha. Journal of animal science. vol 73. issue 6. 1995-10-19. PMID:7673073. |
temporal relationships between stress protein induction, progesterone withdrawal, and apoptosis in corpora lutea of ewes treated with prostaglandin f2 alpha. |
1995-10-19 |
2023-08-12 |
Not clear |
C B Powell, T J Herzog, J H Scott, J L Collin. Evidence for a protein synthesis-dependent and -independent TNF alpha cytolytic mechanism. Gynecologic oncology. vol 58. issue 3. 1995-10-17. PMID:7545633. |
both tnf alpha cytolytic mechanisms cause apoptosis (fragmentation of dna) as shown by the tnf alpha-mediated release of tritiated thymidine, apoptag, and dapi staining, in the presence or absence of em or act-d. |
1995-10-17 |
2023-08-12 |
Not clear |
D Rogaia, F Grignani, F Grignani, I Nicoletti, P G Pelicc. The acute promyelocytic leukemia-specific PML/RAR alpha fusion protein reduces the frequency of commitment to apoptosis upon growth factor deprivation of GM-CSF-dependent myeloid cells. Leukemia. vol 9. issue 9. 1995-10-05. PMID:7658713. |
the acute promyelocytic leukemia-specific pml/rar alpha fusion protein reduces the frequency of commitment to apoptosis upon growth factor deprivation of gm-csf-dependent myeloid cells. |
1995-10-05 |
2023-08-12 |
Not clear |
D Rogaia, F Grignani, F Grignani, I Nicoletti, P G Pelicc. The acute promyelocytic leukemia-specific PML/RAR alpha fusion protein reduces the frequency of commitment to apoptosis upon growth factor deprivation of GM-CSF-dependent myeloid cells. Leukemia. vol 9. issue 9. 1995-10-05. PMID:7658713. |
we conclude that pml/rar alpha interferes with the genetic pathways which regulate survival by reducing the frequency of commitment to apoptosis. |
1995-10-05 |
2023-08-12 |
Not clear |
I Corre, S Hermoue. Regulation of colony-stimulating factor 1-induced proliferation by heterotrimeric Gi2 proteins. Blood. vol 86. issue 5. 1995-10-03. PMID:7655008. |
we show that expression of alpha i2-q205l in bac 1.2f5 cells does not induce independence from csf 1, but reduces the cells' requirement in csf 1, shortens the length of the g1 phase and the cell doubling time in response to csf 1, and protects cells from death by apoptosis induced by csf 1 withdrawal, exposure to h2o2 or heat shock, but not mitoxantrone. |
1995-10-03 |
2023-08-12 |
Not clear |
M Minegishi, N Minegishi, T Yanagisawa, S Tsuchiya, H Tezuka, M Kaji, M Nakamura, Y Hayashi, T Konn. A human CD4- CD8- T-cell receptor alpha beta + T leukemic cell line undergoing phytohemagglutinin-induced apoptosis. Leukemia research. vol 19. issue 7. 1995-09-11. PMID:7543637. |
a human cd4- cd8- t-cell receptor alpha beta + t leukemic cell line undergoing phytohemagglutinin-induced apoptosis. |
1995-09-11 |
2023-08-12 |
human |