| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Nakamura, Y Shidoji, H Moriwaki, Y Mut. Apoptosis in human hepatoma cell line induced by 4,5-didehydro geranylgeranoic acid (acyclic retinoid) via down-regulation of transforming growth factor-alpha. Biochemical and biophysical research communications. vol 219. issue 1. 1996-06-13. PMID:8619789. |
either exogenous transforming growth factor-alpha (tgf alpha) or epidermal growth factor(egf) prevented the cells from apoptosis in the presence of 4,5-didehydro gga, but hepatocyte growth factor, insulin-like growth factor-ii, insulin or triiodothyronine was essentially inactive. |
1996-06-13 |
2023-08-12 |
human |
| N Nakamura, Y Shidoji, H Moriwaki, Y Mut. Apoptosis in human hepatoma cell line induced by 4,5-didehydro geranylgeranoic acid (acyclic retinoid) via down-regulation of transforming growth factor-alpha. Biochemical and biophysical research communications. vol 219. issue 1. 1996-06-13. PMID:8619789. |
either anti-tgf alpha or anti-egf receptor monoclonal antibody induced apoptosis in huh-7 cells without using the acid. |
1996-06-13 |
2023-08-12 |
human |
| N Nakamura, Y Shidoji, H Moriwaki, Y Mut. Apoptosis in human hepatoma cell line induced by 4,5-didehydro geranylgeranoic acid (acyclic retinoid) via down-regulation of transforming growth factor-alpha. Biochemical and biophysical research communications. vol 219. issue 1. 1996-06-13. PMID:8619789. |
taken together, the present study strongly suggests that 4,5-didehydro gga induced apoptosis in huh-7 cells through the destruction of autocrine loop consisting of tgf alpha and egf receptor, due to the down regulation of tgf alpha gene expression. |
1996-06-13 |
2023-08-12 |
human |
| V O'Brien, S M Frisch, R L Julian. Expression of the integrin alpha 5 subunit in HT29 colon carcinoma cells suppresses apoptosis triggered by serum deprivation. Experimental cell research. vol 224. issue 1. 1996-06-05. PMID:8612688. |
expression of the integrin alpha 5 subunit in ht29 colon carcinoma cells suppresses apoptosis triggered by serum deprivation. |
1996-06-05 |
2023-08-12 |
human |
| V O'Brien, S M Frisch, R L Julian. Expression of the integrin alpha 5 subunit in HT29 colon carcinoma cells suppresses apoptosis triggered by serum deprivation. Experimental cell research. vol 224. issue 1. 1996-06-05. PMID:8612688. |
in the present study we have used ht29 human colon carcinoma cells stably transfected with human cdna for the integrin alpha 5 subunit and studied the effects of alpha 5 expression on the induction of apoptosis. |
1996-06-05 |
2023-08-12 |
human |
| V O'Brien, S M Frisch, R L Julian. Expression of the integrin alpha 5 subunit in HT29 colon carcinoma cells suppresses apoptosis triggered by serum deprivation. Experimental cell research. vol 224. issue 1. 1996-06-05. PMID:8612688. |
we observe that apoptosis can be triggered in ht29 cells by removal of serum and that this process can be suppressed by the stable expression of full-length integrin alpha 5 subunits. |
1996-06-05 |
2023-08-12 |
human |
| C Calabresse, S Barbey, L Venturini, N Balitrand, L Degos, P Fenaux, C Chomienn. In vitro treatment with retinoids or the topoisomerase inhibitor, VP-16, evidences different functional apoptotic pathways in acute promyelocytic leukemic cells. Leukemia. vol 9. issue 12. 1996-05-29. PMID:8609716. |
treatment of apl cells with 9-cis ra, 13-cis ra or analogs of rar alpha or rxr alpha also failed to induce apoptosis. |
1996-05-29 |
2023-08-12 |
Not clear |
| P O Iversen, L B To, A F Lope. Apoptosis of hemopoietic cells by the human granulocyte-macrophage colony-stimulating factor mutant E21R. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 7. 1996-05-24. PMID:8610118. |
these findings support a model whereby binding of e21r to the alpha chain leads to apoptosis, while beta(c) plays an important role in cell survival. |
1996-05-24 |
2023-08-12 |
human |
| E Isogai, H Isogal, K Kimura, N Fujii, S Takagi, K Hirose, M Hayash. In vivo induction of apoptosis and immune responses in mice by administration of lipopolysaccharide from Porphyromonas gingivalis. Infection and immunity. vol 64. issue 4. 1996-05-23. PMID:8606120. |
tumor necrosis factor alpha (tnf-alpha) could mediate apoptosis, because the serum tnf-alpha levels were significantly higher than those of controls at 1 day before apoptosis and recombinant murine tnf-alpha induced apoptosis. |
1996-05-23 |
2023-08-12 |
mouse |
| b' C L Tucek-Szabo, S Andjeli\\xc4\\x87, E Lacy, K B Elkon, J Nikoli\\xc4\\x87-Zugi\\xc4\\x8. Surface T cell Fas receptor/CD95 regulation, in vivo activation, and apoptosis. Activation-induced death can occur without Fas receptor. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 1. 1996-04-23. PMID:8598462.' |
most importantly, mrl-ipr/ipr t cells underwent massive activation-induced apoptosis in response to high and intermediate doses of alpha cd3. |
1996-04-23 |
2023-08-12 |
Not clear |
| b' C L Tucek-Szabo, S Andjeli\\xc4\\x87, E Lacy, K B Elkon, J Nikoli\\xc4\\x87-Zugi\\xc4\\x8. Surface T cell Fas receptor/CD95 regulation, in vivo activation, and apoptosis. Activation-induced death can occur without Fas receptor. Journal of immunology (Baltimore, Md. : 1950). vol 156. issue 1. 1996-04-23. PMID:8598462.' |
at a low alpha cd3 dose, however, both mrl-ipr/ipr and mrl +/+ t cells were activated similarly, but only the latter underwent adequate apoptosis. |
1996-04-23 |
2023-08-12 |
Not clear |
| Y Q Zhang, M Kanzaki, H Mashima, T Mine, I Kojim. Norepinephrine reverses the effects of activin A on DNA synthesis and apoptosis in cultured rat hepatocytes. Hepatology (Baltimore, Md.). vol 23. issue 2. 1996-04-03. PMID:8591854. |
these results indicate that ne, acting on alpha 1-adrenergic receptors, attenuates the effects of activin a on dna synthesis by and apoptosis of cultured rat hepatocytes. |
1996-04-03 |
2023-08-12 |
rat |
| E U Saelman, P J Keely, S A Santor. Loss of MDCK cell alpha 2 beta 1 integrin expression results in reduced cyst formation, failure of hepatocyte growth factor/scatter factor-induced branching morphogenesis, and increased apoptosis. Journal of cell science. vol 108 ( Pt 11). 1996-03-25. PMID:8586664. |
loss of mdck cell alpha 2 beta 1 integrin expression results in reduced cyst formation, failure of hepatocyte growth factor/scatter factor-induced branching morphogenesis, and increased apoptosis. |
1996-03-25 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
here we report that tnf alpha mediates apoptosis in kc and sinusoidal endothelial cells. |
1996-03-25 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
tnf alpha antibody blocked apoptosis in both kc and endothelial cells. |
1996-03-25 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
reducing transmembrane tnf alpha expressed on kc also led to a decrease in endothelial cell apoptosis, suggesting that transmembrane tnf alpha is implicated in the cell-to-cell contact mechanism of induction of apoptosis. |
1996-03-25 |
2023-08-12 |
Not clear |
| Y Takei, S Kawano, Y Nishimura, M Goto, H Nagai, S S Chen, A Omae, H Fusamoto, T Kamada, K Iked. Apoptosis: a new mechanism of endothelial and Kupffer cell killing. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589347. |
thus, tnf alpha mediates apoptosis in kc and endothelial cells. |
1996-03-25 |
2023-08-12 |
Not clear |
| C M Swanink, J H Vercoulen, J M Galama, M T Roos, L Meyaard, J van der Ven-Jongekrijg, R de Nijs, G Bleijenberg, J F Fennis, F Miedema, J W van der Mee. Lymphocyte subsets, apoptosis, and cytokines in patients with chronic fatigue syndrome. The Journal of infectious diseases. vol 173. issue 2. 1996-03-05. PMID:8568312. |
there was no obvious difference in apoptosis in leukocyte cultures, circulating cytokines, and ex vivo production of interleukin (il)-1 alpha and il-1 receptor antagonist. |
1996-03-05 |
2023-08-12 |
Not clear |
| P Panayiotidis, D Jones, K Ganeshaguru, L Foroni, A V Hoffbran. Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro. British journal of haematology. vol 92. issue 1. 1996-03-01. PMID:8562418. |
leukaemic cells from most cases of b-chronic lymphocytic leukaemia die rapidly by apoptosis in vitro unless they are cultured in the presence of interleukin-4 or interferon alpha or gamma. |
1996-03-01 |
2023-08-12 |
human |
| F Spinozzi, I Nicoletti, E Agea, S Belia, R Moraca, G Migliorati, C Riccardi, F Grignani, A Bertott. IL-4 is able to reverse the CD2-mediated negative apoptotic signal to CD4-CD8- alpha beta and/or gamma delta T lymphocytes. Immunology. vol 86. issue 3. 1996-02-20. PMID:8550074. |
induction of apoptosis was prevented by the presence of interleukin-4 (il-4) as well as by endonuclease inactivation with 100 microm zncl2, but enhanced by the contemporary block of protein kinase c. thus it seems that in resting t lymphocytes the strong calcium signal delivered by the alternative cd2 activation pathway may act as a negative apoptotic signal in both alpha beta and gamma delta t cells with low (non-major histocompatibility complex restricted) antigenic affinity, so limiting the extension of polyclonal t-cell growth. |
1996-02-20 |
2023-08-12 |
Not clear |