| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Kaipia, S Y Chun, K Eisenhauer, A J Hsue. Tumor necrosis factor-alpha and its second messenger, ceramide, stimulate apoptosis in cultured ovarian follicles. Endocrinology. vol 137. issue 11. 1996-12-17. PMID:8895358. |
to study the mechanism of tnf alpha and ceramide action, the effect of sodium aurathiomalate (atm), an inhibitor of interleukin-1 beta-converting enzyme/ced-3-related cystine proteases known to be essential in the execution of mammalian cell apoptosis, was studied. |
1996-12-17 |
2023-08-12 |
rat |
| A Kaipia, S Y Chun, K Eisenhauer, A J Hsue. Tumor necrosis factor-alpha and its second messenger, ceramide, stimulate apoptosis in cultured ovarian follicles. Endocrinology. vol 137. issue 11. 1996-12-17. PMID:8895358. |
treatment with atm (1 mm) prevented the apoptosis-inducing effect of both tnf alpha and ceramide, suggesting a role for cysteine proteases in mediating follicle apoptosis. |
1996-12-17 |
2023-08-12 |
rat |
| A Kaipia, S Y Chun, K Eisenhauer, A J Hsue. Tumor necrosis factor-alpha and its second messenger, ceramide, stimulate apoptosis in cultured ovarian follicles. Endocrinology. vol 137. issue 11. 1996-12-17. PMID:8895358. |
in summary, treatment with tnf alpha or its second messenger, ceramide, stimulates apoptosis of early antral follicles in culture, suggesting a potential role for tnf alpha as an intraovarian regulator of follicle atresia by acting through the ceramide signaling pathway. |
1996-12-17 |
2023-08-12 |
rat |
| D J Van Antwerp, S J Martin, T Kafri, D R Green, I M Verm. Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science (New York, N.Y.). vol 274. issue 5288. 1996-12-10. PMID:8864120. |
tumor necrosis factor alpha (tnf-alpha) signaling gives rise to a number of events, including activation of transcription factor nf-kappab and programmed cell death (apoptosis). |
1996-12-10 |
2023-08-12 |
Not clear |
| G Baier-Bitterlich, H Wachter, D Fuch. Role of neopterin and 7,8-dihydroneopterin in human immunodeficiency virus infection: marker for disease progression and pathogenic link. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association. vol 13. issue 2. 1996-12-09. PMID:8862284. |
indeed, 7,8-dihydroneopterin is able to enhance tumor necrosis factor alpha (tnf-alpha)-induced apoptosis, accompanied by an increased production of reactive oxygen intermediates (rois). |
1996-12-09 |
2023-08-12 |
human |
| P A McCombe, I Nickson, Z Tabi, M P Pende. Corticosteroid treatment of experimental autoimmune encephalomyelitis in the Lewis rat results in loss of V beta 8.2+ and myelin basic protein-reactive cells from the spinal cord, with increased total T-cell apoptosis but reduced apoptosis of V beta 8.2+ cells. Journal of neuroimmunology. vol 70. issue 2. 1996-12-05. PMID:8898717. |
this increased level of apoptosis was observed in the cd5+ and tcr alpha beta + cell populations. |
1996-12-05 |
2023-08-12 |
rat |
| M Moore, N Horikoshi, T Shen. Oncogenic potential of the adenovirus E4orf6 protein. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 21. 1996-12-04. PMID:8876129. |
the e4orf6 protein does not, however, prevent the induction of apoptosis in p53-deficient h1299 cells by treatment with tumor necrosis factor alpha and cycloheximide. |
1996-12-04 |
2023-08-12 |
mouse |
| B S Polla, A Cossarizz. Stress proteins in inflammation. EXS. vol 77. 1996-12-03. PMID:8856986. |
we propose that mitochondria are a key organelle in determining the outcome of inflammation, because they are both the cellular "switchboard" for apoptosis and a selective target for the protective effects of hsp against the cytotoxic effects of tnf alpha and ros. |
1996-12-03 |
2023-08-12 |
Not clear |
| M J Pollman, T Yamada, M Horiuchi, G H Gibbon. Vasoactive substances regulate vascular smooth muscle cell apoptosis. Countervailing influences of nitric oxide and angiotensin II. Circulation research. vol 79. issue 4. 1996-11-27. PMID:8831498. |
the mediator role of the guanylate cyclase signaling pathway in no-induced apoptosis was evidenced by (1) induction of apoptosis by the 8-bromo-cgmp analogue, (2) potentiation of no-induced apoptosis by cgmp-specific phosphodiesterase inhibition, and (3) the prevention of no-induced apoptosis by the inhibition of the cgmp-dependent protein kinase 1 alpha. |
1996-11-27 |
2023-08-12 |
Not clear |
| T Nakajim. [Degradation of topoisomerase II alpha precedes nuclei degeneration during adenovirus E1A-induced apoptosis and is mediated by the activation of the ubiquitin dependent proteolysis system]. Nihon rinsho. Japanese journal of clinical medicine. vol 54. issue 7. 1996-11-26. PMID:8741674. |
[degradation of topoisomerase ii alpha precedes nuclei degeneration during adenovirus e1a-induced apoptosis and is mediated by the activation of the ubiquitin dependent proteolysis system]. |
1996-11-26 |
2023-08-12 |
human |
| T Nakajim. [Degradation of topoisomerase II alpha precedes nuclei degeneration during adenovirus E1A-induced apoptosis and is mediated by the activation of the ubiquitin dependent proteolysis system]. Nihon rinsho. Japanese journal of clinical medicine. vol 54. issue 7. 1996-11-26. PMID:8741674. |
the decrease of topoisomerase ii alpha was suppressed in the ma1 derivative e1b19k or bcl-2 expressing cell lines that refractory to e1a-induced apoptosis. |
1996-11-26 |
2023-08-12 |
human |
| T Nakajim. [Degradation of topoisomerase II alpha precedes nuclei degeneration during adenovirus E1A-induced apoptosis and is mediated by the activation of the ubiquitin dependent proteolysis system]. Nihon rinsho. Japanese journal of clinical medicine. vol 54. issue 7. 1996-11-26. PMID:8741674. |
these data suggest that degradation of topoisomerase ii alpha is a key event that destines cells to apoptosis, and is catalyzed by the ubiquitin proteolysis pathway that is activated during the latent phase of e1a-induced apoptosis. |
1996-11-26 |
2023-08-12 |
human |
| S Rich, N Van Nood, H M Le. Role of alpha 5 beta 1 integrin in TGF-beta 1-costimulated CD8+ T cell growth and apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 157. issue 7. 1996-11-25. PMID:8816397. |
role of alpha 5 beta 1 integrin in tgf-beta 1-costimulated cd8+ t cell growth and apoptosis. |
1996-11-25 |
2023-08-12 |
Not clear |
| S Rich, N Van Nood, H M Le. Role of alpha 5 beta 1 integrin in TGF-beta 1-costimulated CD8+ T cell growth and apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 157. issue 7. 1996-11-25. PMID:8816397. |
rgd peptides and alpha 5 integrin-specific ab abolished tgf-beta 1 prevention of activation-induced apoptosis. |
1996-11-25 |
2023-08-12 |
Not clear |
| S Rich, N Van Nood, H M Le. Role of alpha 5 beta 1 integrin in TGF-beta 1-costimulated CD8+ T cell growth and apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 157. issue 7. 1996-11-25. PMID:8816397. |
therefore, tgf-beta 1 costimulates cd8+ t cell growth via activation of the alpha 5 beta 1 integrin and/or its ligand and supports sustained growth at least in part by alpha 5 beta 1-mediated protection from activation-induced apoptosis. |
1996-11-25 |
2023-08-12 |
Not clear |
| S J Nass, M Li, L T Amundadottir, P A Furth, R B Dickso. Role for Bcl-xL in the regulation of apoptosis by EGF and TGF beta 1 in c-myc overexpressing mammary epithelial cells. Biochemical and biophysical research communications. vol 227. issue 1. 1996-11-25. PMID:8858133. |
we previously showed that tgf alpha synergizes with c-myc in mammary tumorigenesis through inhibition of myc-induced apoptosis. |
1996-11-25 |
2023-08-12 |
mouse |
| G Monastra, A Cabrelle, A Zambon, A Rosato, B Macino, D Collavo, P Zanovell. Membrane form of TNF alpha induces both cell lysis and apoptosis in susceptible target cells. Cellular immunology. vol 171. issue 1. 1996-11-22. PMID:8660844. |
membrane form of tnf alpha induces both cell lysis and apoptosis in susceptible target cells. |
1996-11-22 |
2023-08-12 |
Not clear |
| F Novelli, P Bernabei, L Ozmen, L Rigamonti, A Allione, S Pestka, G Garotta, G Forn. Switching on of the proliferation or apoptosis of activated human T lymphocytes by IFN-gamma is correlated with the differential expression of the alpha- and beta-chains of its receptor. Journal of immunology (Baltimore, Md. : 1950). vol 157. issue 5. 1996-11-22. PMID:8757312. |
this apoptosis, too, was prevented by the anti-ifn-gamma r alpha mab. |
1996-11-22 |
2023-08-12 |
human |
| O Billaut-Mulot, R Fernandez-Gomez, M Loyens, A Ouaiss. Trypanosoma cruzi elongation factor 1-alpha: nuclear localization in parasites undergoing apoptosis. Gene. vol 174. issue 1. 1996-11-21. PMID:8863724. |
furthermore, treatment of parasites with the antibiotic drug geneticin (g418) which induces the death of epimastigotes by apoptosis showed selective localization of ef-1 alpha in the nucleus of dying parasites. |
1996-11-21 |
2023-08-12 |
Not clear |
| R U Jänicke, X Y Lin, F H Lee, A G Porte. Cyclin D3 sensitizes tumor cells to tumor necrosis factor-induced, c-Myc-dependent apoptosis. Molecular and cellular biology. vol 16. issue 10. 1996-11-15. PMID:8816437. |
c-myc is an important mediator of apoptosis in cytokine- or serum-deprived cells and sensitizes various cell types to tumor necrosis factor alpha (tnf) cytotoxicity. |
1996-11-15 |
2023-08-12 |
Not clear |