| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Dricu, M Carlberg, M Wang, O Larsso. Inhibition of N-linked glycosylation using tunicamycin causes cell death in malignant cells: role of down-regulation of the insulin-like growth factor 1 receptor in induction of apoptosis. Cancer research. vol 57. issue 3. 1997-02-20. PMID:9012488. |
incubation of the cells with an antibody (alpha ir-3) against the igf-i-binding site of the receptor resulted also in apoptosis, the kinetics of which were almost identical to those following treatment with tm. |
1997-02-20 |
2023-08-12 |
Not clear |
| K Takamuku, K Baba, S Arinaga, J Li, M Mori, T Akiyosh. Apoptosis in antibody-dependent monocyte-mediated cytotoxicity with monoclonal antibody 17-1A against human colorectal carcinoma cells: enhancement with interferon gamma. Cancer immunology, immunotherapy : CII. vol 43. issue 4. 1997-02-19. PMID:9003467. |
however, the release of tumor necrosis factor alpha (tnf alpha) was significantly enhanced during admc, while, in addition, apoptosis was significantly inhibited by the addition of anti-tnf alpha antibody. |
1997-02-19 |
2023-08-12 |
human |
| K Takamuku, K Baba, S Arinaga, J Li, M Mori, T Akiyosh. Apoptosis in antibody-dependent monocyte-mediated cytotoxicity with monoclonal antibody 17-1A against human colorectal carcinoma cells: enhancement with interferon gamma. Cancer immunology, immunotherapy : CII. vol 43. issue 4. 1997-02-19. PMID:9003467. |
these findings indicated that apoptosis might be implicated in admc with mab 17-1a, which was augmented by ifn gamma, while, in addition, tnf alpha may also be one of the major mediators of apoptosis. |
1997-02-19 |
2023-08-12 |
human |
| Z Cai, M Körner, N Tarantino, S Chouai. IkappaB alpha overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-kappaB activation but not tumor necrosis factor-alpha-induced apoptosis. The Journal of biological chemistry. vol 272. issue 1. 1997-02-18. PMID:8995233. |
ikappab alpha overexpression in human breast carcinoma mcf7 cells inhibits nuclear factor-kappab activation but not tumor necrosis factor-alpha-induced apoptosis. |
1997-02-18 |
2023-08-12 |
human |
| H J Brady, G Gil-Gómez, J Kirberg, A J Bern. Bax alpha perturbs T cell development and affects cell cycle entry of T cells. The EMBO journal. vol 15. issue 24. 1997-02-13. PMID:9003775. |
bax alpha can heterodimerize with bcl-2 and bcl-x(l), countering their effects, as well as promoting apoptosis on overexpression. |
1997-02-13 |
2023-08-12 |
mouse |
| N Rouquet, J C Pagès, T Molina, P Briand, V Jouli. ICE inhibitor YVADcmk is a potent therapeutic agent against in vivo liver apoptosis. Current biology : CB. vol 6. issue 9. 1997-02-06. PMID:8805375. |
ligand-bound fas and tumour necrosis factor alpha (tnf-alpha) induce hepatic apoptosis in mice [3-6]. |
1997-02-06 |
2023-08-12 |
mouse |
| D Puthier, R Bataille, S Barillé, M P Mellerin, J L Harousseau, A Ponzio, N Robillard, J Wijdenes, M Amio. Myeloma cell growth arrest, apoptosis, and interleukin-6 receptor modulation induced by EB1089, a vitamin D3 derivative, alone or in association with dexamethasone. Blood. vol 88. issue 12. 1997-02-06. PMID:8977259. |
in the current study, we show that eb1089, a new vitamin d3 derivative, (1) induces g1 growth arrest of human myeloma cells, which is only partially reversed by interleukin-6 (il-6); (2) induces apoptosis in synergy with dexamethasone, il-6, leukemia-inhibitory factor, and oncostatin m, with an agonistic anti-gp130 monoclonal antibody being unable to prevent this apoptosis; (3) downregulates both the gp80 (ie, the alpha chain of the il-6 receptor [il-6ralpha]) expression on malignant plasma cells and the production of soluble il-6ralpha, and finally (4) inhibits the deleterious upregulation of gp80 expression induced by dexamethasone while limiting the dexamethasone-induced upregulation of gp130 expression. |
1997-02-06 |
2023-08-12 |
human |
| G Zauli, S Capitan. HIV-1-related mechanisms of suppression of CD34+ hematopoietic progenitors. Pathobiology : journal of immunopathology, molecular and cellular biology. vol 64. issue 1. 1997-02-03. PMID:8856796. |
in fact, it has been shown that: (i) infection with hiv-1 and/or exposure of bone marrow accessory cells to envelope glycoprotein 120 (env gp 120) increases the production of inhibitory cytokines such as tumor necrosis factor alpha; (ii) a subset of cd34+ hematopoietic progenitor cells co-expresses the cd4 antigen and may be infected in vivo with hiv-1; (iii) hiv-1 virions or immune complexes containing env gp 120 are able to induce apoptosis of uninfected cd34+ hematopoietic progenitors. |
1997-02-03 |
2023-08-12 |
human |
| S Dimmeler, J Haendeler, V Rippmann, M Nehls, A M Zeihe. Shear stress inhibits apoptosis of human endothelial cells. FEBS letters. vol 399. issue 1-2. 1997-01-31. PMID:8980122. |
to test the hypothesis that shear stress interferes with programmed cell death, apoptosis was induced in human umbilical venous endothelial cells by growth factor withdrawal or incubation with tumor necrosis factor alpha (tnfalpha) for 18 h. apoptosis was quantified by elisa specific for histone-associated dna fragments and confirmed by demonstrating the specific pattern of internucleosomal dna fragmentation detected by electrophoresis and immunohistochemical staining. |
1997-01-31 |
2023-08-12 |
human |
| M S Vincent, K Roessner, D Lynch, D Wilson, S M Cooper, J Tschopp, L H Sigal, R C Bud. Apoptosis of Fashigh CD4+ synovial T cells by borrelia-reactive Fas-ligand(high) gamma delta T cells in Lyme arthritis. The Journal of experimental medicine. vol 184. issue 6. 1997-01-30. PMID:8976167. |
furthermore, synovial gamma delta t cell clones express elevated and sustained levels of the ligand for fas (apo-1, cd95) compared to alpha beta t cells, and induce apoptosis of fashigh cd4+ synovial lymphocytes. |
1997-01-30 |
2023-08-12 |
human |
| I Dürrbaum-Landmann, J Gercken, H D Flad, M Erns. Effect of in vitro infection of human monocytes with low numbers of Mycobacterium tuberculosis bacteria on monocyte apoptosis. Infection and immunity. vol 64. issue 12. 1997-01-08. PMID:8945591. |
our data suggest that apoptosis of monocytes appears to be negatively associated with the presence of tumor necrosis factor alpha. |
1997-01-08 |
2023-08-12 |
human |
| K Xie, S Huang, Y Wang, P J Beltran, S H Juang, Z Dong, J C Reed, T J McDonnell, D J McConkey, I J Fidle. Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis. Cancer immunology, immunotherapy : CII. vol 43. issue 2. 1997-01-02. PMID:8954145. |
the incubation of murine l929 and nih3t3 cells with interleukin-1 alpha (il-1 alpha) and interferon gamma (ifn gamma) induced high endogenous no production only in the l929 cells that also underwent apoptosis. |
1997-01-02 |
2023-08-12 |
mouse |
| M Perrin-Wolff, Z Mishal, J Bertoglio, M Pallard. Position 16 of the steroid nucleus modulates glucocorticoid-induced apoptosis at the transcriptional level in murine T-lymphocytes. Biochemical pharmacology. vol 52. issue 9. 1996-12-31. PMID:8937459. |
we analysed this structure-function relationship between dexamethasone (dex; methyl group in position 16 alpha) and beta-methasone (bm; methyl group in position 16 beta) with regard to two important aspects of gc activity, namely the activation of transcription and induction of apoptosis in il-2-dependent murine lymphoid cells. |
1996-12-31 |
2023-08-12 |
Not clear |
| P A McCombe, I Nickson, Z Tabi, M P Pende. Apoptosis of V beta 8.2+ T lymphocytes in the spinal cord during recovery from experimental autoimmune encephalomyelitis induced in Lewis rats by inoculation with myelin basic protein. Journal of the neurological sciences. vol 139. issue 1. 1996-12-23. PMID:8836965. |
from day 14 onwards, there was selective enrichment of v beta 8.2+ cells in the apoptotic population, and the percentage of v beta 8.2+ cells undergoing apoptosis was greater than the percentages of cd5+ and tcr alpha beta + cells undergoing apoptosis. |
1996-12-23 |
2023-08-12 |
rat |
| A Kaipia, S Y Chun, K Eisenhauer, A J Hsue. Tumor necrosis factor-alpha and its second messenger, ceramide, stimulate apoptosis in cultured ovarian follicles. Endocrinology. vol 137. issue 11. 1996-12-17. PMID:8895358. |
tumor necrosis factor-alpha (tnf alpha) is a cytokine capable of inducing apoptosis in diverse cell types, and the apoptotic effect of tnf alpha is, partially, coupled to the sphingomyelin signaling pathway with ceramide as a second messenger. |
1996-12-17 |
2023-08-12 |
rat |
| A Kaipia, S Y Chun, K Eisenhauer, A J Hsue. Tumor necrosis factor-alpha and its second messenger, ceramide, stimulate apoptosis in cultured ovarian follicles. Endocrinology. vol 137. issue 11. 1996-12-17. PMID:8895358. |
because tnf alpha has been localized in the rat ovary, and tnf alpha treatment increases granulosa cell ceramide production, we studied the effect of treatment with tnf alpha and ceramide on follicle apoptosis. |
1996-12-17 |
2023-08-12 |
rat |
| A Kaipia, S Y Chun, K Eisenhauer, A J Hsue. Tumor necrosis factor-alpha and its second messenger, ceramide, stimulate apoptosis in cultured ovarian follicles. Endocrinology. vol 137. issue 11. 1996-12-17. PMID:8895358. |
to study the mechanism of tnf alpha and ceramide action, the effect of sodium aurathiomalate (atm), an inhibitor of interleukin-1 beta-converting enzyme/ced-3-related cystine proteases known to be essential in the execution of mammalian cell apoptosis, was studied. |
1996-12-17 |
2023-08-12 |
rat |
| A Kaipia, S Y Chun, K Eisenhauer, A J Hsue. Tumor necrosis factor-alpha and its second messenger, ceramide, stimulate apoptosis in cultured ovarian follicles. Endocrinology. vol 137. issue 11. 1996-12-17. PMID:8895358. |
treatment with atm (1 mm) prevented the apoptosis-inducing effect of both tnf alpha and ceramide, suggesting a role for cysteine proteases in mediating follicle apoptosis. |
1996-12-17 |
2023-08-12 |
rat |
| A Kaipia, S Y Chun, K Eisenhauer, A J Hsue. Tumor necrosis factor-alpha and its second messenger, ceramide, stimulate apoptosis in cultured ovarian follicles. Endocrinology. vol 137. issue 11. 1996-12-17. PMID:8895358. |
in summary, treatment with tnf alpha or its second messenger, ceramide, stimulates apoptosis of early antral follicles in culture, suggesting a potential role for tnf alpha as an intraovarian regulator of follicle atresia by acting through the ceramide signaling pathway. |
1996-12-17 |
2023-08-12 |
rat |
| D J Van Antwerp, S J Martin, T Kafri, D R Green, I M Verm. Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science (New York, N.Y.). vol 274. issue 5288. 1996-12-10. PMID:8864120. |
tumor necrosis factor alpha (tnf-alpha) signaling gives rise to a number of events, including activation of transcription factor nf-kappab and programmed cell death (apoptosis). |
1996-12-10 |
2023-08-12 |
Not clear |