Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
G Zauli, M Vitale, E Falcieri, D Gibellini, A Bassini, C Celeghini, M Columbaro, S Capitan. In vitro senescence and apoptotic cell death of human megakaryocytes. Blood. vol 90. issue 6. 1997-10-20. PMID:9310474. |
the addition of tpo but not interleukin-3 or erythropoietin showed some protection of alpha(iib)beta3+ cells from apoptosis at early culture times (days 2 to 4), but it did not show any significant effect at later time points. |
1997-10-20 |
2023-08-12 |
human |
U Giambarella, T Yamatsuji, T Okamoto, T Matsui, T Ikezu, Y Murayama, M A Levine, A Katz, N Gautam, I Nishimot. G protein betagamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP. The EMBO journal. vol 16. issue 16. 1997-10-17. PMID:9305632. |
expression of these mutants causes a cos cell nk1 clone to undergo pertussis toxin-sensitive apoptosis in an fad trait-linked manner by activating the g protein go, which consists of g alpha(o) and g betagamma subunits. |
1997-10-17 |
2023-08-12 |
Not clear |
U Giambarella, T Yamatsuji, T Okamoto, T Matsui, T Ikezu, Y Murayama, M A Levine, A Katz, N Gautam, I Nishimot. G protein betagamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP. The EMBO journal. vol 16. issue 16. 1997-10-17. PMID:9305632. |
in the same system, expression of mutationally activated g alpha(o) or g alpha(i) induced little apoptosis. |
1997-10-17 |
2023-08-12 |
Not clear |
H Tanak. [Interferon]. Gan to kagaku ryoho. Cancer & chemotherapy. vol 24. issue 11. 1997-10-17. PMID:9309144. |
the pkr phosphorylate eif2 alpha that leads to blocking of protein synthesis, mediates signal transduction via nf-kappa b and/or probably irf-1, and is also involved in apoptosis. |
1997-10-17 |
2023-08-12 |
mouse |
W J Murdoch, D C Colgin, J A Elli. Role of tumor necrosis factor-alpha in the ovulatory mechanism of ewes. Journal of animal science. vol 75. issue 6. 1997-10-15. PMID:9250523. |
finally, tnf alpha induced ovarian cell apoptosis in vitro. |
1997-10-15 |
2023-08-12 |
Not clear |
P Garside, W A Sands, J R Kusel, P Haga. Is the induction of apoptosis the mechanism of the protective effects of TNF alpha in helminth infection? Parasite immunology. vol 18. issue 3. 1997-09-30. PMID:9223164. |
is the induction of apoptosis the mechanism of the protective effects of tnf alpha in helminth infection? |
1997-09-30 |
2023-08-12 |
Not clear |
P Garside, W A Sands, J R Kusel, P Haga. Is the induction of apoptosis the mechanism of the protective effects of TNF alpha in helminth infection? Parasite immunology. vol 18. issue 3. 1997-09-30. PMID:9223164. |
here we suggest that, by employing phylogenetically conserved mechanisms, the mammalian immune system is able to interfere with helminth development directly and that the protective effects of tnf alpha in helminth infections may operate via the induction of parasite apoptosis. |
1997-09-30 |
2023-08-12 |
Not clear |
G Melino, M Draoui, L Bellincampi, F Bernassola, S Bernardini, M Piacentini, U Reichert, P Cohe. Retinoic acid receptors alpha and gamma mediate the induction of "tissue" transglutaminase activity and apoptosis in human neuroblastoma cells. Experimental cell research. vol 235. issue 1. 1997-09-30. PMID:9281352. |
retinoic acid receptors alpha and gamma mediate the induction of "tissue" transglutaminase activity and apoptosis in human neuroblastoma cells. |
1997-09-30 |
2023-08-12 |
human |
R Kettritz, R J Falk, J C Jennette, M L Gaid. Neutrophil superoxide release is required for spontaneous and FMLP-mediated but not for TNF alpha-mediated apoptosis. Journal of the American Society of Nephrology : JASN. vol 8. issue 7. 1997-09-24. PMID:9219158. |
pmn apoptosis was detected by dna fragmentation, and ultraviolet and light microscopy, and was quantified by flow cytometry; superoxide release was measured by superoxide dismutase-inhibitable reduction of ferricytochrome c. incubation of pmn with 20 ng/ml tumor necrosis factor (tnf)alpha induced superoxide release (8.8 +/- 7.5 nmol o2-/30 min, n = 7) in normal pmn and also resulted in apoptosis within 2 h, whereas a subactivating dose of 2 ng/ml tnf alpha, which did not trigger superoxide release (3.1 +/- 1.7 nmol o2-, n = 10), did facilitate apoptosis, although to a lesser degree. |
1997-09-24 |
2023-08-12 |
Not clear |
R Kettritz, R J Falk, J C Jennette, M L Gaid. Neutrophil superoxide release is required for spontaneous and FMLP-mediated but not for TNF alpha-mediated apoptosis. Journal of the American Society of Nephrology : JASN. vol 8. issue 7. 1997-09-24. PMID:9219158. |
pmn cultured under nonstimulating conditions underwent apoptotic cell death after 8 h. exogenous superoxide dismutase did not inhibit apoptosis induced by 20 ng/ml tnf alpha. |
1997-09-24 |
2023-08-12 |
Not clear |
L Benassi, D Ottani, F Fantini, A Marconi, C Chiodino, A Giannetti, C Pincell. 1,25-dihydroxyvitamin D3, transforming growth factor beta1, calcium, and ultraviolet B radiation induce apoptosis in cultured human keratinocytes. The Journal of investigative dermatology. vol 109. issue 3. 1997-09-24. PMID:9284090. |
apoptosis was analyzed after stimulation with 1,25-dihydroxyvitamin d3 [1,25(oh)2d3], transforming growth factor beta1 (tgfbeta1), calcium, uvb, or tumor necrosis factor alpha (tnfalpha). |
1997-09-24 |
2023-08-12 |
human |
V Dangles, F Féménia, V Lainé, M Berthelemy, D Le Rhun, M F Poupon, D Levy, I Schwartz-Corni. Two- and three-dimensional cell structures govern epidermal growth factor survival function in human bladder carcinoma cell lines. Cancer research. vol 57. issue 16. 1997-09-09. PMID:9269996. |
conversely, egf and transforming growth factor alpha prevented apoptosis when the same serum-starved cells were cultured as three-dimensional spheroids. |
1997-09-09 |
2023-08-12 |
human |
P N Huynh, R M Lori. Contrasting effects of alpha- and beta-androstenediol on oncogenic myeloid cell lines in vitro. Journal of leukocyte biology. vol 62. issue 2. 1997-09-04. PMID:9261340. |
at 50 nm or above, 17 alpha aed induced apoptosis in raw cells and hl-60 as detected by transmission electron microscopy and tunel assays. |
1997-09-04 |
2023-08-12 |
human |
J Gómez, C Martínez, B Fernández, A García, A Reboll. Ras activation leads to cell proliferation or apoptotic cell death upon interleukin-2 stimulation or lymphokine deprivation, respectively. European journal of immunology. vol 27. issue 7. 1997-08-25. PMID:9247568. |
we describe that lymphokine deprivation of the interleukin (il)-2- or il-4-dependent mouse t cell line ts1 alpha beta induces ras activation which plays a role in programmed cell death, since blocking ras activity reduces the induction of apoptosis. |
1997-08-25 |
2023-08-12 |
mouse |
J E Saavedra, T R Billiar, D L Williams, Y M Kim, S C Watkins, L K Keefe. Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liver. Journal of medicinal chemistry. vol 40. issue 13. 1997-08-07. PMID:9207935. |
of five cell types examined, only cultured hepatocytes metabolized o2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (v-pyrro/no) to no, triggering cyclic guanosine 3',5'-monophosphate (cgmp) synthesis and protecting the hepatocytes from apoptotic cell death induced by treatment with tumor necrosis factor-alpha (tnf alpha) plus actinomycin d. in vivo, v-pyrro/no increased liver cgmp levels while minimally affecting systemic hemodynamics, protecting rats dosed with tnf alpha plus galactosamine from apoptosis and hepatotoxicity. |
1997-08-07 |
2023-08-12 |
rat |
D R Brison, R M Schult. Apoptosis during mouse blastocyst formation: evidence for a role for survival factors including transforming growth factor alpha. Biology of reproduction. vol 56. issue 5. 1997-07-28. PMID:9160705. |
apoptosis during mouse blastocyst formation: evidence for a role for survival factors including transforming growth factor alpha. |
1997-07-28 |
2023-08-12 |
mouse |
C A Baumann, M Badamchian, A L Goldstei. Thymosin alpha 1 antagonizes dexamethasone and CD3-induced apoptosis of CD4+ CD8+ thymocytes through the activation of cAMP and protein kinase C dependent second messenger pathways. Mechanisms of ageing and development. vol 94. issue 1-3. 1997-07-23. PMID:9147362. |
thymosin alpha 1 antagonizes dexamethasone and cd3-induced apoptosis of cd4+ cd8+ thymocytes through the activation of camp and protein kinase c dependent second messenger pathways. |
1997-07-23 |
2023-08-12 |
Not clear |
C A Baumann, M Badamchian, A L Goldstei. Thymosin alpha 1 antagonizes dexamethasone and CD3-induced apoptosis of CD4+ CD8+ thymocytes through the activation of cAMP and protein kinase C dependent second messenger pathways. Mechanisms of ageing and development. vol 94. issue 1-3. 1997-07-23. PMID:9147362. |
t alpha 1 treatment of thymocytes delays the production of free radicals and the subsequent consumption of glutathione, that is observed during both dex and cd3 induced apoptosis. |
1997-07-23 |
2023-08-12 |
Not clear |
C A Baumann, M Badamchian, A L Goldstei. Thymosin alpha 1 antagonizes dexamethasone and CD3-induced apoptosis of CD4+ CD8+ thymocytes through the activation of cAMP and protein kinase C dependent second messenger pathways. Mechanisms of ageing and development. vol 94. issue 1-3. 1997-07-23. PMID:9147362. |
these data suggest that t alpha 1 exerts an influence on the development of a population of immature t-cells in the thymus by effecting the sensitivity of thymocytes to apoptosis during the pre-selection stages of thymic development. |
1997-07-23 |
2023-08-12 |
Not clear |
A Schwarz, K Mahnke, T A Luger, T Schwar. Pentoxifylline reduces the formation of sunburn cells. Experimental dermatology. vol 6. issue 1. 1997-07-18. PMID:9067700. |
recently, it was demonstrated that tumor necrosis factor alpha (tnf alpha) appears to be involved in the formation of sc since neutralization of tnf alpha both in vitro and in vivo reduced uvb-induced apoptosis of keratinocytes. |
1997-07-18 |
2023-08-12 |
mouse |