Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
X Chen, J Wang, B Fu, L Y. RGD-containing peptides trigger apoptosis in glomerular mesangial cells of adult human kidneys. Biochemical and biophysical research communications. vol 234. issue 3. 1997-06-30. PMID:9175758. |
substantial evidence was given that different arg-gly-asp (rgd)-containing peptides, linear arg-gly-asp-ser (rgds) and cyclic arg-gly-asp-phe (rgdf), which are sequences present in fibronectin and vitronectin and which can bind alpha5beta1 and alpha(v)beta3 integrins, respectively, both induced apoptosis and expression of interleukin-1beta-converting enzyme (ice) in cultured glomerular mesangial cells from adult human kidneys, with consistent apoptosis features appearing as nuclei condensation and fragmentation, internucleosomal dna fragmentation, and dna content decrease. |
1997-06-30 |
2023-08-12 |
human |
G Visani, D Russo, E Ottaviani, P Tosi, D Damiani, A Michelutti, S Manfroi, M Baccarani, S Tur. Effects of homoharringtonine alone and in combination with alpha interferon and cytosine arabinoside on 'in vitro' growth and induction of apoptosis in chronic myeloid leukemia and normal hematopoietic progenitors. Leukemia. vol 11. issue 5. 1997-06-26. PMID:9180282. |
effects of homoharringtonine alone and in combination with alpha interferon and cytosine arabinoside on 'in vitro' growth and induction of apoptosis in chronic myeloid leukemia and normal hematopoietic progenitors. |
1997-06-26 |
2023-08-12 |
Not clear |
O Ebert, S Finke, A Salahi, M Herrmann, B Trojaneck, P Lefterova, E Wagner, R Kircheis, D Huhn, F Schriever, I G Schmidt-Wol. Lymphocyte apoptosis: induction by gene transfer techniques. Gene therapy. vol 4. issue 4. 1997-06-23. PMID:9176514. |
since apoptosis may be mediated via the tnf alpha and tnf alpha receptor pathway, we studied the amount of tnf secreted by transfected lymphocytes. |
1997-06-23 |
2023-08-12 |
Not clear |
T Mainou-Fowler, A G Prentic. Modulation of apoptosis with cytokines in B-cell chronic lymphocytic leukaemia. Leukemia & lymphoma. vol 21. issue 5-6. 1997-06-05. PMID:9172801. |
interleukin 4 protects b-cll b cells from il5-, anti(alpha) apo-1- and steroid-induced apoptosis. |
1997-06-05 |
2023-08-12 |
Not clear |
M P Nair, S A Schwartz, R Polasani, J Hou, A Sweet, K C Chadh. Immunoregulatory effects of morphine on human lymphocytes. Clinical and diagnostic laboratory immunology. vol 4. issue 2. 1997-06-03. PMID:9067644. |
the present study was undertaken to examine the immunomodulatory role of morphine on hiv protein-induced lymphocyte proliferative responses, sendai and newcastle disease virus-induced alpha ifn (ifn-alpha) and ifn-beta production by lymphocytes and fibroblast cells, respectively, and induction of apoptosis of normal lymphocytes in vitro. |
1997-06-03 |
2023-08-12 |
human |
G Q Chen, X G Shi, W Tang, S M Xiong, J Zhu, X Cai, Z G Han, J H Ni, G Y Shi, P M Jia, M M Liu, K L He, C Niu, J Ma, P Zhang, T D Zhang, P Paul, T Naoe, K Kitamura, W Miller, S Waxman, Z Y Wang, H de The, S J Chen, Z Che. Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. Blood. vol 89. issue 9. 1997-06-03. PMID:9129041. |
we found previously that as2o3 can trigger apoptosis of apl cell line nb4 cells, which is associated with downregulation of bcl-2 gene expression and modulation of pml-rar alpha chimeric protein. |
1997-06-03 |
2023-08-12 |
Not clear |
G Q Chen, X G Shi, W Tang, S M Xiong, J Zhu, X Cai, Z G Han, J H Ni, G Y Shi, P M Jia, M M Liu, K L He, C Niu, J Ma, P Zhang, T D Zhang, P Paul, T Naoe, K Kitamura, W Miller, S Waxman, Z Y Wang, H de The, S J Chen, Z Che. Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. Blood. vol 89. issue 9. 1997-06-03. PMID:9129041. |
in conclusion, combination of induction of apoptosis and partial differention could be the main cellular mechanisms of as2o3 in the treatment of apl, and pml-rar alpha could play an important role in determining the specific effects of as2o3 on apl cells. |
1997-06-03 |
2023-08-12 |
Not clear |
A Foghi, K J Teerds, H van der Donk, J Dorringto. Induction of apoptosis in rat thecal/interstitial cells by transforming growth factor alpha plus transforming growth factor beta in vitro. The Journal of endocrinology. vol 153. issue 1. 1997-05-19. PMID:9135581. |
induction of apoptosis in rat thecal/interstitial cells by transforming growth factor alpha plus transforming growth factor beta in vitro. |
1997-05-19 |
2023-08-12 |
rat |
A Foghi, K J Teerds, H van der Donk, J Dorringto. Induction of apoptosis in rat thecal/interstitial cells by transforming growth factor alpha plus transforming growth factor beta in vitro. The Journal of endocrinology. vol 153. issue 1. 1997-05-19. PMID:9135581. |
chromatin condensation and internucleosomal fragmentation, characteristic of apoptosis, were observed by nucleic acid staining and fluorescence microscopy of thecal/interstitial cells treated with tgf alpha plus tgf beta 1. |
1997-05-19 |
2023-08-12 |
rat |
A Foghi, K J Teerds, H van der Donk, J Dorringto. Induction of apoptosis in rat thecal/interstitial cells by transforming growth factor alpha plus transforming growth factor beta in vitro. The Journal of endocrinology. vol 153. issue 1. 1997-05-19. PMID:9135581. |
this response of thecal/interstitial cells to tgf alpha plus tgf beta 1 was density dependent; confluent cultures were protected from the induction of apoptosis under these conditions. |
1997-05-19 |
2023-08-12 |
rat |
P O Iversen, T R Hercus, B Zacharakis, J M Woodcock, F C Stomski, S Kumar, B H Nelson, A Miyajima, A F Lope. The apoptosis-inducing granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R functions through specific regions of the heterodimeric GM-CSF receptor and requires interleukin-1beta-converting enzyme-like proteases. The Journal of biological chemistry. vol 272. issue 15. 1997-05-15. PMID:9092524. |
specifically, the 16 membrane-proximal residues of the alpha subunit were sufficient for apoptosis. |
1997-05-15 |
2023-08-12 |
Not clear |
P O Iversen, T R Hercus, B Zacharakis, J M Woodcock, F C Stomski, S Kumar, B H Nelson, A Miyajima, A F Lope. The apoptosis-inducing granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R functions through specific regions of the heterodimeric GM-CSF receptor and requires interleukin-1beta-converting enzyme-like proteases. The Journal of biological chemistry. vol 272. issue 15. 1997-05-15. PMID:9092524. |
cells expressing the alpha subunit and truncated betac mutants showed that the 96 membrane-proximal residues of betac were sufficient for apoptosis. |
1997-05-15 |
2023-08-12 |
Not clear |
L Van Parijs, A Biuckians, A Ibragimov, F W Alt, D M Willerford, A K Abba. Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 8. 1997-05-05. PMID:9103438. |
functional responses and apoptosis of cd25 (il-2r alpha)-deficient t cells expressing a transgenic antigen receptor. |
1997-05-05 |
2023-08-12 |
mouse |
P Hofmann, H Sprenger, A Kaufmann, A Bender, C Hasse, M Nain, D Gems. Susceptibility of mononuclear phagocytes to influenza A virus infection and possible role in the antiviral response. Journal of leukocyte biology. vol 61. issue 4. 1997-05-02. PMID:9103226. |
after infection, de novo viral protein synthesis was initiated but then interrupted after 4-6 h. most macrophages died by apoptosis within 25-30 h. before cell death, however, macrophages responded to influenza a virus with a high cytokine gene transcription and subsequent release of tumor necrosis factor alpha (tnf-alpha), interleukin-1 (il-1), il-6, interferon (ifn)-alpha/beta, and cc-chemokines. |
1997-05-02 |
2023-08-12 |
Not clear |
G M Renshaw, R Goldi. Neuronal bungarotoxin displaces (125I) alpha-bungarotoxin binding at the neuromuscular junction as well as to the spinal cord during embryogenesis. Brain research. vol 709. issue 2. 1997-05-01. PMID:8833769. |
alpha-bungarotoxin (alpha btx) administration in ovo prevents motoneuron apoptosis during development. |
1997-05-01 |
2023-08-12 |
chicken |
I Kitajima, T Nakajima, T Imamura, I Takasaki, K Kawahara, T Okano, T Tokioka, Y Soejima, K Abeyama, I Maruyam. Induction of apoptosis in murine clonal osteoblasts expressed by human T-cell leukemia virus type I tax by NF-kappa B and TNF-alpha. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 11. issue 2. 1997-04-29. PMID:8822344. |
this apoptosis was prevented by treatment with neutralizing anti-tnf-alpha antibody (alpha tnf). |
1997-04-29 |
2023-08-12 |
human |
G F Kalf, J F Renz, R Niculesc. p-Benzoquinone, a reactive metabolite of benzene, prevents the processing of pre-interleukins-1 alpha and -1 beta to active cytokines by inhibition of the processing enzymes, calpain, and interleukin-1 beta converting enzyme. Environmental health perspectives. vol 104 Suppl 6. 1997-04-18. PMID:9118901. |
thus benzene-induced bone marrow hypocellularity may result from apoptosis of hematopoietic progenitor cells brought about by lack of essential cytokines and deficient il-1 alpha production subsequent to the inhibition of calpain by p-benzoquinone and the prevention of pre-il-1 processing. |
1997-04-18 |
2023-08-12 |
mouse |
S J Chmura, E Nodzenski, M A Beckett, D W Kufe, J Quintans, R R Weichselbau. Loss of ceramide production confers resistance to radiation-induced apoptosis. Cancer research. vol 57. issue 7. 1997-04-17. PMID:9102212. |
both neutral and acidic sphingomyelinases, which generate the lipid second messenger ceramide, are reported to induce apoptosis following ionizing radiation and other death signals such as tumor necrosis factor alpha and fas ligand. |
1997-04-17 |
2023-08-12 |
Not clear |
J M Chandler, E S Alnemri, G M Cohen, M MacFarlan. Activation of CPP32 and Mch3 alpha in wild-type p53-induced apoptosis. The Biochemical journal. vol 322 ( Pt 1). 1997-04-15. PMID:9078237. |
activation of cpp32 and mch3 alpha in wild-type p53-induced apoptosis. |
1997-04-15 |
2023-08-12 |
Not clear |
M Kawanish. Epstein-Barr virus BHRF1 protein protects intestine 407 epithelial cells from apoptosis induced by tumor necrosis factor alpha and anti-Fas antibody. Journal of virology. vol 71. issue 4. 1997-04-11. PMID:9060702. |
epstein-barr virus bhrf1 protein protects intestine 407 epithelial cells from apoptosis induced by tumor necrosis factor alpha and anti-fas antibody. |
1997-04-11 |
2023-08-12 |
Not clear |