| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Miscia, A Di Baldassarre, A Catald. Shift of DNA polymerase alpha nuclear distribution and activity in apoptotic human leukaemia cells. Biochemical and biophysical research communications. vol 234. issue 2. 1997-07-10. PMID:9177264. |
taken together, these results suggest that among the intracellular processes elicited by mtx-induced apoptosis in hl60 cells, the redistribution of dna polymerase alpha and the stimulation of dna polymerase beta activity might represent an extreme attempt of the cell to preserve the replicative machinery during fragmentation and chromatin margination. |
1997-07-10 |
2023-08-12 |
human |
| G S Salomons, H J Brady, M Verwijs-Janssen, J D Van Den Berg, A A Hart, H Van Den Berg, H Behrendt, K Hählen, L A Smet. The Bax alpha:Bcl-2 ratio modulates the response to dexamethasone in leukaemic cells and is highly variable in childhood acute leukaemia. International journal of cancer. vol 71. issue 6. 1997-07-08. PMID:9185697. |
bcl-2 over-expression has been shown to inhibit apoptosis induced by a variety of stimuli, whereas a predominance of bax alpha to bcl-2 accelerates apoptosis upon apoptotic stimuli. |
1997-07-08 |
2023-08-12 |
Not clear |
| G S Salomons, H J Brady, M Verwijs-Janssen, J D Van Den Berg, A A Hart, H Van Den Berg, H Behrendt, K Hählen, L A Smet. The Bax alpha:Bcl-2 ratio modulates the response to dexamethasone in leukaemic cells and is highly variable in childhood acute leukaemia. International journal of cancer. vol 71. issue 6. 1997-07-08. PMID:9185697. |
results suggest that bax alpha:bcl-2, rather than bcl-2 alone is important for the survival of drug-induced apoptosis in leukemic cell lines and all. |
1997-07-08 |
2023-08-12 |
Not clear |
| M Wallén-Ohman, J W Larrick, R Carlsson, C A Borrebaec. Ligation of MHC class I induces apoptosis in human pre-B cell lines, in promyelocytic cell lines and in CD40-stimulated mature B cells. International immunology. vol 9. issue 4. 1997-07-01. PMID:9138021. |
the apoptotic response was not dependent on the epitope specificity, since other anti-mhc-i antibodies, reacting with different monomorphic determinants of the alpha chain or beta 2-microglobulin, also induced apoptosis in these cells. |
1997-07-01 |
2023-08-12 |
human |
| X Chen, J Wang, B Fu, L Y. RGD-containing peptides trigger apoptosis in glomerular mesangial cells of adult human kidneys. Biochemical and biophysical research communications. vol 234. issue 3. 1997-06-30. PMID:9175758. |
substantial evidence was given that different arg-gly-asp (rgd)-containing peptides, linear arg-gly-asp-ser (rgds) and cyclic arg-gly-asp-phe (rgdf), which are sequences present in fibronectin and vitronectin and which can bind alpha5beta1 and alpha(v)beta3 integrins, respectively, both induced apoptosis and expression of interleukin-1beta-converting enzyme (ice) in cultured glomerular mesangial cells from adult human kidneys, with consistent apoptosis features appearing as nuclei condensation and fragmentation, internucleosomal dna fragmentation, and dna content decrease. |
1997-06-30 |
2023-08-12 |
human |
| G Visani, D Russo, E Ottaviani, P Tosi, D Damiani, A Michelutti, S Manfroi, M Baccarani, S Tur. Effects of homoharringtonine alone and in combination with alpha interferon and cytosine arabinoside on 'in vitro' growth and induction of apoptosis in chronic myeloid leukemia and normal hematopoietic progenitors. Leukemia. vol 11. issue 5. 1997-06-26. PMID:9180282. |
effects of homoharringtonine alone and in combination with alpha interferon and cytosine arabinoside on 'in vitro' growth and induction of apoptosis in chronic myeloid leukemia and normal hematopoietic progenitors. |
1997-06-26 |
2023-08-12 |
Not clear |
| O Ebert, S Finke, A Salahi, M Herrmann, B Trojaneck, P Lefterova, E Wagner, R Kircheis, D Huhn, F Schriever, I G Schmidt-Wol. Lymphocyte apoptosis: induction by gene transfer techniques. Gene therapy. vol 4. issue 4. 1997-06-23. PMID:9176514. |
since apoptosis may be mediated via the tnf alpha and tnf alpha receptor pathway, we studied the amount of tnf secreted by transfected lymphocytes. |
1997-06-23 |
2023-08-12 |
Not clear |
| T Mainou-Fowler, A G Prentic. Modulation of apoptosis with cytokines in B-cell chronic lymphocytic leukaemia. Leukemia & lymphoma. vol 21. issue 5-6. 1997-06-05. PMID:9172801. |
interleukin 4 protects b-cll b cells from il5-, anti(alpha) apo-1- and steroid-induced apoptosis. |
1997-06-05 |
2023-08-12 |
Not clear |
| M P Nair, S A Schwartz, R Polasani, J Hou, A Sweet, K C Chadh. Immunoregulatory effects of morphine on human lymphocytes. Clinical and diagnostic laboratory immunology. vol 4. issue 2. 1997-06-03. PMID:9067644. |
the present study was undertaken to examine the immunomodulatory role of morphine on hiv protein-induced lymphocyte proliferative responses, sendai and newcastle disease virus-induced alpha ifn (ifn-alpha) and ifn-beta production by lymphocytes and fibroblast cells, respectively, and induction of apoptosis of normal lymphocytes in vitro. |
1997-06-03 |
2023-08-12 |
human |
| G Q Chen, X G Shi, W Tang, S M Xiong, J Zhu, X Cai, Z G Han, J H Ni, G Y Shi, P M Jia, M M Liu, K L He, C Niu, J Ma, P Zhang, T D Zhang, P Paul, T Naoe, K Kitamura, W Miller, S Waxman, Z Y Wang, H de The, S J Chen, Z Che. Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. Blood. vol 89. issue 9. 1997-06-03. PMID:9129041. |
we found previously that as2o3 can trigger apoptosis of apl cell line nb4 cells, which is associated with downregulation of bcl-2 gene expression and modulation of pml-rar alpha chimeric protein. |
1997-06-03 |
2023-08-12 |
Not clear |
| G Q Chen, X G Shi, W Tang, S M Xiong, J Zhu, X Cai, Z G Han, J H Ni, G Y Shi, P M Jia, M M Liu, K L He, C Niu, J Ma, P Zhang, T D Zhang, P Paul, T Naoe, K Kitamura, W Miller, S Waxman, Z Y Wang, H de The, S J Chen, Z Che. Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells. Blood. vol 89. issue 9. 1997-06-03. PMID:9129041. |
in conclusion, combination of induction of apoptosis and partial differention could be the main cellular mechanisms of as2o3 in the treatment of apl, and pml-rar alpha could play an important role in determining the specific effects of as2o3 on apl cells. |
1997-06-03 |
2023-08-12 |
Not clear |
| A Foghi, K J Teerds, H van der Donk, J Dorringto. Induction of apoptosis in rat thecal/interstitial cells by transforming growth factor alpha plus transforming growth factor beta in vitro. The Journal of endocrinology. vol 153. issue 1. 1997-05-19. PMID:9135581. |
induction of apoptosis in rat thecal/interstitial cells by transforming growth factor alpha plus transforming growth factor beta in vitro. |
1997-05-19 |
2023-08-12 |
rat |
| A Foghi, K J Teerds, H van der Donk, J Dorringto. Induction of apoptosis in rat thecal/interstitial cells by transforming growth factor alpha plus transforming growth factor beta in vitro. The Journal of endocrinology. vol 153. issue 1. 1997-05-19. PMID:9135581. |
chromatin condensation and internucleosomal fragmentation, characteristic of apoptosis, were observed by nucleic acid staining and fluorescence microscopy of thecal/interstitial cells treated with tgf alpha plus tgf beta 1. |
1997-05-19 |
2023-08-12 |
rat |
| A Foghi, K J Teerds, H van der Donk, J Dorringto. Induction of apoptosis in rat thecal/interstitial cells by transforming growth factor alpha plus transforming growth factor beta in vitro. The Journal of endocrinology. vol 153. issue 1. 1997-05-19. PMID:9135581. |
this response of thecal/interstitial cells to tgf alpha plus tgf beta 1 was density dependent; confluent cultures were protected from the induction of apoptosis under these conditions. |
1997-05-19 |
2023-08-12 |
rat |
| P O Iversen, T R Hercus, B Zacharakis, J M Woodcock, F C Stomski, S Kumar, B H Nelson, A Miyajima, A F Lope. The apoptosis-inducing granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R functions through specific regions of the heterodimeric GM-CSF receptor and requires interleukin-1beta-converting enzyme-like proteases. The Journal of biological chemistry. vol 272. issue 15. 1997-05-15. PMID:9092524. |
specifically, the 16 membrane-proximal residues of the alpha subunit were sufficient for apoptosis. |
1997-05-15 |
2023-08-12 |
Not clear |
| P O Iversen, T R Hercus, B Zacharakis, J M Woodcock, F C Stomski, S Kumar, B H Nelson, A Miyajima, A F Lope. The apoptosis-inducing granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R functions through specific regions of the heterodimeric GM-CSF receptor and requires interleukin-1beta-converting enzyme-like proteases. The Journal of biological chemistry. vol 272. issue 15. 1997-05-15. PMID:9092524. |
cells expressing the alpha subunit and truncated betac mutants showed that the 96 membrane-proximal residues of betac were sufficient for apoptosis. |
1997-05-15 |
2023-08-12 |
Not clear |
| L Van Parijs, A Biuckians, A Ibragimov, F W Alt, D M Willerford, A K Abba. Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor. Journal of immunology (Baltimore, Md. : 1950). vol 158. issue 8. 1997-05-05. PMID:9103438. |
functional responses and apoptosis of cd25 (il-2r alpha)-deficient t cells expressing a transgenic antigen receptor. |
1997-05-05 |
2023-08-12 |
mouse |
| P Hofmann, H Sprenger, A Kaufmann, A Bender, C Hasse, M Nain, D Gems. Susceptibility of mononuclear phagocytes to influenza A virus infection and possible role in the antiviral response. Journal of leukocyte biology. vol 61. issue 4. 1997-05-02. PMID:9103226. |
after infection, de novo viral protein synthesis was initiated but then interrupted after 4-6 h. most macrophages died by apoptosis within 25-30 h. before cell death, however, macrophages responded to influenza a virus with a high cytokine gene transcription and subsequent release of tumor necrosis factor alpha (tnf-alpha), interleukin-1 (il-1), il-6, interferon (ifn)-alpha/beta, and cc-chemokines. |
1997-05-02 |
2023-08-12 |
Not clear |
| G M Renshaw, R Goldi. Neuronal bungarotoxin displaces (125I) alpha-bungarotoxin binding at the neuromuscular junction as well as to the spinal cord during embryogenesis. Brain research. vol 709. issue 2. 1997-05-01. PMID:8833769. |
alpha-bungarotoxin (alpha btx) administration in ovo prevents motoneuron apoptosis during development. |
1997-05-01 |
2023-08-12 |
chicken |
| I Kitajima, T Nakajima, T Imamura, I Takasaki, K Kawahara, T Okano, T Tokioka, Y Soejima, K Abeyama, I Maruyam. Induction of apoptosis in murine clonal osteoblasts expressed by human T-cell leukemia virus type I tax by NF-kappa B and TNF-alpha. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 11. issue 2. 1997-04-29. PMID:8822344. |
this apoptosis was prevented by treatment with neutralizing anti-tnf-alpha antibody (alpha tnf). |
1997-04-29 |
2023-08-12 |
human |