| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tae Woo Jung, Sung Tae Kim, Jun Ho Lee, Soo In Chae, Kwang Woo Hwang, Yoon Hee Chung, Hyoung-Chun Kim, A M Abd El-Aty, Tae Jin Lee, Eon Sub Park, Ji Hoon Jeon. Phosphatidylcholine Causes Lipolysis and Apoptosis in Adipocytes through the Tumor Necrosis Factor Alpha-Dependent Pathway. Pharmacology. vol 101. issue 3-4. 2018-08-29. PMID:29186713. |
in this study, we demonstrated that ppc induces lipolysis and apoptosis in adipocytes, and evaluated a possible tumor necrosis factor alpha (tnfα)-dependent pathway, whereby ppc exerts these effects. |
2018-08-29 |
2023-08-13 |
mouse |
| He Zhu, Jianshuai He, Jia Liu, Xin Zhang, Fengyun Yang, Pingting Liu, Shilei Wan. Alpha 1-antitrypsin ameliorates ventilator-induced lung injury in rats by inhibiting inflammatory responses and apoptosis. Experimental biology and medicine (Maywood, N.J.). vol 243. issue 1. 2018-08-17. PMID:29096562. |
alpha 1-antitrypsin ameliorates ventilator-induced lung injury in rats by inhibiting inflammatory responses and apoptosis. |
2018-08-17 |
2023-08-13 |
rat |
| Masumeh Sanaei, Fraidoon Kavoosi, Habibeh Saleh. Genistein and Trichostatin A Induction of Estrogen Receptor Alpha Gene Expression, Apoptosis and Cell Growth Inhibition in Hepatocellular Carcinoma HepG 2 Cells Asian Pacific journal of cancer prevention : APJCP. vol 18. issue 12. 2018-08-14. PMID:29286617. |
genistein and trichostatin a induction of estrogen receptor alpha gene expression, apoptosis and cell growth inhibition in hepatocellular carcinoma hepg 2 cells epigenetic changes such as dna methylation and histone acetylation play important roles in determining geneexpression. |
2018-08-14 |
2023-08-13 |
Not clear |
| Masumeh Sanaei, Fraidoon Kavoosi, Habibeh Saleh. Genistein and Trichostatin A Induction of Estrogen Receptor Alpha Gene Expression, Apoptosis and Cell Growth Inhibition in Hepatocellular Carcinoma HepG 2 Cells Asian Pacific journal of cancer prevention : APJCP. vol 18. issue 12. 2018-08-14. PMID:29286617. |
dna demethylating agents such as genistein (ge) and histone deacetylase inhibitors (hdacis) such astrichostatin a (tsa) may strongly reactivate silenced genes and exposure to these two agents in combination is reportedto enhance estrogen receptor alpha (erα) reactivation and induction of apoptosis. |
2018-08-14 |
2023-08-13 |
Not clear |
| Riya Ganguly, Devin Hasanally, Aleksandra Stamenkovic, Thane G Maddaford, Rakesh Chaudhary, Grant N Pierce, Amir Ravand. Alpha linolenic acid decreases apoptosis and oxidized phospholipids in cardiomyocytes during ischemia/reperfusion. Molecular and cellular biochemistry. vol 437. issue 1-2. 2018-07-09. PMID:28634855. |
alpha linolenic acid decreases apoptosis and oxidized phospholipids in cardiomyocytes during ischemia/reperfusion. |
2018-07-09 |
2023-08-13 |
rat |
| Liliana L Cubas-Gaona, Elisabet Diaz-Beneitez, Marina Ciscar, José F Rodríguez, Dolores Rodrígue. Exacerbated Apoptosis of Cells Infected with Infectious Bursal Disease Virus upon Exposure to Interferon Alpha. Journal of virology. vol 92. issue 11. 2018-06-26. PMID:29540594. |
exacerbated apoptosis of cells infected with infectious bursal disease virus upon exposure to interferon alpha. |
2018-06-26 |
2023-08-13 |
Not clear |
| Atsushi Ueda, Tadayuki Akagi, Takashi Yokot. GA-Binding Protein Alpha Is Involved in the Survival of Mouse Embryonic Stem Cells. Stem cells (Dayton, Ohio). vol 35. issue 11. 2018-06-08. PMID:28762569. |
ets-related transcription factor ga-binding protein alpha (gabpα), which is encoded by gabpa, is expressed in a variety of cell types and is involved in cellular functions such as cell cycle regulation, apoptosis, and differentiation. |
2018-06-08 |
2023-08-13 |
mouse |
| Yulan Yan, Chunxiang Su, Min Hang, Hua Huang, Yinghai Zhao, Xiaomei Shao, Xuefeng B. Recombinant Newcastle disease virus rL-RVG enhances the apoptosis and inhibits the migration of A549 lung adenocarcinoma cells via regulating alpha 7 nicotinic acetylcholine receptors in vitro. Virology journal. vol 14. issue 1. 2018-05-29. PMID:28974241. |
recombinant newcastle disease virus rl-rvg enhances the apoptosis and inhibits the migration of a549 lung adenocarcinoma cells via regulating alpha 7 nicotinic acetylcholine receptors in vitro. |
2018-05-29 |
2023-08-13 |
Not clear |
| Mohammed A El-Magd, Walied S Abdo, Mustafa El-Maddaway, Nasr M Nasr, Rasha A Gaber, Eman S El-Shetry, Ayman A Saleh, Faisal Abdulrahman Ali Alzahrani, Doaa H Abdelhad. High doses of S-methylcysteine cause hypoxia-induced cardiomyocyte apoptosis accompanied by engulfment of mitochondaria by nucleus. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 94. 2018-05-15. PMID:28783581. |
this centripetal movement of mitochondria accompanied by cardiomyocytes hypoxia-induced apoptosis as evident by increasing tunel positive cells as well as upregulation of apoptotic genes (caspase3 and bax), hypoxia inducible factor 1 alpha (hif1α), dynein light chain 1 (dynll1) and downregulation of the anti-apoptotic marker, bcl2. |
2018-05-15 |
2023-08-13 |
rat |
| Enrico Gugliandolo, Roberta Fusco, Flavia Biundo, Ramona D'Amico, Filippo Benedetto, Rosanna Di Paola, Salvatore Cuzzocre. Palmitoylethanolamide and Polydatin combination reduces inflammation and oxidative stress in vascular injury. Pharmacological research. vol 123. 2018-05-10. PMID:28676456. |
in this study we demonstrated that pea/pld combination treatment reduces vessel damage, adhesion molecules expression such as intercellular adhesion molecules-1(icam-1) and vascular cell adhesion molecules-1(v-cam), proinflammatory cytokines production (tumor necrosis factor alpha (tnf-α) and interleukin 1 beta (il-1β), the inducible nitric oxide synthase (inos) and poly (adp-ribose) polymerase (par), formation, nuclear factor kappa-b expression and apoptosis (bax, fas-ligand) activation. |
2018-05-10 |
2023-08-13 |
Not clear |
| Anita Thyagarajan, Jeremiah Saylae, Ravi P Sah. Acetylsalicylic acid inhibits the growth of melanoma tumors via SOX2-dependent-PAF-R-independent signaling pathway. Oncotarget. vol 8. issue 30. 2018-04-23. PMID:28636992. |
similar asa-induced effects in-vitro were seen in human melanoma and nasopharyngeal carcinoma cells positive or negative in paf-r. mechanistically, the asa-induced decrease in cell survival and increase in apoptosis were significantly blocked by prostaglandin f2 alpha (pgf2α) agonists. |
2018-04-23 |
2023-08-13 |
mouse |
| Mingyue Zhu, Wei Li, Yan Lu, Xu Dong, Yi Chen, Bo Lin, Xieju Xie, Junli Guo, Mengsen L. Alpha fetoprotein antagonizes apoptosis induced by paclitaxel in hepatoma cells in vitro. Scientific reports. vol 6. 2018-04-06. PMID:27255186. |
alpha fetoprotein antagonizes apoptosis induced by paclitaxel in hepatoma cells in vitro. |
2018-04-06 |
2023-08-13 |
Not clear |
| Li Wang, Haifeng Li, Shiping Yang, Wenqiang Ma, Mei Liu, Shichao Guo, Jun Zhan, Hongquan Zhang, Suk Ying Tsang, Ziding Zhang, Zhaoyi Wang, Xiru Li, Yang-Dong Guo, Xiangdong L. Cyanidin-3-o-glucoside directly binds to ERα36 and inhibits EGFR-positive triple-negative breast cancer. Oncotarget. vol 7. issue 42. 2018-03-22. PMID:27655695. |
in this study, we found that cyanidin-3-o-glucoside (cy-3-glu) preferentially promotes the apoptosis of tnbc cells, which co-express the estrogen receptor alpha 36 (erα36) and the epidermal growth factor receptor (egfr). |
2018-03-22 |
2023-08-13 |
mouse |
| Emale El Darzi, Samer Bazzi, Sarah Daoud, Karim S Echtay, Georges M Bah. Differential regulation of surface receptor expression, proliferation, and apoptosis in HaCaT cells stimulated with interferon-γ, interleukin-4, tumor necrosis factor-α, or muramyl dipeptide. International journal of immunopathology and pharmacology. vol 30. issue 2. 2018-03-12. PMID:28449603. |
of the stimuli tested, only interferon gamma and tumor necrosis factor alpha significantly inhibited proliferation of hacat cells, yet only interferon gamma played a significant role in inducing hacat cell apoptosis. |
2018-03-12 |
2023-08-13 |
human |
| Yuxuan He, Hongyan Li, Ke Wang, Yong Zhang, Xingxu Zha. Loss of protein kinase 2 subunit alpha 2 (CK2α') effect ram sperm function after freezing and thawing process. Animal reproduction science. vol 181. 2018-03-07. PMID:28366278. |
protein kinase 2 subunit alpha 2 (ck2α'), a serine/threonine-selective protein kinase, is associated with sperm apoptosis. |
2018-03-07 |
2023-08-13 |
Not clear |
| XiangZhen Liu, Juan Chen, ShanHe Yu, Li Yan, HeZhou Guo, JianMin Dai, Wu Zhang, Jiang Zh. All-trans retinoic acid and arsenic trioxide fail to derepress the monocytic differentiation driver Irf8 in acute promyelocytic leukemia cells. Cell death & disease. vol 8. issue 5. 2018-02-16. PMID:28492552. |
all-trans retinoic acid (atra) and/or arsenic trioxide (ato) administration leads to granulocytic maturation and/or apoptosis of acute promyelocytic leukemia (apl) cells mainly by targeting promyelocytic leukemia/retinoic acid receptor alpha (pml/rarα). |
2018-02-16 |
2023-08-13 |
Not clear |
| C Abán, N Martinez, C Carou, I Albamonte, A Toro, A Seyahian, A Franchi, G Leguizamón, D Trigubo, A Damiano, M Farin. Endocannabinoids participate in placental apoptosis induced by hypoxia inducible factor-1. Apoptosis : an international journal on programmed cell death. vol 21. issue 10. 2018-02-13. PMID:27488203. |
in this report, we evaluated the participation of ecs in placental apoptosis induced by cobalt chloride (cocl2), a hypoxia mimicking agent that stabilizes the expression of hypoxia inducible factor-1 alpha (hif-1α). |
2018-02-13 |
2023-08-13 |
human |
| Alfredo Lagunas-Martínez, Enrique García-Villa, Magaly Arellano-Gaytán, Carla O Contreras-Ochoa, Jisela Dimas-González, María E López-Arellano, Vicente Madrid-Marina, Patricio Garigli. MG132 plus apoptosis antigen-1 (APO-1) antibody cooperate to restore p53 activity inducing autophagy and p53-dependent apoptosis in HPV16 E6-expressing keratinocytes. Apoptosis : an international journal on programmed cell death. vol 22. issue 1. 2018-02-12. PMID:27766434. |
finally, using pifithrin alpha we observed a decrease in apoptosis induced by mg132, and by apo-1 plus mg132, suggesting that restoration of apo-1 sensitivity occurs in part through an increase in both the levels and the activity of p53. |
2018-02-12 |
2023-08-13 |
Not clear |
| Liming Yu, Buying Li, Meng Zhang, Zhenxiao Jin, Weixun Duan, Guolong Zhao, Yang Yang, Zhenhua Liu, Wensheng Chen, Siwang Wang, Jian Yang, Dinghua Yi, Jincheng Liu, Shiqiang Y. Melatonin reduces PERK-eIF2α-ATF4-mediated endoplasmic reticulum stress during myocardial ischemia-reperfusion injury: role of RISK and SAFE pathways interaction. Apoptosis : an international journal on programmed cell death. vol 21. issue 7. 2018-02-05. PMID:27170343. |
recently, we demonstrated that melatonin reduced protein kinase rna (pkr)-like er kinase (perk)-eukaryotic initiation factor 2 alpha (eif2α)-activating transcription factor-4 (atf4)-mediated myocardial endoplasmic reticulum (er) stress and apoptosis during myocardial ischemia-reperfusion (mi/r) injury. |
2018-02-05 |
2023-08-13 |
mouse |
| Tereza C Cardoso, Ana Carolina G Rosa, Helena L Ferreira, Lucas H Okamura, Bruna R S M Oliveira, Flavia V Vieira, Camila Silva-Frade, Roberto Gameiro, Eduardo F Flore. Bovine herpesviruses induce different cell death forms in neuronal and glial-derived tumor cell cultures. Journal of neurovirology. vol 22. issue 6. 2018-01-23. PMID:27311457. |
in spite of apoptosis and necroptosis blockage, tumor necrosis factor alpha (tnfa) and virus transcription were positively correlated for all viral strains studied. |
2018-01-23 |
2023-08-13 |
mouse |