| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pierre-François Cartron, Muriel Priault, Lisa Oliver, Khaled Meflah, Stephen Manon, François M Vallett. The N-terminal end of Bax contains a mitochondrial-targeting signal. The Journal of biological chemistry. vol 278. issue 13. 2003-05-02. PMID:12529375. |
the mutations of the eta alpha 1, which inhibit bax alpha and bax psi translocation to mitochondria, also block the subsequent activation of the execution phase of apoptosis. |
2003-05-02 |
2023-08-12 |
Not clear |
| Nikolai Engedal, Heidi Kiil Blomhof. Combined action of ERK and NF kappa B mediates the protective effect of phorbol ester on Fas-induced apoptosis in Jurkat cells. The Journal of biological chemistry. vol 278. issue 13. 2003-05-02. PMID:12551910. |
second, we observed an excellent correlation between repression of tpa-induced nf kappa b activation by an irreversible inhibitor of i kappa b alpha phosphorylation, bay11-7082, and its ability to abrogate tpa-induced suppression of fas-mediated apoptosis. |
2003-05-02 |
2023-08-12 |
Not clear |
| Z Yang, X Yu, Y Qu, H Xi. [The modulation of type I collagen and its receptor system on biological characteristics of osteoblasts]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao. vol 31. issue 3. 2003-04-28. PMID:12545808. |
through blocking type i collagen-receptor system by type i collagen antibody or integrin alpha 2 beta 1 antibody, the proliferation of osteoblasts was studied by cell count, the apoptosis was studied by flow cytometry, and the mrna expressions of type i collagen, integrin alpha 2 beta 1 and osteocalcin were also detected by rt-pcr techniques. |
2003-04-28 |
2023-08-12 |
Not clear |
| Z Yang, X Yu, Y Qu, H Xi. [The modulation of type I collagen and its receptor system on biological characteristics of osteoblasts]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao. vol 31. issue 3. 2003-04-28. PMID:12545808. |
when type i collagen-receptor system was blocked, osteoblasts showed high apoptosis rate, lower growth kinetics and weak mrna expression of type i collagen, integrin alpha 2 beta 1 and osteocalcin; the blocking effect was reversible. |
2003-04-28 |
2023-08-12 |
Not clear |
| Anwu Zhou, Shane Scoggin, Richard B Gaynor, Noelle Sevilir William. Identification of NF-kappa B-regulated genes induced by TNFalpha utilizing expression profiling and RNA interference. Oncogene. vol 22. issue 13. 2003-04-23. PMID:12673210. |
tumor necrosis factor alpha (tnf alpha) is a proinflammatory cytokine with important roles in regulating inflammatory responses as well as cell cycle proliferation and apoptosis. |
2003-04-23 |
2023-08-12 |
human |
| Olivier Meye. [Anti-SSA/Ro and anti-SSB/La antibodies. What's new?]. Annales de medecine interne. vol 153. issue 8. 2003-04-22. PMID:12610426. |
these hyrnps (h=human) can be found on the cytoplasmic membrane or in small blebs during apoptosis after various stimuli such as uvb, 17-beta-estradiol, viral infection, tnf alpha and other cellular apoptosis inducing molecules. |
2003-04-22 |
2023-08-12 |
Not clear |
| Anna Cozzi, Sonia Levi, Barbara Corsi, Paolo Santambrogio, Alessandro Campanella, Gianmario Gerardi, Paolo Arosi. Role of iron and ferritin in TNFalpha-induced apoptosis in HeLa cells. FEBS letters. vol 537. issue 1-3. 2003-04-18. PMID:12606055. |
we found that tumor necrosis factor alpha (tnfalpha)-induced apoptosis in hela cells was accompanied by a approximately 2-fold increase in h- and l-ferritin and a decrease in transferrin receptor, two indices of increased iron availability. |
2003-04-18 |
2023-08-12 |
Not clear |
| Kushlani Gunawardena, Darrell K Murray, Richard E Swope, A Wayne Meikl. Inhibition of nuclear factor kappaB induces apoptosis following treatment with tumor necrosis factor alpha and an antioxidant in human prostate cancer cells. Cancer detection and prevention. vol 26. issue 3. 2003-04-17. PMID:12269771. |
inhibition of nuclear factor kappab induces apoptosis following treatment with tumor necrosis factor alpha and an antioxidant in human prostate cancer cells. |
2003-04-17 |
2023-08-12 |
human |
| Kushlani Gunawardena, Darrell K Murray, Richard E Swope, A Wayne Meikl. Inhibition of nuclear factor kappaB induces apoptosis following treatment with tumor necrosis factor alpha and an antioxidant in human prostate cancer cells. Cancer detection and prevention. vol 26. issue 3. 2003-04-17. PMID:12269771. |
transforming growth factor beta-1 (tgfbeta-1) and tumor necrosis factor alpha (tnf-alpha), an activator of nuclear factor kappa b (nf-kappab), modulate apoptosis and/or cell growth. |
2003-04-17 |
2023-08-12 |
human |
| Min Xia, Cunshuan Xu, Shengdong Ji, Shaobai Xu. Shedding of Fas ectodomain that affects apoptosis of hepatocytes occurring in regenerative liver. Journal of gastroenterology. vol 37. issue 12. 2003-04-11. PMID:12522536. |
on the basis of comprehending several membrane proteins undergoing ectodomain shedding, including tumor necrosis factor (tnf) alpha receptors, we want to know if fas (cd95/apo-1), which belongs to the tnf receptor (tnfr) superfamily and transduces signals resulting in apoptosis upon binding of fas ligand (l) or agonistic anti-fas antibody, is shed on its ectodomain during liver regeneration |
2003-04-11 |
2023-08-12 |
Not clear |
| Subrata K Ghosh, Charles Wood, Lawrence H Boise, Abdul M Mian, Vadim V Deyev, Gerold Feuer, Ngoc L Toomey, Nicole C Shank, Lisa Cabral, Glen N Barber, William J Harringto. Potentiation of TRAIL-induced apoptosis in primary effusion lymphoma through azidothymidine-mediated inhibition of NF-kappa B. Blood. vol 101. issue 6. 2003-04-07. PMID:12406882. |
we have previously demonstrated that the antiviral combination of interferon alpha (ifn-alpha) and azidothymidine (azt) induces apoptosis in pel cell lines. |
2003-04-07 |
2023-08-12 |
human |
| I E Anglin, D T Glassman, N Kypriano. Induction of prostate apoptosis by alpha1-adrenoceptor antagonists: mechanistic significance of the quinazoline component. Prostate cancer and prostatic diseases. vol 5. issue 2. 2003-04-01. PMID:12496995. |
alpha(1)-adrenoceptor antagonists, have been documented to induce apoptosis and reduce prostate tumor vascularity in benign and malignant prostate cells. |
2003-04-01 |
2023-08-12 |
Not clear |
| Bibo Ke, Xiu-Da Shen, Yuan Zhai, Feng Gao, Ronald W Busuttil, Hans-Dieter Volk, Jerzy W Kupiec-Weglinsk. Heme oxygenase 1 mediates the immunomodulatory and antiapoptotic effects of interleukin 13 gene therapy in vivo and in vitro. Human gene therapy. vol 13. issue 15. 2003-03-24. PMID:12396617. |
these findings correlated with in vitro studies in which ad-il-13 decreased tumor necrosis factor alpha (tnf-alpha)-mediated cytotoxicity, conferred resistance to apoptosis, and increased ho-1/a20 expression in human umbilical vein endothelial cell (huvec) cultures. |
2003-03-24 |
2023-08-12 |
human |
| Carla Esposito, Monica Marra, Gaia Giuberti, Anna Maria D'Alessandro, Raffaele Porta, Anna Cozzolino, Michele Caraglia, Alberto Abbruzzes. Ubiquitination of tissue transglutaminase is modulated by interferon alpha in human lung cancer cells. The Biochemical journal. vol 370. issue Pt 1. 2003-03-14. PMID:12401132. |
the addition of 2500 i.u./ml interferon alpha (ifnalpha) for 48 h induced apoptosis, and caused an approx. |
2003-03-14 |
2023-08-12 |
human |
| Denise Perez, Eileen Whit. E1A sensitizes cells to tumor necrosis factor alpha by downregulating c-FLIP S. Journal of virology. vol 77. issue 4. 2003-03-14. PMID:12552004. |
e1a sensitizes cells to tumor necrosis factor alpha by downregulating c-flip s. tumor necrosis factor alpha (tnf-alpha) activates both apoptosis and nf-kappab-dependent survival pathways, the former of which requires inhibition of gene expression to be manifested. |
2003-03-14 |
2023-08-12 |
Not clear |
| Jie Liu, Chengxiu Li, Michael P Waalkes, James Clark, Page Myers, Joseph E Saavedra, Larry K Keefe. The nitric oxide donor, V-PYRRO/NO, protects against acetaminophen-induced hepatotoxicity in mice. Hepatology (Baltimore, Md.). vol 37. issue 2. 2003-03-12. PMID:12540782. |
the liver-selective nitric oxide (no) donor, o(2)-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (v-pyrro/no), is metabolized by p-450 enzymes to release no in the liver, and is shown to protect the liver from tumor necrosis factor alpha (tnf-alpha)-induced apoptosis and d-glactosamine/endotoxin-induced hepatotoxicity. |
2003-03-12 |
2023-08-12 |
mouse |
| Raj K Batra, Ying Lin, Sherven Sharma, Mariam Dohadwala, Jie Luo, Mehis Pold, Steven M Dubinet. Non-small cell lung cancer-derived soluble mediators enhance apoptosis in activated T lymphocytes through an I kappa B kinase-dependent mechanism. Cancer research. vol 63. issue 3. 2003-03-07. PMID:12566308. |
enhanced lymphocyte apoptosis was associated with an impairment of nuclear factor kappa b nuclear translocation and diminished i kappa b alpha degradation. |
2003-03-07 |
2023-08-12 |
Not clear |
| Devin S Gary, Ollivier Milhavet, Simonetta Camandola, Mark P Mattso. Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons. Journal of neurochemistry. vol 84. issue 4. 2003-03-05. PMID:12562530. |
activation of integrins using a peptide containing the amino acid sequence eikllis derived from the alpha chain of laminin protected hippocampal neurons from apoptosis induced by glutamate or staurosporine, and increased akt activity in a beta1 integrin-dependent manner. |
2003-03-05 |
2023-08-12 |
Not clear |
| Kota V Ramana, Brian Friedrich, Aruni Bhatnagar, Satish K Srivastav. Aldose reductase mediates cytotoxic signals of hyperglycemia and TNF-alpha in human lens epithelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 17. issue 2. 2003-02-28. PMID:12490536. |
chronic hyperglycemia and cytokines such as tumor necrosis factor alpha (tnf-alpha) cause oxidative stress leading to dysregulated cell growth or apoptosis that contributes to the development of inflammation and secondary complications of diabetes. |
2003-02-28 |
2023-08-12 |
human |
| R A Roberts, S Chevalier, S C Hasmall, N H James, S C Cosulich, N Macdonal. PPAR alpha and the regulation of cell division and apoptosis. Toxicology. vol 181-182. 2003-02-28. PMID:12505304. |
ppar alpha and the regulation of cell division and apoptosis. |
2003-02-28 |
2023-08-12 |
Not clear |