| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A M Carothers, S A Hughes, D Ortega, M M Bertagnoll. 2-Methoxyestradiol induces p53-associated apoptosis of colorectal cancer cells. Cancer letters. vol 187. issue 1-2. 2003-01-06. PMID:12359354. |
treatment of crc cells with 2-methoxyestradiol (2-meoe(2)) increased expression of p53 and p21(waf1/cip1) proteins and induced apoptosis, but did not produce changes in expression of estrogen receptor (er)alpha or erbeta. |
2003-01-06 |
2023-08-12 |
mouse |
| Kenneth A Voss, Paul C Howard, Ronald T Riley, Raghubir P Sharma, Thomas J Bucci, Ronald J Lorentze. Carcinogenicity and mechanism of action of fumonisin B1: a mycotoxin produced by Fusarium moniliforme (= F. verticillioides). Cancer detection and prevention. vol 26. issue 1. 2003-01-02. PMID:12088196. |
they inhibit ceramide synthase in vitro, enhance tumor necrosis factor alpha (tnfalpha) production, and cause apoptosis. |
2003-01-02 |
2023-08-12 |
mouse |
| Li-fang Fan, Lu-ming Diao, De-ji Chen, Ming-qiu Liu, Li-qin Zhu, Hong-gang Li, Zhi-jiao Tang, Dong Xia, Xuan Liu, Hong-lei Che. [Expression of HIF-1 alpha and its relationship to apoptosis and proliferation in lung cancer]. Ai zheng = Aizheng = Chinese journal of cancer. vol 21. issue 3. 2003-01-02. PMID:12451989. |
[expression of hif-1 alpha and its relationship to apoptosis and proliferation in lung cancer]. |
2003-01-02 |
2023-08-12 |
Not clear |
| Liarisa A Shchepina, Olga Y Pletjushkina, Armine V Avetisyan, Liora E Bakeeva, Elena K Fetisova, Denis S Izyumov, Valeria B Saprunova, Mikhail Y Vyssokikh, Boris V Chernyak, Vladimir P Skulache. Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis. Oncogene. vol 21. issue 53. 2002-12-23. PMID:12444550. |
in the present study, it is shown that release of cytochrome c and apoptosis induced by tumor necrosis factor alpha (tnf) in hela cells can be inhibited by (i) overexpression of an oncoprotein bcl-2, (ii) cyclosporin a, an inhibitor of the mitochondrial permeability transition pore (ptp) or (iii) oligomycin, an inhibitor of h+- atp-synthase. |
2002-12-23 |
2023-08-12 |
Not clear |
| Heinz Baisc. Elevated Ki-67 expression is correlated with TNFalpha- and IFNgamma-induced apoptosis in tumour cells. Cell proliferation. vol 35. issue 6. 2002-12-13. PMID:12427252. |
the expression of ki-67 in tumour cells induced to apoptosis by tumour-necrosis-factor alpha (tnfalpha) and interferon gamma (ifngamma) was studied. |
2002-12-13 |
2023-08-12 |
human |
| Juan L Contreras, Cheryl A Smyth, Guadalupe Bilbao, Carlton J Young, J Anthony Thompson, Devin E Eckhof. 17beta-Estradiol protects isolated human pancreatic islets against proinflammatory cytokine-induced cell death: molecular mechanisms and islet functionality. Transplantation. vol 74. issue 9. 2002-12-13. PMID:12451262. |
proinflammatory cytokines (pic) (interleukin-1beta, interferon-gamma, and tumor necrosis factor alpha) are released after intraportal islet transplantation lead to functional suppression and islet apoptosis. |
2002-12-13 |
2023-08-12 |
human |
| A T Byrne, J Southgate, D R Brison, H J Lees. Effects of insulin-like growth factors I and II on tumour-necrosis-factor-alpha-induced apoptosis in early murine embryos. Reproduction, fertility, and development. vol 14. issue 1-2. 2002-12-11. PMID:12051527. |
the cytokine tumour necrosis factor alpha (tnfalpha) was used to induce apoptosis. |
2002-12-11 |
2023-08-12 |
mouse |
| K-W Lee, P Cohe. Nuclear effects: unexpected intracellular actions of insulin-like growth factor binding protein-3. The Journal of endocrinology. vol 175. issue 1. 2002-12-10. PMID:12379488. |
the recent discovery of the interaction between nuclear igfbp-3 and 9-cis retinoic acid receptor-alpha (retinoid x receptor alpha rxralpha), a nuclear receptor, and its involvement in the regulation of transcriptional signaling and apoptosis represents an important paradigm shift in the understanding of igfbp function. |
2002-12-10 |
2023-08-12 |
Not clear |
| Hsin-Su Yu, Wei-Ting Liao, Kee-Lung Chang, Chia-Li Yu, Gwo-Shing Che. Arsenic induces tumor necrosis factor alpha release and tumor necrosis factor receptor 1 signaling in T helper cell apoptosis. The Journal of investigative dermatology. vol 119. issue 4. 2002-12-10. PMID:12406325. |
arsenic induces tumor necrosis factor alpha release and tumor necrosis factor receptor 1 signaling in t helper cell apoptosis. |
2002-12-10 |
2023-08-12 |
human |
| Astrid J Schraa, Robbert J Kok, Henk E Moorlag, Erwin J Bos, Johannes H Proost, Dirk K F Meijer, Lou F M H de Leij, Grietje Molem. Targeting of RGD-modified proteins to tumor vasculature: a pharmacokinetic and cellular distribution study. International journal of cancer. vol 102. issue 5. 2002-12-10. PMID:12432548. |
cyclic rgd peptides were prior shown to have a high affinity for alpha(v)beta(3) and can induce apoptosis of endothelial cells. |
2002-12-10 |
2023-08-12 |
mouse |
| Keiji Shimada, Mitsutoshi Nakamura, Eiwa Ishida, Munehiro Kishi, Shin Yonehara, Noboru Konish. Contributions of mitogen-activated protein kinase and nuclear factor kappa B to N-(4-hydroxyphenyl)retinamide-induced apoptosis in prostate cancer cells. Molecular carcinogenesis. vol 35. issue 3. 2002-12-09. PMID:12410564. |
we found that nfkappab activation inhibited c-jun nh(2)-terminal kinase and caspase 3 activation induced by 4-hpr and that nfkappab inhibition by the i kappa b alpha phosphorylation inhibitor compound bay 117082 resulted in increasing sensitization of both pc-3 and du145 lines to apoptosis induced by 4-hpr at low concentrations. |
2002-12-09 |
2023-08-12 |
human |
| Ralf Kronenwett, Thorsten Gräf, Wolfgang Nedbal, Markus Weber, Ulrich Steidl, Ulrich-Peter Rohr, Thomas Möhler, Rainer Haa. Inhibition of angiogenesis in vitro by alphav integrin-directed antisense oligonucleotides. Cancer gene therapy. vol 9. issue 7. 2002-12-06. PMID:12082459. |
inhibition of alpha v expression was associated with significant inhibition of migration of huvec by 28% and had no effect on proliferation and apoptosis. |
2002-12-06 |
2023-08-12 |
human |
| Murielle Gantzer, Estelle Spitz, Nathalie Accard, Ronald Rook. Constitutive expression of the adenovirus E3-14.7K protein does not prolong adenovirus vector DNA persistence but protects mice against lipopolysaccharide-induced acute hepatitis. Human gene therapy. vol 13. issue 8. 2002-12-04. PMID:12031125. |
the adenovirus e3 region-encoded 14.7k protein inhibits tumor necrosis factor alpha (tnf-alpha)-induced apoptosis and arachidonic acid synthesis. |
2002-12-04 |
2023-08-12 |
mouse |
| Michael Bergman, Hertzel Salman, Yichayaou Beloosesky, Meir Djaldetti, Hanna Bessle. Are peripheral blood cells from patients with Alzheimer disease more sensitive to apoptotic stimuli? Alzheimer disease and associated disorders. vol 16. issue 3. 2002-12-04. PMID:12218646. |
in addition, the effect of sera from subjects in the three groups on the apoptosis, interleukin (il)-1beta, il-2, il-6, il-10, and tumor necrosis factor (tnf)alpha production by peripheral blood cells from healthy control subjects was examined. |
2002-12-04 |
2023-08-12 |
human |
| Merideth C Kamradt, Feng Chen, Susan Sam, Vincent L Cryn. The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation. The Journal of biological chemistry. vol 277. issue 41. 2002-11-25. PMID:12140279. |
the small heat shock protein alpha b-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation. |
2002-11-25 |
2023-08-12 |
Not clear |
| Merideth C Kamradt, Feng Chen, Susan Sam, Vincent L Cryn. The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation. The Journal of biological chemistry. vol 277. issue 41. 2002-11-25. PMID:12140279. |
here we demonstrate that the expression of the small heat shock protein alpha b-crystallin is selectively induced in c2c12 myoblasts that are resistant to differentiation-induced apoptosis, and we show that this induction occurs at an early stage in their differentiation in vitro. |
2002-11-25 |
2023-08-12 |
Not clear |
| Merideth C Kamradt, Feng Chen, Susan Sam, Vincent L Cryn. The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation. The Journal of biological chemistry. vol 277. issue 41. 2002-11-25. PMID:12140279. |
we also demonstrate that ectopic expression of alpha b-crystallin, but not the closely related small heat shock protein hsp27, renders c2c12 myoblasts resistant to differentiation-induced apoptosis. |
2002-11-25 |
2023-08-12 |
Not clear |
| Merideth C Kamradt, Feng Chen, Susan Sam, Vincent L Cryn. The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation. The Journal of biological chemistry. vol 277. issue 41. 2002-11-25. PMID:12140279. |
finally, we demonstrate that alpha b-crystallin negatively regulates apoptosis during myogenesis by inhibiting the proteolytic activation of caspase-3, whereas the r120g and pseudophosphorylation mutants are defective in this function. |
2002-11-25 |
2023-08-12 |
Not clear |
| Merideth C Kamradt, Feng Chen, Susan Sam, Vincent L Cryn. The small heat shock protein alpha B-crystallin negatively regulates apoptosis during myogenic differentiation by inhibiting caspase-3 activation. The Journal of biological chemistry. vol 277. issue 41. 2002-11-25. PMID:12140279. |
taken together, our findings indicate that alpha b-crystallin is a novel negative regulator of myogenic apoptosis that directly links the differentiation program to apoptosis resistance. |
2002-11-25 |
2023-08-12 |
Not clear |
| Melinda Sue Schwientek, LeeAnn Higgins, Ann Marie Fallo. Cultured Aedes albopictus mosquito cells accumulate elongation factor-1 alpha (EF-1 alpha) during serum starvation. Insect biochemistry and molecular biology. vol 32. issue 9. 2002-11-19. PMID:12213242. |
aside from its importance in the elongation step of protein synthesis, ef-1 alpha has been shown to have a number of non-canonical functions, including interaction with viral rna and a potential role in apoptosis. |
2002-11-19 |
2023-08-12 |
Not clear |