| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chu Chang Chua, Balvin H L Chua, Zhongyi Chen, Cathy Landy, Ronald C Hamd. TGF-beta1 inhibits multiple caspases induced by TNF-alpha in murine osteoblastic MC3T3-E1 cells. Biochimica et biophysica acta. vol 1593. issue 1. 2003-02-27. PMID:12431778. |
tumor necrosis factor alpha (tnf-alpha) is a proinflammatory cytokine that induces apoptosis in a number of cell systems, including osteoblasts. |
2003-02-27 |
2023-08-12 |
Not clear |
| Germán Gallardo, Félix López-Blanco, Carlos M Ruiz de Galarreta, Luisa F Fanju. HMGCoA reductase inhibition partially mediates tumor necrosis factor alpha-induced apoptosis in human U-937 and HL-60 cells. Biochemical and biophysical research communications. vol 300. issue 2. 2003-02-25. PMID:12504097. |
the addition of mevalonate to both u-937 and hl-60 cells could also partially prevent tnf alpha and ceramide-induced apoptosis. |
2003-02-25 |
2023-08-12 |
human |
| Germán Gallardo, Félix López-Blanco, Carlos M Ruiz de Galarreta, Luisa F Fanju. HMGCoA reductase inhibition partially mediates tumor necrosis factor alpha-induced apoptosis in human U-937 and HL-60 cells. Biochemical and biophysical research communications. vol 300. issue 2. 2003-02-25. PMID:12504097. |
these results support the hypothesis that the inhibition of hmgcoa reductase expression and the subsequent decrease in prenylation of proteins such as p21(ras) are part of the mechanism by which tnf alpha induces apoptosis in these cells. |
2003-02-25 |
2023-08-12 |
human |
| Julie Guillermet, Nathalie Saint-Laurent, Philippe Rochaix, Olivier Cuvillier, Thierry Levade, Andrew V Schally, Lucien Pradayrol, Louis Buscail, Christiane Susini, Corinne Bousque. Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 1. 2003-02-21. PMID:12490654. |
sst2 also sensitized these cells to apoptosis induced by tumor necrosis factor alpha (tnfalpha), enhancing it 4.1- +/- 1.5-fold. |
2003-02-21 |
2023-08-12 |
human |
| Ilona Mucsi, Andreas Varga, Masami Kawase, Noboru Motohashi, Joseph Molna. Interaction between various resistance modifiers and apoptosis inducer 12H-benzo[alpha]phenothiazine. Anticancer research. vol 22. issue 5. 2003-02-20. PMID:12530005. |
interaction between various resistance modifiers and apoptosis inducer 12h-benzo[alpha]phenothiazine. |
2003-02-20 |
2023-08-12 |
mouse |
| Ilona Mucsi, Andreas Varga, Masami Kawase, Noboru Motohashi, Joseph Molna. Interaction between various resistance modifiers and apoptosis inducer 12H-benzo[alpha]phenothiazine. Anticancer research. vol 22. issue 5. 2003-02-20. PMID:12530005. |
the effect of some resistance modifiers on apoptosis induction by a benzo[alpha]phenothiazine derivative was studied on the l5178y mouse lymphoma cells (parent) and its multidrug resistant (mdr) subline. |
2003-02-20 |
2023-08-12 |
mouse |
| Ilona Mucsi, Andreas Varga, Masami Kawase, Noboru Motohashi, Joseph Molna. Interaction between various resistance modifiers and apoptosis inducer 12H-benzo[alpha]phenothiazine. Anticancer research. vol 22. issue 5. 2003-02-20. PMID:12530005. |
12h-benzo[alpha]phenothiazine [m627] induced apoptosis both in the parent cells and in the mdr cells. |
2003-02-20 |
2023-08-12 |
mouse |
| Jitsuo Usuda, Song-mao Chiu, Erin S Murphy, Minh Lam, Anna-Liisa Nieminen, Nancy L Oleinic. Domain-dependent photodamage to Bcl-2. A membrane anchorage region is needed to form the target of phthalocyanine photosensitization. The Journal of biological chemistry. vol 278. issue 3. 2003-02-14. PMID:12379660. |
therefore, the alpha(5)/alpha(6) region of bcl-2 is required for photodamage and cross-linking, and domain-dependent photodamage to bcl-2 offers a unique mechanism for activation of apoptosis. |
2003-02-14 |
2023-08-12 |
Not clear |
| Jorge G Ramos, Jorgelina Varayoud, Verónica L Bosquiazzo, Enrique H Luque, Mónica Muñoz-de-Tor. Cellular turnover in the rat uterine cervix and its relationship to estrogen and progesterone receptor dynamics. Biology of reproduction. vol 67. issue 3. 2003-02-13. PMID:12193379. |
proliferation, apoptosis, and progesterone receptor (pr) and estrogen receptor alpha (eralpha) expression were evaluated in cycling, pregnant, and postpartum rats. |
2003-02-13 |
2023-08-12 |
rat |
| Susanne Idel, Peter Ellinghaus, Christian Wolfrum, Jerzy-Roch Nofer, Jolein Gloerich, Gerd Assmann, Friedrich Spener, Udo Seedor. Branched chain fatty acids induce nitric oxide-dependent apoptosis in vascular smooth muscle cells. The Journal of biological chemistry. vol 277. issue 51. 2003-02-12. PMID:12368296. |
we could demonstrate, however, that bcfa induced tumor necrosis factor alpha (tnfalpha) activation and secretion, which is an obligatory step required for induction of apoptosis by bcfas. |
2003-02-12 |
2023-08-12 |
human |
| Carrie J Riendeau, Hardy Kornfel. THP-1 cell apoptosis in response to Mycobacterial infection. Infection and immunity. vol 71. issue 1. 2003-02-10. PMID:12496173. |
we previously reported that mycobacterium tuberculosis infection primes human alveolar macrophages (ham) for tumor necrosis factor alpha (tnf-alpha)-mediated apoptosis and that macrophage apoptosis is associated with killing internalized bacilli. |
2003-02-10 |
2023-08-12 |
human |
| S Talapatra, J D O Wagner, C B Thompso. Elongation factor-1 alpha is a selective regulator of growth factor withdrawal and ER stress-induced apoptosis. Cell death and differentiation. vol 9. issue 8. 2003-01-31. PMID:12107828. |
elongation factor-1 alpha is a selective regulator of growth factor withdrawal and er stress-induced apoptosis. |
2003-01-31 |
2023-08-12 |
Not clear |
| Victoria P Werth, Jesse A Berlin, Jeffrey P Callen, Rosemarie Mick, Kathleen E Sulliva. Mannose binding lectin (MBL) polymorphisms associated with low MBL production in patients with dermatomyositis. The Journal of investigative dermatology. vol 119. issue 6. 2003-01-31. PMID:12485445. |
one theory for the pathophysiology of photosensitive autoimmune skin diseases is that photoinduction of tumor necrosis factor alpha (tnfalpha) secretion leads to keratinocyte apoptosis and translocation of previously sequestered cellular antigens that then activate the immune system. |
2003-01-31 |
2023-08-12 |
Not clear |
| Yifang Wang, Eric Asselin, Benjamin K Tsan. Involvement of transforming growth factor alpha in the regulation of rat ovarian X-linked inhibitor of apoptosis protein expression and follicular growth by follicle-stimulating hormone. Biology of reproduction. vol 66. issue 6. 2003-01-14. PMID:12021046. |
involvement of transforming growth factor alpha in the regulation of rat ovarian x-linked inhibitor of apoptosis protein expression and follicular growth by follicle-stimulating hormone. |
2003-01-14 |
2023-08-12 |
rat |
| Fangming Tang, Guilin Tang, Jialing Xiang, Qing Dai, Marsha R Rosner, Anning Li. The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis. Molecular and cellular biology. vol 22. issue 24. 2003-01-13. PMID:12446776. |
the proinflammatory cytokine tumor necrosis factor alpha (tnf-alpha) regulates immune responses, inflammation, and programmed cell death (apoptosis). |
2003-01-13 |
2023-08-12 |
mouse |
| Rosa Maria Borzi, Ilaria Mazzetti, Giorgia Magagnoli, Samantha Paoletti, Mariagrazia Uguccioni, Rita Gatti, Guido Orlandini, Luca Cattini, Andrea Facchin. Growth-related oncogene alpha induction of apoptosis in osteoarthritis chondrocytes. Arthritis and rheumatism. vol 46. issue 12. 2003-01-10. PMID:12483724. |
growth-related oncogene alpha induction of apoptosis in osteoarthritis chondrocytes. |
2003-01-10 |
2023-08-12 |
Not clear |
| A Louise McCormick, Vanessa L Smith, Dar Chow, Edward S Mocarsk. Disruption of mitochondrial networks by the human cytomegalovirus UL37 gene product viral mitochondrion-localized inhibitor of apoptosis. Journal of virology. vol 77. issue 1. 2003-01-09. PMID:12477866. |
these alterations were associated with expression of the immediate-early (alpha) antiapoptotic ul37x1 gene product viral mitochondrion-localized inhibitor of apoptosis (vmia). |
2003-01-09 |
2023-08-12 |
human |
| Katja Schorr, Gerhild Taimor, Heike Degenhardt, Kerstin Weber, Klaus-Dieter Schlüte. Parathyroid hormone-related peptide is induced by stimulation of alpha 1A-adrenoceptors and improves resistance against apoptosis in coronary endothelial cells. Molecular pharmacology. vol 63. issue 1. 2003-01-09. PMID:12488543. |
parathyroid hormone-related peptide is induced by stimulation of alpha 1a-adrenoceptors and improves resistance against apoptosis in coronary endothelial cells. |
2003-01-09 |
2023-08-12 |
Not clear |
| Satoshi Nomoto, Yukitomo Arao, Hyogo Horiguchi, Kazuhiro Ikeda, Fujio Kayam. Oestrogen causes G2/M arrest and apoptosis in breast cancer cells MDA-MB-231. Oncology reports. vol 9. issue 4. 2003-01-08. PMID:12066207. |
cell-cycle arrest at g2/m began at 6 h after treatment, and apoptosis began within 24 h. because mda-mb-231 cells are er alpha negative, these results suggest that oestradiol induces cell-cycle arrest and apoptosis through an er alpha-independent pathway. |
2003-01-08 |
2023-08-12 |
Not clear |
| A Mobasher. Role of chondrocyte death and hypocellularity in ageing human articular cartilage and the pathogenesis of osteoarthritis. Medical hypotheses. vol 58. issue 3. 2003-01-07. PMID:12018969. |
although nitric oxide and fas ligand have been shown to be inducers of chondrocyte apoptosis in vitro and in vivo, the contribution of other triggers such as hypoxia, matrix acidosis, abnormal shear stress and catabolic cytokines like interleukin-1beta and tumour necrosis factor alpha has not been examined. |
2003-01-07 |
2023-08-12 |
human |