| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Philip R Dash, Judith E Cartwright, Philip N Baker, Alan P Johnstone, Guy St J Whitle. Nitric oxide protects human extravillous trophoblast cells from apoptosis by a cyclic GMP-dependent mechanism and independently of caspase 3 nitrosylation. Experimental cell research. vol 287. issue 2. 2003-08-15. PMID:12837287. |
nitric oxide produced exogenously by the addition of no donors was able to delay or inhibit apoptosis induced by a combination of tumour necrosis factor alpha and actinomycin d and to suppress the activity of caspase 3. |
2003-08-15 |
2023-08-12 |
human |
| Huang Shao, Haiyun Y Cheng, Richard G Cook, David J Tweard. Identification and characterization of signal transducer and activator of transcription 3 recruitment sites within the epidermal growth factor receptor. Cancer research. vol 63. issue 14. 2003-08-13. PMID:12873986. |
in squamous cell carcinoma of the head and neck, stat3 activation is mediated by up-regulation of the autocrine ligand-receptor pair, tumor growth factor alpha and epidermal growth factor receptor (egfr), resulting in cell growth and resistance to apoptosis. |
2003-08-13 |
2023-08-12 |
human |
| Graham P Pidgeon, Keqin Tang, Yin Long Cai, Evano Piasentin, Kenneth V Hon. Overexpression of platelet-type 12-lipoxygenase promotes tumor cell survival by enhancing alpha(v)beta(3) and alpha(v)beta(5) integrin expression. Cancer research. vol 63. issue 14. 2003-08-13. PMID:12874035. |
treatment of both transfected cell lines with monoclonal antibody to alpha(v)beta(5) (and in the case of pc3 cells, anti-alpha(v)beta(3)) resulted in significant apoptosis. |
2003-08-13 |
2023-08-12 |
Not clear |
| Graham P Pidgeon, Keqin Tang, Yin Long Cai, Evano Piasentin, Kenneth V Hon. Overexpression of platelet-type 12-lipoxygenase promotes tumor cell survival by enhancing alpha(v)beta(3) and alpha(v)beta(5) integrin expression. Cancer research. vol 63. issue 14. 2003-08-13. PMID:12874035. |
the results show that 12-lox regulates cell survival and apoptosis by affecting the expression and localization of the vitronectin receptors, alpha(v)beta(3) and alpha(v)beta(5), in two cancer cell lines. |
2003-08-13 |
2023-08-12 |
Not clear |
| A V Alessenko, E I Galperin, L B Dudnik, V G Korobko, E S Mochalova, L V Platonova, L N Shingarova, N I Shono, M A Shupi. Role of tumor necrosis factor alpha and sphingomyelin cycle activation in the induction of apoptosis by ischemia/reperfusion of the liver. Biochemistry. Biokhimiia. vol 67. issue 12. 2003-08-04. PMID:12600263. |
role of tumor necrosis factor alpha and sphingomyelin cycle activation in the induction of apoptosis by ischemia/reperfusion of the liver. |
2003-08-04 |
2023-08-12 |
rat |
| Margot L Goodkin, Adrian T Ting, John A Blah. NF-kappaB is required for apoptosis prevention during herpes simplex virus type 1 infection. Journal of virology. vol 77. issue 13. 2003-08-01. PMID:12805425. |
we now report that (i) during the prevention window, hsv-1(f) also inhibited apoptosis induced by tumor necrosis factor alpha (tnf-alpha) plus cycloheximide (chx) treatment. |
2003-08-01 |
2023-08-12 |
human |
| Pierre Ambrosi, Patrick Villani, Gilbert Habib, Gilles Bouveno. [The statins: new properties]]. Therapie. vol 58. issue 1. 2003-07-24. PMID:12822196. |
in vitro, and in animal models, the inhibition of rho with statins results in a decrease in endothelial nitric oxide production, an inhibition of leucocyte adhesion on endothelium, decrease in ppar alpha activation and high density lipoprotein (hdl) production by the hepatocyte, decrease in ca2+ stores in vascular smooth cells, and a stimulation of vascular smooth muscle cell apoptosis. |
2003-07-24 |
2023-08-12 |
Not clear |
| Joo-Byoung Yoon, Song-Ja Kim, Sang-Gu Hwang, Sunghoe Chang, Shin-Sung Kang, Jang-Soo Chu. Non-steroidal anti-inflammatory drugs inhibit nitric oxide-induced apoptosis and dedifferentiation of articular chondrocytes independent of cyclooxygenase activity. The Journal of biological chemistry. vol 278. issue 17. 2003-07-16. PMID:12588866. |
nitric oxide (no) causes apoptosis and dedifferentiation of articular chondrocytes by the modulation of extracellular signal-regulated kinase (erk), p38 kinase, and protein kinase c (pkc) alpha and -zeta. |
2003-07-16 |
2023-08-12 |
Not clear |
| Kevin Rostasy, Christophe Egles, Ashok Chauhan, Michelle Kneissl, Padmanabhan Bahrani, Constantin Yiannoutsos, Dale D Hunter, Avindra Nath, John C Hedreen, Bradford A Navi. SDF-1alpha is expressed in astrocytes and neurons in the AIDS dementia complex: an in vivo and in vitro study. Journal of neuropathology and experimental neurology. vol 62. issue 6. 2003-07-16. PMID:12834106. |
recent in vitro studies suggest that the alpha chemokine stromal-derived factor-1alpha (sdf-1alpha) and its receptor cxcr-4 may contribute to neuronal apoptosis in hiv infection of the brain. |
2003-07-16 |
2023-08-12 |
mouse |
| b' V Cupi\\xc4\\x87, M Coli\\xc4\\x87, D Jandri\\xc4\\x87, B Milojkovi\\xc4\\x87, V M Varagi\\xc4\\x8. Xylazine, an alpha 2-adrenergic agonist, induces apoptosis of rat thymocytes and a thymocyte hybridoma line in vitro. Methods and findings in experimental and clinical pharmacology. vol 25. issue 1. 2003-07-14. PMID:12690700.' |
xylazine, an alpha 2-adrenergic agonist, induces apoptosis of rat thymocytes and a thymocyte hybridoma line in vitro. |
2003-07-14 |
2023-08-12 |
rat |
| Rihab Nasr, Andreas Rosenwald, Marwan E El-Sabban, Bertrand Arnulf, Pierre Zalloua, Yves Lepelletier, Françoise Bex, Olivier Hermine, Louis Staudt, Hugues de Thé, Ali Bazarbach. Arsenic/interferon specifically reverses 2 distinct gene networks critical for the survival of HTLV-1-infected leukemic cells. Blood. vol 101. issue 11. 2003-07-11. PMID:12560223. |
because arsenic trioxide (as) and interferon alpha (ifn) synergize to induce cell cycle arrest and apoptosis of atl cells both ex vivo and in vitro, we investigated the effects of as alone and as/ifn combination on gene networks in htlv-1-infected leukemic cells. |
2003-07-11 |
2023-08-12 |
human |
| X Deng, S M Kornblau, P P Ruvolo, W S Ma. Regulation of Bcl2 phosphorylation and potential significance for leukemic cell chemoresistance. Journal of the National Cancer Institute. Monographs. issue 28. 2003-07-01. PMID:11158204. |
phosphorylation of bcl2 at serine 70 is required for suppression of apoptosis in interleukin 3 (il-3)-dependent myeloid cells deprived of il-3 or treated with antileukemic drugs and can result from agonist activation of mitochondrial protein kinase c alpha (pkcalpha). |
2003-07-01 |
2023-08-12 |
Not clear |
| Shigeru Nakashim. Protein kinase C alpha (PKC alpha): regulation and biological function. Journal of biochemistry. vol 132. issue 5. 2003-07-01. PMID:12417014. |
therefore, pkc alpha has been implicated in a variety of cellular functions including proliferation, apoptosis, differentiation, motility, and inflammation. |
2003-07-01 |
2023-08-12 |
Not clear |
| Olga V Markova, Alexandra G Evstafieva, Svetlana E Mansurova, Sergey S Moussine, Larisa A Palamarchuk, Mikhail O Pereverzev, Andrey B Vartapetian, Vladimir P Skulache. Cytochrome c is transformed from anti- to pro-oxidant when interacting with truncated oncoprotein prothymosin alpha. Biochimica et biophysica acta. vol 1557. issue 1-3. 2003-06-27. PMID:12615354. |
on the other hand, in this group, it was shown that prothymosin alpha (pt), a small nuclear protein where 53 of 109 amino acid residues are negatively charged, is truncated to form a protein of 99 amino acid residues which accumulates in cytosol during apoptosis [febs lett. |
2003-06-27 |
2023-08-12 |
Not clear |
| Miho Ueda, Satoshi Kokura, Eiko Imamoto, Yuji Naito, Osamu Handa, Tomohisa Takagi, Norimasa Yoshida, Toshikazu Yoshikaw. Blocking of NF-kappaB activation enhances the tumor necrosis factor alpha-induced apoptosis of a human gastric cancer cell line. Cancer letters. vol 193. issue 2. 2003-06-27. PMID:12706875. |
this study investigated the mechanism by which human gastric cancer cells (mkn45) are resistant to apoptosis induced by tumor necrosis factor alpha (tnf-alpha). |
2003-06-27 |
2023-08-12 |
human |
| J V Partin, I E Anglin, N Kypriano. Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction. British journal of cancer. vol 88. issue 10. 2003-06-26. PMID:12771931. |
quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via tgf-beta signalling and i kappa b alpha induction. |
2003-06-26 |
2023-08-12 |
human |
| J V Partin, I E Anglin, N Kypriano. Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction. British journal of cancer. vol 88. issue 10. 2003-06-26. PMID:12771931. |
previous studies documented the ability of quinazoline-based alpha1-adrenoceptor antagonists to induce apoptosis in prostate cancer cells via an alpha 1-adrenoceptor-independent mechanism. |
2003-06-26 |
2023-08-12 |
human |
| J V Partin, I E Anglin, N Kypriano. Quinazoline-based alpha 1-adrenoceptor antagonists induce prostate cancer cell apoptosis via TGF-beta signalling and I kappa B alpha induction. British journal of cancer. vol 88. issue 10. 2003-06-26. PMID:12771931. |
these findings suggest that the quinazoline-based doxazosin mediates prostate cancer apoptosis by initially inducing the expression of tgf-beta1 signalling effectors and subsequently i kappa b alpha. |
2003-06-26 |
2023-08-12 |
human |
| Scott D Kobayashi, Jovanka M Voyich, Kevin R Braughton, Frank R DeLe. Down-regulation of proinflammatory capacity during apoptosis in human polymorphonuclear leukocytes. Journal of immunology (Baltimore, Md. : 1950). vol 170. issue 6. 2003-06-25. PMID:12626596. |
we used flow cytometry to confirm that il-8r beta (cxcr2) and il-1 alpha were significantly down-regulated during pmn apoptosis. |
2003-06-25 |
2023-08-12 |
human |
| M Dahmoun, T Bäckström, K Boman, S Cajande. Apoptosis, proliferation, and hormone receptors in endometrial carcinoma: results depending on methods of analysis. International journal of oncology. vol 22. issue 1. 2003-06-16. PMID:12469193. |
apoptosis and proliferation were studied in 29 endometrial adenocarcinomas of the endometrioid type and characterized by the immunohisto-chemical pattern of estrogen receptor (er) alpha and progesterone receptor (pr) expression. |
2003-06-16 |
2023-08-12 |
Not clear |