| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Emoto, K Nakamura, Y Nagasaka, F Numa, Y Suminami, H Kat. Alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. Apoptosis : an international journal on programmed cell death. vol 3. issue 3. 2003-12-23. PMID:14646496. |
alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. |
2003-12-23 |
2023-08-12 |
rat |
| T Emoto, K Nakamura, Y Nagasaka, F Numa, Y Suminami, H Kat. Alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. Apoptosis : an international journal on programmed cell death. vol 3. issue 3. 2003-12-23. PMID:14646496. |
we have demonstrated that alpha 1act inhibited chymotrypsin-induced apoptosis in rat hepatoma h4 cells. |
2003-12-23 |
2023-08-12 |
rat |
| T Emoto, K Nakamura, Y Nagasaka, F Numa, Y Suminami, H Kat. Alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. Apoptosis : an international journal on programmed cell death. vol 3. issue 3. 2003-12-23. PMID:14646496. |
even low concentrations of chymotrypsin (but not trypsin) induce apoptosis in h4 cells with a minimum effective concentration of 2.4 x 10(-2) units/ml (0.5 microg/ml), and this apoptosis was inhibited by alpha 1act in a concentration-dependent manner. |
2003-12-23 |
2023-08-12 |
rat |
| T Emoto, K Nakamura, Y Nagasaka, F Numa, Y Suminami, H Kat. Alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. Apoptosis : an international journal on programmed cell death. vol 3. issue 3. 2003-12-23. PMID:14646496. |
furthermore, the concentrations of alpha 1act required to inhibit the apoptosis were lower than normal serum levels. |
2003-12-23 |
2023-08-12 |
rat |
| T Emoto, K Nakamura, Y Nagasaka, F Numa, Y Suminami, H Kat. Alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. Apoptosis : an international journal on programmed cell death. vol 3. issue 3. 2003-12-23. PMID:14646496. |
these results may indicate that alpha 1act plays a role in the apoptosis of rat hepatoma cells. |
2003-12-23 |
2023-08-12 |
rat |
| U Brinkmann, E Mansfield, I Pasta. Effects of BCL-2 overexpression on the sensitivity of MCF-7 breast cancer cells to ricin, diphtheria and Pseudomonas toxin and immunotoxins. Apoptosis : an international journal on programmed cell death. vol 2. issue 2. 2003-12-23. PMID:14646554. |
we compared the sensitivity of mcf-7 breast cancer cells that were stably transfected with a bcl-2 expression plasmid and thus protected against apoptosis and of mcf-7 cells transfected with a control plasmid towards ricin, diphtheria and pseudomonas toxin, a pseudomonas toxin-derived immunotoxin (lmb-7) and tumour necrosis factor alpha (tnf). |
2003-12-23 |
2023-08-12 |
Not clear |
| Neera V Gopee, Quanren He, Raghubir P Sharm. Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-kappaB and tumor necrosis factor alpha in LLC-PK1 cells. Chemico-biological interactions. vol 146. issue 2. 2003-12-16. PMID:14597127. |
fumonisin b1-induced apoptosis is associated with delayed inhibition of protein kinase c, nuclear factor-kappab and tumor necrosis factor alpha in llc-pk1 cells. |
2003-12-16 |
2023-08-12 |
Not clear |
| Kotaro Fukushima, Shingo Miyamoto, Hajime Komatsu, Kiyomi Tsukimori, Hiroaki Kobayashi, Hiroyuki Seki, Satoru Takeda, Hitoo Nakan. TNFalpha-induced apoptosis and integrin switching in human extravillous trophoblast cell line. Biology of reproduction. vol 68. issue 5. 2003-12-12. PMID:12606473. |
we found that tumor necrosis factor alpha (tnfalpha) induced apoptosis in tcl1 cells but not in jeg3 cells derived from choriocarcinoma while the addition of interleukin-1beta, leukemia inhibitory factor, or transforming growth factor had no effect on tcl1 cells. |
2003-12-12 |
2023-08-12 |
human |
| Anke Luhe, Heinz Hildebrand, Ute Bach, Theodor Dingermann, Hans-Jurgen Ah. A new approach to studying ochratoxin A (OTA)-induced nephrotoxicity: expression profiling in vivo and in vitro employing cDNA microarrays. Toxicological sciences : an official journal of the Society of Toxicology. vol 73. issue 2. 2003-12-10. PMID:12700408. |
marked treatment-specific transcriptional changes were detected for genes involved in dna damage response and apoptosis (upregulation of gadd 153, gadd 45, annexin v), response to oxidative stress (differential expression of hypoxia-inducible factor 1 and catalase), and inflammatory reactions (upregulation of alpha 2 macroglobulin, ceruloplasmin, and cathepsin s). |
2003-12-10 |
2023-08-12 |
rat |
| Paolo Puddu, Giovanni M Puddu, Antonio Muscar. Peroxisome proliferator-activated receptors: are they involved in atherosclerosis progression? International journal of cardiology. vol 90. issue 2-3. 2003-12-09. PMID:12957742. |
ppar alpha and gamma are the two main categories of these receptors, which are both characterized by their ability to influence lipid metabolism, glucose homeostasis, cell proliferation, differentiation and apoptosis, as well as the inflammatory response, by transcriptional activation of target genes. |
2003-12-09 |
2023-08-12 |
Not clear |
| H Nakae, Y-J Zheng, H Wada, K Tajimi, S End. Involvement of IL-18 and soluble fas in patients with postoperative hepatic failure. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. vol 35. issue 2. 2003-12-05. PMID:12679613. |
we measured the levels of tumor necrosis factor alpha (tnf-alpha), interleukins (il)-6 and -18, and soluble fas (sfas) in 11 patients with postoperative hepatic failure and assessed whether il-18-mediated apoptosis is involved in the onset of liver dysfunction. |
2003-12-05 |
2023-08-12 |
Not clear |
| Amy L Howes, Jane F Arthur, Tong Zhang, Shigeki Miyamoto, John W Adams, Gerald W Dorn, Elizabeth A Woodcock, Joan Heller Brow. Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion. The Journal of biological chemistry. vol 278. issue 41. 2003-12-02. PMID:12900409. |
expression of the wild type alpha subunit of gq (gqwt) in cardiomyocytes induces hypertrophy, whereas a constitutively active g alpha q subunit (gqq209l) induces apoptosis. |
2003-12-02 |
2023-08-12 |
mouse |
| Amy L Howes, Jane F Arthur, Tong Zhang, Shigeki Miyamoto, John W Adams, Gerald W Dorn, Elizabeth A Woodcock, Joan Heller Brow. Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion. The Journal of biological chemistry. vol 278. issue 41. 2003-12-02. PMID:12900409. |
in transgenic mice with cardiac g alpha q overexpression, heart failure and increased cardiomyocyte apoptosis develop during the peripartal period. |
2003-12-02 |
2023-08-12 |
mouse |
| K Sato, U Aytac, T Yamochi, T Yamochi, K Ohnuma, K S McKee, C Morimoto, N H Dan. CD26/dipeptidyl peptidase IV enhances expression of topoisomerase II alpha and sensitivity to apoptosis induced by topoisomerase II inhibitors. British journal of cancer. vol 89. issue 7. 2003-11-25. PMID:14520473. |
cd26/dipeptidyl peptidase iv enhances expression of topoisomerase ii alpha and sensitivity to apoptosis induced by topoisomerase ii inhibitors. |
2003-11-25 |
2023-08-12 |
Not clear |
| R Sasson, A Amsterda. Pleiotropic anti-apoptotic activity of glucocorticoids in ovarian follicular cells. Biochemical pharmacology. vol 66. issue 8. 2003-11-20. PMID:14555213. |
glucocorticoids (gc) such as hydrocortisone and dexamethasone (dex) protect steroidogenic granulosa cells against apoptosis induced by serum deprivation, camp, tumor necrosis factor alpha stimulation or p53 activation. |
2003-11-20 |
2023-08-12 |
human |
| Christophe Cataisson, Elizabeth Joseloff, Rodolfo Murillas, Alice Wang, Coralyn Atwell, Sara Torgerson, Michael Gerdes, Jeffrey Subleski, Ji-Liang Gao, Philip M Murphy, Robert H Wiltrout, Charles Vinson, Stuart H Yusp. Activation of cutaneous protein kinase C alpha induces keratinocyte apoptosis and intraepidermal inflammation by independent signaling pathways. Journal of immunology (Baltimore, Md. : 1950). vol 171. issue 5. 2003-11-17. PMID:12928424. |
activation of cutaneous protein kinase c alpha induces keratinocyte apoptosis and intraepidermal inflammation by independent signaling pathways. |
2003-11-17 |
2023-08-12 |
mouse |
| Takeshi Hayashi, Atsushi Saito, Shuzo Okuno, Michel Ferrand-Drake, Robert L Dodd, Tatsuro Nishi, Carolina M Maier, Hiroyuki Kinouchi, Pak H Cha. Oxidative damage to the endoplasmic reticulum is implicated in ischemic neuronal cell death. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 23. issue 10. 2003-11-12. PMID:14526222. |
phosphorylated forms of eukaryotic initiation factor 2 alpha (eif2 alpha) and rna-dependent protein kinase-like er eif2 alpha kinase (perk), both of which play active roles in apoptosis, were increased in hippocampal ca1 neurons after ischemia but to a lesser degree in the transgenic animals. |
2003-11-12 |
2023-08-12 |
rat |
| Li-yong Yang, Yong-nian Yang, Zhi-jian Che. [Role of nuclear factor of kB in tumor necrosis factor alpha-mediated INS-1 cell apoptosis]. Zhonghua yi xue za zhi. vol 83. issue 8. 2003-10-30. PMID:12887830. |
to investigate the effect of cytokine tumor necrosis factor alpha(tnfalpha) on pancreatic beta cells apoptosis and the effect of transcription factor nuclear factor of kappa b (nf-kb) on tnfalpha-mediated apoptosis. |
2003-10-30 |
2023-08-12 |
Not clear |
| Xin Jiang, Michael Norman, Xianqiang L. Use of an array technology for profiling and comparing transcription factors activated by TNFalpha and PMA in HeLa cells. Biochimica et biophysica acta. vol 1642. issue 1-2. 2003-10-28. PMID:12972287. |
tumor necrosis factor alpha (tnfalpha) and phorbol 12-myristate 13-acetate (pma) mediate many biological functions, including cell proliferation and apoptosis, by stimulating signaling pathways. |
2003-10-28 |
2023-08-12 |
Not clear |
| Vyacheslav A Adarichev, Rita Vaiskunaite, Jiaxin Niu, Irina V Balyasnikova, Tatyana A Voyno-Yasenetskay. G alpha 13-mediated transformation and apoptosis are permissively dependent on basal ERK activity. American journal of physiology. Cell physiology. vol 285. issue 4. 2003-10-23. PMID:12736137. |
g alpha 13-mediated transformation and apoptosis are permissively dependent on basal erk activity. |
2003-10-23 |
2023-08-12 |
human |