| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sei-Jung Lee, Kyung-Sun Heo, Phil-Sun Oh, Kwang Lim, Kye-Taek Li. Glycoprotein isolated from Ulmus davidiana Nakai inhibits TPA-induced apoptosis through nuclear factor-kappa B in NIH/3T3 cells. Toxicology letters. vol 146. issue 2. 2004-01-06. PMID:14643968. |
to investigate the anti-apoptotic effects of udn glycoprotein, we investigated the activity of protein kinase c alpha (pkcalpha), the dna-binding activation of nuclear factor-kappa b (nf-kappab), the production of nitric oxide (no) and apoptosis in 12-o-tetradecanoylphorbol 13-acetate (tpa)-stimulated nih/3t3 cells using a western blot analysis, electrophoretic mobility shift assays (emsa) and no assays. |
2004-01-06 |
2023-08-12 |
Not clear |
| Satoshi Kokura, Norimasa Yoshida, Miho Ueda, Eiko Imamoto, Takeshi Ishikawa, Tomohisa Takagi, Yuji Naito, Takeshi Okanoue, Toshikazu Yoshikaw. Hyperthermia enhances tumor necrosis factor alpha-induced apoptosis of a human gastric cancer cell line. Cancer letters. vol 201. issue 1. 2004-01-05. PMID:14580690. |
we have investigated the effects of hyperthermia on the apoptosis induced by tumor necrosis factor alpha (tnf-alpha). |
2004-01-05 |
2023-08-12 |
human |
| J Dong, M Naito, S Dan, T Tsuru. Establishment of a mutant from human monocytic leukaemia U937 that exhibits a genetically dominant resistance to TNF alpha-induced apoptosis. Apoptosis : an international journal on programmed cell death. vol 3. issue 4. 2003-12-23. PMID:14646488. |
tumour necrosis factor-alpha (tnf alpha) is a cytokine that induces apoptosis in various cell systems by binding to a tnf receptor (tnfr). |
2003-12-23 |
2023-08-12 |
human |
| J Dong, M Naito, S Dan, T Tsuru. Establishment of a mutant from human monocytic leukaemia U937 that exhibits a genetically dominant resistance to TNF alpha-induced apoptosis. Apoptosis : an international journal on programmed cell death. vol 3. issue 4. 2003-12-23. PMID:14646488. |
to study tnf alpha-induced apoptosis, we isolated and characterized a novel tnf alpha resistant variant, u937/tnf clone ii-5, from human monocytic leukaemia u937 cells. |
2003-12-23 |
2023-08-12 |
human |
| J Dong, M Naito, S Dan, T Tsuru. Establishment of a mutant from human monocytic leukaemia U937 that exhibits a genetically dominant resistance to TNF alpha-induced apoptosis. Apoptosis : an international journal on programmed cell death. vol 3. issue 4. 2003-12-23. PMID:14646488. |
the ii-5 cells resist apoptosis by tnf alpha and anti-fas antibody but not by anticancer drugs, such as vp-16 and ara-c. somatic cell hybridization between u937 and ii-5 showed that the apoptosis resistance to tnf alpha in ii-5 was genetically dominant. |
2003-12-23 |
2023-08-12 |
human |
| T Emoto, K Nakamura, Y Nagasaka, F Numa, Y Suminami, H Kat. Alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. Apoptosis : an international journal on programmed cell death. vol 3. issue 3. 2003-12-23. PMID:14646496. |
alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. |
2003-12-23 |
2023-08-12 |
rat |
| T Emoto, K Nakamura, Y Nagasaka, F Numa, Y Suminami, H Kat. Alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. Apoptosis : an international journal on programmed cell death. vol 3. issue 3. 2003-12-23. PMID:14646496. |
we have demonstrated that alpha 1act inhibited chymotrypsin-induced apoptosis in rat hepatoma h4 cells. |
2003-12-23 |
2023-08-12 |
rat |
| T Emoto, K Nakamura, Y Nagasaka, F Numa, Y Suminami, H Kat. Alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. Apoptosis : an international journal on programmed cell death. vol 3. issue 3. 2003-12-23. PMID:14646496. |
even low concentrations of chymotrypsin (but not trypsin) induce apoptosis in h4 cells with a minimum effective concentration of 2.4 x 10(-2) units/ml (0.5 microg/ml), and this apoptosis was inhibited by alpha 1act in a concentration-dependent manner. |
2003-12-23 |
2023-08-12 |
rat |
| T Emoto, K Nakamura, Y Nagasaka, F Numa, Y Suminami, H Kat. Alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. Apoptosis : an international journal on programmed cell death. vol 3. issue 3. 2003-12-23. PMID:14646496. |
furthermore, the concentrations of alpha 1act required to inhibit the apoptosis were lower than normal serum levels. |
2003-12-23 |
2023-08-12 |
rat |
| T Emoto, K Nakamura, Y Nagasaka, F Numa, Y Suminami, H Kat. Alpha 1-antichymotrypsin inhibits chymotrypsin-induced apoptosis in rat hepatoma cells. Apoptosis : an international journal on programmed cell death. vol 3. issue 3. 2003-12-23. PMID:14646496. |
these results may indicate that alpha 1act plays a role in the apoptosis of rat hepatoma cells. |
2003-12-23 |
2023-08-12 |
rat |
| U Brinkmann, E Mansfield, I Pasta. Effects of BCL-2 overexpression on the sensitivity of MCF-7 breast cancer cells to ricin, diphtheria and Pseudomonas toxin and immunotoxins. Apoptosis : an international journal on programmed cell death. vol 2. issue 2. 2003-12-23. PMID:14646554. |
we compared the sensitivity of mcf-7 breast cancer cells that were stably transfected with a bcl-2 expression plasmid and thus protected against apoptosis and of mcf-7 cells transfected with a control plasmid towards ricin, diphtheria and pseudomonas toxin, a pseudomonas toxin-derived immunotoxin (lmb-7) and tumour necrosis factor alpha (tnf). |
2003-12-23 |
2023-08-12 |
Not clear |
| Neera V Gopee, Quanren He, Raghubir P Sharm. Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-kappaB and tumor necrosis factor alpha in LLC-PK1 cells. Chemico-biological interactions. vol 146. issue 2. 2003-12-16. PMID:14597127. |
fumonisin b1-induced apoptosis is associated with delayed inhibition of protein kinase c, nuclear factor-kappab and tumor necrosis factor alpha in llc-pk1 cells. |
2003-12-16 |
2023-08-12 |
Not clear |
| Kotaro Fukushima, Shingo Miyamoto, Hajime Komatsu, Kiyomi Tsukimori, Hiroaki Kobayashi, Hiroyuki Seki, Satoru Takeda, Hitoo Nakan. TNFalpha-induced apoptosis and integrin switching in human extravillous trophoblast cell line. Biology of reproduction. vol 68. issue 5. 2003-12-12. PMID:12606473. |
we found that tumor necrosis factor alpha (tnfalpha) induced apoptosis in tcl1 cells but not in jeg3 cells derived from choriocarcinoma while the addition of interleukin-1beta, leukemia inhibitory factor, or transforming growth factor had no effect on tcl1 cells. |
2003-12-12 |
2023-08-12 |
human |
| Anke Luhe, Heinz Hildebrand, Ute Bach, Theodor Dingermann, Hans-Jurgen Ah. A new approach to studying ochratoxin A (OTA)-induced nephrotoxicity: expression profiling in vivo and in vitro employing cDNA microarrays. Toxicological sciences : an official journal of the Society of Toxicology. vol 73. issue 2. 2003-12-10. PMID:12700408. |
marked treatment-specific transcriptional changes were detected for genes involved in dna damage response and apoptosis (upregulation of gadd 153, gadd 45, annexin v), response to oxidative stress (differential expression of hypoxia-inducible factor 1 and catalase), and inflammatory reactions (upregulation of alpha 2 macroglobulin, ceruloplasmin, and cathepsin s). |
2003-12-10 |
2023-08-12 |
rat |
| Paolo Puddu, Giovanni M Puddu, Antonio Muscar. Peroxisome proliferator-activated receptors: are they involved in atherosclerosis progression? International journal of cardiology. vol 90. issue 2-3. 2003-12-09. PMID:12957742. |
ppar alpha and gamma are the two main categories of these receptors, which are both characterized by their ability to influence lipid metabolism, glucose homeostasis, cell proliferation, differentiation and apoptosis, as well as the inflammatory response, by transcriptional activation of target genes. |
2003-12-09 |
2023-08-12 |
Not clear |
| H Nakae, Y-J Zheng, H Wada, K Tajimi, S End. Involvement of IL-18 and soluble fas in patients with postoperative hepatic failure. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. vol 35. issue 2. 2003-12-05. PMID:12679613. |
we measured the levels of tumor necrosis factor alpha (tnf-alpha), interleukins (il)-6 and -18, and soluble fas (sfas) in 11 patients with postoperative hepatic failure and assessed whether il-18-mediated apoptosis is involved in the onset of liver dysfunction. |
2003-12-05 |
2023-08-12 |
Not clear |
| Amy L Howes, Jane F Arthur, Tong Zhang, Shigeki Miyamoto, John W Adams, Gerald W Dorn, Elizabeth A Woodcock, Joan Heller Brow. Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion. The Journal of biological chemistry. vol 278. issue 41. 2003-12-02. PMID:12900409. |
expression of the wild type alpha subunit of gq (gqwt) in cardiomyocytes induces hypertrophy, whereas a constitutively active g alpha q subunit (gqq209l) induces apoptosis. |
2003-12-02 |
2023-08-12 |
mouse |
| Amy L Howes, Jane F Arthur, Tong Zhang, Shigeki Miyamoto, John W Adams, Gerald W Dorn, Elizabeth A Woodcock, Joan Heller Brow. Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion. The Journal of biological chemistry. vol 278. issue 41. 2003-12-02. PMID:12900409. |
in transgenic mice with cardiac g alpha q overexpression, heart failure and increased cardiomyocyte apoptosis develop during the peripartal period. |
2003-12-02 |
2023-08-12 |
mouse |
| K Sato, U Aytac, T Yamochi, T Yamochi, K Ohnuma, K S McKee, C Morimoto, N H Dan. CD26/dipeptidyl peptidase IV enhances expression of topoisomerase II alpha and sensitivity to apoptosis induced by topoisomerase II inhibitors. British journal of cancer. vol 89. issue 7. 2003-11-25. PMID:14520473. |
cd26/dipeptidyl peptidase iv enhances expression of topoisomerase ii alpha and sensitivity to apoptosis induced by topoisomerase ii inhibitors. |
2003-11-25 |
2023-08-12 |
Not clear |
| R Sasson, A Amsterda. Pleiotropic anti-apoptotic activity of glucocorticoids in ovarian follicular cells. Biochemical pharmacology. vol 66. issue 8. 2003-11-20. PMID:14555213. |
glucocorticoids (gc) such as hydrocortisone and dexamethasone (dex) protect steroidogenic granulosa cells against apoptosis induced by serum deprivation, camp, tumor necrosis factor alpha stimulation or p53 activation. |
2003-11-20 |
2023-08-12 |
human |