Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Meagan J Walsh, Daina M Vanags, Andrew D Clouston, Michelle M Richardson, David M Purdie, Julie R Jonsson, Elizabeth E Powel. Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury. Hepatology (Baltimore, Md.). vol 39. issue 5. 2004-05-24. PMID:15122751. |
we studied 125 patients with chronic hepatitis c to assess the effect of steatosis on liver cell apoptosis and the expression of bcl-2, bcl-x(l), bax, and tumor necrosis factor alpha (tnf-alpha) and the relationship between liver cell apoptosis and disease severity. |
2004-05-24 |
2023-08-12 |
Not clear |
Chiarella Bozzo, Grazia Lombardi, Claudio Santoro, Pier Luigi Canonic. Involvement of beta(1) integrin in betaAP-induced apoptosis in human neuroblastoma cells. Molecular and cellular neurosciences. vol 25. issue 1. 2004-05-19. PMID:14962735. |
this protective effect seems to be mediated by integrins, because preincubation of neuroblastoma cells with antibodies directed against beta(1) and alpha(1) integrin subunits greatly enhanced betaap-induced apoptosis. |
2004-05-19 |
2023-08-12 |
human |
Zhi-Xiang Shen, Zhan-Zhong Shi, Jing Fang, Bai-Wei Gu, Jun-Min Li, Yong-Mei Zhu, Jing-Yi Shi, Pei-Zheng Zheng, Hua Yan, Yuan-Fang Liu, Yu Chen, Yang Shen, Wen Wu, Wei Tang, Samuel Waxman, Hugues De Thé, Zhen-Yi Wang, Sai-Juan Chen, Zhu Che. All-trans retinoic acid/As2O3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 15. 2004-05-19. PMID:15044693. |
synergism of atra and as(2)o(3) on apoptosis and degradation of pml-rar alpha oncoprotein might provide a plausible explanation for superior efficacy of combination therapy in clinic. |
2004-05-19 |
2023-08-12 |
human |
J O'Sullivan, L Whyte, J Drake, M Tenniswoo. Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis. Cell death and differentiation. vol 10. issue 8. 2004-05-05. PMID:12867999. |
these studies describe the biogenesis and intracellular trafficking of clusterin in mcf-7 cells before and after the initiation of apoptosis with antiestrogens and tnf alpha. |
2004-05-05 |
2023-08-12 |
Not clear |
Stephen J Turner, Nicole L La Gruta, John Stambas, Gabriela Diaz, Peter C Dohert. Differential tumor necrosis factor receptor 2-mediated editing of virus-specific CD8+ effector T cells. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 10. 2004-05-05. PMID:14993609. |
the d(b)pa(224)-specific cd8(+) effector t cells make more tumor necrosis factor (tnf) alpha than the comparable cd8(+)d(b)np(366)(+) set, a difference reflected in the greater sensitivity of the cd8(+)d(b)pa(224)(+) population to tnf receptor (tnfr) 2-mediated apoptosis under conditions of in vitro culture. |
2004-05-05 |
2023-08-12 |
mouse |
Gunda Aparna, Abani K Bhuyan, Sudhir Sahdev, Seyed E Hasnain, Randal J Kaufman, Kolluru V A Ramaia. Stress-induced apoptosis in Spodoptera frugiperda (Sf9) cells: baculovirus p35 mitigates eIF2 alpha phosphorylation. Biochemistry. vol 42. issue 51. 2004-05-04. PMID:14690445. |
stress-induced apoptosis in spodoptera frugiperda (sf9) cells: baculovirus p35 mitigates eif2 alpha phosphorylation. |
2004-05-04 |
2023-08-12 |
human |
Gunda Aparna, Abani K Bhuyan, Sudhir Sahdev, Seyed E Hasnain, Randal J Kaufman, Kolluru V A Ramaia. Stress-induced apoptosis in Spodoptera frugiperda (Sf9) cells: baculovirus p35 mitigates eIF2 alpha phosphorylation. Biochemistry. vol 42. issue 51. 2004-05-04. PMID:14690445. |
we report that uninfected sf9 cells readily undergo apoptosis and show increased phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eif2alpha) in the presence of agents such as uvb light, etoposide, high concentrations of cycloheximide, and egta. |
2004-05-04 |
2023-08-12 |
human |
L M M Albuquerque, A B Garcia, J O Mengel, R P Falcão, M de Castro, E M Reg. The higher expression of alpha and beta isoforms of the human glucocorticoid receptor in leukemic B-progenitors compared to normal CD10+ BM cells does not correlate with methylprednisolone-induced apoptosis. Leukemia. vol 18. issue 4. 2004-05-03. PMID:14973507. |
the higher expression of alpha and beta isoforms of the human glucocorticoid receptor in leukemic b-progenitors compared to normal cd10+ bm cells does not correlate with methylprednisolone-induced apoptosis. |
2004-05-03 |
2023-08-12 |
human |
J Du, G G Chen, A C Vlantis, P K S Chan, R K Y Tsang, C A van Hassel. Resistance to apoptosis of HPV 16-infected laryngeal cancer cells is associated with decreased Bak and increased Bcl-2 expression. Cancer letters. vol 205. issue 1. 2004-04-28. PMID:15036664. |
using these two cell lines, we found that both e6 and e7 exhibited an inhibitive effect on apoptosis induced by tumor necrosis factor alpha and cycloheximide. |
2004-04-28 |
2023-08-12 |
human |
Ingrid G Winkler, Karen R Snapp, Paul J Simmons, Jean-Pierre Lévesqu. Adhesion to E-selectin promotes growth inhibition and apoptosis of human and murine hematopoietic progenitor cells independent of PSGL-1. Blood. vol 103. issue 5. 2004-04-20. PMID:14592840. |
moreover, stable transfection of the human myeloid cell line k562 (which does not express psgl-1) with alpha(1,3) fucosyltransferase vii alone was sufficient to recapitulate the e-selectin-mediated growth inhibition and apoptosis observed in hematopoietic progenitor cells. |
2004-04-20 |
2023-08-12 |
mouse |
Jianxin Wu, Bei-Bei Zhu, Jin Yu, Hong Zhu, Lu Qiu, Mark S Kindy, Liya Gu, Albrecht Seidel, Guo-Min L. In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system. Nucleic acids research. vol 31. issue 22. 2004-04-16. PMID:14602900. |
cell lines proficient in mmr exhibited several-fold more sensitivity to killing than cell lines defective in either muts(alpha) or mutl(alpha) by b[c]phde; the nature of this sensitivity was shown to be due to increased apoptosis. |
2004-04-16 |
2023-08-12 |
mouse |
Nicole Maas-Szabowski, Anja Stärker, Norbert E Fuseni. Epidermal tissue regeneration and stromal interaction in HaCaT cells is initiated by TGF-alpha. Journal of cell science. vol 116. issue Pt 14. 2004-04-07. PMID:12771184. |
addition of tgf- alpha or egf stimulated hacat cell proliferation but, even more effectively, suppressed apoptosis, thus facilitating the formation of a regularly stratified epithelium. |
2004-04-07 |
2023-08-12 |
mouse |
Nhan Trung Nguyen, Arjun H Banskota, Yasuhiro Tezuka, Quan Le Tran, Takahiro Nobukawa, Youichi Kurashige, Masakiyo Sasahara, Shigetoshi Kadot. Hepatoprotective effect of taxiresinol and (7'R)-7'-hydroxylariciresinol on D-galactosamine and lipopolysaccharide-induced liver injury in mice. Planta medica. vol 70. issue 1. 2004-03-30. PMID:14765289. |
these results suggested that 1 and 2 had protected the hepatocytes from apoptosis via an inhibition of tnf- alpha production by activated macrophages and a direct inhibition of apoptosis induced by tnf- alpha in d-galn/lps-treated mice. |
2004-03-30 |
2023-08-12 |
mouse |
Emily J Foulstone, Camille Huser, Anna L Crown, Jeff M P Holly, Claire E H Stewar. Differential signalling mechanisms predisposing primary human skeletal muscle cells to altered proliferation and differentiation: roles of IGF-I and TNFalpha. Experimental cell research. vol 294. issue 1. 2004-03-30. PMID:14980516. |
stimulation with both igf-i and tumour necrosis factor alpha (tnfalpha) increased cellular proliferation but while igf-i subsequently increased myoblast differentiation, via both hyperplasia and hypertrophy, tnfalpha inhibited the initiation of differentiation, but did not induce apoptosis. |
2004-03-30 |
2023-08-12 |
human |
Adrian A Lobito, Marcela F Lopes, Michael J Lenard. Ectopic T cell receptor expression causes B cell immunodeficiency in transgenic mice. European journal of immunology. vol 34. issue 3. 2004-03-25. PMID:14991619. |
we now show data suggesting that this defect is due to the expression and accumulation of tcr alpha and beta chains inside b cells and induction of an endoplasmic reticulum stress response, causing apoptosis at the pre b-i and later b cell stage. |
2004-03-25 |
2023-08-12 |
mouse |
Elizabeth J Horn, Amador Albor, Yuangang Liu, Sally El-Hizawi, Gretchen E Vanderbeek, Melissa Babcock, G Tim Bowden, Henry Hennings, Guillermina Lozano, Wendy C Weinberg, Molly Kulesz-Marti. RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties. Carcinogenesis. vol 25. issue 2. 2004-03-17. PMID:14578165. |
however, transduced trim32 inhibited the synergistic effect of tumor necrosis factor alpha (tnfalpha) on uvb-induced apoptosis of keratinocytes in vitro and the apoptotic response of keratinocyte grafts exposed to uvb-light in vivo. |
2004-03-17 |
2023-08-12 |
mouse |
Vladimir Vukicevic, Katja Kampfinger, Helga Stoppe. Influence of altered apoptosis in human lymphoblastoid cell lines on micronucleus frequency. Toxicology letters. vol 147. issue 2. 2004-03-16. PMID:14757322. |
apoptosis was reduced by the addition of pifithrin (pft) alpha and enhanced by transient transfection with bcl-2 antisense-oligonucleotide in bcl-2-overexpressing cells. |
2004-03-16 |
2023-08-12 |
human |
Zhiyan Wang, Kazuhiro Tamura, Mikihiro Yoshie, Hiroshi Tamura, Kazuhiko Imakawa, Hiroshi Kog. Prostaglandin F2alpha-induced functional regression of the corpus luteum and apoptosis in rodents. Journal of pharmacological sciences. vol 92. issue 1. 2004-03-11. PMID:12832851. |
we investigated the relationship between prostaglandin (pg) f(2)(alpha)-induced functional luteal regression and apoptosis in the rodent ovary. |
2004-03-11 |
2023-08-12 |
mouse |
Magdalena Rechnio, Bogumiła Litwińsk. Differences in inhibition of apoptosis depending on the virulence of used herpes simplex virus type 1 strains. Function of interferon alpha in apoptotic death of virus infected cells. Acta microbiologica Polonica. vol 52. issue 3. 2004-03-04. PMID:14743979. |
all strains of hsv-1 didn't inhibit apoptosis in the presence of ifn alpha and apoptosis was inhibited by anti ifn alpha antibodies. |
2004-03-04 |
2023-08-12 |
mouse |
James D Firth, Edward E Putnin. Keratinocyte growth factor 1 inhibits wound edge epithelial cell apoptosis in vitro. The Journal of investigative dermatology. vol 122. issue 1. 2004-03-04. PMID:14962112. |
tumor necrosis factor alpha (1-5 ng per ml) or escherichia coli lipopolysaccharide (10-50 ng per ml) exacerbated scrape-induced early apoptosis (1-4 h), but was largely ameliorated by coculture with keratinocyte growth factor 1. |
2004-03-04 |
2023-08-12 |
Not clear |