| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Bauernhofer, I Kuss, U Friebe-Hoffmann, A S Baum, G Dworacki, B K Vonderhaar, T L Whitesid. Role of prolactin receptor and CD25 in protection of circulating T lymphocytes from apoptosis in patients with breast cancer. British journal of cancer. vol 88. issue 8. 2004-11-16. PMID:12698200. |
we investigated a possible relation between prolactin receptor (prl-r) or il-2 receptor alpha (il-2ralpha, cd25) expression on circulating t lymphocytes and their apoptosis in patients with breast cancer. |
2004-11-16 |
2023-08-12 |
Not clear |
| C M Payne, C N Waltmire, C Crowley, C L Crowley-Weber, K Dvorakova, H Bernstein, C Bernstein, H Holubec, H Garewa. Caspase-6 mediated cleavage of guanylate cyclase alpha 1 during deoxycholate-induced apoptosis: protective role of the nitric oxide signaling module. Cell biology and toxicology. vol 19. issue 6. 2004-11-12. PMID:15015762. |
caspase-6 mediated cleavage of guanylate cyclase alpha 1 during deoxycholate-induced apoptosis: protective role of the nitric oxide signaling module. |
2004-11-12 |
2023-08-12 |
Not clear |
| C M Payne, C N Waltmire, C Crowley, C L Crowley-Weber, K Dvorakova, H Bernstein, C Bernstein, H Holubec, H Garewa. Caspase-6 mediated cleavage of guanylate cyclase alpha 1 during deoxycholate-induced apoptosis: protective role of the nitric oxide signaling module. Cell biology and toxicology. vol 19. issue 6. 2004-11-12. PMID:15015762. |
a novel finding from this study is the caspase-6 mediated cleavage of guanylate cyclase alpha 1 during deoxycholate-induced apoptosis of deoxycholate-sensitive hct-116sa cells and the absence of guanylate cyclase alpha 1 cleavage in deoxycholate-treated hct-116r resistant cells using western blot analyses. |
2004-11-12 |
2023-08-12 |
Not clear |
| Chunhua Qin, Derek Morrow, Jessica Stewart, Kyle Spencer, Weston Porter, Roger Smith, Timothy Phillips, Maen Abdelrahim, Ismael Samudio, Stephen Saf. A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes. Molecular cancer therapeutics. vol 3. issue 3. 2004-11-09. PMID:15026545. |
c-substituted diindolylmethanes inhibit carcinogen-induced rat mammary tumor growth, induce differentiation in 3t3-l1 preadipocytes, inhibit mcf-7 cell growth and g(0)/g(1)-s phase progression, induce apoptosis, and down-regulate cyclin d1 protein and estrogen receptor alpha in breast cancer cells. |
2004-11-09 |
2023-08-12 |
rat |
| b' E D Bazhanova, D L Teply\\xc4\\xa. [Role of alpha-interferon in regulation of apoptosis in cells of the hypothalamo-hypophyseal-adrenocortical system of old mice in oxidative stress]. Morfologiia (Saint Petersburg, Russia). vol 125. issue 1. 2004-11-09. PMID:15083573.' |
the aim of this work was to demonstrate the role of interferon alpha (ia) in apoptosis control of cells of hypothalamohypophysial adrenocortical system (hhas) in young and old mice under conditions of hyperoxia. |
2004-11-09 |
2023-08-12 |
mouse |
| Karin Schmelz, Thomas Wieder, Ingo Tamm, Antje Müller, Frank Essmann, Christoph-C Geilen, Klaus Schulze-Osthoff, Bernd Dörken, Peter-T Danie. Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB. Oncogene. vol 23. issue 40. 2004-10-29. PMID:15273737. |
tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and nf-kappab. |
2004-10-29 |
2023-08-12 |
Not clear |
| Karin Schmelz, Thomas Wieder, Ingo Tamm, Antje Müller, Frank Essmann, Christoph-C Geilen, Klaus Schulze-Osthoff, Bernd Dörken, Peter-T Danie. Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB. Oncogene. vol 23. issue 40. 2004-10-29. PMID:15273737. |
the hodgkin cell line hd-myz is resistant to apoptosis induced by tumor necrosis factor alpha (tnfalpha). |
2004-10-29 |
2023-08-12 |
Not clear |
| Almudena Porras, Susana Zuluaga, Emma Black, Amparo Valladares, Alberto M Alvarez, Concetta Ambrosino, Manuel Benito, Angel R Nebred. P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Molecular biology of the cell. vol 15. issue 2. 2004-10-27. PMID:14617800. |
p38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. |
2004-10-27 |
2023-08-12 |
mouse |
| Almudena Porras, Susana Zuluaga, Emma Black, Amparo Valladares, Alberto M Alvarez, Concetta Ambrosino, Manuel Benito, Angel R Nebred. P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Molecular biology of the cell. vol 15. issue 2. 2004-10-27. PMID:14617800. |
we have used cell lines derived from p38 alpha knockout mice to study the role of this signaling pathway in the regulation of apoptosis. |
2004-10-27 |
2023-08-12 |
mouse |
| Almudena Porras, Susana Zuluaga, Emma Black, Amparo Valladares, Alberto M Alvarez, Concetta Ambrosino, Manuel Benito, Angel R Nebred. P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Molecular biology of the cell. vol 15. issue 2. 2004-10-27. PMID:14617800. |
here, we show that cardiomyocytes and fibroblasts lacking p38 alpha are more resistant to apoptosis induced by different stimuli. |
2004-10-27 |
2023-08-12 |
mouse |
| Almudena Porras, Susana Zuluaga, Emma Black, Amparo Valladares, Alberto M Alvarez, Concetta Ambrosino, Manuel Benito, Angel R Nebred. P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Molecular biology of the cell. vol 15. issue 2. 2004-10-27. PMID:14617800. |
cells lacking p38 alpha also have increased extracellular signal-regulated kinase (erks) map kinase activity, and the up-regulation of this survival pathway seems to be at least partially responsible for the reduced levels of apoptosis in the absence of p38 alpha. |
2004-10-27 |
2023-08-12 |
mouse |
| Almudena Porras, Susana Zuluaga, Emma Black, Amparo Valladares, Alberto M Alvarez, Concetta Ambrosino, Manuel Benito, Angel R Nebred. P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli. Molecular biology of the cell. vol 15. issue 2. 2004-10-27. PMID:14617800. |
thus, p38 alpha seems to sensitize cells to apoptosis via both up-regulation of proapoptotic proteins and down-regulation of survival pathways. |
2004-10-27 |
2023-08-12 |
mouse |
| Anastasios Tahmatzopoulos, Randall G Rowland, Natasha Kypriano. The role of alpha-blockers in the management of prostate cancer. Expert opinion on pharmacotherapy. vol 5. issue 6. 2004-10-21. PMID:15163273. |
quinazoline-based alpha(1)-blockers have been shown to have antitumour efficacy against prostate cancer cells in inducing apoptosis and anoikis via an alpha(1)-adrenoceptor-independent mechanism. |
2004-10-21 |
2023-08-12 |
Not clear |
| Pamela Cameron, Susan J Smith, Mark A Giembycz, Dino Rotondo, Robin Plevi. Verotoxin activates mitogen-activated protein kinase in human peripheral blood monocytes: role in apoptosis and proinflammatory cytokine release. British journal of pharmacology. vol 140. issue 7. 2004-10-13. PMID:14597601. |
in this study, we examined the role of mitogen-activated protein (map) kinases in the effects of verotoxins (vts), from escherichia coli o157:h7, upon both apoptosis and the release of tumour necrosis factor alpha (tnf-alpha) and granulocyte-macrophage colony-stimulated factor (gm-csf) from human monocytes. |
2004-10-13 |
2023-08-12 |
human |
| Luc-Marie Gerland, Laurent Genestier, Simone Peyrol, Marie-Cécile Michallet, Sandrine Hayette, Iwona Urbanowicz, Patrick Ffrench, Jean-Pierre Magaud, Martine Ffrenc. Autolysosomes accumulate during in vitro CD8+ T-lymphocyte aging and may participate in induced death sensitization of senescent cells. Experimental gerontology. vol 39. issue 5. 2004-10-05. PMID:15130673. |
cell death following stimulations: (i) corresponded to apoptosis, associated with necrosis at the end of the culture; (ii) was not, for its main part, mediated through cd95/cd178 or tnfrii/tnf alpha interactions; and (iii) occurred in spite of bcl-2 increased expression. |
2004-10-05 |
2023-08-12 |
Not clear |
| Simone Grethe, Mikko P S Ares, Tommy Andersson, M Isabella Pörn-Are. p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L). Experimental cell research. vol 298. issue 2. 2004-10-04. PMID:15265709. |
here, we investigated the involvement of p38 mapk in endothelial apoptosis induced by tumor necrosis factor alpha (tnf). |
2004-10-04 |
2023-08-12 |
Not clear |
| S Zeissig, C Bojarski, N Buergel, J Mankertz, M Zeitz, M Fromm, J D Schulzk. Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor alpha antibody treatment. Gut. vol 53. issue 9. 2004-10-04. PMID:15306588. |
downregulation of epithelial apoptosis and barrier repair in active crohn's disease by tumour necrosis factor alpha antibody treatment. |
2004-10-04 |
2023-08-12 |
Not clear |
| Lin Li, Ranny Mathew Thomas, Hidetaka Suzuki, Jef K De Brabander, Xiaodong Wang, Patrick G Harra. A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death. Science (New York, N.Y.). vol 305. issue 5689. 2004-10-04. PMID:15353805. |
the compound binds to x chromosome- encoded iap (xiap), cellular iap 1 (ciap-1), and cellular iap 2 (ciap-2) and synergizes with both tumor necrosis factor alpha (tnfalpha) and tnf-related apoptosis-inducing ligand (trail) to potently induce caspase activation and apoptosis in human cancer cells. |
2004-10-04 |
2023-08-12 |
human |
| Mercedes Alemán, Pablo Schierloh, Silvia S de la Barrera, Rosa M Musella, María A Saab, Matías Baldini, Eduardo Abbate, María C Sasiai. Mycobacterium tuberculosis triggers apoptosis in peripheral neutrophils involving toll-like receptor 2 and p38 mitogen protein kinase in tuberculosis patients. Infection and immunity. vol 72. issue 9. 2004-09-24. PMID:15322009. |
we demonstrate that apoptosis of pmn is not induced by lipoarabinomannan or by a whole-cell lysate of m. tuberculosis and that neither tumor necrosis factor alpha nor cd11b, cd14, and fcgamma receptors are involved. |
2004-09-24 |
2023-08-12 |
Not clear |
| Tomohiro Banno, Alix Gazel, Miroslav Blumenber. Effects of tumor necrosis factor-alpha (TNF alpha) in epidermal keratinocytes revealed using global transcriptional profiling. The Journal of biological chemistry. vol 279. issue 31. 2004-09-10. PMID:15145954. |
we found that tnf alpha regulates not only immune and inflammatory responses but also tissue remodeling, cell motility, cell cycle, and apoptosis. |
2004-09-10 |
2023-08-12 |
human |