| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesco Pacifico, Claudio Mauro, Ciro Barone, Elvira Crescenzi, Stefano Mellone, Mario Monaco, Gennaro Chiappetta, Giuseppe Terrazzano, Domenico Liguoro, Pasquale Vito, Eduardo Consiglio, Silvestro Formisano, Antonio Leonard. Oncogenic and anti-apoptotic activity of NF-kappa B in human thyroid carcinomas. The Journal of biological chemistry. vol 279. issue 52. 2005-03-14. PMID:15475567. |
stable expression of a super-repressor form of i kappa b alpha (i kappa b alpha m) in the utc cell line fro results in enhanced sensitivity to drug-induced apoptosis, to the loss of the ability of these cells to form colonies in soft agar, and to induce tumor growth in nude mice. |
2005-03-14 |
2023-08-12 |
mouse |
| Francesco Pacifico, Claudio Mauro, Ciro Barone, Elvira Crescenzi, Stefano Mellone, Mario Monaco, Gennaro Chiappetta, Giuseppe Terrazzano, Domenico Liguoro, Pasquale Vito, Eduardo Consiglio, Silvestro Formisano, Antonio Leonard. Oncogenic and anti-apoptotic activity of NF-kappa B in human thyroid carcinomas. The Journal of biological chemistry. vol 279. issue 52. 2005-03-14. PMID:15475567. |
moreover, inhibition of jnk activity renders fro-i kappa b alpha m clones resistant to apoptosis induced by chemotherapeutic agents. |
2005-03-14 |
2023-08-12 |
mouse |
| Dalit May, Ahuva Itin, Oded Gal, Hagar Kalinski, Elena Feinstein, Eli Keshe. Ero1-L alpha plays a key role in a HIF-1-mediated pathway to improve disulfide bond formation and VEGF secretion under hypoxia: implication for cancer. Oncogene. vol 24. issue 6. 2005-03-02. PMID:15592500. |
to establish a physiological relevance to modulations in ero1-l alpha levels, we showed that even a modest, two- to three-fold reduction in ero1-l alpha production via sirna leads to significant inhibition of vegf secretion, a compromised proliferation capacity and enhanced apoptosis. |
2005-03-02 |
2023-08-12 |
human |
| Kwang S Suh, Michihiro Mutoh, Michael Gerdes, John M Crutchley, Tomoko Mutoh, Lindsay E Edwards, Rebecca A Dumont, Pooja Sodha, Christina Cheng, Adam Glick, Stuart H Yusp. Antisense suppression of the chloride intracellular channel family induces apoptosis, enhances tumor necrosis factor {alpha}-induced apoptosis, and inhibits tumor growth. Cancer research. vol 65. issue 2. 2005-03-02. PMID:15695400. |
antisense suppression of the chloride intracellular channel family induces apoptosis, enhances tumor necrosis factor {alpha}-induced apoptosis, and inhibits tumor growth. |
2005-03-02 |
2023-08-12 |
mouse |
| Kwang S Suh, Michihiro Mutoh, Michael Gerdes, John M Crutchley, Tomoko Mutoh, Lindsay E Edwards, Rebecca A Dumont, Pooja Sodha, Christina Cheng, Adam Glick, Stuart H Yusp. Antisense suppression of the chloride intracellular channel family induces apoptosis, enhances tumor necrosis factor {alpha}-induced apoptosis, and inhibits tumor growth. Cancer research. vol 65. issue 2. 2005-03-02. PMID:15695400. |
mtclic/clic4 is a p53 and tumor necrosis factor alpha (tnfalpha) regulated intracellular chloride channel protein that localizes to cytoplasm and organelles and induces apoptosis when overexpressed in several cell types of mouse and human origin. |
2005-03-02 |
2023-08-12 |
mouse |
| Dong Yin, Hong Zhou, Takashi Kumagai, Gentao Liu, John M Ong, Keith L Black, H Phillip Koeffle. Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM). Oncogene. vol 24. issue 3. 2005-03-01. PMID:15531918. |
also, ps-341 enhanced trail (tnf-related apoptosis-inducing ligand) and tnfalpha (tumor necrosis factor alpha) induced cell death and apoptosis (two- to five-fold) in gbm cells. |
2005-03-01 |
2023-08-12 |
human |
| Yongbao Wang, Bo Wang, Jinchun Cheng, Li Yang, Zhong-Li Liu, Kannan Balan, Panayotis Pantazis, James H Wyche, Zhiyong Ha. FADD-dependent apoptosis induction in Jurkat leukemia T-cells by the resveratrol analogue, 3,4,5-trihydroxy-trans-stilbene. Biochemical pharmacology. vol 69. issue 2. 2005-02-18. PMID:15627477. |
indeed, we found that treatment of jurkat cells with 3,4,5-ths, unlike treatment with resveratrol, induced activation of caspase-8 and apoptosis by a fas-associated death domain (fadd) protein-dependent mechanism without involving the known death ligands cd95 ligand (cd95l), tumor necrosis factor alpha (tnfalpha) and tnf-related apoptosis-inducing ligand (trail). |
2005-02-18 |
2023-08-12 |
human |
| L F Bonewal. Osteocyte biology: its implications for osteoporosis. Journal of musculoskeletal & neuronal interactions. vol 4. issue 1. 2005-02-17. PMID:15615083. |
cd40ligand protects osteoblasts and the mlo-y4 osteocyte-like cells against apoptosis induced by glucocorticoids, tumor necrosis factor alpha or etoposide. |
2005-02-17 |
2023-08-12 |
human |
| Chiara Porta, Reda Hadj-Slimane, Mohamed Nejmeddine, Mathieu Pampin, Michael G Tovey, Lucile Espert, Sandra Alvarez, Mounira K Chelbi-Ali. Interferons alpha and gamma induce p53-dependent and p53-independent apoptosis, respectively. Oncogene. vol 24. issue 4. 2005-02-15. PMID:15580300. |
interferons alpha and gamma induce p53-dependent and p53-independent apoptosis, respectively. |
2005-02-15 |
2023-08-12 |
Not clear |
| Vladimir N Ivanov, Tom K He. Combined treatment with EGFR inhibitors and arsenite upregulated apoptosis in human EGFR-positive melanomas: a role of suppression of the PI3K-AKT pathway. Oncogene. vol 24. issue 4. 2005-02-15. PMID:15580309. |
under these conditions, metastatic melanoma cell lines undergo tnf-related apoptosis-inducing ligand (trail)- and tumor necrosis factor alpha (tnfalpha)-mediated apoptosis. |
2005-02-15 |
2023-08-12 |
human |
| Martijn Schenning, Claudia M van Tiel, Daniëlle Van Manen, Jord C Stam, Barend M Gadella, Karel W A Wirtz, Gerry T Snoe. Phosphatidylinositol transfer protein alpha regulates growth and apoptosis of NIH3T3 cells: involvement of a cannabinoid 1-like receptor. Journal of lipid research. vol 45. issue 8. 2005-02-08. PMID:15145975. |
phosphatidylinositol transfer protein alpha regulates growth and apoptosis of nih3t3 cells: involvement of a cannabinoid 1-like receptor. |
2005-02-08 |
2023-08-12 |
mouse |
| Martijn Schenning, Claudia M van Tiel, Daniëlle Van Manen, Jord C Stam, Barend M Gadella, Karel W A Wirtz, Gerry T Snoe. Phosphatidylinositol transfer protein alpha regulates growth and apoptosis of NIH3T3 cells: involvement of a cannabinoid 1-like receptor. Journal of lipid research. vol 45. issue 8. 2005-02-08. PMID:15145975. |
mouse fibroblast cells overexpressing phosphatidylinositol transfer protein alpha [pi-tpalpha; sense pi-tpalpha (spialpha) cells] show a significantly increased rate of proliferation and an extreme resistance toward ultraviolet- or tumor necrosis factor-alpha-induced apoptosis. |
2005-02-08 |
2023-08-12 |
mouse |
| Yogesh C Awasthi, Yusong Yang, Narendra K Tiwari, Brad Patrick, Abha Sharma, Jie Li, Sanjay Awasth. Regulation of 4-hydroxynonenal-mediated signaling by glutathione S-transferases. Free radical biology & medicine. vol 37. issue 5. 2005-02-08. PMID:15288119. |
we have recently demonstrated that overexpression of the alpha class gsts in cells leads to lower steady-state levels of hne, and these cells acquire resistance to apoptosis induced by lipid peroxidation-causing agents such as h(2)o(2), uva, superoxide anion, and pro-oxidant xenobiotics, suggesting that signaling for apoptosis by these agents is transduced through hne. |
2005-02-08 |
2023-08-12 |
Not clear |
| Satoko Fujihara, Ellis Jaffray, Stuart N Farrow, Adriano G Rossi, Christopher Haslett, Ronald T Ha. Inhibition of NF-kappa B by a cell permeable form of I kappa B alpha induces apoptosis in eosinophils. Biochemical and biophysical research communications. vol 326. issue 3. 2005-01-31. PMID:15596146. |
inhibition of nf-kappa b by a cell permeable form of i kappa b alpha induces apoptosis in eosinophils. |
2005-01-31 |
2023-08-12 |
human |
| Satoko Fujihara, Ellis Jaffray, Stuart N Farrow, Adriano G Rossi, Christopher Haslett, Ronald T Ha. Inhibition of NF-kappa B by a cell permeable form of I kappa B alpha induces apoptosis in eosinophils. Biochemical and biophysical research communications. vol 326. issue 3. 2005-01-31. PMID:15596146. |
introduction of tat-i kappa b alpha(s32a, s36a) into human eosinophils inhibited the nuclear translocation of nf-kappa b and induced apoptosis. |
2005-01-31 |
2023-08-12 |
human |
| Yang Wang, Tamara Mink. A novel cancer therapy: combined liposomal hypoxia inducible factor 1 alpha antisense oligonucleotides and an anticancer drug. Biochemical pharmacology. vol 68. issue 10. 2005-01-25. PMID:15476674. |
the combined influence of doxorubicin (dox) and liposomal antisense oligonucleotides (asos) targeted to hypoxia-inducible factor 1 alpha (hif1a) subunit on the apoptosis signaling pathways and cellular pump and nonpump resistance were investigated. |
2005-01-25 |
2023-08-12 |
human |
| Yan Zhang, Hai Lu, Paul Dazin, Yvonne Kapil. Squamous cell carcinoma cell aggregates escape suspension-induced, p53-mediated anoikis: fibronectin and integrin alphav mediate survival signals through focal adhesion kinase. The Journal of biological chemistry. vol 279. issue 46. 2005-01-21. PMID:15331608. |
blocking alpha(v) function with a blocking antibody or by transfection with an antisense oligonucleotide increased apoptosis and inhibited aggregation. |
2005-01-21 |
2023-08-12 |
human |
| Tadeusz-Wojciech Lapinski, Oksana Kowalczuk, Danuta Prokopowicz, Lech Chyczewsk. Serum concentration of sFas and sFasL in healthy HBsAg carriers, chronic viral hepatitis B and C patients. World journal of gastroenterology. vol 10. issue 24. 2005-01-19. PMID:15534924. |
to estimate the amount of apoptosis among healthy hbsag carriers, patients with chronic hbv infection treated with lamivudine and patients with chronic hcv infection treated with interferon alpha and ribavirin. |
2005-01-19 |
2023-08-12 |
Not clear |
| I Lamote, E Meyer, A M Massart-Leën, C Burvenic. Sex steroids and growth factors in the regulation of mammary gland proliferation, differentiation, and involution. Steroids. vol 69. issue 3. 2005-01-14. PMID:15072917. |
another important regulatory role is played by growth factors that have been shown to modulate survival (epidermal growth factor, amphiregulin, transforming growth factor alpha, insulin like growth factor, and tumor necrosis factor alpha) or apoptosis (tumor necrosis factor alpha, transforming growth factor beta) of mammary cells. |
2005-01-14 |
2023-08-12 |
Not clear |
| Shaochun Bai, Hongtao Liu, Kun-Hung Chen, Polikseni Eksarko, Harris Perlman, Terry L Moore, Richard M Pop. NF-kappaB-regulated expression of cellular FLIP protects rheumatoid arthritis synovial fibroblasts from tumor necrosis factor alpha-mediated apoptosis. Arthritis and rheumatism. vol 50. issue 12. 2005-01-13. PMID:15593196. |
tumor necrosis factor alpha (tnfalpha) is expressed in the joints of patients with ra, yet ra synovial fibroblasts are relatively resistant to apoptosis induced by tnfalpha. |
2005-01-13 |
2023-08-12 |
Not clear |