| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Todd R Flower, Liudmila S Chesnokova, Clifford A Froelich, Cheryl Dixon, Stephan N Wit. Heat shock prevents alpha-synuclein-induced apoptosis in a yeast model of Parkinson's disease. Journal of molecular biology. vol 351. issue 5. 2005-09-19. PMID:16051265. |
we show that human wild-type alpha synuclein (wt alpha-syn), and the inherited mutants a53t or a30p, when expressed in the yeast saccharomyces cerevisiae triggers events that are diagnostic of apoptosis: loss of membrane asymmetry due to the externalization of phosphatidylserine, accumulation of reactive oxygen species (ros), and the release of cytochrome c from mitochondria. |
2005-09-19 |
2023-08-12 |
human |
| Feng Qian, Zi-Chao Zhang, Xue-Feng Wu, Yu-Pei Li, Qiang X. Interaction between integrin alpha(5) and fibronectin is required for metastasis of B16F10 melanoma cells. Biochemical and biophysical research communications. vol 333. issue 4. 2005-09-07. PMID:15979576. |
furthermore, loss of the interaction between alpha(5) and fibronectin diminished cell survival and induced apoptosis in b16f10 cells. |
2005-09-07 |
2023-08-12 |
mouse |
| Olivier Meurette, Luz Lefeuvre-Orfila, Amélie Rebillard, Dominique Lagadic-Gossmann, Marie-Thérèse Dimanche-Boitre. Role of intracellular glutathione in cell sensitivity to the apoptosis induced by tumor necrosis factor {alpha}-related apoptosis-inducing ligand/anticancer drug combinations. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 11. issue 8. 2005-08-29. PMID:15837763. |
role of intracellular glutathione in cell sensitivity to the apoptosis induced by tumor necrosis factor {alpha}-related apoptosis-inducing ligand/anticancer drug combinations. |
2005-08-29 |
2023-08-12 |
Not clear |
| Suiqiang Zhu, Zhouping Tang, Shougang Guo, Lan Peng, Siyu Fang, Suming Zhan. Experimental study on the expression of HIF-1alpha and its relationship to apoptosis in tissues around cerebral bleeding loci. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 24. issue 4. 2005-08-26. PMID:15587402. |
the expression of hypoxia inducible factor-1 alpha (hif-1alpha) and its relationship to apoptosis in tissues around cerebral bleeding loci was studied. |
2005-08-26 |
2023-08-12 |
Not clear |
| Sang-Yun Lee, Rama P Cherla, Isa Caliskan, Vernon L Tes. Shiga toxin 1 induces apoptosis in the human myelogenous leukemia cell line THP-1 by a caspase-8-dependent, tumor necrosis factor receptor-independent mechanism. Infection and immunity. vol 73. issue 8. 2005-08-26. PMID:16041028. |
here, we show that stx1 induces apoptosis in the undifferentiated myelogenous leukemia cell line thp-1 in the absence of tumor necrosis factor alpha (tnf-alpha) or death receptor (tnf receptor or fas) expression. |
2005-08-26 |
2023-08-12 |
human |
| Michelle Embree-Ku, Philip A Gruppus. The role of nuclear factor kappaB in late-gestation liver development in the rat. Hepatology (Baltimore, Md.). vol 42. issue 2. 2005-08-18. PMID:16025516. |
tumor necrosis factor alpha (tnf-alpha) administration to e19 embryos in utero produced minimal induction of nf-kappab p50 homodimers and p50/p65 heterodimers, yet baseline apoptosis was not affected. |
2005-08-18 |
2023-08-12 |
rat |
| D S A Sander. Mucosal integrity and barrier function in the pathogenesis of early lesions in Crohn's disease. Journal of clinical pathology. vol 58. issue 6. 2005-08-09. PMID:15917403. |
cytokines, such as tumour necrosis factor alpha (tnfalpha), are known to drive inflammation, but emerging data suggest additional important roles for tnfalpha influencing mucosal barrier efficacy by altering adhesion molecule expression, influencing epithelial apoptosis, and affecting tight junction functionality. |
2005-08-09 |
2023-08-12 |
Not clear |
| Haruyo Ichikawa, Yasunari Takada, Akira Murakami, Bharat B Aggarwa. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 11. 2005-08-08. PMID:15905586. |
identification of a novel blocker of i kappa b alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of nf-kappa b-regulated gene products. |
2005-08-08 |
2023-08-12 |
Not clear |
| E D Bazhanov. [Interferon alpha involvement in apoptosis regulation. ]. Zhurnal evoliutsionnoi biokhimii i fiziologii. vol 41. issue 2. 2005-08-05. PMID:15909892. |
[interferon alpha involvement in apoptosis regulation. |
2005-08-05 |
2023-08-12 |
Not clear |
| Martin Handfield, Jeffrey J Mans, Gaolin Zheng, M Cecilia Lopez, Song Mao, Ann Progulske-Fox, Giri Narasimhan, Henry V Baker, Richard J Lamon. Distinct transcriptional profiles characterize oral epithelium-microbiota interactions. Cellular microbiology. vol 7. issue 6. 2005-08-02. PMID:15888084. |
furthermore, with a. actinomycetemcomitans, the induction of apoptosis did not appear to be fas- or tnf(alpha)-mediated. |
2005-08-02 |
2023-08-12 |
human |
| B A van Adel, J M Arnold, J Phipps, L C Doering, A K Bal. Ciliary neurotrophic factor protects retinal ganglion cells from axotomy-induced apoptosis via modulation of retinal glia in vivo. Journal of neurobiology. vol 63. issue 3. 2005-07-29. PMID:15719421. |
adenoviral-mediated transfer of ciliary neurotrophic factor (cntf) to the retina rescued retinal ganglion cells (rgcs) from axotomy-induced apoptosis, presumably via activation of the high affinity cntf receptor alpha (cntfralpha) expressed on rgcs. |
2005-07-29 |
2023-08-12 |
rat |
| Jian-Gang Jiang, Chun-Lian Chen, Jeffrey W Card, Shilin Yang, Ji-Xiong Chen, Xiang-Ning Fu, Yao-Gui Ning, Xiao Xiao, Darryl C Zeldin, Dao Wen Wan. Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors. Cancer research. vol 65. issue 11. 2005-07-28. PMID:15930289. |
in addition, forced overexpression of cyp2j2, and cyp bm3f87v or addition of epoxyeicosatrienoic acids (eet) in cultured carcinoma cell lines in vitro markedly accelerated proliferation by analyses of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, cell accounts, and cell cycle analysis, and protected carcinoma cells from apoptosis induced by tumor necrosis factor alpha (tnf-alpha) in cultures. |
2005-07-28 |
2023-08-12 |
human |
| Lulu Farhana, Marcia I Dawson, Joseph A Fontan. Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kappaB activation. Cancer research. vol 65. issue 11. 2005-07-28. PMID:15930313. |
in addition, inhibition of ikappab alpha degradation using a dominant-negative ikappab alpha inhibits 3-cl-ahpc-mediated apoptosis. |
2005-07-28 |
2023-08-12 |
Not clear |
| Tomohiro Banno, Alix Gazel, Miroslav Blumenber. Pathway-specific profiling identifies the NF-kappa B-dependent tumor necrosis factor alpha-regulated genes in epidermal keratinocytes. The Journal of biological chemistry. vol 280. issue 19. 2005-07-12. PMID:15722350. |
immune response, cell cycle, and apoptosis) through several signal transduction pathways that convey the tnf alpha signals to the nucleus. |
2005-07-12 |
2023-08-12 |
human |
| John F Grehan, Brett K Levay-Young, Barbara A Benson, Mitchell S Abrahamsen, Agustin P Dalmass. Alpha Gal ligation of pig endothelial cells induces protection from complement and apoptosis independently of NF-kappa B and inflammatory changes. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. vol 5. issue 4 Pt 1. 2005-07-12. PMID:15760394. |
alpha gal ligation of pig endothelial cells induces protection from complement and apoptosis independently of nf-kappa b and inflammatory changes. |
2005-07-12 |
2023-08-12 |
human |
| Laifa Hendarmin, Ferry Sandra, Yu Nakao, Masamichi Ohishi, Norifumi Nakamur. TNFalpha played a role in induction of Akt and MAPK signals in ameloblastoma. Oral oncology. vol 41. issue 4. 2005-07-11. PMID:15792609. |
tumour necrosis factor alpha (tnfalpha) is known crucial in inducing cell survival, proliferation, differentiation, and apoptosis. |
2005-07-11 |
2023-08-12 |
Not clear |
| Kazuhiko Yamane, Timothy J Kinsell. CK2 inhibits apoptosis and changes its cellular localization following ionizing radiation. Cancer research. vol 65. issue 10. 2005-07-07. PMID:15899828. |
using hela human cervical carcinoma cells, we find that transfection of small interfering rna against the ck2 alpha and/or alpha' catalytic subunits results in enhanced apoptosis following ir damage as measured by flow cytometry techniques, compared with a control small interfering rna. |
2005-07-07 |
2023-08-12 |
human |
| Haibo Zhao, F Patrick Ross, Steven L Teitelbau. Unoccupied alpha(v)beta3 integrin regulates osteoclast apoptosis by transmitting a positive death signal. Molecular endocrinology (Baltimore, Md.). vol 19. issue 3. 2005-06-28. PMID:15591537. |
unoccupied alpha(v)beta3 integrin regulates osteoclast apoptosis by transmitting a positive death signal. |
2005-06-28 |
2023-08-12 |
Not clear |
| Haibo Zhao, F Patrick Ross, Steven L Teitelbau. Unoccupied alpha(v)beta3 integrin regulates osteoclast apoptosis by transmitting a positive death signal. Molecular endocrinology (Baltimore, Md.). vol 19. issue 3. 2005-06-28. PMID:15591537. |
consistent with the posture that alpha(v)beta3 occupancy promotes survival, preosteoclasts plated on native collagen, a matrix not recognized by the integrin, undergo apoptosis 4-fold faster than those on the alpha(v)beta3 ligand, vitronectin. |
2005-06-28 |
2023-08-12 |
Not clear |
| Haibo Zhao, F Patrick Ross, Steven L Teitelbau. Unoccupied alpha(v)beta3 integrin regulates osteoclast apoptosis by transmitting a positive death signal. Molecular endocrinology (Baltimore, Md.). vol 19. issue 3. 2005-06-28. PMID:15591537. |
to further explore the role of alpha(v)beta3 in osteoclast apoptosis, wild-type and beta3-/- preosteoclasts were suspended and apoptosis determined, with time. |
2005-06-28 |
2023-08-12 |
Not clear |