Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
R C Gallo, A Burny, D Zagur. Targeting Tat and IFN(alpha) as a therapeutic AIDS vaccine. DNA and cell biology. vol 21. issue 9. 2002-11-19. PMID:12396603. |
although there is substantial evidence for several mechanisms involved in disrupting the immune response by induction of apoptosis in responder cells by contact with infected cells, we propose that humoral factors also play a role, and that one such factor is the extracellular form of the human immunodeficiency virus (hiv)-1 tat protein and another is ifn(alpha). |
2002-11-19 |
2023-08-12 |
human |
M Richter, D Jurek, F Wrba, K Kaserer, G Wurzer, J Karner-Hanusch, B Maria. Cells obtained from colorectal microadenomas mirror early premalignant growth patterns in vitro. European journal of cancer (Oxford, England : 1990). vol 38. issue 14. 2002-11-18. PMID:12204677. |
inhibition of the egf-receptor kinase induced apoptosis at an ic(50) concentration of 4 micromolar indicating that tgf(alpha) activated survival pathways in the early adenoma cell. |
2002-11-18 |
2023-08-12 |
Not clear |
A Indrei, C L Zamfir, M Nechifo. The apoptosis of the rat and mouse testicular cells could be induced by synthetic analogous of the prostaglandin F2 alpha? Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. vol 105. issue 1. 2002-11-14. PMID:12092137. |
the apoptosis of the rat and mouse testicular cells could be induced by synthetic analogous of the prostaglandin f2 alpha? |
2002-11-14 |
2023-08-12 |
mouse |
A Indrei, C L Zamfir, M Nechifo. The apoptosis of the rat and mouse testicular cells could be induced by synthetic analogous of the prostaglandin F2 alpha? Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. vol 105. issue 1. 2002-11-14. PMID:12092137. |
this is the reason for our study, which tried to emphasize the effects of analogous of the prostaglandin f2 alpha on the apoptosis of the rat and mouse testicular cells. |
2002-11-14 |
2023-08-12 |
mouse |
Susana Castro-Alcaraz, Veronika Miskolci, Bharati Kalasapudi, Dennis Davidson, Ivana Vancurov. NF-kappa B regulation in human neutrophils by nuclear I kappa B alpha: correlation to apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 169. issue 7. 2002-11-12. PMID:12244195. |
nf-kappa b regulation in human neutrophils by nuclear i kappa b alpha: correlation to apoptosis. |
2002-11-12 |
2023-08-12 |
human |
Jacqueline Y Channon, Kristin A Miselis, Laurie A Minns, Chaitali Dutta, Lloyd H Kaspe. Toxoplasma gondii induces granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor secretion by human fibroblasts: implications for neutrophil apoptosis. Infection and immunity. vol 70. issue 11. 2002-11-08. PMID:12379681. |
delayed apoptosis correlated with up-regulation of the neutrophil antiapoptotic protein, mcl-1, and the neutrophil interleukin 3 receptor alpha subunit (il-3ralpha), suggesting a role for granulocyte-macrophage colony-stimulating factor (gm-csf). |
2002-11-08 |
2023-08-12 |
human |
Kenji Ishitsuka, Ryuji Ikeda, Atae Utsunomiya, Kimiharu Uozumi, Shuichi Hanada, Shinsuke Suzuki, Shogo Takeuchi, Yoshifusa Takatsuka, Taketsugu Takeshita, Nobuhito Ohno, Terukatsu Arim. Arsenic trioxide induces apoptosis in HTLV-I infected T-cell lines and fresh adult T-cell leukemia cells through CD95 or tumor necrosis factor alpha receptor independent caspase activation. Leukemia & lymphoma. vol 43. issue 5. 2002-11-07. PMID:12148893. |
arsenic trioxide induces apoptosis in htlv-i infected t-cell lines and fresh adult t-cell leukemia cells through cd95 or tumor necrosis factor alpha receptor independent caspase activation. |
2002-11-07 |
2023-08-12 |
human |
Wen-Shu Wu, Zhi-Xiang Xu, Kun-Sang Chan. The promyelocytic leukemia protein represses A20-mediated transcription. The Journal of biological chemistry. vol 277. issue 35. 2002-10-17. PMID:12080044. |
we also showed that stable overexpression of a20 inhibits apoptosis and caspase activation induced by pml/tnf alpha. |
2002-10-17 |
2023-08-12 |
Not clear |
Wen-Shu Wu, Zhi-Xiang Xu, Kun-Sang Chan. The promyelocytic leukemia protein represses A20-mediated transcription. The Journal of biological chemistry. vol 277. issue 35. 2002-10-17. PMID:12080044. |
the results of this study suggest that a20 is a downstream target of pml-induced apoptosis and supports a role of a20 in modulating cell death induced by pml/tnf alpha in tnf-resistant cells. |
2002-10-17 |
2023-08-12 |
Not clear |
Kelly Davison, Koren K Mann, Wilson H Mille. Arsenic trioxide: mechanisms of action. Seminars in hematology. vol 39. issue 2 Suppl 1. 2002-10-04. PMID:12012315. |
however, degradation of pml-rar alpha may not be wholly responsible for the great sensitivity of apl cells to ato, which also acts through the intracellular environment to influence apoptosis, differentiation, growth arrest, and angiogenesis. |
2002-10-04 |
2023-08-12 |
Not clear |
L Ohman, L Franzén, U Rudolph, L Birnbaumer, E Hultgren Hörnquis. Regression of Peyer's patches in G alpha i2 deficient mice prior to colitis is associated with reduced expression of Bcl-2 and increased apoptosis. Gut. vol 51. issue 3. 2002-10-02. PMID:12171962. |
regression of peyer's patches in g alpha i2 deficient mice prior to colitis is associated with reduced expression of bcl-2 and increased apoptosis. |
2002-10-02 |
2023-08-12 |
mouse |
George G Chen, Paul B S Lai, Xu Hu, Isa K Y Lam, Ernest C W Chak, Ying S Chun, Wan Y La. Negative correlation between the ratio of Bax to Bcl-2 and the size of tumor treated by culture supernatants from Kupffer cells. Clinical & experimental metastasis. vol 19. issue 5. 2002-09-13. PMID:12198774. |
the expression of tnf alpha and the occurrence of apoptosis were also increased in tumor treated with culture supernatants from activated kupffer cells, compared with those which received no treatment. |
2002-09-13 |
2023-08-12 |
mouse |
Patricia A Burke, Sally J DeNardo, Laird A Miers, Kathleen R Lamborn, Siegfried Matzku, Gerald L DeNard. Cilengitide targeting of alpha(v)beta(3) integrin receptor synergizes with radioimmunotherapy to increase efficacy and apoptosis in breast cancer xenografts. Cancer research. vol 62. issue 15. 2002-09-11. PMID:12154028. |
cilengitide targeting of alpha(v)beta(3) integrin receptor synergizes with radioimmunotherapy to increase efficacy and apoptosis in breast cancer xenografts. |
2002-09-11 |
2023-08-12 |
mouse |
Ernesto Alfaro-Moreno, Leticia Martínez, Claudia García-Cuellar, James C Bonner, J Clifford Murray, Irma Rosas, Sergio Ponce de León Rosales, Alvaro R Osornio-Varga. Biologic effects induced in vitro by PM10 from three different zones of Mexico City. Environmental health perspectives. vol 110. issue 7. 2002-09-10. PMID:12117649. |
we assessed cytotoxicity (crystal violet assay), apoptosis [terminal deoxynucleotidyl transferase-mediated dutp nick-end labeling (tunel) or annexin v assay], dna breakage (comet assay), and production of proinflammatory mediators [tumor necrosis factor alpha (tnf-alpha), interleukin 6 (il-6), prostaglandin e2 (pge2)] (enzyme-linked immunosorbent assay), and e-selectin (flow cytometry) in cell lines exposed to particulate matter < 10 microm in size (pm10) obtained from the northern, central, and southern zones of mexico city. |
2002-09-10 |
2023-08-12 |
mouse |
Jiayou Liu, Fayi Yao, Ruping Wu, Michael Morgan, Andrew Thorburn, Russell L Finley, Yong Q Che. Mediation of the DCC apoptotic signal by DIP13 alpha. The Journal of biological chemistry. vol 277. issue 29. 2002-09-06. PMID:12011067. |
although ectopic expression of dip13 alpha alone causes only a slight increase in apoptosis, co-expression of dcc and dip13 alpha results in an approximately 5-fold increase in apoptosis. |
2002-09-06 |
2023-08-12 |
Not clear |
Jiayou Liu, Fayi Yao, Ruping Wu, Michael Morgan, Andrew Thorburn, Russell L Finley, Yong Q Che. Mediation of the DCC apoptotic signal by DIP13 alpha. The Journal of biological chemistry. vol 277. issue 29. 2002-09-06. PMID:12011067. |
removal of the dcc-interacting domain on dip13 alpha abolishes its ability to enhance dcc-induced apoptosis. |
2002-09-06 |
2023-08-12 |
Not clear |
Jiayou Liu, Fayi Yao, Ruping Wu, Michael Morgan, Andrew Thorburn, Russell L Finley, Yong Q Che. Mediation of the DCC apoptotic signal by DIP13 alpha. The Journal of biological chemistry. vol 277. issue 29. 2002-09-06. PMID:12011067. |
inhibition of endogenous dip13 alpha expression by small interfering rna blocks dcc-induced apoptosis. |
2002-09-06 |
2023-08-12 |
Not clear |
A Mattana, V Cappai, L Alberti, C Serra, P L Fiori, P Cappuccinell. ADP and other metabolites released from Acanthamoeba castellanii lead to human monocytic cell death through apoptosis and stimulate the secretion of proinflammatory cytokines. Infection and immunity. vol 70. issue 8. 2002-09-04. PMID:12117953. |
we demonstrate here that adp constitutively released in the medium by a. castellanii, interacting with specific p2y(2) purinoceptors expressed on the monocytic cell membrane, caused a biphasic rise in [ca(2+)](i), morphological changes characteristics of cells undergoing apoptosis, caspase-3 activation, and secretion of tumor necrosis factor alpha (tnf-alpha). |
2002-09-04 |
2023-08-12 |
human |
V L Hedge, G T William. Commitment to apoptosis induced by tumour necrosis factor-alpha is dependent on caspase activity. Apoptosis : an international journal on programmed cell death. vol 7. issue 2. 2002-08-30. PMID:11865196. |
tumour necrosis factor alpha binding at the cell surface induces a complex series of signaling events culminating in the caspase cascade, which is central to apoptosis. |
2002-08-30 |
2023-08-12 |
human |
Chang-Kyu Lee, Jorge A Piedrahit. Inhibition of apoptosis in serum starved porcine embryonic fibroblasts. Molecular reproduction and development. vol 62. issue 1. 2002-08-27. PMID:11933167. |
this study was performed to characterize apoptosis during serum starvation and to determine the effects of apoptosis inhibitors such as a protease inhibitor [alpha(2)-macroglobulin (mac)] and antioxidants [n-acetylcysteine (nac), glutathione (gsh)] on serum starved porcine embryonic fibroblasts (pef). |
2002-08-27 |
2023-08-12 |
Not clear |