| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hella Wobser, Heiko Düssmann, Donat Kögel, Haiyan Wang, Claus Reimertz, Claes B Wollheim, Maria M Byrne, Jochen H M Preh. Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death. The Journal of biological chemistry. vol 277. issue 8. 2002-04-24. PMID:11724785. |
dominant-negative suppression of hnf-1 alpha results in mitochondrial dysfunction, ins-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death. |
2002-04-24 |
2023-08-12 |
human |
| Petra Pfisterer, Julia Ehlermann, Martin Hegen, Hubert Schorl. A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation. The Journal of biological chemistry. vol 277. issue 8. 2002-04-24. PMID:11741941. |
by using a subtractive cloning approach, we identified a set of genes repressed by ap-2 alpha that are described to retard cellular proliferation and induce differentiation and apoptosis. |
2002-04-24 |
2023-08-12 |
mouse |
| Petra Pfisterer, Julia Ehlermann, Martin Hegen, Hubert Schorl. A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation. The Journal of biological chemistry. vol 277. issue 8. 2002-04-24. PMID:11741941. |
we show that fibroblasts lacking ap-2 alpha display retarded growth but no enhanced apoptosis. |
2002-04-24 |
2023-08-12 |
mouse |
| Petra Pfisterer, Julia Ehlermann, Martin Hegen, Hubert Schorl. A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation. The Journal of biological chemistry. vol 277. issue 8. 2002-04-24. PMID:11741941. |
based on these data we suggest that ap-2 alpha might be required for cell proliferation by suppression of genes inducing terminal differentiation, apoptosis, and growth retardation. |
2002-04-24 |
2023-08-12 |
mouse |
| Leisa J Morrison, Jennifer L Marcinkiewic. Tumor necrosis factor alpha enhances oocyte/follicle apoptosis in the neonatal rat ovary. Biology of reproduction. vol 66. issue 2. 2002-04-23. PMID:11804962. |
tumor necrosis factor alpha enhances oocyte/follicle apoptosis in the neonatal rat ovary. |
2002-04-23 |
2023-08-12 |
rat |
| Christopher J Dougherty, Lori A Kubasiak, Howard Prentice, Peter Andreka, Nanette H Bishopric, Keith A Webste. Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress. The Biochemical journal. vol 362. issue Pt 3. 2002-04-19. PMID:11879182. |
hypoxia-reoxygenation mediated a biphasic (2.6- and 2.9-fold) activation of p38 mitogen-activated protein kinase, as well as a small increase of tumour necrosis factor alpha (tnfalpha) secretion, but treatments with the p38 mapk-specific inhibitor sb203580 or saturating levels of a tnfalpha-1 blocking antibody provided only partial protection against apoptosis. |
2002-04-19 |
2023-08-12 |
Not clear |
| T J MacDonald, S Ladisc. Antisense to integrin alpha v inhibits growth and induces apoptosis in medulloblastoma cells. Anticancer research. vol 21. issue 6A. 2002-04-19. PMID:11911248. |
antisense to integrin alpha v inhibits growth and induces apoptosis in medulloblastoma cells. |
2002-04-19 |
2023-08-12 |
Not clear |
| Takashi Taga, Atsushi Suzuki, Ignacio Gonzalez-Gomez, Floyd H Gilles, Monique Stins, Hiroyuki Shimada, Lora Barsky, Kenneth I Weinberg, Walter E Lau. alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. International journal of cancer. vol 98. issue 5. 2002-04-18. PMID:11920637. |
alpha v-integrin antagonist emd 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. |
2002-04-18 |
2023-08-12 |
mouse |
| Takashi Taga, Atsushi Suzuki, Ignacio Gonzalez-Gomez, Floyd H Gilles, Monique Stins, Hiroyuki Shimada, Lora Barsky, Kenneth I Weinberg, Walter E Lau. alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. International journal of cancer. vol 98. issue 5. 2002-04-18. PMID:11920637. |
this compound, a cyclic rgd-penta-peptide, is a potent inhibitor of angiogenesis, which induces apoptosis of growing endothelial cells through inhibition of their alpha v-integrin interaction with the matrix proteins vitronectin and tenascin. |
2002-04-18 |
2023-08-12 |
mouse |
| Takashi Taga, Atsushi Suzuki, Ignacio Gonzalez-Gomez, Floyd H Gilles, Monique Stins, Hiroyuki Shimada, Lora Barsky, Kenneth I Weinberg, Walter E Lau. alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. International journal of cancer. vol 98. issue 5. 2002-04-18. PMID:11920637. |
here we show that emd 121974 also induces apoptosis in the alpha v-integrin-expressing tumor cell lines u87 mg and daoy by detaching them from vitronectin and tenascin, matrix proteins known to be essential for brain tumor growth and invasion. |
2002-04-18 |
2023-08-12 |
mouse |
| Takashi Taga, Atsushi Suzuki, Ignacio Gonzalez-Gomez, Floyd H Gilles, Monique Stins, Hiroyuki Shimada, Lora Barsky, Kenneth I Weinberg, Walter E Lau. alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. International journal of cancer. vol 98. issue 5. 2002-04-18. PMID:11920637. |
thus, the alpha v-antagonist emd 121974 suppresses brain tumor growth through induction of apoptosis in both brain capillary and brain tumor cells by preventing their interaction with the matrix proteins vitronectin and tenascin. |
2002-04-18 |
2023-08-12 |
mouse |
| Hailing Liu, Chau R Lo, Mark J Czaj. NF-kappaB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun. Hepatology (Baltimore, Md.). vol 35. issue 4. 2002-04-17. PMID:11915022. |
hepatocyte resistance to tumor necrosis factor alpha (tnf)-induced apoptosis is dependent on activation of the transcription factor nuclear factor kappab (nf-kappab). |
2002-04-17 |
2023-08-12 |
rat |
| Motohiro Nishida, Shuichi Takagahara, Yoshiko Maruyama, Yoshiyuki Sugimoto, Taku Nagao, Hitoshi Kuros. G beta gamma counteracts G alpha(q) signaling upon alpha(1)-adrenergic receptor stimulation. Biochemical and biophysical research communications. vol 291. issue 4. 2002-04-15. PMID:11866464. |
in rat neonatal myocytes, a constitutively active g alpha(q) causes cellular injury and apoptosis. |
2002-04-15 |
2023-08-12 |
rat |
| Motohiro Nishida, Shuichi Takagahara, Yoshiko Maruyama, Yoshiyuki Sugimoto, Taku Nagao, Hitoshi Kuros. G beta gamma counteracts G alpha(q) signaling upon alpha(1)-adrenergic receptor stimulation. Biochemical and biophysical research communications. vol 291. issue 4. 2002-04-15. PMID:11866464. |
however, stimulation of the alpha(1)-adrenergic receptor, one of the g(q) protein-coupled receptors, with phenylephrine for 48 h causes little cellular injury and apoptosis. |
2002-04-15 |
2023-08-12 |
rat |
| Motohiro Nishida, Shuichi Takagahara, Yoshiko Maruyama, Yoshiyuki Sugimoto, Taku Nagao, Hitoshi Kuros. G beta gamma counteracts G alpha(q) signaling upon alpha(1)-adrenergic receptor stimulation. Biochemical and biophysical research communications. vol 291. issue 4. 2002-04-15. PMID:11866464. |
however, activation of akt but not erk plays an important role in the protection against the g alpha(q)-induced cellular injury and apoptosis. |
2002-04-15 |
2023-08-12 |
rat |
| Shuang Wei, Florentina Marches, Jozef Borvak, Weiping Zou, Jacqueline Channon, Michael White, Jay Radke, Marie-France Cesbron-Delauw, Tyler J Curie. Toxoplasma gondii-infected human myeloid dendritic cells induce T-lymphocyte dysfunction and contact-dependent apoptosis. Infection and immunity. vol 70. issue 4. 2002-04-11. PMID:11895936. |
t lymphocytes exposed to infected mddcs are significantly impaired in upregulation of cd69 and cd28, are refractory to activation, and die through contact-dependent apoptosis mediated by an as-yet-unidentified mechanism not requiring fas, tumor necrosis factor-related apoptosis-inducing ligand, leukocyte function antigen 1, intercellular adhesion molecule 1, tumor necrosis factor alpha, interleukin 10, alpha interferon, gamma interferon, prostaglandins, or reactive nitrogen intermediates. |
2002-04-11 |
2023-08-12 |
human |
| Susan R Rittling, Yanping Chen, Fei Feng, Yiming W. Tumor-derived osteopontin is soluble, not matrix associated. The Journal of biological chemistry. vol 277. issue 11. 2002-04-05. PMID:11741994. |
the secreted phosphoprotein osteopontin (opn), when immobilized on a surface, supports cell adhesion, prevents apoptosis of endothelial cells, and is a ligand for the alpha(v)beta(3) integrin, which is important in endothelial cell biology and neovascularization. |
2002-04-05 |
2023-08-12 |
mouse |
| C M Telleria, A A Goyeneche, J C Cavicchia, A O Stati, R P Dei. Apoptosis induced by antigestagen RU486 in rat corpus luteum of pregnancy. Endocrine. vol 15. issue 2. 2002-04-04. PMID:11720240. |
prostaglandin f2,alpha(pgf2alpha), which mediates the luteolytic action of ru486, mimicked the effect of the antigestagen on the induction of apoptosis when administered to rats on d 18 of pregnancy (100 microg at 9:00 am and 1:00 pm), which were killed 72 after the last injection. |
2002-04-04 |
2023-08-12 |
rat |
| Makoto Kamachi, Atsushi Kawakami, Satoshi Yamasaki, Ayumi Hida, Tomoki Nakashima, Hideki Nakamura, Hiroaki Ida, Masako Furuyama, Koto Nakashima, Kazutaka Shibatomi, Taiichiro Miyashita, Kiyoshi Migita, Katsumi Eguch. Regulation of apoptotic cell death by cytokines in a human salivary gland cell line: distinct and synergistic mechanisms in apoptosis induced by tumor necrosis factor alpha and interferon gamma. The Journal of laboratory and clinical medicine. vol 139. issue 1. 2002-04-02. PMID:11873240. |
regulation of apoptotic cell death by cytokines in a human salivary gland cell line: distinct and synergistic mechanisms in apoptosis induced by tumor necrosis factor alpha and interferon gamma. |
2002-04-02 |
2023-08-12 |
human |
| Makoto Kamachi, Atsushi Kawakami, Satoshi Yamasaki, Ayumi Hida, Tomoki Nakashima, Hideki Nakamura, Hiroaki Ida, Masako Furuyama, Koto Nakashima, Kazutaka Shibatomi, Taiichiro Miyashita, Kiyoshi Migita, Katsumi Eguch. Regulation of apoptotic cell death by cytokines in a human salivary gland cell line: distinct and synergistic mechanisms in apoptosis induced by tumor necrosis factor alpha and interferon gamma. The Journal of laboratory and clinical medicine. vol 139. issue 1. 2002-04-02. PMID:11873240. |
we examined the mechanisms of apoptosis in a human salivary gland (hsg) cell line induced by tumor necrosis factor (tnf) alpha and interferon (ifn) gamma. |
2002-04-02 |
2023-08-12 |
human |