| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesca Fallarino, Carmine Vacca, Ciriana Orabona, Maria L Belladonna, Roberta Bianchi, Brendan Marshall, Derin B Keskin, Andrew L Mellor, Maria C Fioretti, Ursula Grohmann, Paolo Puccett. Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. International immunology. vol 14. issue 1. 2002-05-23. PMID:11751753. |
following activation by ifn-gamma, the latter cells, in particular the cd8 alpha(+) subset, exhibit high functional activity and, unlike macrophages, mediate apoptosis of t(h) cells in vitro. |
2002-05-23 |
2023-08-12 |
mouse |
| Patrick Diel, Sabine Olff, Simone Schmidt, Horst Michn. Effects of the environmental estrogens bisphenol A, o,p'-DDT, p-tert-octylphenol and coumestrol on apoptosis induction, cell proliferation and the expression of estrogen sensitive molecular parameters in the human breast cancer cell line MCF-7. The Journal of steroid biochemistry and molecular biology. vol 80. issue 1. 2002-05-14. PMID:11867264. |
in the presented study, we have analysed effects of the environmental estrogens bisphenol a (bpa), p-tert-octylphenol (oct), o,p'-ddt (ddt) and coumestrol (cou) on cell proliferation, apoptosis induction, progesterone receptor (pr) and androgen receptor (ar) mrna expression and er alpha protein expression in comparison to estradiol (e2) and the selective er modulator (serm) raloxifene (ral) and the pure antiestrogen faslodex (ici 182780) in the human breast cancer cell line mcf-7. |
2002-05-14 |
2023-08-12 |
human |
| M F Lucero Gritti, M Beviacqua, R H Bordenave, L S Rum. Interferon-alpha 2b modulation of doxorubicin sensitivity in a multidrug resistant cell line. Journal of experimental & clinical cancer research : CR. vol 20. issue 3. 2002-05-02. PMID:11718220. |
dox 50 ng/ml - ifn alpha 2b 500 iu/ml treatment inhibited cell proliferation (47.2 +/- 1.4%, p < 0.0001; mtt assay: 40.6 +/- 1.2%, p < 0.0001) and augmented the expression of p-170, bcl-2 and hla-abc, while it didn't exert apoptosis, producing a slight g2/m arrest. |
2002-05-02 |
2023-08-12 |
Not clear |
| Usha P Andley, Harendra C Patel, Jing-Hua X. The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis. The Journal of biological chemistry. vol 277. issue 12. 2002-04-29. PMID:11756414. |
the r116c mutation in alpha a-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis. |
2002-04-29 |
2023-08-12 |
human |
| Rodolphe Filomenko, Florence Poirson-Bichat, Claire Billerey, Jean-Paul Belon, Carmen Garrido, Eric Solary, Ali Bettaie. Atypical protein kinase C zeta as a target for chemosensitization of tumor cells. Cancer research. vol 62. issue 6. 2002-04-29. PMID:11912160. |
pkczeta inhibition accelerates the occurrence of apoptosis in leukemic cells exposed to etoposide and tumor necrosis factor alpha. |
2002-04-29 |
2023-08-12 |
mouse |
| Hella Wobser, Heiko Düssmann, Donat Kögel, Haiyan Wang, Claus Reimertz, Claes B Wollheim, Maria M Byrne, Jochen H M Preh. Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death. The Journal of biological chemistry. vol 277. issue 8. 2002-04-24. PMID:11724785. |
dominant-negative suppression of hnf-1 alpha results in mitochondrial dysfunction, ins-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death. |
2002-04-24 |
2023-08-12 |
human |
| Petra Pfisterer, Julia Ehlermann, Martin Hegen, Hubert Schorl. A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation. The Journal of biological chemistry. vol 277. issue 8. 2002-04-24. PMID:11741941. |
by using a subtractive cloning approach, we identified a set of genes repressed by ap-2 alpha that are described to retard cellular proliferation and induce differentiation and apoptosis. |
2002-04-24 |
2023-08-12 |
mouse |
| Petra Pfisterer, Julia Ehlermann, Martin Hegen, Hubert Schorl. A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation. The Journal of biological chemistry. vol 277. issue 8. 2002-04-24. PMID:11741941. |
we show that fibroblasts lacking ap-2 alpha display retarded growth but no enhanced apoptosis. |
2002-04-24 |
2023-08-12 |
mouse |
| Petra Pfisterer, Julia Ehlermann, Martin Hegen, Hubert Schorl. A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation. The Journal of biological chemistry. vol 277. issue 8. 2002-04-24. PMID:11741941. |
based on these data we suggest that ap-2 alpha might be required for cell proliferation by suppression of genes inducing terminal differentiation, apoptosis, and growth retardation. |
2002-04-24 |
2023-08-12 |
mouse |
| Leisa J Morrison, Jennifer L Marcinkiewic. Tumor necrosis factor alpha enhances oocyte/follicle apoptosis in the neonatal rat ovary. Biology of reproduction. vol 66. issue 2. 2002-04-23. PMID:11804962. |
tumor necrosis factor alpha enhances oocyte/follicle apoptosis in the neonatal rat ovary. |
2002-04-23 |
2023-08-12 |
rat |
| Christopher J Dougherty, Lori A Kubasiak, Howard Prentice, Peter Andreka, Nanette H Bishopric, Keith A Webste. Activation of c-Jun N-terminal kinase promotes survival of cardiac myocytes after oxidative stress. The Biochemical journal. vol 362. issue Pt 3. 2002-04-19. PMID:11879182. |
hypoxia-reoxygenation mediated a biphasic (2.6- and 2.9-fold) activation of p38 mitogen-activated protein kinase, as well as a small increase of tumour necrosis factor alpha (tnfalpha) secretion, but treatments with the p38 mapk-specific inhibitor sb203580 or saturating levels of a tnfalpha-1 blocking antibody provided only partial protection against apoptosis. |
2002-04-19 |
2023-08-12 |
Not clear |
| T J MacDonald, S Ladisc. Antisense to integrin alpha v inhibits growth and induces apoptosis in medulloblastoma cells. Anticancer research. vol 21. issue 6A. 2002-04-19. PMID:11911248. |
antisense to integrin alpha v inhibits growth and induces apoptosis in medulloblastoma cells. |
2002-04-19 |
2023-08-12 |
Not clear |
| Takashi Taga, Atsushi Suzuki, Ignacio Gonzalez-Gomez, Floyd H Gilles, Monique Stins, Hiroyuki Shimada, Lora Barsky, Kenneth I Weinberg, Walter E Lau. alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. International journal of cancer. vol 98. issue 5. 2002-04-18. PMID:11920637. |
alpha v-integrin antagonist emd 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. |
2002-04-18 |
2023-08-12 |
mouse |
| Takashi Taga, Atsushi Suzuki, Ignacio Gonzalez-Gomez, Floyd H Gilles, Monique Stins, Hiroyuki Shimada, Lora Barsky, Kenneth I Weinberg, Walter E Lau. alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. International journal of cancer. vol 98. issue 5. 2002-04-18. PMID:11920637. |
this compound, a cyclic rgd-penta-peptide, is a potent inhibitor of angiogenesis, which induces apoptosis of growing endothelial cells through inhibition of their alpha v-integrin interaction with the matrix proteins vitronectin and tenascin. |
2002-04-18 |
2023-08-12 |
mouse |
| Takashi Taga, Atsushi Suzuki, Ignacio Gonzalez-Gomez, Floyd H Gilles, Monique Stins, Hiroyuki Shimada, Lora Barsky, Kenneth I Weinberg, Walter E Lau. alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. International journal of cancer. vol 98. issue 5. 2002-04-18. PMID:11920637. |
here we show that emd 121974 also induces apoptosis in the alpha v-integrin-expressing tumor cell lines u87 mg and daoy by detaching them from vitronectin and tenascin, matrix proteins known to be essential for brain tumor growth and invasion. |
2002-04-18 |
2023-08-12 |
mouse |
| Takashi Taga, Atsushi Suzuki, Ignacio Gonzalez-Gomez, Floyd H Gilles, Monique Stins, Hiroyuki Shimada, Lora Barsky, Kenneth I Weinberg, Walter E Lau. alpha v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin. International journal of cancer. vol 98. issue 5. 2002-04-18. PMID:11920637. |
thus, the alpha v-antagonist emd 121974 suppresses brain tumor growth through induction of apoptosis in both brain capillary and brain tumor cells by preventing their interaction with the matrix proteins vitronectin and tenascin. |
2002-04-18 |
2023-08-12 |
mouse |
| Hailing Liu, Chau R Lo, Mark J Czaj. NF-kappaB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun. Hepatology (Baltimore, Md.). vol 35. issue 4. 2002-04-17. PMID:11915022. |
hepatocyte resistance to tumor necrosis factor alpha (tnf)-induced apoptosis is dependent on activation of the transcription factor nuclear factor kappab (nf-kappab). |
2002-04-17 |
2023-08-12 |
rat |
| Motohiro Nishida, Shuichi Takagahara, Yoshiko Maruyama, Yoshiyuki Sugimoto, Taku Nagao, Hitoshi Kuros. G beta gamma counteracts G alpha(q) signaling upon alpha(1)-adrenergic receptor stimulation. Biochemical and biophysical research communications. vol 291. issue 4. 2002-04-15. PMID:11866464. |
in rat neonatal myocytes, a constitutively active g alpha(q) causes cellular injury and apoptosis. |
2002-04-15 |
2023-08-12 |
rat |
| Motohiro Nishida, Shuichi Takagahara, Yoshiko Maruyama, Yoshiyuki Sugimoto, Taku Nagao, Hitoshi Kuros. G beta gamma counteracts G alpha(q) signaling upon alpha(1)-adrenergic receptor stimulation. Biochemical and biophysical research communications. vol 291. issue 4. 2002-04-15. PMID:11866464. |
however, stimulation of the alpha(1)-adrenergic receptor, one of the g(q) protein-coupled receptors, with phenylephrine for 48 h causes little cellular injury and apoptosis. |
2002-04-15 |
2023-08-12 |
rat |
| Motohiro Nishida, Shuichi Takagahara, Yoshiko Maruyama, Yoshiyuki Sugimoto, Taku Nagao, Hitoshi Kuros. G beta gamma counteracts G alpha(q) signaling upon alpha(1)-adrenergic receptor stimulation. Biochemical and biophysical research communications. vol 291. issue 4. 2002-04-15. PMID:11866464. |
however, activation of akt but not erk plays an important role in the protection against the g alpha(q)-induced cellular injury and apoptosis. |
2002-04-15 |
2023-08-12 |
rat |