| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Waleed Khalaf, Caroline Maina, Joseph Byers, William Harve. Interferon-alpha 2b and vesnarinone influence levels of tumor necrosis factor-alpha, apoptosis, or interleukin 6 in ESKOL, a hairy cell leukemic cell line. A potential cytokine and oncogene relationship regulating apoptosis is suggested. Leukemia research. vol 26. issue 2. 2002-03-27. PMID:11755467. |
ifn enhances differentiation in eskol, decreases tnf alpha levels, decreases apoptosis, increases il-6 levels, and down regulates the expression of several oncogenes. |
2002-03-27 |
2023-08-12 |
Not clear |
| Waleed Khalaf, Caroline Maina, Joseph Byers, William Harve. Interferon-alpha 2b and vesnarinone influence levels of tumor necrosis factor-alpha, apoptosis, or interleukin 6 in ESKOL, a hairy cell leukemic cell line. A potential cytokine and oncogene relationship regulating apoptosis is suggested. Leukemia research. vol 26. issue 2. 2002-03-27. PMID:11755467. |
vesnarinone (ves), a tnf alpha repressor, lowers tnf-alpha and decreases apoptosis in the same cell line. |
2002-03-27 |
2023-08-12 |
Not clear |
| Waleed Khalaf, Caroline Maina, Joseph Byers, William Harve. Interferon-alpha 2b and vesnarinone influence levels of tumor necrosis factor-alpha, apoptosis, or interleukin 6 in ESKOL, a hairy cell leukemic cell line. A potential cytokine and oncogene relationship regulating apoptosis is suggested. Leukemia research. vol 26. issue 2. 2002-03-27. PMID:11755467. |
we suggest that ifn decreases apoptosis by mechanisms involving enhanced il-6 and bcl-2 levels, decreased tnf alpha and the down regulation of apoptotic oncogenes, including c-myc. |
2002-03-27 |
2023-08-12 |
Not clear |
| C Guiet, E Silvestri, E De Smaele, G Franzoso, P Vit. c-FLIP efficiently rescues TRAF-2-/- cells from TNF-induced apoptosis. Cell death and differentiation. vol 9. issue 2. 2002-03-27. PMID:11840164. |
for the past 20 years, it has been known that preparations of tumor necrosis factor alpha (tnf) fail to induce apoptosis due to cytoprotective responses that render cells resistant to its cytotoxic activity. |
2002-03-27 |
2023-08-12 |
Not clear |
| W F Westli. Integrins as targets of angiogenesis inhibition. Cancer journal (Sudbury, Mass.). vol 7 Suppl 3. 2002-03-20. PMID:11779085. |
inhibition of alpha(v)beta3 can modulate tumor-induced angiogenesis and can increase apoptosis of tumor-associated small blood vessels. |
2002-03-20 |
2023-08-12 |
Not clear |
| J Li, R Zheng, J Li, Z Wan. Mechanisms of the induction of apoptosis in human hepatoma cells by tumour necrosis factor-alpha. Cell biology international. vol 25. issue 12. 2002-03-19. PMID:11748914. |
tumour necrosis factor alpha (tnf-alpha) at 20 ng/ml induced apoptosis in human hepatoma cells in vitro. |
2002-03-19 |
2023-08-12 |
human |
| Karine L Régnauld, Emmanuelle Leteurtre, Silvio J Gutkind, Christian P Gespach, Shahin Emam. Activation of adenylyl cyclases, regulation of insulin status, and cell survival by G(alpha)olf in pancreatic beta-cells. American journal of physiology. Regulatory, integrative and comparative physiology. vol 282. issue 3. 2002-03-15. PMID:11832410. |
furthermore, betatc-3-ag(alpha)olf cells are resistant to serum starvation-induced apoptosis. |
2002-03-15 |
2023-08-12 |
mouse |
| A V Sirotkin, A V Makarevic. Growth hormone can regulate functions of porcine ovarian granulosa cells through the cAMP/protein kinase A system. Animal reproduction science. vol 70. issue 1-2. 2002-03-15. PMID:11841911. |
for this purpose, the effects of exogenous pgh (1-10,000 ng/ml), pka blockers kt5720 (100 ng/ml) and rp-camps (1micromol), alone and in combination, on insulin-like growth factor type i (igf-i), insulin-like binding protein 3 (igfbp-3), oxytocin (ot) and prostaglandin f alpha (pgf) secretion, pka and camp response element binding transcription factor (creb) content and the occurrence of apoptosis were investigated. |
2002-03-15 |
2023-08-12 |
Not clear |
| M Rees, M Stahl, B Klump, R Willers, H E Gabbert, M Sarbi. The prognostic significance of proliferative activity, apoptosis and expression of DNA topoisomerase II alpha in multimodally-treated oesophageal squamous cell carcinoma. Anticancer research. vol 21. issue 5. 2002-03-12. PMID:11848536. |
the prognostic significance of proliferative activity, apoptosis and expression of dna topoisomerase ii alpha in multimodally-treated oesophageal squamous cell carcinoma. |
2002-03-12 |
2023-08-12 |
Not clear |
| Y Chen, J Miao, X Zh. [Design and synthesis of anti-PML-RAR alpha antisense and its effects on the growth and apoptosis of NB4 cells]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. vol 20. issue 6. 2002-03-08. PMID:11721388. |
[design and synthesis of anti-pml-rar alpha antisense and its effects on the growth and apoptosis of nb4 cells]. |
2002-03-08 |
2023-08-12 |
Not clear |
| Y Chen, J Miao, X Zh. [Design and synthesis of anti-PML-RAR alpha antisense and its effects on the growth and apoptosis of NB4 cells]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. vol 20. issue 6. 2002-03-08. PMID:11721388. |
to synthesize antisense oligodeoxynucleotides (as) targeting the fusion point region (fuas) and the start codon region (stas) of the long type pml-rar alpha mrna and investigate its stability, specificity and effects on the growth and apoptosis of nb4 cells. |
2002-03-08 |
2023-08-12 |
Not clear |
| Delphine Javelaud, Marie-France Poupon, Juana Wietzerbin, Françoise Besanço. Inhibition of constitutive NF-kappa B activity suppresses tumorigenicity of Ewing sarcoma EW7 cells. International journal of cancer. vol 98. issue 2. 2002-03-07. PMID:11857407. |
it causes, however, a remarkable loss of their ability to generate tumors in nude mice that correlates with both a decrease in extracellular matrix (ecm) protein secretion and an acquisition of sensitivity to murine tumor necrosis factor alpha (tnf alpha)-induced apoptosis. |
2002-03-07 |
2023-08-12 |
mouse |
| F Zorat, V Shetty, D Dutt, L Lisak, F Nascimben, K Allampallam, S Dar, A York, S Gezer, P Venugopal, A Raz. The clinical and biological effects of thalidomide in patients with myelodysplastic syndromes. British journal of haematology. vol 115. issue 4. 2002-03-06. PMID:11843822. |
levels of apoptosis, macrophage number, microvessel density (mvd), tumour necrosis factor alpha (tnf-alpha), transforming growth factor beta (tgf-beta), interleukin 6 (il-6), vascular endothelial growth factor (vegf) and basic fibroblast growth factor (bfgf) were determined in the serum, bone marrow (bm) plasma and bm biopsies before and after therapy. |
2002-03-06 |
2023-08-12 |
human |
| Steven W Kubalak, D Reneé Hutson, Karen K Scott, Rebecca A Shanno. Elevated transforming growth factor beta2 enhances apoptosis and contributes to abnormal outflow tract and aortic sac development in retinoic X receptor alpha knockout embryos. Development (Cambridge, England). vol 129. issue 3. 2002-03-04. PMID:11830573. |
elevated transforming growth factor beta2 enhances apoptosis and contributes to abnormal outflow tract and aortic sac development in retinoic x receptor alpha knockout embryos. |
2002-03-04 |
2023-08-12 |
mouse |
| J A Morales González, J Gutiérrez Salinas, J Paz Avila, L F Sauceda González, J L Montes Baldera. [Transforming growth factor alpha (TGF-alpha) and epidermoid growth factor (EGF) in polycystic ovary syndrome: potential role in the decrease of apoptosis mechanisms in the follicle]. Ginecologia y obstetricia de Mexico. vol 69. 2002-03-01. PMID:11552458. |
[transforming growth factor alpha (tgf-alpha) and epidermoid growth factor (egf) in polycystic ovary syndrome: potential role in the decrease of apoptosis mechanisms in the follicle]. |
2002-03-01 |
2023-08-12 |
Not clear |
| L Zhong, J You, Q Su. [The role of NF-kappa B in the TNF-alpha-induced endothelial cell apoptosis]. Zhonghua yi xue za zhi. vol 79. issue 11. 2002-02-26. PMID:11715495. |
to investigate whether tnf-alpha could activate the signaling pathway-nf-kappa b/i-kappa b alpha required for the expression of inducible nitric oxide synthase (inos) to induce endothelial cell apoptosis by nitric oxide (no). |
2002-02-26 |
2023-08-12 |
Not clear |
| M J Clemen. Initiation factor eIF2 alpha phosphorylation in stress responses and apoptosis. Progress in molecular and subcellular biology. vol 27. 2002-02-25. PMID:11575161. |
initiation factor eif2 alpha phosphorylation in stress responses and apoptosis. |
2002-02-25 |
2023-08-12 |
Not clear |
| M J Clemen. Initiation factor eIF2 alpha phosphorylation in stress responses and apoptosis. Progress in molecular and subcellular biology. vol 27. 2002-02-25. PMID:11575161. |
physiological conditions which result in eif2 alpha phosphorylation include virus infection, heat shock, iron deficiency, nutrient deprivation, changes in intracellular calcium, accumulation of unfolded or denatured proteins and the induction of apoptosis. |
2002-02-25 |
2023-08-12 |
Not clear |
| Hans Carl Hasselbalch, Birgitte Ravn Juhl, Per Boye Hanse. [The myelodysplastic syndrome I. Pathogenesis, clinical symptoms, diagnosis and differential diagnosis]. Ugeskrift for laeger. vol 164. issue 4. 2002-02-21. PMID:11838417. |
an increased intramedullary production of various cytokines that inhibit haematopoiesis, including tumour necrosis factor alpha (tnf-alpha), may be responsible for the accelerated cell death (apoptosis). |
2002-02-21 |
2023-08-12 |
Not clear |
| F Le Bellego, C Pisselet, C Huet, P Monget, D Monniau. Laminin-alpha6beta1 integrin interaction enhances survival and proliferation and modulates steroidogenesis of ovine granulosa cells. The Journal of endocrinology. vol 172. issue 1. 2002-02-15. PMID:11786373. |
in vitro, the addition of a function-blocking antibody raised against alpha(6) subunit (anti-alpha(6) igg) to the medium of ovine gc cultured on ln impaired cell spreading (p<0.0001), decreased the proliferation rate (p<0.05) and increased the apoptosis rate (p<0.05). |
2002-02-15 |
2023-08-12 |
Not clear |