| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M P Mattson, D S Gary, S L Chan, W Dua. Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease. Biochemical Society symposium. issue 67. 2001-12-14. PMID:11447832. |
in contrast, sapp alpha activates signalling pathways that protect synapses against excitotoxicity and apoptosis. |
2001-12-14 |
2023-08-12 |
mouse |
| M A Freyberg, D Kaiser, R Graf, P Fried. Vascular endothelial cells express a functional fas-receptor due to lack of hemodynamic forces. Apoptosis : an international journal on programmed cell death. vol 6. issue 5. 2001-12-10. PMID:11483857. |
recently it was reported that in endothelial cells the lack of hemodynamic forces as well as irregular flow conditions trigger apoptosis by induction of a mechanosensitive autocrine loop of thrombospondin-1 and the alpha(v)beta(3) integrin/integrin-associated protein complex. |
2001-12-10 |
2023-08-12 |
Not clear |
| N L Toomey, V V Deyev, C Wood, L H Boise, D Scott, L H Liu, L Cabral, E R Podack, G N Barber, W J Harringto. Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma. Oncogene. vol 20. issue 48. 2001-12-07. PMID:11704827. |
we have found that azidothymidine (azt) alone induces apoptosis in epstein barr virus (ebv) positive burkitt's lymphoma (bl) cells but requires interferon alpha (ifn-alpha) to induce apoptosis in human herpes virus type 8 (hhv-8) positive primary effusion lymphomas (pel). |
2001-12-07 |
2023-08-12 |
human |
| A Colell, O Coll, C García-Ruiz, R París, C Tiribelli, N Kaplowitz, J C Fernández-Chec. Tauroursodeoxycholic acid protects hepatocytes from ethanol-fed rats against tumor necrosis factor-induced cell death by replenishing mitochondrial glutathione. Hepatology (Baltimore, Md.). vol 34. issue 5. 2001-12-04. PMID:11679967. |
mitochondrial glutathione (gsh) plays a key role against tumor necrosis factor alpha (tnf)-induced apoptosis because its depletion is known to sensitize hepatocytes to tnf. |
2001-12-04 |
2023-08-12 |
rat |
| K Zachrisson, V Neopikhanov, A Samali, A Urib. Interleukin-1, interleukin-8, tumour necrosis factor alpha and interferon gamma stimulate DNA synthesis but have no effect on apoptosis in small-intestinal cell lines. European journal of gastroenterology & hepatology. vol 13. issue 5. 2001-10-25. PMID:11396536. |
interleukin-1, interleukin-8, tumour necrosis factor alpha and interferon gamma stimulate dna synthesis but have no effect on apoptosis in small-intestinal cell lines. |
2001-10-25 |
2023-08-12 |
human |
| M W Bergmann, P Loser, R Dietz, R von Harsdor. Effect of NF-kappa B Inhibition on TNF-alpha-induced apoptosis and downstream pathways in cardiomyocytes. Journal of molecular and cellular cardiology. vol 33. issue 6. 2001-10-25. PMID:11444925. |
however, specific inhibition of nf-kappa b activation by ad5-i kappa b alpha delta n (moi=50) or mg132 (5 microm) increased apoptosis as measured by subg1-assay (h9c2 cells) and annexin v binding/propidium iodide (neonatal cardiomyocytes, facs-analysis: 7+/-2% to 26+/-5% annexin v positive/pi negative), respectively. |
2001-10-25 |
2023-08-12 |
mouse |
| V Baud, M Kari. Signal transduction by tumor necrosis factor and its relatives. Trends in cell biology. vol 11. issue 9. 2001-10-25. PMID:11514191. |
tumor necrosis factor alpha (tnfalpha) is a potent proinflammatory cytokine that plays an important role in immunity and inflammation, and in the control of cell proliferation, differentiation and apoptosis. |
2001-10-25 |
2023-08-12 |
Not clear |
| E J Foulstone, K A Meadows, J M Holly, C E Stewar. Insulin-like growth factors (IGF-I and IGF-II) inhibit C2 skeletal myoblast differentiation and enhance TNF alpha-induced apoptosis. Journal of cellular physiology. vol 189. issue 2. 2001-10-25. PMID:11598906. |
addition of 20 ng/ml tnf alpha on transfer into lsm blocked differentiation, igf-ii and igfbp-5 secretion and induced apoptosis. |
2001-10-25 |
2023-08-12 |
Not clear |
| E J Foulstone, K A Meadows, J M Holly, C E Stewar. Insulin-like growth factors (IGF-I and IGF-II) inhibit C2 skeletal myoblast differentiation and enhance TNF alpha-induced apoptosis. Journal of cellular physiology. vol 189. issue 2. 2001-10-25. PMID:11598906. |
a lower dose of tnf alpha (1 ng/ml) while not inducing apoptosis still inhibited myoblast differentiation by 56% +/- 12, (p < 0.001), indicating that induction of apoptosis is not the sole mechanism by which tnf alpha inhibits myoblast differentiation. |
2001-10-25 |
2023-08-12 |
Not clear |
| E J Foulstone, K A Meadows, J M Holly, C E Stewar. Insulin-like growth factors (IGF-I and IGF-II) inhibit C2 skeletal myoblast differentiation and enhance TNF alpha-induced apoptosis. Journal of cellular physiology. vol 189. issue 2. 2001-10-25. PMID:11598906. |
unexpectedly, co-incubation of igf-i or igf-ii with 1 ng/ml tnf alpha enhanced the inhibition of differentiation and induced apoptosis. |
2001-10-25 |
2023-08-12 |
Not clear |
| E J Foulstone, K A Meadows, J M Holly, C E Stewar. Insulin-like growth factors (IGF-I and IGF-II) inhibit C2 skeletal myoblast differentiation and enhance TNF alpha-induced apoptosis. Journal of cellular physiology. vol 189. issue 2. 2001-10-25. PMID:11598906. |
in the absence of tnf alpha, the igfs delay differentiation and promote myoblast proliferation whereas in the presence of tnf alpha the igfs induce apoptosis. |
2001-10-25 |
2023-08-12 |
Not clear |
| M J Gough, A A Melcher, A Ahmed, M R Crittenden, D S Riddle, E Linardakis, A N Ruchatz, L M Emiliusen, R G Vil. Macrophages orchestrate the immune response to tumor cell death. Cancer research. vol 61. issue 19. 2001-10-18. PMID:11585761. |
using hsvtk suicide gene therapy, we showed that macrophages can distinguish between tumor cells dying through classical apoptosis and tumor cells engineered to die through nonapoptotic mechanisms, resulting in secretion of either immunosuppressive cytokines (interleukin 10 and transforming growth factor beta) or inflammatory cytokines (tumor necrosis factor alpha or interleukin 1beta), respectively. |
2001-10-18 |
2023-08-12 |
mouse |
| R Manchanda, J M Kim, B K Tsan. Role of prostaglandins in the suppression of apoptosis in hen granulosa cells by transforming growth factor alpha. Reproduction (Cambridge, England). vol 122. issue 1. 2001-10-11. PMID:11425333. |
role of prostaglandins in the suppression of apoptosis in hen granulosa cells by transforming growth factor alpha. |
2001-10-11 |
2023-08-12 |
Not clear |
| R G Wickremasinghe, K Ganeshaguru, D T Jones, C Lindsay, V J Spanswick, J A Hartley, M Wadhwa, R Thorpe, A V Hoffbrand, H G Prentice, A B Meht. Autologous plasma activates Akt/protein kinase B and enhances basal survival and resistance to DNA damage-induced apoptosis in B-chronic lymphocytic leukaemia cells. British journal of haematology. vol 114. issue 3. 2001-10-11. PMID:11552986. |
experiments using neutralizing antibodies suggested that the protective actions of plasma could not be accounted for by interleukin 4, the interferons alpha or gamma or stromal cell-derived factor 1, each of which have been shown to protect b-cll cells from apoptosis in vitro. |
2001-10-11 |
2023-08-12 |
Not clear |
| A D Schimmer, D W Hedley, S Chow, N A Pham, A Chakrabartty, D Bouchard, T W Mak, M R Trus, M D Minde. The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2. Cell death and differentiation. vol 8. issue 7. 2001-10-04. PMID:11464217. |
the bh3 domain of bad fused to the antennapedia peptide induces apoptosis via its alpha helical structure and independent of bcl-2. |
2001-10-04 |
2023-08-12 |
Not clear |
| H Nakae, K Narita, S End. Soluble Fas and soluble Fas ligand levels in patients with acute hepatic failure. Journal of critical care. vol 16. issue 2. 2001-10-04. PMID:11481600. |
we measured tumor necrosis factor alpha (tnf-alpha), soluble fasl (sfasl), and soluble fas (sfas) in patients with acute hepatic failure to determine the relation between such failure and apoptosis. |
2001-10-04 |
2023-08-12 |
Not clear |
| T Aizawa, T Kon, T A Einhorn, L C Gerstenfel. Induction of apoptosis in chondrocytes by tumor necrosis factor-alpha. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 19. issue 5. 2001-10-04. PMID:11562122. |
tumor necrosis factor alpha (tnf-alpha) induces apoptosis in a number of cell types and plays an essential role in bone remodeling, both stimulating the proliferation of osteoblasts and activating osteoclasts. |
2001-10-04 |
2023-08-12 |
human |
| J Mi, Z Y Li, S Ni, D Steinwaerder, A Liebe. Induced apoptosis supports spread of adenovirus vectors in tumors. Human gene therapy. vol 12. issue 10. 2001-09-27. PMID:11440627. |
expression of a dominant-negative i-kappab from this vector sensitized tumor cells to recombinant human tumor necrosis factor alpha (tnf-alpha)-mediated apoptosis. |
2001-09-27 |
2023-08-12 |
human |
| J Soboloff, H Sasaki, B K Tsan. Follicular stage-dependent tumor necrosis factor alpha-induced hen granulosa cell integrin production and survival in the presence of transforming growth factor alpha in vitro. Biology of reproduction. vol 65. issue 2. 2001-09-27. PMID:11466216. |
however, fluorometric analysis indicated that the primary type of cell death exhibited by f5,6 granulosa cells during extended culture and attenuated by the presence of tnf alpha and tgf alpha was necrosis and not apoptosis. |
2001-09-27 |
2023-08-12 |
Not clear |
| M G Neuma. Apoptosis in diseases of the liver. Critical reviews in clinical laboratory sciences. vol 38. issue 2. 2001-09-20. PMID:11347718. |
apoptosis, or programmed cell death, and the elimination of apoptotic cells are crucial factors in the maintenance of liver health apoptosis allows hepatocytes to die without provoking a potentially harmful inflammatory response in contrast to necrosis, apoptosis is tightly controlled and regulated via several mechanisms, including fas/fas ligand interactions, the effects of cytokines such as tumor necrosis factor alpha (tnf-alpha) and transforming growth factor beta (tgf-beta), and the influence of pro- and antiapoptotic mitochondria-associated proteins of the b-cell lymphoma-2 (bcl-2) family. |
2001-09-20 |
2023-08-12 |
Not clear |