Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
R Tóth, E Szegezdi, U Reichert, J M Bernardon, S Michel, P Ancian, K Kis-Tóth, Z Macsári, L Fésüs, Z Szond. Activation-induced apoptosis and cell surface expression of Fas (CD95) ligand are reciprocally regulated by retinoic acid receptor alpha and gamma and involve nur77 in T cells. European journal of immunology. vol 31. issue 5. 2001-08-09. PMID:11465095. |
activation-induced apoptosis and cell surface expression of fas (cd95) ligand are reciprocally regulated by retinoic acid receptor alpha and gamma and involve nur77 in t cells. |
2001-08-09 |
2023-08-12 |
Not clear |
D Javelaud, F Besanço. NF-kappa B activation results in rapid inactivation of JNK in TNF alpha-treated Ewing sarcoma cells: a mechanism for the anti-apoptotic effect of NF-kappa B. Oncogene. vol 20. issue 32. 2001-08-09. PMID:11466617. |
pretreatment of control cells with the phosphatase inhibitor vanadate greatly prolonged jnk activation by tnf alpha and resulted in induction of apoptosis by this cytokine. |
2001-08-09 |
2023-08-12 |
Not clear |
D Javelaud, F Besanço. NF-kappa B activation results in rapid inactivation of JNK in TNF alpha-treated Ewing sarcoma cells: a mechanism for the anti-apoptotic effect of NF-kappa B. Oncogene. vol 20. issue 32. 2001-08-09. PMID:11466617. |
moreover, overexpression of a dominant-negative mutant of jnk1 decreased tnf alpha-induced apoptosis in cells expressing the super repressor of nf-kappa b, indicating that the sustained activation of jnk1 participated in death signaling triggered by tnf alpha. |
2001-08-09 |
2023-08-12 |
Not clear |
J P Kehrer, S S Biswal, E La, P Thuillier, K Datta, S M Fischer, J P Vanden Heuve. Inhibition of peroxisome-proliferator-activated receptor (PPAR)alpha by MK886. The Biochemical journal. vol 356. issue Pt 3. 2001-08-02. PMID:11389700. |
although jurkat cells express all ppar isoforms, various ppar alpha and ppar gamma agonists were unable to prevent mk886-induced apoptosis. |
2001-08-02 |
2023-08-12 |
mouse |
J P Kehrer, S S Biswal, E La, P Thuillier, K Datta, S M Fischer, J P Vanden Heuve. Inhibition of peroxisome-proliferator-activated receptor (PPAR)alpha by MK886. The Biochemical journal. vol 356. issue Pt 3. 2001-08-02. PMID:11389700. |
this is consistent with mk886 functioning as a non-competitive inhibitor of ppar alpha, but may also indicate that ppar alpha is not directly involved in mk886-induced apoptosis. |
2001-08-02 |
2023-08-12 |
mouse |
K Kimura, M Markowski, C Bowen, E P Gelman. Androgen blocks apoptosis of hormone-dependent prostate cancer cells. Cancer research. vol 61. issue 14. 2001-08-02. PMID:11454715. |
androgen inhibited apoptosis induced by both tumor necrosis factor alpha (tnf-alpha) and by fas activation with or without concomitant irradiation. |
2001-08-02 |
2023-08-12 |
Not clear |
Y Yang, J Z Cheng, S S Singhal, M Saini, U Pandya, S Awasthi, Y C Awasth. Role of glutathione S-transferases in protection against lipid peroxidation. Overexpression of hGSTA2-2 in K562 cells protects against hydrogen peroxide-induced apoptosis and inhibits JNK and caspase 3 activation. The Journal of biological chemistry. vol 276. issue 22. 2001-07-26. PMID:11279091. |
hgsta2 transfection does not affect the function of antioxidant enzymes including gpx activity toward h(2)o(2) suggesting that the alpha class gsts play an important role in regulation of the intracellular concentrations of the lipid peroxidation products that may be involved in the signaling mechanisms of apoptosis. |
2001-07-26 |
2023-08-12 |
human |
R J Clem, T T Sheu, B W Richter, W W He, N A Thornberry, C S Duckett, J M Hardwic. c-IAP1 is cleaved by caspases to produce a proapoptotic C-terminal fragment. The Journal of biological chemistry. vol 276. issue 10. 2001-07-19. PMID:11106668. |
although human c-iap1 and c-iap2 have been reported to possess antiapoptotic activity against a variety of stimuli in several mammalian cell types, we observed that full-length c-iap1 and c-iap2 failed to protect cells from apoptosis induced by bax overexpression, tumor necrosis factor alpha treatment or sindbis virus infection. |
2001-07-19 |
2023-08-12 |
human |
Y Minegishi, M E Conle. Negative selection at the pre-BCR checkpoint elicited by human mu heavy chains with unusual CDR3 regions. Immunity. vol 14. issue 5. 2001-07-19. PMID:11371364. |
when expressed in jurkat t cells with the ig(alpha)/ig(beta) signal transduction module, these aberrant mu heavy chains induce cell activation and apoptosis. |
2001-07-19 |
2023-08-12 |
human |
H Qian, D B Hausman, M M Compton, R J Martin, M A Della-Fera, D L Hartzell, C A Bail. TNFalpha induces and insulin inhibits caspase 3-dependent adipocyte apoptosis. Biochemical and biophysical research communications. vol 284. issue 5. 2001-07-19. PMID:11414707. |
to investigate this process, cultured rat adipocytes were treated with various concentrations of tumor necrosis factor alpha (tnfalpha) and/or insulin to determine the roles of these factors in adipocyte apoptosis. |
2001-07-19 |
2023-08-12 |
rat |
S Yamasaki, A Kawakami, T Nakashima, H Nakamura, M Kamachi, S Honda, Y Hirai, A Hida, H Ida, K Migita, Y Kawabe, T Koji, I Furuichi, T Aoyagi, K Eguch. Importance of NF-kappaB in rheumatoid synovial tissues: in situ NF-kappaB expression and in vitro study using cultured synovial cells. Annals of the rheumatic diseases. vol 60. issue 7. 2001-07-12. PMID:11406522. |
to examine whether inhibition of nf-kappab induces apoptosis of human synovial cells stimulated by tumour necrosis factor alpha (tnfalpha), interleukin 1beta (il1beta), and anti-fas monoclonal antibody (mab). |
2001-07-12 |
2023-08-12 |
human |
V Cottin, A A Van Linden, D W Riche. Phosphorylation of the tumor necrosis factor receptor CD120a (p55) recruits Bcl-2 and protects against apoptosis. The Journal of biological chemistry. vol 276. issue 20. 2001-07-05. PMID:11278725. |
ligation of the tumor necrosis factor alpha receptor cd120a initiates responses as diverse as apoptosis and the expression of nf-kappab-dependent pro-survival genes. |
2001-07-05 |
2023-08-12 |
Not clear |
H H Zhang, S Kumar, A H Barnett, M C Egg. Dexamethasone inhibits tumor necrosis factor-alpha-induced apoptosis and interleukin-1 beta release in human subcutaneous adipocytes and preadipocytes. The Journal of clinical endocrinology and metabolism. vol 86. issue 6. 2001-07-05. PMID:11397893. |
apoptosis induced by tnf alpha was reduced to control levels (p < 0.01) by dex. |
2001-07-05 |
2023-08-12 |
human |
H H Zhang, S Kumar, A H Barnett, M C Egg. Dexamethasone inhibits tumor necrosis factor-alpha-induced apoptosis and interleukin-1 beta release in human subcutaneous adipocytes and preadipocytes. The Journal of clinical endocrinology and metabolism. vol 86. issue 6. 2001-07-05. PMID:11397893. |
in obesity, glucocorticoids may reduce tnf alpha actions in adipose tissue by inhibiting tnf alpha-induced apoptosis, il-1 beta release, and tnf alpha expression. |
2001-07-05 |
2023-08-12 |
human |
A M Steff, S Trop, M Maira, J Drouin, P Hug. Opposite ability of pre-TCR and alpha beta TCR to induce apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 8. 2001-06-28. PMID:11290785. |
opposite ability of pre-tcr and alpha beta tcr to induce apoptosis. |
2001-06-28 |
2023-08-12 |
Not clear |
Y S Zhang, Z G T. Regulation of alpha 1-adrenoceptor on rat hepatocyte apoptosis induced by D-galactosamine and lipopolysaccharide. Acta pharmacologica Sinica. vol 21. issue 7. 2001-06-28. PMID:11360671. |
regulation of alpha 1-adrenoceptor on rat hepatocyte apoptosis induced by d-galactosamine and lipopolysaccharide. |
2001-06-28 |
2023-08-12 |
rat |
Y S Zhang, Z G T. Regulation of alpha 1-adrenoceptor on rat hepatocyte apoptosis induced by D-galactosamine and lipopolysaccharide. Acta pharmacologica Sinica. vol 21. issue 7. 2001-06-28. PMID:11360671. |
to study the regulation of alpha 1-adrenoceptor on the biochemical changes involved in hepatocyte apoptosis induced by d-galactosamine (d-galn) and lipopolysaccharide (lps). |
2001-06-28 |
2023-08-12 |
rat |
M L Jelachich, H L Lipto. Theiler's murine encephalomyelitis virus induces apoptosis in gamma interferon-activated M1 differentiated myelomonocytic cells through a mechanism involving tumor necrosis factor alpha (TNF-alpha) and TNF-alpha-related apoptosis-inducing ligand. Journal of virology. vol 75. issue 13. 2001-06-28. PMID:11390594. |
theiler's murine encephalomyelitis virus induces apoptosis in gamma interferon-activated m1 differentiated myelomonocytic cells through a mechanism involving tumor necrosis factor alpha (tnf-alpha) and tnf-alpha-related apoptosis-inducing ligand. |
2001-06-28 |
2023-08-12 |
mouse |
W Wick, C Grimmel, C Wild-Bode, M Platten, M Arpin, M Welle. Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by BCL-2 and transforming growth factor-beta2. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 10. 2001-06-21. PMID:11331365. |
glioma cells expressing dominant-negative ezrins exhibit a shift of the bcl-2/bax rheostat toward apoptosis, reduced alpha(v)beta(3) integrin expression and reduced matrix metalloproteinase (mmp) expression and activity. |
2001-06-21 |
2023-08-12 |
mouse |
B Nagy, W C Yeh, T W Mak, S M Chiu, D Separovi. FADD null mouse embryonic fibroblasts undergo apoptosis after photosensitization with the silicon phthalocyanine Pc 4. Archives of biochemistry and biophysics. vol 385. issue 1. 2001-06-21. PMID:11361017. |
oxidative stress, such as photodynamic therapy with the silicon phthalocyanine pc 4 (pc 4-pdt), can induce apoptosis and tumor necrosis factor alpha (tnf) production. |
2001-06-21 |
2023-08-12 |
mouse |