| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Deng, E Goluszko, P Christados. Fas/Fas ligand pathway, apoptosis, and clonal anergy involved in systemic acetylcholine receptor T cell epitope tolerance. Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 5. 2001-04-26. PMID:11207304. |
a high dose of alpha 146--162 peptide in ifa in achr-immunized mice induced apoptosis of bv6 cells. |
2001-04-26 |
2023-08-12 |
mouse |
| C Deng, E Goluszko, P Christados. Fas/Fas ligand pathway, apoptosis, and clonal anergy involved in systemic acetylcholine receptor T cell epitope tolerance. Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 5. 2001-04-26. PMID:11207304. |
the findings implicate the possible role of fas-/fas ligand-mediated apoptosis and the resulting clonal anergy as the mechanisms of high dose achr alpha 146--162 peptide-induced tolerance on cd4 cells. |
2001-04-26 |
2023-08-12 |
mouse |
| M Nieda, A Nicol, Y Koezuka, A Kikuchi, N Lapteva, Y Tanaka, K Tokunaga, K Suzuki, N Kayagaki, H Yagita, H Hirai, T Juj. TRAIL expression by activated human CD4(+)V alpha 24NKT cells induces in vitro and in vivo apoptosis of human acute myeloid leukemia cells. Blood. vol 97. issue 7. 2001-04-26. PMID:11264173. |
trail expression by activated human cd4(+)v alpha 24nkt cells induces in vitro and in vivo apoptosis of human acute myeloid leukemia cells. |
2001-04-26 |
2023-08-12 |
human |
| M Nieda, A Nicol, Y Koezuka, A Kikuchi, N Lapteva, Y Tanaka, K Tokunaga, K Suzuki, N Kayagaki, H Yagita, H Hirai, T Juj. TRAIL expression by activated human CD4(+)V alpha 24NKT cells induces in vitro and in vivo apoptosis of human acute myeloid leukemia cells. Blood. vol 97. issue 7. 2001-04-26. PMID:11264173. |
we also show that myeloid leukemia cells from patients with aml m4, but not from patients with aml m0 or m1, undergo apoptosis following culture with trail-expressing autologous or allogeneic healthy donor v alpha 24nkt cells. |
2001-04-26 |
2023-08-12 |
human |
| M Nieda, A Nicol, Y Koezuka, A Kikuchi, N Lapteva, Y Tanaka, K Tokunaga, K Suzuki, N Kayagaki, H Yagita, H Hirai, T Juj. TRAIL expression by activated human CD4(+)V alpha 24NKT cells induces in vitro and in vivo apoptosis of human acute myeloid leukemia cells. Blood. vol 97. issue 7. 2001-04-26. PMID:11264173. |
apoptosis of aml m4 leukemia cells from patient peripheral blood was almost completely blocked by a neutralizing monoclonal antibody against trail, indicating that trail on v alpha 24nkt cells is essential for the induction of apoptosis in aml m4 leukemia cells. |
2001-04-26 |
2023-08-12 |
human |
| M Nieda, A Nicol, Y Koezuka, A Kikuchi, N Lapteva, Y Tanaka, K Tokunaga, K Suzuki, N Kayagaki, H Yagita, H Hirai, T Juj. TRAIL expression by activated human CD4(+)V alpha 24NKT cells induces in vitro and in vivo apoptosis of human acute myeloid leukemia cells. Blood. vol 97. issue 7. 2001-04-26. PMID:11264173. |
a nonobese diabetic-severe combined immunodeficient human leukemia (aml m4) model showed that human activated cd4(+)v alpha 24nkt cells induced apoptosis of human leukemia cells in vivo. |
2001-04-26 |
2023-08-12 |
human |
| M Nieda, A Nicol, Y Koezuka, A Kikuchi, N Lapteva, Y Tanaka, K Tokunaga, K Suzuki, N Kayagaki, H Yagita, H Hirai, T Juj. TRAIL expression by activated human CD4(+)V alpha 24NKT cells induces in vitro and in vivo apoptosis of human acute myeloid leukemia cells. Blood. vol 97. issue 7. 2001-04-26. PMID:11264173. |
this is the first evidence that activated v alpha 24nkt cells express trail and that trail causes apoptosis of monocytic leukemia cells from patients with aml m4 in vitro and in vivo. |
2001-04-26 |
2023-08-12 |
human |
| D Bernard, B Quatannens, A Begue, B Vandenbunder, C Abbadi. Antiproliferative and antiapoptotic effects of crel may occur within the same cells via the up-regulation of manganese superoxide dismutase. Cancer research. vol 61. issue 6. 2001-04-26. PMID:11289144. |
inconsistent with this assumption, we show here that crel is able in one cell type to inhibit proliferation, protect against apoptosis induced by tumor necrosis factor alpha (tnf-alpha) + cycloheximide (chx), and increase the basal rate of apoptosis. |
2001-04-26 |
2023-08-12 |
Not clear |
| K N Pennington, J A Taylor, G D Bren, C V Pay. IkappaB kinase-dependent chronic activation of NF-kappaB is necessary for p21(WAF1/Cip1) inhibition of differentiation-induced apoptosis of monocytes. Molecular and cellular biology. vol 21. issue 6. 2001-04-19. PMID:11238929. |
the differentiation-induced apoptosis was found to be dependent on tumor necrosis factor alpha. |
2001-04-19 |
2023-08-12 |
Not clear |
| M Mejillano, M Yamamoto, A L Rozelle, H Q Sun, X Wang, H L Yi. Regulation of apoptosis by phosphatidylinositol 4,5-bisphosphate inhibition of caspases, and caspase inactivation of phosphatidylinositol phosphate 5-kinases. The Journal of biological chemistry. vol 276. issue 3. 2001-04-12. PMID:11042212. |
overexpression of phosphatidylinositol phosphate 5-kinase alpha (pip5kialpha), which synthesizes pip2, suppressed apoptosis, whereas a kinase-deficient mutant did not. |
2001-04-12 |
2023-08-12 |
Not clear |
| E Hatano, B L Bennett, A M Manning, T Qian, J J Lemasters, D A Brenne. NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis. Gastroenterology. vol 120. issue 5. 2001-04-12. PMID:11266388. |
hepatocyte apoptosis is induced by tumor necrosis factor alpha (tnf-alpha) and fas ligand. |
2001-04-12 |
2023-08-12 |
mouse |
| P Tesarová, J Kvasnicka, A Umlaufová, H Homolková, M Jirsa, V Tesa. Soluble TNF and IL-2 receptors in patients with breast cancer. Medical science monitor : international medical journal of experimental and clinical research. vol 6. issue 4. 2001-04-05. PMID:11208388. |
tnf alpha may mediate apoptosis and necrosis of cancer cells, while the exact role of il-2 remains to be elucidated. |
2001-04-05 |
2023-08-12 |
Not clear |
| J M van den Berg, S Weyer, J J Weening, D Roos, T W Kuijper. Divergent effects of tumor necrosis factor alpha on apoptosis of human neutrophils. Journal of leukocyte biology. vol 69. issue 3. 2001-03-29. PMID:11261795. |
divergent effects of tumor necrosis factor alpha on apoptosis of human neutrophils. |
2001-03-29 |
2023-08-12 |
human |
| M L Colamussi, P Secchiero, A Gonelli, M Marchisio, G Zauli, S Capitan. Stromal derived factor-1 alpha (SDF-1 alpha) induces CD4+ T cell apoptosis via the functional up-regulation of the Fas (CD95)/Fas ligand (CD95L) pathway. Journal of leukocyte biology. vol 69. issue 2. 2001-03-29. PMID:11272277. |
stromal derived factor-1 alpha (sdf-1 alpha) induces cd4+ t cell apoptosis via the functional up-regulation of the fas (cd95)/fas ligand (cd95l) pathway. |
2001-03-29 |
2023-08-12 |
Not clear |
| A Forte, G Di Micco, U Galderisi, F M Guarino, M Cipollaro, M De Feo, R Gregorio, M R Bianco, C Vollono, F Esposito, L Berrino, F Angelini, A Renzulli, M Cotrufo, F Rossi, A Cascin. Molecular analysis of arterial stenosis in rat carotids. Journal of cellular physiology. vol 186. issue 2. 2001-03-22. PMID:11169467. |
at different times following arterial damage, the pattern of expression of genes already known to be involved in the proliferation, differentiation, and apoptosis of smooth muscle cells (c-myc, angiotensin ii receptor 1, bcl-2 and bax alpha), as well as of rb and rb2 genes, whose pattern of expression after arterial injury has not yet been reported, was analyzed by semi-quantitative reverse transcription-polymerase chain reaction technique. |
2001-03-22 |
2023-08-12 |
rat |
| M Igarashi, Y Kitada, H Yoshiyama, A Takagi, T Miwa, Y Kog. Ammonia as an accelerator of tumor necrosis factor alpha-induced apoptosis of gastric epithelial cells in Helicobacter pylori infection. Infection and immunity. vol 69. issue 2. 2001-03-15. PMID:11159973. |
in the presence of tumor necrosis factor alpha (tnf-alpha), however, a marked acceleration of apoptosis was found in this coculture. |
2001-03-15 |
2023-08-12 |
human |
| J J Jimenez, W Jy, L M Mauro, L L Horstman, Y S Ah. Elevated endothelial microparticles in thrombotic thrombocytopenic purpura: findings from brain and renal microvascular cell culture and patients with active disease. British journal of haematology. vol 112. issue 1. 2001-03-15. PMID:11167788. |
both cell lines generated procoagulant emps when cultured with inducers of activation (tumour necrosis factor alpha; tnf-alpha) or apoptosis (mitomycin c). |
2001-03-15 |
2023-08-12 |
Not clear |
| T Hayashi, D Faustma. A role for NF-kappaB and the proteasome in autoimmunity. Archivum immunologiae et therapiae experimentalis. vol 48. issue 5. 2001-03-08. PMID:11140462. |
this defect both prevents the proteolytic processing required for the production and activation of the transcription factor nuclear factor kappab (nf-kappab), which plays important roles in immune and inflammatory responses, as well as increases the susceptibility of the affected cells to apoptosis induced by tumor necrosis factor alpha (tnf-alpha). |
2001-03-08 |
2023-08-12 |
mouse |
| K Miyoshi, T Katayama, K Imaizumi, M Taniguchi, Y Mori, J Hitomi, D Yui, T Manabe, F Gomi, T Yoneda, M Tohyam. Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line. Brain research. Molecular brain research. vol 85. issue 1-2. 2001-03-08. PMID:11146108. |
morphological and biochemical studies using a dominant-negative form of mouse ire1 alpha have revealed that cell death caused by er stress can be attributed to apoptosis, and that the downregulation of the upr enhances the apoptotic process in the mouse neuroblastoma cell line, neuro2a. |
2001-03-08 |
2023-08-12 |
mouse |
| M K Tietze, T Wuestefeld, Y Paul, L Zender, C Trautwein, M P Manns, S Kubick. IkappaBalpha gene therapy in tumor necrosis factor-alpha- and chemotherapy-mediated apoptosis of hepatocellular carcinomas. Cancer gene therapy. vol 7. issue 10. 2001-02-15. PMID:11059688. |
because hepatocellular carcinomas (hccs) are one of the most resistant tumors to systemic chemotherapy, we investigated the activation of nfkappab and the consequence of its inhibition by an ikappabalpha-super repressor during tumor necrosis factor alpha (tnfalpha)- and chemotherapy-induced apoptosis in hcc cell lines. |
2001-02-15 |
2023-08-12 |
Not clear |